Brief Profile

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Please be aware that the REACH registration parts of this Brief Profile are no longer maintained; they remain frozen as of 19th May 2023. All other data parts (substance identity, C&L, key regulatory lists etc. are up to date).

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
415-430-8
CAS no.:
86403-32-9
Index number:
607-383-00-9
Molecular formula:
SMILES:
InChI:
Type of substance:
Multi constituent substance
Origin:
Organic
Registered compositions:
15
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
ELINCS (European LIst of Notified Chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance is very toxic to aquatic life, is very toxic to aquatic life with long lasting effects, causes serious eye damage and may cause an allergic skin reaction.

Breakdown of all 116 C&L notifications submitted to ECHA

Aquatic Acute 1 H400 Harmonised Classification
Aquatic Chronic 1 H410 Harmonised Classification
Eye Dam. 1 H318 Harmonised Classification
Skin Sens. 1 H317 Harmonised Classification
Skin Sens. 1A H317
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • Ss
Officially recognised in the EU as Skin sensitising ( Harmonised C&L).
  • Ss
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Skin sensitising (25% of REACH registrations).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 13 active registrations under REACH, 3 Joint Submission(s) and 3 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Industrial accident prevention and reporting requirements have been established for this substance.
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: lubricants and greases.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles, high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding) and production of mixtures or articles by tabletting, compression, extrusion or pelletisation.

Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance can be found in products with material based on: plastic (e.g. food packaging and storage, toys, mobile phones), plastic used for large surface area articles (e.g. construction and building materials for flooring, insulation) and rubber (e.g. tyres, shoes, toys).

This substance is used in the following products: lubricants and greases and polymers.

This substance is used for the manufacture of: rubber products.

This substance is used in the following activities or processes at workplace: closed processes with no likelihood of exposure, transfer of chemicals, closed, continuous processes with occasional controlled exposure and heat / pressure transfer fluids in closed systems.

Release to the environment of this substance can occur from industrial use: as processing aid. Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

This substance is used in the following products: polymers.

This substance is used in the following activities or processes at workplace: transfer of chemicals, transfer of substance into small containers, closed batch processing in synthesis or formulation, production of mixtures or articles by tabletting, compression, extrusion or pelletisation, closed, continuous processes with occasional controlled exposure, mixing in open batch processes, closed processes with no likelihood of exposure and laboratory work.

Release to the environment of this substance can occur from industrial use: formulation in materials.

This substance is used in the following products: polymers and coating products.

This substance is used for the manufacture of: and plastic products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, production of mixtures or articles by tabletting, compression, extrusion or pelletisation, mixing in open batch processes, the low energy manipulation of substances bound in materials or articles, high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding), closed, continuous processes with occasional controlled exposure and closed batch processing in synthesis or formulation.

Release to the environment of this substance can occur from industrial use: in the production of articles.

This substance is used in the following activities or processes at workplace: closed batch processing in synthesis or formulation, closed processes with no likelihood of exposure, transfer of chemicals at dedicated facilities and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

General statements

Keep out of reach of children.

