Summary of Classification and Labelling
Harmonised classification - Annex VI of Regulation (EC) No 1272/2008 (CLP Regulation)
General Information
ATP Inserted / Updated: CLP00 ![]() CLP Classification (Table 3)
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Seveso III Data
Disclaimer: Please note that some of the substances covered by the Seveso Directive can belong to more than one Seveso categories. It will be up to the users to decide whether their substance or mixture fall in one or in more of these classification categories depending on the tonnage bands and the concentrations.
Please also note that ECHA is not an authority for the Seveso Directive and that the Seveso categorisation below is provided for information only. The Seveso III Directive (Directive 2012/18/EU repealing Directive 96/82/EC (Seveso II) from 1 June 2015) is the only authentic legal reference and that the information in this inventory does not constitute legal advice. For further information on Seveso, please ask your national authority.
Please also note that ECHA is not an authority for the Seveso Directive and that the Seveso categorisation below is provided for information only. The Seveso III Directive (Directive 2012/18/EU repealing Directive 96/82/EC (Seveso II) from 1 June 2015) is the only authentic legal reference and that the information in this inventory does not constitute legal advice. For further information on Seveso, please ask your national authority.
Seveso Data | |
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Seveso Substance | Seveso Categories |
Igen |
H2
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Notified classification and labelling
General Information
EC / List no.
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Name |
CAS Number
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225-863-2 | 4,4'-methylenedicyclohexyl diisocyanate | 5124-30-1 |
Notified classification and labelling according to CLP criteria
Classification | Labelling | Specific Concentration limits, M-Factors | Notes | Classification affected by Impurities / Additives
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Additional Notified Information
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Number of Notifiers
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Joint Entries
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Hazard Class and Category Code(s) | Hazard Statement Code(s) | Hazard Statement Code(s) | Supplementary Hazard Statement Code(s) | Pictograms, Signal Word Code(s) | |||||||
Skin Irrit. 2 | H315 | H315 |
GHS08 GHS06 Dgr |
7546; : C ≥ .5 % Resp. Sens. 1; : C ≥ .5 % |
State/Form
|
18 | ![]() |
View details | |||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 2 | H330 | H330 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 (other:respirato...) | H335 | |||||||||
Skin Irrit. 2 | H315 | H315 |
GHS08 GHS06 Dgr |
Resp. Sens. 1; : C ≥ .5 % 7546; : C ≥ .5 % |
State/Form
|
18 | ![]() |
View details | |||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 3 | H331 | H331 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 (other:respirato...) | H335 | |||||||||
Skin Irrit. 2 | H315 | H315 |
GHS08 GHS06 Dgr |
7546; : C ≥ .5 % Resp. Sens. 1; : C ≥ .5 % |
Note 2
|
State/Form
|
273 | View details | |||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 3 | H331 | H331 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 | H335 | |||||||||
Skin Irrit. 2 | H315 | H315 |
GHS08 GHS06 Dgr |
7546; : C ≥ .5 % Resp. Sens. 1; : C ≥ .5 % |
Note 2
|
State/Form
|
232 | View details | |||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 3 | H331 | H331 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 | H335 | |||||||||
STOT SE 3 | H335 (other:-) | H335 | |||||||||
Skin Irrit. 2 | H315 | H315 |
GHS08 GHS06 Dgr |
Resp. Sens. 1; : C ≥ .5 % 7546; : C ≥ .5 % |
Note 2
|
State/Form
|
87 | View details | |||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 2 | H330 | H330 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 (other:-) | H335 | |||||||||
