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EC number: 297-626-1 | CAS number: 93685-78-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Endpoint summary
Administrative data
Description of key information
Tetrabutene (mixture of C16 and C20 olefin isomers) was found to be non irritating to the skin. However C8 and C12 butylene oligomers using occlusive dressings were found to be irritating to rabbit skin. In a study where a semi occlusive dressing was used, 2,4,4, TMP (a C8 olefin) was found to be non-irritating. However another C8 substance, diisobutylene was found to be moderately irritating to rabbit skin using semi-occlusive conditions.
In four representative studies it was found that the test materials were not irritating to the rabbit eye.
There are no specific studies on respiratory tract irritation but there was no evidence of respiratory tract irritation in a 90 day inhalation with isooctene.
Key value for chemical safety assessment
Additional information
Non-human data
Skin Irritation
Isooctene (CAS 11071-47-9, 18% n-octene; and 58% methylheptene and 24% dimethylhexene isomers) was found to be irritating to the skin of rabbits when applied for 4 hours under occlusive conditions (Huels AG, 1986 d). Both the erythema and edema were not fully reversible within 14 days of application. 2,4,4 TMP (a C8 olefin) was found not to be irritating to the skin of rabbits when applied for 4 hours under semi-occlusive conditions (HLS, 1996 c). In a further study with the C8 olefin diisobutylene using semi-occlusive conditions the test material was found to be moderately irritating to rabbit skin. Tributene (CAS 39133 -31 -8, a mixture of C12 olefin isomers) was also found to be irritating to the skin of rabbits when applied for 4 hours under occlusive conditions (Huels AG, 1986 e). Tetrabutene (CAS 9003 -29 -6, 70% of a mixture of C16 olefin isomers; 30% of a mixture of C20 olefin isomers) was not irritating to the skin of rabbits when applied for 4 hours under occlusive conditions (Huels AG, 1986 f).
Eye irritation
Instillation of 0.1 ml of undiluted isooctene (CAS 11071 -47 -9, 18% n-octene; and 58% methylheptene and 24% dimethylhexene isomers) was a non-irritant to the eyes of rabbits (Huels AG, 1986 g). 2,4,4-Trimethylpentene, another C8 olefin isomer, was also found not to be irritating to eyes of rabbits (HLS, 1996 d). Instillation of 0.1 ml of undiluted tributene (CAS 39133 -31 -8, a mixture of C12 olefin isomers) was a non-irritant to the eyes of rabbits (Huels AG, 1986 h). Instillation of 0.1 ml of undiluted tetrabutene (CAS 9003 -29 -6, 70% of a mixture of C16 olefin isomers; 30% of a mixture of C20 olefin isomers) was not irritating to the eyes of rabbits (Huels AG, 1986 i).
Respiratory Tract Irritation
No studies on respiratory tract irritation have been conducted with any butylene oligomers . In the combined subchronic vapour inhalation study with reproduction/developmental toxicity screening test in Wistar rats with isooctene (CAS 11071 -47 -9, BASF, 2007) there is no evidence of respiratory irritation.
Human data
No human information is available.
Justification for classification or non-classification
C16 and C20 olefin isomers have been tested and do not warrant classification as irritating to the skin under Dir 67/548/EEC or GHS/CLP. However there are two studies which indicate a classification of Xi R38 Irritating to the skin (DSD Dir 67/548/EEC ) and Category 2 H315 Causes skin irritation (CLP Reg (EC)1272/2008) is required for C8 and C12 butylene oligomers.
Butylene oligomers do not warrant classification as irritating to the eye under Dir 67/548/EEC or GHS/CLP.
Although there are no specific acute studies of respiratory irritation, longer term non human studies do not show any evidence of respiratory irritation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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