Brief Profile

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Please be aware that the REACH registration parts of this Brief Profile are no longer maintained; they remain frozen as of 19th May 2023. All other data parts (substance identity, C&L, key regulatory lists etc. are up to date).

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
208-169-4
CAS no.:
513-79-1
Index number:
027-010-00-8
Molecular formula:
CCoO3
SMILES:
[Co++].[O-]C([O-])=O
InChI:
InChI=1S/CH2O3.Co/c2-1(3)4;/h(H2,2,3,4);/q;+2/p-2
Type of substance:
Mono constituent substance
Origin:
Inorganic
Registered compositions:
24
Of which contain:
12 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP01) approved by the European Union, this substance may cause cancer by inhalation, may damage fertility, is very toxic to aquatic life, is very toxic to aquatic life with long lasting effects, is suspected of causing genetic defects, may cause an allergic skin reaction and may cause allergy or asthma symptoms or breathing difficulties if inhaled.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is harmful if swallowed, causes serious eye damage and may cause damage to organs through prolonged or repeated exposure.

Breakdown of all 655 C&L notifications submitted to ECHA

Skin Sens. 1 H317 Harmonised Classification
Aquatic Acute 1 H400 Harmonised Classification
Muta. 2 H341 Harmonised Classification
Carc. 1B H350i Harmonised Classification
Aquatic Chronic 1 H410 Harmonised Classification
Resp. Sens. 1 H334 Harmonised Classification
Repr. 1B H360
Acute Tox. 4 H302
Resp. Sens. 1B H334
Repr. 1B H360Fd
Carc. 1A H350i
Aquatic Chronic 2 H411
Repr. 1B H360F
Repr. 1B H360FD
Eye Irrit. 2 H319
https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/more.png 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

  • C
Officially recognised in the EU as Carcinogenic (Harmonised C&L, Candidate list of SVHCs).
  • C
There is broad agreement in that a majority of data submitters agree this substance is Carcinogenic (100% of REACH registrations).
  • M
Suspected to be Mutagenic (Harmonised C&L).
  • R
Officially recognised in the EU as Toxic to Reproduction (Harmonised C&L, Candidate list of SVHCs).
  • R
There is broad agreement in that a majority of data submitters agree this substance is Toxic to Reproduction (100% of REACH registrations).
  • Ss
Officially recognised in the EU as Skin sensitising ( Harmonised C&L).
  • Ss
There is broad agreement in that a majority of data submitters agree this substance is Skin sensitising (100% of REACH registrations).
  • Sr
Officially recognised in the EU as Respiratory sensitising ( Harmonised C&L).
  • Sr
There is broad agreement in that a majority of data submitters agree this substance is Respiratory sensitising (100% of REACH registrations).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 11 active registrations under REACH, 1 Joint Submission(s) and 1 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Substance of very high concern (SVHC) and included in the candidate list for authorisation.
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Industrial accident prevention and reporting requirements have been established for this substance.
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 tonnes per annum.

This substance is used in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles.

Release to the environment of this substance can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal). Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance can be found in complex articles, with no release intended: machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines). This substance can be found in products with material based on: metal (e.g. cutlery, pots, toys, jewellery).

This substance is used in the following products: fertilisers.

This substance is used in the following areas: agriculture, forestry and fishing.

This substance is used in the following activities or processes at workplace: transfer of chemicals and transfer of substance into small containers.

Other release to the environment of this substance is likely to occur from: outdoor use as reactive substance and indoor use as reactive substance.

This substance is used in the following products: metal surface treatment products, pH regulators and water treatment products, laboratory chemicals and water treatment chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, handling of solid inorganic substances (e.g. ores and raw metal oxides, packaging/mixing/blending and weighing of metal powders), closed batch processing in synthesis or formulation, manual maintenance (cleaning and repair) of machinery, transfer of substance into small containers and closed, continuous processes with occasional controlled exposure.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

This substance is used in the following products: metal surface treatment products, laboratory chemicals, pH regulators and water treatment products, pharmaceuticals and water treatment chemicals.

This substance is used for the manufacture of: chemicals and fabricated metal products.

This substance is used in the following activities or processes at workplace: closed batch processing in synthesis or formulation, transfer of chemicals, batch processing in synthesis or formulation with opportunity for exposure, transfer of substance into small containers, closed, continuous processes with occasional controlled exposure and closed processes with no likelihood of exposure.

Release to the environment of this substance can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), in the production of articles, in processing aids at industrial sites and as processing aid.