Prevention statements

When handling this substance: avoid release to the environment; do not get in eyes, on skin, or on clothing; avoid breathing the dust, fume, gas, mist, vapours or spray; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. If exposed or concerned: get medical advice/attention. Immediately call a poison center or doctor/physician. If skin irritation or a rash occurs: get medical advice/attention. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing. If on skin: wash with soap and water.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • ADEKA POLYMER ADDITIVES EUROPE SAS, 13 rue du 17 Novembre FR-68100 MULHOUSE France
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Chemko, a.s. Slovakia, Mlynske nivy 10 82109 Bratislava Slovakia
  • Clariant Plastics & Coatings (Deutschland) GmbH, August-Laubenheimer-Straße 1 Global Product Stewardship 65929 Frankfurt am Main Germany
  • Clariant Production (France) S.A.S., 21-23 rue du Petit Albi Bâtiment Le Cérès, Hall 303, CS 18545 95892 CergyCergy Pontoise Cedex France
  • Cytec Industries BV, Weena 505 3013 AL Rotterdam Netherlands
  • Evonik Operations GmbH, Rellinghauser Straße 1-11 45128 Essen Germany
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland
  • REACH24H CONSULTING GROUP (acts as OR for Fujian Disheng Technology Co.,Ltd.), Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
  • REACH24H CONSULTING GROUP (acts as the OR for SUQIAN UNITECH CORP., LTD), Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
  • Rianlon GmbH, Charlottenstr. 75 40210 Duesseldorf Germany
  • Sabo GmbH, Paul-Baumann-Straße 1 45772 Marl Germany
  • SABO SPA, Via Caravaggi 24040 Levate Bergamo Italy
  • Chemservice S.A. (8LF5), 13, Fausermillen 6689 Mertert Luxembourg
  • Clariant SE - CN29, Brueningstrasse 50 65929 Frankfurt am Main Germany
  • Evonik Operations GmbH - E04, Rellinghauser Strasse 1-11 45128 Essen Germany
  • Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority., null
  • Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority., null
  • Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority., null

