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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 943-403-5 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
Coloured substances are often assumed to behave differently in the algal growth inhibition test due to shading of the algae. Coloured substances can absorb photosynthetically active light and hence limit growth of algal cultures. Absorption will be proportional to test substance concentration and as a consequence it can result in growth inhibition which is difficult to distinguish from inherent toxicity.
Several studies on algae conducted on dark dyes, including those with a modified test system for dye-stuffs, showed that the growth inhibition is mainly correlated to thereduced light absorption, caused by the stained water and not due to an effective toxicity of the dye.
A modified test design has been proposedby the cooperation of the Ecological and Toxicological Association of Dyes and Organic Pigments Manufacturers (ETAD), Memmert et al.[1], in order to eliminate the effect of shading. Nevertheless this method has some limitations, as it focuses on the shadow effect, giving no information on the real potential toxicity for algae of the tested substance.
Considering that the test substance is a dyestuff which could influence the photosynthesis capacity of algae cells in the test solution and in order to clarify the (eco)toxicological properties related to toxicity for aquatic plants, it was considered a test using Lemna gibba as a test organism (REACH&Colours Kft, 2015), according to the OECD Guideline 221, as suggested also in the Guidance on Information Requirements and Chemical Safety Assessment Chapter R.7b: Endpoint specific guidance (Version 2.0 November 2014), published by the European Chemical Agency.
Reference
[1]Memmert U, Motschi H, Inauen J, W. Uthrich V. Inhibition of algal growth caused by coloured test substances. ETAD Project E 3023. Ecological and Toxicological Association of Dyes and Organic Pigments Manufacturers, Basel, Switzerland, 1994.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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