Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-352-0 | CAS number: 139-08-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Study period:
- January, 2005
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Justification for type of information:
- Refer to section 13 for details on the read-across justification. The study with the read across substance is considered sufficient to fulfil the information requirements as further explained in the provided endpoint summary.
- Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Deviations:
- no
- GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- >106 CFU/mL; consisting of micro-organisms in mud collected from Station Epuration Wavre 2nd Stage, a household water treating plant
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 5 other: mgC/L
- Based on:
- test mat.
- Details on study design:
- Test conditions:
- Test temperature: 22 ± 2°C
- pH: 7.3 at start and 7.8 at the end of study
- Aeration of dilution water: Air free from carbon dioxide was passed through the solutions using a flow of 50 to 100 mL/min
- Continuous darkness: Yes
- Other: Total organic carbon content: 62.8%
Test system:
- Culturing apparatus: 3-litre flasks mounted with an aeration tube on a magnetic stirrer
- Details of trap for CO2 and volatile organics if used: the CO2 produced in each flask was precipitated with Ba(OH2). The amount of CO2 produced was determined by titration. - Reference substance:
- benzoic acid, sodium salt
- Remarks:
- 20 mgC/L
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 95.5
- Sampling time:
- 28 d
- Details on results:
- - The biodegradability in the test flask was determined to be 95.5% after 28 days (See Table 1 under 'Any other information on results inc. tables).
- The CO2 production in the blank (inoculum control) was 39.2 mg. The pH measured at the start and end of the test period was 7.3 and 7.8, respectively. The temperature throughout the test ranged from 20.8 to 21.4°C. - Results with reference substance:
- The biodegradability in the reference flask was determined to be 88.9% after 28 days (See Table 1 under 'Any other information on results inc. tables).
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- Based on the results of read across substance study, the test substance can also be considered to be readily biodegradable.
- Executive summary:
A study was conducted to determine the biodegradation of the read across substance, C12-16 ADBAC, in water according to OECD Guideline 301B (CO2 evolution test). Flasks containing inoculum from a household water-treating plant dosed with the equivalent of 5 mg C/L test or 20 mg C/L reference substances were maintained for 28 d. Biodegradability was calculated from the released CO2 over time in the test and reference flasks compared to the blank control (a flask prepared without test or reference substance). CO2 production in the blank (inoculum control) was 39.2 mg. Biodegradability in the reference flask was determined to be 88.9% after 28 d. Under the test conditions, the biodegradation of the test substance in water was determined to be 95.5% after 28 d (CO2 evolution). The test substance was considered to be readily biodegradable (van Dievoet, 2005). Based on the results of read across substance study, the test substance can also be considered to be readily biodegradable.
Reference
Table 1. Biodegradability values:
Day |
Reference substance |
Test substance |
||
% CO2Produced |
% CO2 Total |
% CO2Produced |
% CO2 Total |
|
0 |
0.00 |
0.00 |
0.0 |
0.0 |
1 |
14.16 |
14.16 |
1.2 |
1.2 |
3 |
28.54 |
42.69 |
1.0 |
2.2 |
6 |
21.20 |
63.89 |
9.5 |
11.6 |
8 |
8.77 |
72.67 |
16.0 |
27.7 |
10 |
3.72 |
76.39 |
20.2 |
47.9 |
13 |
3.26 |
79.65 |
17.4 |
65.3 |
15 |
2.53 |
82.18 |
7.5 |
72.8 |
17 |
1.47 |
83.65 |
5.1 |
77.9 |
20 |
2.31 |
85.95 |
3.9 |
81.8 |
22 |
1.15 |
87.11 |
1.6 |
83.5 |
24 |
0.25 |
87.36 |
4.4 |
87.8 |
28 |
0.16 |
87.52 |
1.8 |
89.6 |
29 |
1.35 |
88.87 |
5.8 |
95.5 |
Description of key information
Based on the results of read across substance study, the test substance, C14 ADBAC, can also be considered to be readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
A study was conducted to determine the biodegradation of the read across substance, C12-16 ADBAC, in water according to OECD Guideline 301B (CO2 evolution test). Flasks containing inoculum from a household water-treating plant dosed with the equivalent of 5 mg C/L test or 20 mg C/L reference substances were maintained for 28 d. Biodegradability was calculated from the released CO2 over time in the test and reference flasks compared to the blank control (a flask prepared without test or reference substance). CO2 production in the blank (inoculum control) was 39.2 mg. Biodegradability in the reference flask was determined to be 88.9% after 28 d. Under the test conditions, the biodegradation of the test substance in water was determined to be 95.5% after 28 d (CO2 evolution) and the test substance was considered to be readily biodegradable (van Dievoet, 2005). Based on the results of read across substance study, the test substance, C14 ADBAC, can also be considered to be readily biodegradable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.