Substance names and other identifiers

A mixture of: 2,2,6,6-tetramethylpiperidin-4-yl-hexadecanoate; 2,2,6,6-tetramethylpiperidin-4-yl-octadecanoate
EC Inventory, Other
A mixture of: 2,2,6,6-tetramethylpiperidin-4-yl-hexadecanoate; 2,2,6,6-tetramethylpiperidin-4-yl-octadecanoate
CYASORB UV-3853 LIGHT STABILIZER; DASTIB 845; SANDUVOR 845
REACH pre-registration, Other
Fatty acids, C15-18, tetramethylpiperidinyl esters
CYASORB UV-3853 LIGHT STABILIZER; DASTIB 845; SANDUVOR 845
Other
reaction mass of: 2,2,6,6-tetramethylpiperidin-4-yl-hexadecanoate 2,2,6,6-tetramethylpiperidin-4-yl-octadecanoate
CYASORB UV-3853 LIGHT STABILIZER; DASTIB 845; SANDUVOR 845
C&L Inventory
reaction mass of: 2,2,6,6-tetramethylpiperidin-4-yl-hexadecanoate; 2,2,6,6-tetramethylpiperidin-4-yl-octadecanoate
CYASORB UV-3853 LIGHT STABILIZER; DASTIB 845; SANDUVOR 845
CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
2,2,6,6-tetrametilpiperidin-4-il-hexadekanoát 2,2,6,6-tetrametilpiperidin-4-il-oktadekanoát keveréke (hu)
C&L Inventory
2,2,6,6-tetrametilpiperidīn-4-il-heksadekanoāta un 2,2,6,6-tetrametilpiperidīn-4-il-oktadekanoāta maisījums (lv)
C&L Inventory
Blanding af: 2,2,6,6-tetramethylpiperidin-4-yl-hexadecanoat 2,2,6,6-tetramethylpiperidin-4-yl-octadecanoat (da)
C&L Inventory
blanding av: 2,2,6,6-tetrametylpiperidin-4-ylheksadecanoat 2,2,6,6-tetrametylpiperidin-4-yloktadecanoat (no)
C&L Inventory
Blandning av: 2,2,6,6-tetrametylpiperidin-4-ylhexadekanoat 2,2,6,6-tetramethylpiperidin-4-yloktadekanoat (sv)
C&L Inventory
masa de reactie a : 2,2,6,6-tetrametilpiperidin-4-il-hexadecanoat 2,2,6,6-tetrametilpiperidin-4-il-octadecanoat (ro)
C&L Inventory
masse de réaction de: 2,2,6,6-tétraméthylpipéridin-4-yl-hexadécanoate; 2,2,6,6-tétraméthylpipéridin-4-yl-octadécanoate octadécanoate de 2,2,6,6-tétraméthylpipéridin-4-yle (fr)
C&L Inventory
Mengsel van: 2,2,6,6-tetramethylpiperidin-4-yl-hexadecanoaat 2,2,6,6-tetramethylpiperidin-4-yl-octadecanoaat (nl)
C&L Inventory
Mezcla de: hexadecanoato de 2,2,6,6-tetrametilpiperidin-4-ilo octadecanoato de 2,2,6,6-tetrametilpiperidin-4-ilo (es)
C&L Inventory
mieszanina poreakcyjna: heksadekanian 2,2,6,6-tetrametylopiperydyn-4-ylu oktadekanian 2,2,6,6-tetrametylopiperydyn-4-ylu (pl)
C&L Inventory
Miscela di: esadecanoato di 2,2,6,6-tetrametilpiperidin-4-ile ottadecanoato di 2,2,6,6-tetrametilpiperidin-4-ile (it)
C&L Inventory
Mistura de: hexadecanoato de 2,2,6,6-tetrametilpiperidin-4-ilo octadecanoato de 2,2,6,6-tetrametilpiperidin-4-ilo (pt)
C&L Inventory
mišinys: 2,2,6,6-tetrametilpiperidin-4-il-heksadekanoato 2,2,6,6-tetrametilpiperidin-4-il-oktadekanoato (lt)
C&L Inventory
Reaction mass aus: 2,2,6,6-Tetramethylpiperidin-4-yl-hexadecanoat und 2,2,6,6-Tetramethylpiperidin-4-yl-octadecanoat (de)
C&L Inventory
reakcijska smjesa: 2,2,6,6-tetrametil-piperidin-4-il-heksadekanoata 2,2,6,6-tetrametil-piperidin-4-il-oktadekanoata (hr)
C&L Inventory
reakčná zmes zložená z týchto látok: (2,2,6,6-tetrametylpiperidín-4-yl)-hexadekanoát (2,2,6,6-tetrametylpiperidín-4-yl)-oktadekanoát (sk)
C&L Inventory
reakční směs: 2,2,6,6-tetramethylpiperidin-4-yl-hexadekanoát 2,2,6,6-tetramethylpiperidin-4-yl-oktadekanoát (cs)
C&L Inventory
Segu: 2,2,6,6-tetrametüülpiperidiin-4-üülheksadekanoaat 2,2,6,6-tetrametüülpiperidiin-4-üüloktadekanoaat (et)
C&L Inventory
Seos: 2,2,6,6-tetrametyylipiperidin-4-yyliheksadekanoaatti 2,2,6,6-tetrametyylipiperidin-4-yylioktadekanoaatti (fi)
C&L Inventory
реакционна маса от: 2,2,6,6-тетраметилпиперидин-4-ил- хексадеканоат 2,2,6,6-тетраметилпиперидин-4-ил-октадеканоат (bg)
C&L Inventory
2,2,6,6-tetramethylpiperidin-4-yl hexadecanoate 2,2,6,6-tetramethylpiperidin-4-yl octadecanoate
Other
A mixture of: 2,2,6,6-tetramethylpiperidin-4-yl-hexadecanoate; 2,2,6,6-tetramethylpiperidin-4-yl-octadecanoate
C&L Inventory
A mixture of: 2,2,6,6-tetramethylpiperidin-4-yl-hexadecanoate; 2,2,6,6-tetramethylpiperidin-4-yl-octadecanoate
Registration dossier
CPSS 53
Registration dossier
CPSS53
Registration dossier
CYASORB UV-3853 LIGHT STABILIZER
Registration dossier
Dastib 845
Registration dossier
Fatty acids, C15-18, tetramethylpiperidinyl esters
C&L Inventory
Hostavin N 28
Registration dossier
HS-436
Registration dossier
Reaction mass of 2,2,6,6-tetramethylpiperidin-4-yl hexadecanoate and 2,2,6,6-tetramethylpiperidin-4-yl octadecanoate
Registration dossier
Reaction mass of 2,2,6,6-tetramethylpiperidin-4-yl-hexadecanoate and 2,2,6,6-tetramethylpiperidin-4-yl-octadecanoate
Registration dossier
Reaction mass of hexadecanoic acid, 2,2,6,6-tetramethyl-4-piperidinyl ester and octadecanoic acid, 2,2,6,6-tetramethyl-4-piperidinyl ester
Registration dossier
reaction mass of: 2,2,6,6-tetramethylpiperid-4-yl-hexadecanoate 2,2,6,6-tetramethylpiperid-4-yl-octadecanoate
Registration dossier
2,2,6,6-Tetramethyl-4-piperidinyl stearate
Registration dossier
4-piperidol,2,2,6,6-tetramethyl- RPW stearin (fatty acids mixture)
Registration dossier
CYASORB UV-3853 LIGHT STABILIZER
Registration dossier
DASTIB 845
Registration dossier
Hostavin N 28
Registration dossier
HS-436
Registration dossier
SANDUVOR 845
Registration dossier
SONGLIGHT 3853
Registration dossier
SONGLIGHT 3853 SD
Registration dossier
UV-3853
Registration dossier
607-383-00-9
Index number
C&L Inventory
86403-32-9
CAS number
C&L Inventory, Registration dossier, Other, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 12 studies submitted
  • 5 studies processed
C Physical state at 20°C and 1013 hPa
Solid (100%) [5]
C Form
Other (100%) [5]
C Odour
Odourless (100%) [2]
C Substance type
Organic (100%) [2]

