Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 406-850-2 | CAS number: 133855-98-8 BAS 480 F
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The 5 months NOEAEC was determined to be 0.01 mg/L (nominal, analytically verified, BASF AG, 2003).
The 90 -d NOEC was determined to be 0.01 mg/L (nominal, analytically verified, BASF AG, 2004)
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 0.01 mg/L
Additional information
Experimental data are available for the assessment of the long-term toxicity of epoxiconazole to fish. The GLP Full-life cycle study with Pimephales promelas as a test organism was choosen as a key study for the assessment of the test substance. This flow-through test revealed growth as the most sensitive endpoint in test concentrations ≥ 0.001 mg/L and therefore, set the NOEAEC to 0.01mg/L (after 5 months). However, growth was reduced by less than 10-20% in the highest treatment group (30 µg/L). Hence, no additional ECx calculations were performed (BASF AG, rep.no.: 81F0307/005085, 2003).
The supporting fish full life cycle test on fathead minnow (Pimephales promelas) performed with the epoxiconazole. The study was originally conducted for clarification of open points in the mentioned above key FLC study (unclear effect on F2 sex ratio in the study by BASF AG, rep.no.: 81F0307/005085, 2003) and is hence specifically designed to that purpose with an unusual high spacing factor between test concentrations. ECx calculations could not be conducted for this study due to the low effects observed in the treatments (< 10%). The revealed 90-d NOEC was determined to be 0.01 mg/L (BASF AG, rep.no.: 2004/1003971, 2004).
The test concentrations were analytically verified in both studies.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.