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Diss Factsheets
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EC number: 922-153-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 16-Jan-1992 to 18-Jan-1992
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- The reliability rating is a 1 because the study followed a standard guideline, which describes a procedure designed to evaluate this endpoint, and the results were reviewed for reliability and assessed as valid. The study was also conducted under GLP.
- Justification for type of information:
- The justification for read across is provided as an attachment in IUCLID Section 13.
- Reason / purpose for cross-reference:
- read-across: supporting information
- Qualifier:
- according to guideline
- Guideline:
- EPA OPP 72-2 (Aquatic Invertebrate Acute Toxicity Test)
- Deviations:
- no
- GLP compliance:
- yes
- Analytical monitoring:
- yes
- Details on sampling:
- Samples were removed from the fresh solutions at initiation and on Day 1. Samples were also removed from the old solutions on Day 1.
- Vehicle:
- no
- Details on test solutions:
- Individual treatment solutions were prepared as either a water accommodated fraction (WAF) or serial dilution of a stock WAF. A WAF was prepared for the two highest treatments (1.0 and 4.0 mg/L) by adding test substance to 1.0 L of medium in a 1 liter flask, mixing for 24 hours, and then removing the WAF from below the surface using a siphon. The lower treatment solutions were prepared by making serial dilutions of a WAF prepared as described above at a loading of 1.0 mg/L. Serial dilutions were prepared for the lower treatment solutions because of the difficulty in accurately preparing the renewal solutions at these lower treatment levels. Each test solution was renewed after 24 hours with a freshly prepared WAF solution. Dilution water was laboratory blend water with a hardness of 40 to 48 mg/L CaCO3.
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Test organisms came from in-house cultures. Original source was Academy of Natural Sciences of Philadelphia, Division of Environmental Research, Philadelphia, PA, USA. Test organisms were <24 hours old from 16 day-old parents.
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Post exposure observation period:
- None
- Hardness:
- 40 to 48 mg/L as CaCO3.
- Test temperature:
- Test temperature was 19.6 Deg C.
- pH:
- The pH ranged from 7.8 to 8.0.
- Dissolved oxygen:
- Dissolved oxygen was 9.0 to 9.2 mg/L for "new" solutions and 8.3 to 9.1 mg/L for "old" solutions.
- Salinity:
- freshwater
- Nominal and measured concentrations:
- Nominal treatment levels were control, 0.01, 0.05, 0.1, 0.5, 1.0, and 4.0 mg/L, which measured non detected, NA (not analyzed), NA, 0.051, 0.228, 0.814, and 3.74 mg/L, respectively.
- Details on test conditions:
- Lighting was 67 to 76 ft candles with 16 hrs light and 8 hrs dark. Test vessels were 250 ml glass beakers in duplicate filled with 240 ml of solution. All test vessels were covered. Each replicate contained 10 organisms.
- Reference substance (positive control):
- no
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EL50
- Effect conc.:
- 1.1 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: 95% CI = 0.95 - 1.8
- Details on results:
- 48-hour EL50 = 1.1 mg/L (95% CI 0.95 to 1.8 mg/L) based upon nominal values 48-hour EC50 = 0.95 mg/L (95% CI 0.76 to 1.48 mg/L) based upon measured values.
- Reported statistics and error estimates:
- The 48-hr EC50 values were determined using the Probit Procedure of SAS.
- Validity criteria fulfilled:
- yes
- Conclusions:
- Water accommodated fractions of hydrocarbons, C10-C13, aromatics, >1% naphthalene, produced a 48-hour EL50 value of 1.1 mg/l with the water flea (Daphnia magna).
- Executive summary:
Water accommodated fractions of hydrocarbons, C10-C13, aromatics, >1% naphthalene, produced a 48-hour EL50 value of 1.1 mg/l with the water flea (Daphnia magna).
Reference
Nominal Loading Total
or Concentration Daphnia Immobilized
(mg/L) (@ 24, 48 hrs)*
Control 0, 0
0.01 (nominal)** 1, 1
0.05 (nominal)** 0, 0
0.05 (measured) 0, 0
0.23 (measured) 0, 1
0.81 (measured) 0, 7
3.74 (measured) 17, 20
*20 daphnids added to each of the control and treatment levels at test initiation.
**Test solutions were not analyzed or included in the statistical analyses due to lack of significant mortality.
Description of key information
Water accommodated fractions of hydrocarbons, C10-C13, aromatics, >1% naphthalene, produced a 48-hour EL50 value of 1.1 mg/L with the water flea (Daphnia magna).
This data is read across to Hydrocarbons, C11-C15, aromatics, <1% naphthalene.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.