Type of Study provided
Studies with data
Key study 4 3
Supporting study
Weight of evidence
Other 5
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Physical state at 20°C and 1013 hPa
Solid (100%)

Melting/freezing point

Study results
  • 11 studies submitted
  • 7 studies processed
R Melting / freezing point
29.6 - 30 °C @ 1.013 - 1 013.25 hPa [7]

Type of Study provided
Studies with data
Key study 8
Supporting study
Weight of evidence
Other 3
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Melting / freezing point at 101 325 Pa
29.6 °C

Boiling point

Study results
  • 12 studies submitted
  • 8 studies processed
R Boiling point
246 - 319 °C @ 39 - 101.3 kPa [8]

Type of Study provided
Studies with data
Key study 9
Supporting study
Weight of evidence
Other 3
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 1 summary processed
Boiling point at 101 325 Pa
301 °C

Density

Study results
  • 12 studies submitted
  • 8 studies processed
R Relative density
0.955 - 0.96 @ 20 °C [8]

Type of Study provided
Studies with data
Key study 9
Supporting study
Weight of evidence
Other 3
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Relative density at 20°C
0.96

Vapour pressure

Study results
  • 11 studies submitted
  • 7 studies processed
R Vapour pressure
0.037 - 0.26 Pa @ 20 - 50 °C [14]

Type of Study provided
Studies with data
Key study 8
Supporting study
Weight of evidence
Other 3
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Vapour pressure
0.037 Pa @ 20 °C

Partition coefficient

Study results
  • 12 studies submitted
  • 7 studies processed
R Log Pow
6.5 - 8.92 @ 7 - 40 °C and pH 7 [7]

Type of Study provided
Studies with data
Key study 4 3
Supporting study 1
Weight of evidence
Other 3
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Log Kow (Log Pow)
6.5 - 9.81 @ 25 - 40 °C

Water solubility

Study results
  • 13 studies submitted
  • 7 studies processed
R Water solubility (mass/vol.)
500 µg/L @ 20 °C and pH 7.5 [7]

Type of Study provided
Studies with data
Key study 8
Supporting study 2
Weight of evidence
Other 3
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Water solubility
500 µg/L @ 20 °C

Solubility in organic solvents / fat solubility

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Surface tension

Study results
  • 10 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 3
Data waiving
Not feasible 3
Sci. unjustified 2
Exposure cons.
Other 2
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 11 studies submitted
  • 6 studies processed
R Flash point
140 °C @ 101.325 kPa [6]

