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EC number: 619-057-3 | CAS number: 94667-33-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2001-05-02 to 2001-06-15
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.7 (Degradation: Abiotic Degradation: Hydrolysis as a Function of pH)
- Deviations:
- no
- Principles of method if other than guideline:
- Not relevant.
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
No information provided. - Radiolabelling:
- not specified
- Analytical monitoring:
- yes
- Details on sampling:
- Sample solutions were prepared in stoppered glass flasks at a nominal concentration of 4 g/L in the three buffer solutions at pH 4, pH 7 and pH 9, using a 1% methanol co-solvent.
The solutions were shielded from light whilst maintained at the test temperature. - Buffers:
- pH4, pH7 and pH9
The buffer solutions were filtered through a 0.2 µm membrane filter to ensure they were sterile before commencement of the test. Also these solutions were subjected to ultrasonication and degassing with nitrogen to minimise dissolved oxygen content. - Estimation method (if used):
- not applicable.
- Details on test conditions:
- TEST SYSTEM
- Type, material and volume of test flasks, other equipment used: Stoppered glass flasks.
- Measures taken to avoid photolytic effects: Solutions were shielded from light.
Preliminary test/test 1
The sample solutions at pH 4, 7 and 9 were shielded from light and maintained at 50.0 +/- 0.5°C for a period of 5 days. - Duration:
- 5 d
- pH:
- 4
- Temp.:
- 50 °C
- Initial conc. measured:
- 2.56 g/L
- Duration:
- 5 d
- pH:
- 7
- Temp.:
- 50 °C
- Initial conc. measured:
- 4.28 g/L
- Duration:
- 5 d
- pH:
- 9
- Temp.:
- 50 °C
- Initial conc. measured:
- 4.18 g/L
- Number of replicates:
- Duplicate aliquots (A and B).
- Positive controls:
- no
- Negative controls:
- no
- Statistical methods:
- The mean peak area of each standard was corrected to a nominal concentration of 80 mg/L and the mean value taken. The concentration of the sample solutions (g/L) was calculated using Equation 4.1.
- Preliminary study:
- Preliminary test and test 1 were performed in the same time and buffer conditions.
- Test performance:
- No degradation occurred during the incubation period.
- Transformation products:
- not measured
- Details on hydrolysis and appearance of transformation product(s):
- At all three pH's tested, less than 10% hydrolysis after 5 days at 50degC, equivalent to a half-life greater than 1 year at 25degC.No degradation occurred during the incubation period.
- % Recovery:
- ca. 100
- pH:
- 4
- Temp.:
- 50 °C
- Duration:
- 120 h
- % Recovery:
- ca. 100
- pH:
- 7
- Temp.:
- 50 °C
- Duration:
- 120 h
- % Recovery:
- ca. 100
- pH:
- 9
- Temp.:
- 50 °C
- Duration:
- 120 h
- Key result
- pH:
- 4
- Temp.:
- 25 °C
- DT50:
- > 1 yr
- Type:
- (pseudo-)first order (= half-life)
- Key result
- pH:
- 7
- Temp.:
- 25 °C
- DT50:
- > 1 yr
- Type:
- (pseudo-)first order (= half-life)
- Key result
- pH:
- 9
- Temp.:
- 25 °C
- DT50:
- > 1 yr
- Type:
- (pseudo-)first order (= half-life)
- Other kinetic parameters:
- No information provided.
- Details on results:
- N,N-Didecyl-N-methylpoly(oxyethly)ammonium Propionate is hydrolytically stable at 25°C at pH 4, 7 and 9 for over 1 year.
Less than 10% hydrolysis after 5 days at 50°C, equivalent to a half-life greater than 1 year at 25°C. - Validity criteria fulfilled:
- yes
- Conclusions:
- N,N-Didecyl-N-methylpoly(oxyethly)ammonium Propionate is hydrolytically stable at 25°C at pH 4, 7 and 9 for over 1 year, under the conditions of this study.
- Executive summary:
In a study conducted in accordance with Directive 92/69/EEC, C.7, the hydrolysis of N,N-Didecyl-N-methylpoly(oxyethly)ammonium Propionate was assessed at a concentration of 4g/L in buffer solutions at pH 4, pH 7 and pH 9. Samples were incubated at 50°C for 5 days and shielded from light. No degradation occurred during the incubation period. N,N-Didecyl-N-methylpoly(oxyethly)ammonium Propionate is hydrolytically stable at 25°C at pH 4, 7 and 9 for over 1 year.
Reference
It was noted that the initial concentration analysed at pH 4 was somewhat lower that the stock fortification concentration. This is possibly due to the solubility of the test material at this pH, as during method development it proved difficult to prepare stock solutions at sufficient concentration for testing at this pH. This was considered not to have affected the result of the test, which was an investigation into rate of hydrolysis, as the test material was seen to be stable at the analysed concentration over the duration of the test.
Description of key information
No degradation occurred during the incubation period. N,N-Didecyl-N-methylpoly(oxyethly)ammonium Propionate is hydrolytically stable at 25°C at pH 4, 7 and 9 for over 1 year.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 1 yr
- at the temperature of:
- 25 °C
Additional information
In a study conducted in accordance with Directive 92/69/EEC, C.7, the hydrolysis of N,N-Didecyl-N-methylpoly(oxyethly)ammonium Propionate was assessed at a concentration of 4g/L in buffer solutions at pH 4, pH 7 and pH 9. Samples were incubated at 50°C for 5 days and shielded from light. No degradation occurred during the incubation period. N,N-Didecyl-N-methylpoly(oxyethly)ammonium Propionate is hydrolytically stable at 25°C at pH 4, 7 and 9 for over 1 year.
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