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Diss Factsheets
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EC number: 203-372-4 | CAS number: 106-20-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Acutely toxic to fish.
Key value for chemical safety assessment
Additional information
In a BASF study conducted in 1983 the toxicity of the test substance on the Golden orfe (Leuciscus idus) was determined. Acetone was used in the preparation of the test solutions, but was removed prior to exposure. The test concentrations were not analytically verified. Undissolved test material was observed over the whole exposure period in the test concentrations 1.47 to 3.16 mg/L.The 96 -h LC50 was >1.5 and < 2.2 mg/L (BASF AG 83/228, 1983). The pH values were in the same magnitude in all concentrations throughout the test duration.
The supporting study (BASF SE 17F0454/11E135, 2013) was a screening test conducted with Danio rerio based on OECD 203. In this limit test, all fish died at the nominal concentration of 5 mg/L after 24 h of exposure.
The screening test was performed to proof the surprisingly high toxicity to fish of this substance compared to aquatic invertebrates and algae. Other members of this chemical class (amines) have a lower toxic effect to fish compared to the other trophic levels. In the available acute toxicity study (BASF AG, 1983; report no. 83/228) undissolved test substance was present in the test medium. In order to exclude that physical effects of these particles might have caused the high mortality instead of the inherent properties of the substance, the screening test was designed to eliminate the presence of undissolved test substance.
The test was designed as limit test with a test concentration slightly above the EC50 values for Daphnia and algae (5 mg/L). The number of fish was also minimised (n = 5). To ensure that the organisms were only exposed to dissolved test substance, the exposure was carried out in stainless steel aquaria into which are placed containment chambers consisting of a glass tube with a stainless steel mesh bottom. Undissolved substance remained on the water surface inside the containment chamber but no undissolved substance was observed outside.
All fish died within 24 h, which proved the high toxic effect of the test substance.
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