Skin Irrit. 2 | H315 | H315 |
GHS08 GHS06 Dgr |
Resp. Sens. 1; : C ≥ .5 % 7546; : C ≥ .5 % |
Note 2
|
State/Form
|
71 | View details | |||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 2 | H330 | H330 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 (not known) | H335 | |||||||||
Skin Irrit. 2 | H315 | H315 |
GHS08 Dgr |
59 | View details | ||||||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 3 | H331 | H331 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 (other:Not provi...) | H335 | |||||||||
STOT SE 3 | H335 (Not provided) | H335 | |||||||||
Skin Irrit. 2 | H315 | H315 |
GHS08 GHS06 Dgr |
7546; : C ≥ .5 % Resp. Sens. 1; : C ≥ .5 % |
State/Form
|
51 | View details | ||||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 3 | H331 | H331 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 | H335 | |||||||||
Not Classified | 37 | ||||||||||
Skin Irrit. 2 | H315 | H315 |
GHS08 GHS06 Dgr |
7546; : C ≥ .5 % Resp. Sens. 1; : C ≥ .5 % |
Note 2
|
37 | View details | ||||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 2 | H330 | H330 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 (-Atmungssystem) | H335 | |||||||||
Skin Irrit. 2 | H315 | H315 |
GHS08 GHS06 Dgr |
7546; : C ≥ .5 % Resp. Sens. 1; : C ≥ .5 % |
State/Form
|
33 | View details | ||||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 3 | H331 | H331 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 (not specified) | H335 | |||||||||
Acute Tox. 4 | H302 | H302 |
GHS08 GHS06 Dgr |
Resp. Sens. 1; : C ≥ .5 % 7546; : C ≥ .5 % |
28 | View details | |||||
Skin Irrit. 2 | H315 | H315 | |||||||||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 1 | H330 | H330 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 (other:Respirato...) | H335 | |||||||||
Skin Irrit. 2 | H315 | H315 |
GHS08 GHS06 Dgr |
Resp. Sens. 1; : C ≥ .5 % 7546; : C ≥ .5 % |
Note 2
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State/Form
|
21 | View details | |||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 2 | H330 | H330 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 | H335 | |||||||||
Skin Irrit. 2 | H315 | H315 |
GHS08 GHS06 Dgr |
State/Form
|
10 | View details | |||||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 3 | H331 | H331 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 (not identified) | H335 | |||||||||
STOT SE 3 | H335 (other:not ident...) | H335 | |||||||||
Skin Irrit. 2 | H315 | H315 |
GHS08 GHS06 Dgr |
7546; : C ≥ .5 % Resp. Sens. 1; : C ≥ .5 % |
7 | View details | |||||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 3 | H331 | H331 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 | H335 | |||||||||
STOT SE 3 | H335 (other:-) | H335 | |||||||||
Skin Irrit. 2 | H315 | H315 |
GHS08 GHS06 Dgr |
Resp. Sens. 1; : C ≥ .5 % 7546; : C ≥ .5 % |
Note 2
|
State/Form
|
7 | View details | |||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 3 | H331 | H331 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 (other:-) | H335 | |||||||||
Skin Irrit. 2 | H315 | H315 (H315) |
GHS08 GHS06 Dgr |
Note 2
|
5 | View details | |||||
Skin Sens. 1 | H317 | H317 (H317) | |||||||||
Eye Irrit. 2 | H319 | H319 (H319) | |||||||||
Acute Tox. 3 | H331 | H331 (H331) | |||||||||
Resp. Sens. 1 | H334 | H334 (H334) | |||||||||
STOT SE 3 | H335 (other:eyes, res...) | H335 (H335) | |||||||||
STOT SE 3 | H335 (eyes, respirato...) | H335 (H335) | |||||||||
Skin Irrit. 2 | H315 | H315 |
GHS08 GHS06 Dgr |
Resp. Sens. 1; : C ≥ .5 % 7546; : C ≥ .5 % |
2 | View details | |||||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 3 | H331 | H331 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 (Respiratory Sys...) | H335 | |||||||||
Skin Irrit. 2 | H315 | H315 | EUH204 |
GHS08 GHS06 Dgr |
State/Form
|
2 | View details | ||||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 3 | H331 | H331 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 (other:Lung) | H335 | |||||||||
STOT SE 3 | H335 (Lung) | H335 | |||||||||
Skin Irrit. 2 | H315 | H315 |
GHS08 GHS06 Dgr |
7546; : .5 % ≤ C < 100 % Resp. Sens. 1; : .5 % ≤ C < 100 % |
Note 2
|
2 | View details | ||||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 2 | H330 | H330 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
Skin Irrit. 2 | H315 | H315 |
GHS07 GHS08 GHS06 Dgr |
Resp. Sens. 1; : C ≥ .5 % 7546; : C ≥ .5 % |
Note 2
|
2 | View details | ||||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 2 | H330 | H330 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 (other:-) | H335 | |||||||||
Skin Irrit. 2 | H315 | H315 |
GHS08 GHS06 Dgr |
State/Form
|
1 | View details | |||||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 3 | H331 | H331 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 (other:organs) | H335 | |||||||||
STOT SE 3 | H335 (organs) | H335 | |||||||||
Skin Irrit. 2 | H315 | H315 |
GHS08 GHS06 Dgr |
State/Form
|
1 | View details | |||||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 2 | H330 | H330 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 (not identified) | H335 | |||||||||
STOT SE 3 | H335 (other:not ident...) | H335 | |||||||||
Skin Irrit. 2 | H315 | H315 |
GHS07 GHS08 GHS06 Dgr |
1 | View details | ||||||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 2 | H330 | H330 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 (RESPIRATORY TRA...) | H335 | |||||||||
STOT SE 3 | H335 (other:RESPIRATO...) | H335 | |||||||||
Skin Irrit. 2 | H315 | H315 |
GHS08 GHS06 Dgr |
Note 2
|
State/Form
|
1 | View details | ||||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 3 | H331 | H331 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 (No data) | H335 | |||||||||
Skin Irrit. 2 | H315 | H315 |
GHS08 GHS09 GHS06 Dgr |
7546; : C ≥ .5 % Resp. Sens. 1; : C ≥ .5 % |
Note 2
|
State/Form
|
1 | View details | |||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 2 | H330 | H330 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 | H335 | |||||||||
Aquatic Chronic 2 | H411 | H411 | |||||||||
Skin Irrit. 2 | H315 | H315 |
GHS08 GHS06 Dgr |
7546; : C ≥ .5 % Resp. Sens. 1; : C ≥ .5 % |
Note 2
|
State/Form
|
1 | View details | |||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 3 | H331 | H331 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
H335 | |||||||||||
Skin Irrit. 2 | H315 | H315 | EUH204 |
GHS08 GHS07 GHS06 Dgr |
1 | View details | |||||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 3 | H331 | H331 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 (not specified) | H335 | |||||||||
STOT SE 3 | H335 (Not Specified) | H335 | |||||||||
Skin Irrit. 2 | H315 | H315 |
GHS08 GHS06 Dgr |
Resp. Sens. 1; : C ≥ .5 % 7546; : C ≥ .5 % |
Note 2
|
State/Form
|
1 | View details | |||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 3 | H331 | H331 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 (mouth, pharynx,...) | H335 | |||||||||
STOT SE 3 | H335 (other:mouth, ph...) | H335 | |||||||||
Skin Irrit. 2 | H315 | H315 |
GHS08 GHS06 Dgr |
State/Form
|
1 | View details | |||||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 3 | H331 | H331 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
H335 | |||||||||||
Skin Irrit. 2 | H315 | H315 |
GHS08 GHS06 Dgr |
Resp. Sens. 1; : C ≥ .5 % 7546; : C ≥ .5 % |
1 | View details | |||||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 2 | H330 | H330 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 | H335 | |||||||||
Skin Irrit. 2 | H315 | H315 |
GHS08 GHS07 GHS06 Dgr |
7546; : C ≥ .5 % Resp. Sens. 1; : C ≥ .5 % |
Note 2
|
1 | View details | ||||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 2 | H330 | H330 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 | H335 | |||||||||
Skin Irrit. 2 | H315 | H315 |
GHS08 GHS06 Dgr |
State/Form
|
1 | View details | |||||
Skin Sens. 1 | H317 | H317 | |||||||||
Eye Irrit. 2 | H319 | H319 | |||||||||
Acute Tox. 3 | H331 | H331 | |||||||||
Resp. Sens. 1 | H334 | H334 | |||||||||
STOT SE 3 | H335 (Central System) | H335 |
Number of Aggregated Notifications: 33