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EC number: 293-187-5 | CAS number: 91052-28-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Toxicity to soil microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The chemical safety assessment according to Annex I of Regulation (EC) No. 1907/2006 does not indicate the need to investigate further the toxicity to soil microorganisms.
Key value for chemical safety assessment
Additional information
No experimental data evaluating the toxicity of Glycerides, C14-18 and C16-18 unsaturated, mono-, di- and tri- (CAS No. 91052-28-7) to soil microorganisms are available.However, information gathered from several independent sources is combined in a Weight of Evidence approach, which is in accordance to the REACh Regulation (EC) No. 1907/2006, Annex XI General rules for adaptation of the standard testing regime set out in Annexes VII to X, 1.2, to cover the data requirements of Regulation (EC) No. 1907/2006, Annex IX). This approach provides enough evidence to state that this substance is unlikely to exert toxicity to soil microorganisms.
The test substance is characterized by a log Kow (> 4.65), indicating high potential for adsorption to soil particles. Tests with soil-dwelling organisms that feed on soil particles are therefore most relevant for the evaluation of soil toxicity of Glycerides, C14-18 and C16-18 unsaturated, mono-, di- and tri-.The toxicity of Glycerides, C14-18 and C16-18 unsaturated, mono-, di- and tri- (CAS No. 91052-28-7) to earthworms was evaluated by Moser (2012). Eisenia fetida was exposed to the test substance for 14 days at a concentration of 1000 mg/kg dw (limit test). No effects on survival or biomass were reported during the exposure period, leading to a NOEC (14 d) ≥ 1000 mg/kg dw.
According to Chapter R7.b of the Guidance on information requirements and chemical safety assessment (ECHA, 2008), a test on soil microbial activity will be additionally necessary for a valid PNEC derivation only if inhibition of sewage sludge microbial activity has occurred. The test performed on Pseudomonas putida (on a suitable read-across substance,1,2,3-propanetriyl trioleate(CAS No. 122-32-7)) showed no effectson cell multiplication up to the limit of the water solubility of the substance (EC50 (18 h) > 0.8 mg/L). The above-mentioned Guidance alsostates that for substances with a good biodegradation rate in a ready biodegradability test, inhibitory effects to aquatic microorganisms are not expected. This is the case for Glycerides, C14-18 and C16-18 unsaturated, mono-, di- and tri-(76.5% biodegradation after 28 days).
Additionally, literature data evaluating the effects of fatty acid esters, including one of the Glyceride category members (Glycerol tristearate, CAS No. 555-43-1) to soil microorganisms are available. Hita et al. (1996) investigated the degradation of the model molecule tristearin (Glycerol tristearate) in three different soils for 4 weeks. The amount of stearic acid increased in considerable amounts during the experiment showing the hydrolytic activity of lipases breaking the ester bonds. Furthermore, the investigation of ester fractions showed the generation of new alkanoic acids (methyl stearate, ethyl stearate and propyl stearate) which were not determined in the controls. Nevertheless the amounts were no longer present after 4 weeks, which leads to the assumption that degradation by soil microorganisms had occurred. The same was shown by Cecutti et al. (2002) and Banchio and Gramajo (1997) for other fatty acid esters. In the first test, one soil sample was chosen and incubated with methyl oleate (plant oil) for 120 days. Methyl oleate and its metabolites were completely degraded after 60 days. Streptomyces coelicolor, a common gram-positive soil bacterium uses fatty acids (C4-C18) as sole carbon end energy source indicating that fatty acids are not-toxic and can be used for catabolism (Banchio and Gramajo, 1997). The available literature data shows that soil microorganisms are capable to break-up ester bonds and degrade fatty acids in significant amounts. Moreover, the data indicated the non-toxic properties of fatty acids since they can be used as energy source.
Based on all the available information for the Weight of Evidence approach (in accordance with Annex XI, 1.2) effects on soil microorganisms are thus not expected to be of concern, and consequently, no further testing is required.
A detailed reference list is provided in the technical dossier (see IUCLID, section 13) and within the CSR.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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