This substance is used in the following activities or processes at workplace: closed processes with no likelihood of exposure, handling of solid inorganic substances (e.g. ores and raw metal oxides, packaging/mixing/blending and weighing of metal powders), transfer of chemicals, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure and mixing in open batch processes.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance and as an intermediate step in further manufacturing of another substance (use of intermediates).

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: obtain special instructions before use; in case of inadequate ventilation wear respiratory protection; wash parts of the body (as specified by manufacturer/supplier)in contact with substance thoroughly after handling; avoid release to the environment; use personal protective equipment as required.; do not handle until all safety precautions have been read and understood; do not breathe the dust, fume, gas, mist, vapours or spray; contaminated work clothing should not be allowed out of the workplace; avoid breathing the dust, fume, gas, mist, vapours or spray; do not eat, drink or smoke when using this product; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If swallowed: call a poison center or doctor/physician if you feel unwell. If eye irritation persists get medical advice/attention. Get medical advice/attention if you feel unwell. Wash contaminated clothing before reuse. If inhaled: if breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. If exposed or concerned: get medical advice/attention. If experiencing respiratory symptoms: call a poison center or doctor/physician. Immediately call a poison center or doctor/physician. Collect spillage. If skin irritation or a rash occurs: get medical advice/attention. If on skin: wash with soap and water. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing. Follow specific treatment (see label). Rinse the mouth.

Storage statements

Store this substance locked up.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • ALBEMARLE CATALYSTS COMPANY B.V., Nieuwendammerkade 1-3 PO Box 37650 1030 BE Amsterdam Netherlands
  • BLUESTONE METALS & CHEMICALS EUROPE S.L., c/ Pascual y Genis 1 46002 Valencia Spain
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Glencore Nikkelverk AS, Vesterveien 31 4606 Kristiansand Norway
  • Jervois Finland Oy, PL 286 67101 Kokkola Finland
  • Johnson Matthey Chemicals GmbH, Wardstrasse 17 D-46446 Emmerich am Rhein Germany
  • Sibanye-Stillwater Sandouville Refinery, Zone industrielle portuaire du Havre - Port 5059 76430 Sandouville France
  • Umicore Finland Oy, Kobolttiaukio 1 67900 KOKKOLA Finland
  • Umicore NV/SA, Rue du Marais 31 1000 Brussels Belgium
  • Yordas GmbH, Äuβere Nürnberger Straβe 62 91301 Forchheim Germany
  • BASF Nederland B.V., Velperplein 23 6811 AH Arnhem Netherlands
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • HH Compliance Ltd, Rubicon Building CIT Campus T12 Y275 Bishopstown Cork Ireland
  • Toda kogyo Europe GmbH, Marienstr.32 40210 Dusseldorf Nordrhein-Westfalen Germany
  • Vale Europe Limited, Acton Refinery Bashley Road NW10 6SN London GB United Kingdom
  • Vital Materials Belgium, Rue de la station 67 1495 Tilly Région wallonne Belgium

Substance names and other identifiers

Cobalt carbonate
EC Inventory, C&L Inventory, REACH pre-registration, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work
Cobalt carbonate
C&L Inventory, REACH pre-registration, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work
Cobalt(II) carbonate
Candidate list
carbonat de cobalt (ro)
C&L Inventory
carbonate de cobalt (fr)
C&L Inventory
carbonato de cobalto (es)
C&L Inventory
carbonato de cobalto (pt)
C&L Inventory
carbonato di cobalto (it)
C&L Inventory
cobaltcarbonat (da)
C&L Inventory
Cobaltcarbonat (de)
C&L Inventory
karbonat tal-kobalt (mt)
C&L Inventory
kobalt-karbonát (hu)
C&L Inventory
kobalta karbonāts (lv)
C&L Inventory
kobaltcarbonaat (nl)
C&L Inventory
kobalto karbonatas (lt)
C&L Inventory
kobaltov karbonat (hr)
C&L Inventory
kobaltov karbonat (sl)
C&L Inventory
koboltkarbonat (no)
C&L Inventory
koboltkarbonat (sv)
C&L Inventory
Kobolttikarbonaatti (fi)
C&L Inventory
koobaltkarbonaat (et)
C&L Inventory
uhličitan kobaltnatý (cs)
C&L Inventory
uhličitan kobaltnatý (sk)
C&L Inventory
węglan kobaltu(II) (pl)
C&L Inventory
ανθρακικό κοβάλτιο (el)
C&L Inventory
кобалтов карбонат (bg)
C&L Inventory
Cobalt (II) carbonate
C&L Inventory
Cobalt Carbonate
C&L Inventory, Registration dossier
Cobalt Carbonate
C&L Inventory, Registration dossier
cobalt(2+) carbonate
C&L Inventory, Registration dossier
Cobalt(II)carbonat
C&L Inventory
cobalte carbonate
C&L Inventory
lambda2-cobalt(2+) carbonate
Other
λ²-cobalt(2+) carbonate
Registration dossier
Cobalt Hydroxycarbonate
Registration dossier
Impure Cobalt Carbonate
Registration dossier
Intermediate Product of Cobalt Metallurgy (IPCM)
Registration dossier
ShepCo Carbonate CTG
Registration dossier
ShepCo Carbonate CTG1
Registration dossier
ShepCo Carbonate CTG2
Registration dossier
ShepCo Carbonate CTG3
Registration dossier
ShepCo Carbonate CTG4
Registration dossier
ShepCo Carbonate FG
Registration dossier
ShepCo Carbonate FG1
Registration dossier
ShepCo Carbonate FG2
Registration dossier
ShepCo Carbonate FG3
Registration dossier
ShepCo Carbonate FG4
Registration dossier
ShepCo Carbonate TG
Registration dossier
ShepCo Carbonate TG1
Registration dossier
027-010-00-8
Index number
C&L Inventory
513-79-1
CAS number
EC Inventory, C&L Inventory, Candidate list, Registration dossier, REACH pre-registration, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 3 studies submitted
  • 3 studies processed
C Physical state at 20°C and 1013 hPa
Solid (100%) [3]
C Form
Crystalline (100%) [3]
C Odour
Other (100%) [1]
C Substance type
Inorganic (100%) [3]

Type of Study provided
Studies with data
Key study 2 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Physical state at 20°C and 1013 hPa
Solid (100%)
Form
Solid: crystalline (100%)
Colour
red (100%)

Melting/freezing point

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Boiling point

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Density

Study results
  • 5 studies submitted
  • 5 studies processed
R Density
4.13 - 4.2 g/cm³ @ 20 °C [4]
R Relative density
4.13 - 4.2 @ 20 °C [2]

Type of Study provided
Studies with data
Key study 1 4
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Relative density at 20°C
4.17

Vapour pressure

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Vapour pressure
0 Pa @ 20 °C

Partition coefficient

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Water solubility

Study results
  • 11 studies submitted
  • 11 studies processed
R Water solubility (mass/vol.)
2.96 - 1 800 000 µg/L @ 15 - 37 °C and pH 5.85 - 7.95 [69]

Type of Study provided
Studies with data
Key study 11
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Water solubility
12.98 - 11 430 µg/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 13 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 6
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 5
Exposure cons.
Other 2
C Summaries
  • 3 summaries submitted
  • 2 summaries processed
Flammability
Not classified (100%)

Explosiveness

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other 1
C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Oxidising
Non oxidising (67%), No (33%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 3
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water - screening tests

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified 1
Exposure cons.
Other 1
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Biodegradation in water
Under test conditions no biodegradation observed (100%)

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 194 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 72
Supporting study 17
Weight of evidence
Other 1 104
Data waiving
no waivers
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Study results
  • 27 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 3 2
Weight of evidence
Other 2 20
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Adsorption/desorption

Study results
  • 46 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study 2 6
Weight of evidence 8 28
Other
Data waiving
no waivers
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Distribution modelling

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other

No summary exists for this scientific endpoint

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 2 summaries submitted
  • 2 summaries processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 620 - 1 060 ng/L (2)
Intermittent releases (freshwater) -
Marine water 2.36 µg/L (2)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 370 µg/L (2)
Sediment (freshwater) 53.8 mg/kg sediment dw (2)
Sediment (marine water) 69.8 mg/kg sediment dw (2)
Hazard for Air
Air No hazard identified (2)
Hazard for Terrestrial Organism
Soil 10.9 mg/kg soil dw (2)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (2)

Short–term toxicity to fish

Study results
  • 52 studies submitted
  • 12 studies processed
P/RResults
LC50 (4 days) 1.512 - 85.3 mg/L [16]
NOEC (4 days) 656.8 - 53 900 µg/L [16]
LOEC (4 days) 1.43 - 88.7 mg/L [16]