Type of Study provided
Studies with data
Key study 7
Supporting study
Weight of evidence
Other 3
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
R Summaries
  • 2 summaries submitted
  • 1 summary processed
Flash point at 101 325 Pa
140 °C

Auto flammability

Study results
  • 11 studies submitted
  • 3 studies processed
R Autoflammability / self-ignition
350 °C @ 101.325 kPa [3]

Type of Study provided
Studies with data
Key study 7
Supporting study
Weight of evidence
Other 3
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 14 studies submitted
  • 3 studies processed
C Interpretation of results
Non flammable (100%) [3]

Type of Study provided
Studies with data
Key study 8
Supporting study 1
Weight of evidence
Other 3
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Flammability
Non flammable (100%)

Explosiveness

Study results
  • 10 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 3
Data waiving
Not feasible 2
Sci. unjustified 2
Exposure cons.
Other 3
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 10 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 3
Data waiving
Not feasible 2
Sci. unjustified 3
Exposure cons.
Other 2
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 5 studies submitted
  • 2 studies processed
R Other:
166 000 [1]
R dynamic viscosity (in mPa s)
6.8 - 24.9 [5]

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other 1
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 12 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 6
Supporting study 2
Weight of evidence
Other 3
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 20 studies submitted
  • 1 study processed
R COD
3 g O2/g test material [1]

Type of Study provided
Studies with data
Key study 11
Supporting study 2
Weight of evidence
Other 7
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 1 summary processed
Biodegradation in water
Under test conditions no biodegradation observed (100%)

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons. 1
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons. 1
Other
R Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation Factor (BCF) - dimensionless
142.2

Bioaccumulation: terrestrial

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Adsorption/desorption

Study results
  • 7 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 1
Data waiving
Not feasible 2
Sci. unjustified 2
Exposure cons.
Other
R Summaries
  • 2 summaries submitted
  • 1 summary processed
Koc at 20°C
1 746 000

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 3 summaries submitted
  • 3 summaries processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 100 - 1 080 ng/L (3)
Intermittent releases (freshwater) 1 - 1.07 µg/L (3)
Marine water 10 - 108 ng/L (3)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 10 - 63.6 mg/L (3)
Sediment (freshwater) 4.263 - 189 mg/kg sediment dw (3)
Sediment (marine water) 426 - 18 900 µg/kg sediment dw (3)
Hazard for Air
Air No hazard identified (2)
Hazard for Terrestrial Organism
Soil 502 - 37 700 µg/kg soil dw (3)
Hazard for Predators
Secondary poisoning 1.33 mg/kg food (1)

Short–term toxicity to fish

Study results
  • 14 studies submitted
  • 7 studies processed
P/RResults
LC50 (4 days) 140 - 800 µg/L [3]
NOEC (4 days) 140 - 800 µg/L [7]

Type of Study provided
Studies with data
Key study 8
Supporting study
Weight of evidence
Other 6
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Short–term toxicity to aquatic invertebrates

Study results
  • 11 studies submitted
  • 7 studies processed
P/RResults
EC50 (48 h) 100 - 106.8 µg/L [7]
EC50 (24 h) 100 - 106.8 µg/L [6]
LC50 (24 h) 106.8 µg/L [1]
EC100 (48 h) 500 µg/L [3]
NOEC (48 h) 20 - 22.8 µg/L [6]

Type of Study provided
Studies with data
Key study 8
Supporting study
Weight of evidence
Other 3
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 3 studies submitted
  • 2 studies processed
P/RResults
NOEC (21 days) 54 µg/L [2]
LOEC (21 days) 81 µg/L [2]
EC50 (21 days) 190 µg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 15 studies submitted
  • 8 studies processed
P/RResults
EC50 (72 h) 495 - 100 000 µg/L [10]
NOEC (72 h) 495 - 100 000 µg/L [12]
NOELR (72 h) 100 mg/L [1]

