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EC number: - | CAS number: -
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- REPORTING FORMAT FOR THE ANALOGUE APPROACH
1. HYPOTHESIS FOR THE ANALOGUE APPROACH
This read-across is based on the hypothesis that source and target substances have similar toxicological and ecotoxicological properties because they share structural similarities with common functional groups: quaternary amines, esters, and fatty acid chains varying in their length and degree of (un)saturation. Moreover, the fatty acid chains are chemically simple structures which have no structural alerts for toxicity, and which are closely related to substances of known low toxicity (i.e. stearic acid, oleic acid, linoleic acid, linolenic acid). Furthermore, the substances can be expected to have comparable breakdown products (MDEA or MDIPA and long chain fatty acids).
This read-across hypothesis corresponds to scenario 2 - different compounds have qualitatively and quantitatively the same type of effects - of the read-across assessment framework i.e. properties of the target substance MDEA-Esterquat C18 unsatd. are predicted to be similar to those of the source substances MDIPA Esterquat C18 unsatd., MDEA-Esterquat C16-18 and C18 unsatd. and MDIPA-Esterquat C16-18 and C18 unsatd.
Therefore, read-across from the available physicochemistry, toxicity and ecotoxicity studies with the source substances MDIPA Esterquat C18 unsatd., MDEA-Esterquat C16-18 and C18 unsatd. and MDIPA-Esterquat C16-18 and C18 unsatd. are considered as an appropriate adaptation to the standard information requirements of the REACH Regulation for the target substance MDEA-Esterquat C18 unsatd., in accordance with the provisions of Annex XI, 1.5 of the REACH Regulation.
2. SOURCE AND TARGET CHEMICAL(S) (INCLUDING INFORMATION ON PURITY AND IMPURITIES)
please refer to read-across justification attached to Iuclid section 13
3. ANALOGUE APPROACH JUSTIFICATION
please refer to read-across justification attached to Iuclid section 13
4. DATA MATRIX
please refer to read-across justification attached to Iuclid section 13 - Reason / purpose for cross-reference:
- read-across: supporting information
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Temp.:
- 20 °C
- Vapour pressure:
- < 0 Pa
- Conclusions:
- Based on read-across, the vapour pressure of MDEA-Esterquat C18 unsatd is <8.4E-07 Pa at 20°C.
Reference
Description of key information
<8.4E-07 Pa at 20°C (read across from substances MDEA-Esterquat C16-18 and C18 unsatd., MDIPA Esterquat C18 unsatd., and MDIPA-Esterquat C16-18 and C18 unsatd.)
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 20 °C
Additional information
No experimental data on vapour pressure are available for the target substance MDEA-Esterquat C18 unsatd. However, based on structural similarities, a similarly low vapour pressure can be expected as for the source substances MDEA-Esterquat C16-18 and C18 unsatd., MDIPA Esterquat C18 unsatd., and MDIPA-Esterquat C16-18 and C18 unsatd. A justification for read-across is attached to Iuclid section 13.
The vapour pressure of the main constituent of MDEA-Esterquat C16-18 and C18 unsatd. was calculated to be 7.33E-18 Pa at 25°C (EpiSuite V4.11, MPBPVP v1.43, Modified Grain method).
The vapour pressure of MDIPA Esterquat C18 unsatd. was determined according to OECD Guideline 104 (23 March 2006) and EU Method A.4 (30 May 2008) using the vapour pressure balance method. Based on the experimental results, the vapour pressure of the test item at 20°C was calculated to be 5E-06 hPa using the Antoine equation.
The vapour pressure of MDIPA-Esterquat C16-18 and C18 unsatd. was determined according to OECD Guideline 104. The isothermal TGA effusion method was applied.
The vapour pressure of MDIPA-Esterquat C16-18 and C18 unsatd. at 20 °C (293K) and at 25 °C (298K) was below 8.4E-7 Pa and below 2.2E-6 Pa.
The weight losses of the test substance were obtained with a temperature program of above the melting temperature of the test substance.
Based on read-across, the vapour pressure of MDEA-Esterquat C18 unsatd is <8.4E-07 Pa at 20°C.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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