Type of Study provided
Studies with data
Key study 12
Supporting study 11
Weight of evidence 2
Other 26 1
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 42 studies submitted
  • 14 studies processed
P/RResults
NOEC (81 days) 2.2 mg/L [10]
NOEC (34 days) 210 - 790 µg/L [6]
NOEC (33 days) 1.02 - 2.14 mg/L [6]
NOEC (28 days) 31.196 mg/L [6]
NOEC (7 days) 76.9 - 3 569.6 µg/L [72]

Type of Study provided
Studies with data
Key study 14
Supporting study 18
Weight of evidence
Other 8 2
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 182 studies submitted
  • 78 studies processed
P/RResults
EC50 (4 days) 2.827 mg/L [2]
EC50 (72 h) 2.321 mg/L [2]
EC50 (48 h) 2.618 - 5.89 mg/L [6]
LC50 (7 days) 2.24 - 11.7 mg/L [4]
LC50 (4 days) 3.29 - 429 mg/L [6]

Type of Study provided
Studies with data
Key study 78
Supporting study 30
Weight of evidence
Other 72 2
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 47 studies submitted
  • 30 studies processed
P/RResults
NOEC (3.767 months) 334.3 µg/L [2]
NOEC (42 days) 712.9 µg/L [2]
NOEC (30 days) 16.5 - 684.3 µg/L [24]
NOEC (28 days) 6.83 - 3 730 µg/L [18]
NOEC (21 days) 60.8 - 93.3 µg/L [4]

Type of Study provided
Studies with data
Key study 30
Supporting study 12
Weight of evidence
Other 4 1
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 39 studies submitted
  • 11 studies processed
P/RResults
EC50 (7 days) 24.1 µg/L [2]
EC50 (4 days) 71.314 mg/L [2]
EC50 (72 h) 28.8 - 819.4 µg/L [34]
NOEC (7 days) 1.8 µg/L [2]
NOEC (4 days) 4.672 mg/L [4]

Type of Study provided
Studies with data
Key study 11
Supporting study 10
Weight of evidence
Other 17 1
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
EC50 for freshwater algae
197 - 310.4 µg/L
EC50 for marine water algae
24.1 µg/L
EC10 or NOEC for freshwater algae
66.9 - 76.4 µg/L
EC10 or NOEC for marine water algae
1.23 µg/L

Toxicity to aquatic plants other than algae

Study results
  • 18 studies submitted
  • 6 studies processed
P/RResults
EC50 (7 days) 19.29 - 565.3 µg/L [26]
NOEC (7 days) 3 - 32.9 µg/L [26]
LOEC (7 days) 8.24 - 67.9 µg/L [26]
EC10 (7 days) 4.79 - 62.17 µg/L [26]
EC20 (7 days) 8.28 - 108.12 µg/L [24]

Type of Study provided
Studies with data
Key study 6
Supporting study
Weight of evidence
Other 12
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
EC50 for freshwater plants
52 µg/L
EC10 or NOEC for freshwater plants
10.4 µg/L

Toxicity to microorganisms

Study results
  • 14 studies submitted
  • 2 studies processed
P/RResults
EC50 (30 min) 120 mg/L [2]
EC10 (30 min) 3.73 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 4
Weight of evidence
Other 6 2
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
EC50 for microorganisms
120 mg/L
EC10 or NOEC for microorganisms
3.73 mg/L

Sediment toxicity

Study results
  • 31 studies submitted
  • 22 studies processed
P/RResults
NOEC (42 days) 469 - 1 786.7 mg/kg sediment dw [12]
NOEC (28 days) 469 - 4 384 mg/kg sediment dw [24]
NOEC (28 days) 9.84 - 23.56 mg/L [12]
NOEC (10 days) 48.9 - 3 790 mg/kg sediment dw [78]
LOEC (42 days) 469 - 3 693.3 mg/kg sediment dw [12]

Type of Study provided
Studies with data
Key study 16
Supporting study
Weight of evidence 6
Other 9
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
EC50 / LC50 for freshwater sediment
1 703 mg/kg sediment dw
EC10 / LC10 or NOEC for freshwater sediment
698 mg/kg sediment dw

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 9 studies submitted
  • 6 studies processed
P/RResults
NOEC (42 days) 868 - 1 091 mg/kg soil dw [4]
NOEC (28 days) 163 mg/kg soil dw [2]
EC10 (42 days) 51.5 - 145.4 mg/kg soil dw [8]
EC10 (28 days) 54.8 - 426 mg/kg soil dw [18]