Type of Study provided
Studies with data
Key study 7
Supporting study
Weight of evidence 1 1
Other 1 5
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
EC50 for freshwater algae
495 µg/L
EC10 or NOEC for freshwater algae
495 - 100 000 µg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 8 studies submitted
  • 4 studies processed
P/RResults
EC50 (3 h) 1 g/L [1]
IC50 (3 h) 1 g/L [2]
NOEC (3 h) 636 mg/L [3]
EC0 (28 days) 100 mg/L [1]

Type of Study provided
Studies with data
Key study 4
Supporting study
Weight of evidence
Other 3
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
EC50 for microorganisms
100 mg/L
EC10 or NOEC for microorganisms
636 mg/L

Sediment toxicity

Data not provided by the registrant

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons. 1
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons. 1
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons. 1
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons. 2
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Data not provided by the registrant

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 3 summaries submitted
  • 3 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 2.5 mg/m³ repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 266 µg/kg bw/day repeated dose toxicity
Acute /short term: No DNEL required: short term exposure controlled by conditions for long-term
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
High hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 620 µg/m³ repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 180 µg/kg bw/day repeated dose toxicity
Acute /short term: No DNEL required: short term exposure controlled by conditions for long-term
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 70 µg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
EYE Exposure
High hazard (no threshold derived)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 1 2
Supporting study
Weight of evidence
Other 3
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Bioaccumulation potential:
Low bioaccumulation potential
Absorption values
Oral: 80 %
Dermal: 30 %
Inhalation: 30 %

Acute toxicity

Study results
oral
  • 16 studies submitted
  • 9 studies processed
P/RResults
LD50 10 000 - 15 000 mg/kg bw (rat) [4]
LD50 10 000 mg/kg bw (mouse) [1]
M/CInterpretations of results
GHS criteria not met [2]

Type of Study provided
oral
Studies with data
Key study 11
Supporting study 1
Weight of evidence
Other 4
Data waiving
no waivers
inhalation
  • 7 studies submitted
  • 5 studies processed
P/RResults
LC50 (7 h) 5 mg/m³ air (rat) [3]
LC0 (7 h) 5 mg/m³ air (rat) [2]
M/CInterpretations of results
GHS criteria not met [1]

inhalation
Studies with data
Key study 5
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
dermal
  • 10 studies submitted
  • 6 studies processed
P/RResults
LD50 5 000 mg/kg bw (rat) [4]
M/CInterpretations of results
GHS criteria not met [1]

dermal
Studies with data
Key study 7
Supporting study
Weight of evidence
Other 3
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Oral route:
No adverse effect observed LD50 10 000 mg/kg bw
Dermal route:
No adverse effect observed Discriminating dose 5 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 13 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 8
Supporting study
Weight of evidence
Other 3
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Study data: eye
  • 13 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 8
Supporting study
Weight of evidence
Other 3
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin
No adverse effect observed (not irritating)
Eye
Adverse effect observed (irritating)
Respiratory
No adverse effect observed (not irritating)

Sensitisation

Study results
Study data: skin
  • 14 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 9
Supporting study
Weight of evidence
Other 3
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin sensitisation
Adverse effect observed (sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 13 studies submitted
  • 5 studies processed
P/RResults
NOAEL (rat): 40 mg/kg bw/day [2]
NOAEL (other:): 40 mg/kg bw/day [3]
NOEL (rat): 40 mg/kg bw/day [2]
NOEL (other:): 40 mg/kg bw/day [2]

Type of Study provided
Study data: oral
Studies with data
Key study 6
Supporting study 3
Weight of evidence
Other 3
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: inhalation
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Study data: dermal
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Oral route - systemic effects:
No adverse effect observed NOAEL 40 mg/kg bw/day (subacute, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 24 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 17
Supporting study 1
Weight of evidence
Other 6
Data waiving
no waivers
Study data: in vivo
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Toxicity - InVitro
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: developmental
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant