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EC number: 200-240-8 | CAS number: 55-63-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- November 1987-March 1991
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Meets National standards method with acceptable resctrictions.
- Qualifier:
- according to guideline
- Guideline:
- other: ASTM Designation E 729-80 (ASTM, 1980)
- GLP compliance:
- not specified
- Analytical monitoring:
- yes
- Details on sampling:
- - The stability of the NG stock solution were periodically checked during storage to assure that no decomposition occured. Standard solutions of NG were prepared by dilution of the stock solution freshly prepared each day of analysis. Standard solutions with concentrations of 10.0, 5.0, 2.5, and 1.0 µl/L were used.- Aqueous samples from bioassays were injected directly into HPLC after filtration to remove particles > 0,45 µm.In the cases where samples could not be analysed immediately following filtration, the filtered samples were stored at 4°C in amber glass vials fitted with Teflon-lined caps and analyzedwithin 24 h from the time the samples were originally taken from the test aquaria.
- Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION - Basic solution (the shipment): 1 g NG dissolved in JHU/APL well water. NG solutions were keep in the dark at 4°C in glass bottles.- NG stock solutions were prepared by adding appropriate amounts of the material to aerated JHU/APL well water and stirred for 4 to 8 h. No NG stock solutions were heated during preparation or filtering at 0.45 µm. All stock solutions were prepared in amber glass containers.
- Test organisms (species):
- Ceriodaphnia dubia
- Details on test organisms:
- TEST ORGANISM- Common name:Cladoceran- Source: The Center for Lake Superior Environmental Studies, University of Wisconsin-Superior- Age at study initiation (mean and range, SD): neonate (< 6 h)- Feeding during test- Food type: mixture of Cerophyl® (Cerophyl Laboratories, Inc. Kansas CIty, MO) and the green alga Selenastrum capricornutum, added to the daphnid culture to achieve final concentrations of 120 µg Cerophyl®/mL and Selenastrum capricornutum 6.7 x 100000 cells/mL.- Frequency: at the beginning of the test and at the 24-h renewal period during the testACCLIMATION- Acclimation conditions: 16-h light:8-h dark photoperiod (fluorescent lights, 60-85 foot candles at the surface of the culture vessels).- The stock culture was maintained in 600 m glass beakers, containing 400 m of JHU/APL deep well water, enriched with 2 µg Se (as Na2SeO3)/L as recommended by Winner (1989), and maintained at 25 ± 1°C.- Type and amount of food: mixture of Cerophyl® (Cerophyl Laboratories, Inc. Kansas CIty, MO) and the green alga Selenastrum capricornutum, added to the daphnid culture to achieve final concentrations of 120 µg Cerophyl®/mL and Selenastrum capricornutum 6.7 x 100000 cells/mL.- Feeding frequency: up to the initiation of test
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
- Hardness:
- 164 mg/L (as CaCO3)
- Test temperature:
- 25 +/- 1°C
- pH:
- 8.5
- Dissolved oxygen:
- 8.1 mg/L
- Nominal and measured concentrations:
- Nominal concentration: 5.8, 9.7, 16, 27, 45 mg/LMeasured concentration (mean): 5.48, 9.45, 15.53, 26.98, 44.8 mg/L
- Details on test conditions:
- TEST SYSTEM- Test vessel: 0.05 L glass beaker- Fill volume: 0.03 L- Volume addition per day: 1 (mean volume addition per day for the complete exposure period)- Renewal rate of test solution (frequency/flow rate): renewed at 24 h- No. of organisms per vessel: 10- No. of vessels per concentration (replicates): 2- No. of vessels per control (replicates): 2TEST MEDIUM / WATER PARAMETERS- Source/preparation of dilution water: Non-chlorinated deep well located at The Johns Hopkins University Applied Physics Laboratory (JHU/APL) in Shady Side, MD.- Total organic carbon: 19 mg/L- Metals: Sb, As, Be, Pb, se, Tl < 0.005 mg/L, Cd < 0.001 mg/L, Cr < 0.05 mg/L, Cu < 0.02 mg/L, Hg < 0.0002 mg/L, Ni < 0.2 mg/L, Ag <0.01 mg/L, Zn < 0.04 mg/L- Alkalinity:159 mg CaCO3/L- Conductivity: 409 µmhos/cm- The water used in was analyzed for 43 Priority Pollutants, eight nonpriority, but "Hazardous" substances, 26 pesticides, and 13 metals. None of them were detected with detection limits of 2, 2, 0.1 µg/, and <0.2 - <0.0002 mg/, respectively.- Intervals of water quality measurement: A comprehensive chemical analysis of the well water was conducted two times during the study. The analyses were separated by approx. 18 months.OTHER TEST CONDITIONS- Photoperiod: 16-h light:8-h dark - Light intensity: fluorescent lights, 60-85 foot candles at the surface of the test chambersEFFECT PARAMETERS MEASURED (with observation intervals if applicable): mortality at 24 and 48 hrsTEST CONCENTRATIONS- Concentrations for the determinative evaluations were set with two objectives: 1) a geometric series of five concentrations with a dilution factor of 0.6 and 2) two of the five concentrations to produce approximately 84% survival and 84% death, respectively.
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 17.83 mg/L
- Nominal / measured:
- meas. (arithm. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Remarks on result:
- other: 16.48-19.51 mg/L
- Reported statistics and error estimates:
- The LC50 value was determined by the moving average angle method, using an EPA statistical program (Stephan, 1978).
- Conclusions:
- The 48 hr. LC50 of TNG for C. dubia was 17.83 mg/; 95% C.L. = 16.48 – 19.51 mg/L.
Reference
Description of key information
The contact of the nitroglycerine with the marine water is impossible in normal conditions of its production and using of explosives.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 17.83 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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