Type of Study provided
Studies with data
Key study 6
Supporting study
Weight of evidence
Other 1 2
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 9 studies submitted
  • 8 studies processed
P/RResults
EC10 (28 days) 14.3 - 754 mg/kg soil dw [24]
NOEC (28 days) 100 - 1 000 mg/kg soil dw [4]

Type of Study provided
Studies with data
Key study 4 4
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 31 studies submitted
  • 28 studies processed
P/RResults
NOEC (21 days) 9 - 34 mg/kg soil dw [6]
NOEC (4 days) 180 mg/kg soil dw [4]
EC10 (21 days) 8 - 617 mg/kg soil dw [78]
EC10 (14 days) 2.9 - 74.9 mg/kg soil dw [50]
EC10 (4 days) 13 - 255 mg/kg soil dw [20]

Type of Study provided
Studies with data
Key study 2 26
Supporting study 2
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 9 studies submitted
  • 6 studies processed
P/RResults
NOEC (28 days) 120 mg/kg soil dw [2]
NOEC (24 h) 80 mg/kg soil dw [2]
EC10 (28 days) 36 - 4 685 mg/kg soil dw [16]
EC10 (7 days) 22 - 695 mg/kg soil dw [18]
EC10 (24 h) 6 - 602 mg/kg soil dw [18]

Type of Study provided
Studies with data
Key study 6
Supporting study 2
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 9 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 6
Other 3
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Long-term EC10 / LC10 / NOEC
50 mg/kg food

Toxicity to mammals

Study results
  • 4 studies submitted
  • 4 studies processed
P/RResults
NOEC (3.733 months) 200 mg/kg diet [4]

Type of Study provided
Studies with data
Key study 4
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 3 summaries submitted
  • 3 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DMEL) -
Acute /short term: No hazard identified
Local Effects
Long-term: (DNEL) 80.7 µg/m³ repeated dose toxicity
Acute /short term: High hazard (no threshold derived)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: Medium hazard (no threshold derived)
Acute /short term: Medium hazard (no threshold derived)
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: (DNEL) 12.7 µg/m³ carcinogenicity
Acute /short term: High hazard (no threshold derived)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: Medium hazard (no threshold derived)
Acute /short term: Medium hazard (no threshold derived)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 60 µg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 106 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 8 3
Supporting study 85
Weight of evidence
Other 10
Data waiving
no waivers
Study data: dermal absorption
  • 10 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study 5
Supporting study 1
Weight of evidence
Other 4
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Bioaccumulation potential:
No bioaccumulation potential

Acute toxicity

Study results
oral
  • 5 studies submitted
  • 5 studies processed
P/RResults
LD50 434 - 732 mg/kg bw (rat) [9]
LD50 250 mg/kg bw (rabbit) [1]
M/CInterpretations of results
Category 4 based on GHS criteria [1]

Type of Study provided
oral
Studies with data
Key study 3 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 2 studies submitted
  • 2 studies processed
P/RResults
LC50 (4 h) 5.08 mg/L air (rat) [2]
M/CInterpretations of results
GHS criteria not met [1]

inhalation
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 8 studies submitted
  • 6 studies processed
P/RResults
LD50 2 000 mg/kg bw (rat) [6]
M/CInterpretations of results
Not classified [6]

dermal
Studies with data
Key study
Supporting study
Weight of evidence 6
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oral route:
Adverse effect observed LD50 697 mg/kg bw
Inhalation route:
No adverse effect observed LC50 5.08 mg/L air

Irritation / corrosion

Study results
Study data: skin
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: eye
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 2 summaries processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)

Sensitisation

Study results
Study data: skin
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 4
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Skin sensitisation
Adverse effect observed (sensitising)
Respiratory sensitisation
Adverse effect observed (sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 38 studies submitted
  • 2 studies processed
P/RResults
NOAEL (rat): 3 mg/kg bw/day [2]

Type of Study provided
Study data: oral
Studies with data
Key study 2
Supporting study 6
Weight of evidence
Other 30
Data waiving
no waivers
Study data: inhalation
  • 26 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study
Supporting study 20
Weight of evidence
Other 6
Data waiving
no waivers
Study data: dermal
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Genetic toxicity

Study results
Study data: in vitro
  • 103 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 3
Supporting study
Weight of evidence 82
Other 18
Data waiving
no waivers
Study data: in vivo
  • 33 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 1
Supporting study 2
Weight of evidence 24
Other 4 2
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 11 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 8 2
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 32 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 4
Supporting study
Weight of evidence
Other 22 4
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: developmental
  • 31 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 4 1
Supporting study
Weight of evidence
Other 26
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant