Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
200-659-6
CAS no.:
67-56-1
Index number:
Molecular formula:
CH4O
SMILES:
CO
InChI:
InChI=1S/CH4O/c1-2/h2H,1H3
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
46
Of which contain:
11 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance is toxic if swallowed, is toxic in contact with skin, is toxic if inhaled, causes damage to organs and is a highly flammable liquid and vapour.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is suspected of causing cancer.

Breakdown of all 7287 C&L notifications submitted to ECHA

Flam. Liq. 2 H225 Harmonised Classification
Acute Tox. 3 H331 Harmonised Classification
STOT SE 1 H370 Harmonised Classification
Acute Tox. 3 H301 Harmonised Classification
Acute Tox. 3 H311 Harmonised Classification
Eye Irrit. 2 H319
Repr. 1B H360
STOT RE 1 H372
Skin Irrit. 2 H315
Not Classified
Carc. 2 H351
STOT SE 3 H336
Acute Tox. 2 H300
Acute Tox. 1 H310
Skin Corr. 1A H314
https://chesar.echa.europa.eu/diss-blank-theme/images/cnl/graph/more.png 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://chesar.echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://chesar.echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://chesar.echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

  • PBT
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Persistent, Bioaccumulative and Toxic (0.38% of REACH registrations).

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 248 active registrations under REACH, 2 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Substance included in the Community Rolling Action Plan (CoRAP).
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):
Some uses of this substance are restricted under Annex XVII of REACH.

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 1 000 000 - 10 000 000 tonnes per year.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: washing & cleaning products, anti-freeze products and fuels.

Other release to the environment of this substance is likely to occur from: outdoor use and indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

This substance is used in the following activities or processes at workplace: batch processing in synthesis or formulation with opportunity for exposure and production of mixtures or articles by tabletting, compression, extrusion or pelletisation.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal) and of articles where the substances are not intended to be released and where the conditions of use do not promote release. Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance can be found in products with material based on: plastic.

This substance is used in the following products: laboratory chemicals, fuels, pH regulators and water treatment products and washing & cleaning products.

This substance is used in the following areas: health services, scientific research and development and formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, roller or brushing applications, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, treatment of articles by dipping and pouring, laboratory work and non-industrial spraying.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

This substance is used in the following products: laboratory chemicals, pH regulators and water treatment products, polymers, coating products, inks and toners and textile treatment products and dyes.

This substance is used in the following activities or processes at workplace: transfer of chemicals, transfer of substance into small containers, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure, closed batch processing in synthesis or formulation and laboratory work.

Release to the environment of this substance can occur from industrial use: formulation of mixtures and manufacturing of the substance.

This substance is used in the following products: laboratory chemicals, water treatment chemicals, fuels, washing & cleaning products, polymers and pH regulators and water treatment products. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, closed processes with no likelihood of exposure, batch processing in synthesis or formulation with opportunity for exposure, laboratory work and roller or brushing applications.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, of substances in closed systems with minimal release, as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, laboratory work and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, as an intermediate step in further manufacturing of another substance (use of intermediates), in processing aids at industrial sites, as processing aid and formulation of mixtures.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

General statements

If medical advice is needed, have product container or label at hand.

Prevention statements

When handling this substance: do not breathe the dust, fume, gas, mist, vapours or spray; keep away from heat, sparks, open flames and/or hot surfaces – No smoking; use only outdoors or in a well-ventilated area; keep container tightly closed; use personal protective equipment as required.; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If exposed or you feel unwell: call a poison center or doctor/physician. If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower.

Storage statements

Store this substance locked up.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • 3M Belgium BVBA/SPRL, Hermeslaan 7 1831 Diegem Belgium
  • AB Achema, Jonalaukio km. Ruklos sen. LT55550 Jonavos r. Lithuania
  • Abbott Diagnostics GmbH, Max Planck Ring 2 D-65205 Delkenheim Germany
  • ACOMON S.R.L., VIA BAIONA, 107 48100 RAVENNA ITALY Italy
  • Acros Organics bvba, Janssen Pharmaceuticalaan 3a B-2440 Geel Belgium
  • Actu-All Chemicals B.V., Randmeer 36 5347 JW OSS Netherlands
  • ADEKA Europe GmbH, Berliner Allee 22 40212 Düsseldorf Germany
  • Afton Chemical S.P.R.L. (Woluwe), Alma Court Lenneke Marelaan, 8 B-1932 St-Stevens-Woluwe Belgium
  • AGC Chemicals Europe, Ltd., York House Hillhouse FY5 4QD Thornton Cleveleys Lancashire United Kingdom
  • Allnex Belgium NV/SA OR1, Anderlechtstraat 33 1620 Drogenbos Belgium
  • Allnex Belgium NV/SA OR5, Anderlechtstraat 33 1620 Drogenbos Belgium
  • ALSG (Air Liquide Spatial Guyane), Route de l'Espace, RN 1 Bâtiment Lavoisier - BP 826 F 97388 KOUROU France
  • ANDREAS GALAXIS CO Ltd, 9, Kallistratous Street, Engomi Industrial Area 2409 Nicosia Cyprus
  • ANNO chemicals N.V., Berkenlaan 21 2980 Halle (Zoersel) (Antwerp) Belgium
  • ARKEMA FRANCE, 420 rue d'Estienne d'Orves 92700 COLOMBES France
  • AS DBT, Narva mnt 7D 10117 Tallinn Estonia
  • Ascensus Specialties BVBA, Koningsstraat 97 B-1000 Brussel Brussels Belgium
  • Atlantic Methanol Services B.V., Zuidplein 126 WTC Tower H, 15th Floor 1077XV Amsterdam Netherlands
  • Avantor Performance Materials Poland S.A., Sowińskiego 11 44-100 Gliwice Poland
  • B-Lands Consulting (81111100-4), World Trade Center, 5 Place Robert Schuman - BP 1510 38025 Grenoble France France
  • B-Lands Consulting (811222-8), World Trade Center, 5 Place Robert Schuman - BP 1510 38025 Grenoble France France
  • B-Lands Consulting (811280-8), World Trade Center, 5 Place Robert Schuman - BP 1510 38025 Grenoble France France
  • B-Lands Consulting (811322-5), World Trade Center, 5 Place Robert Schuman - BP 1510 38025 Grenoble France France
  • B-Lands Consulting (811698-1), OR of Jingzhou Jianghan Fine Chemical Co., Ltd 5 Place Robert Schuman - BP 1516 38025 Grenoble France France
  • Baker Hughes Ltd, The Ark, 201 Talgarth Road Hammersmith W6 8BJ London United Kingdom
  • BASF Construction Additives GmbH , Dr.Albert Frank Strasse 32 83308 Trostberg Germany
  • BASF Construction Solutions GmbH, Dr.-Albert-Frank-Strasse 32 83308 Trostberg Germany
  • BASF Espanola S.L., Calle Can Ràbia, n. 3-5 8017 Barcelona Spain
  • BASF Health and Care Products France S.A.S., 49, Avenue Georges Pompidou 92593 Levallois-Perret Cedex France
  • BASF Personal Care and Nutrition GmbH, Henkelstr. 67 40589 Düsseldorf Germany
  • BASF Schwarzheide GmbH, Schipkauer Str. 1 01987 Schwarzheide Brandenburg Germany
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • BBI Technologies Europe Limited, 2nd Floor 1-2 Victoria Buildings Haddington Road Dublin 4 Dublin Ireland
  • Beckman Coulter France SAS, Paris Nord 2 33 Rue des Vanesses 95942 Roissy CDG CEDE France
  • Beckman Coulter GmbH, Europark Fichtenhain B13 47807 Krefeld Germany
  • Beckman Coulter Ireland Inc, Lismeehan none O'Callaghan's Mills Clare Ireland
  • Beckman Coulter, S.L.U., Plaza Europa 41-43 L'Hospitalet de Llobregat 08902 Barcelona Spain
  • Becton Dickinson Distribution Center NV, Laagstraat 57 9140 Temse Belgium
  • Bio Methanol Chemie Nederland BV, Oosterhorn 10 9936HD Farsum Netherlands
  • Blue Cube Germany Assets GmbH & Co. KG, Buetzflether Sand 2 21683 Stade Germany
  • BNH-OIL Polska Sp. z o.o., ul.Tadeusza Rejtana 17, lok 14 02-516 Warszawa Poland
  • BP Chemicals Ltd, Chertsey Rd TW16 7BP Sunbury on Thames Middlesex United Kingdom
  • BP Europa SE, Überseeallee 1 20457 Hamburg Germany
  • BP Oil International, Chertsey Road TW16 7BP Sunbury on Thames Middlesex United Kingdom
  • BP Raffinaderij Rotterdam B.V., d'Arcyweg 76 3198 NA Europoort Rotterdam Netherlands
  • Brenntag Holding GmbH , Messeallee 11 45131 Essen Germany
  • BYK-Chemie GmbH, Abelstr. 45 DE-46483 Wesel Germany
  • C.S.B. GmbH, Düsseldorfer Str. 113 47809 Krefeld Germany
  • CAFFARO INDUSTRIE S.P.A, piazzale Marinotti 1 33050 Torviscosa (UDINE) Italy
  • Carbon Recycling International, Holtasmari 1 IS-201 Kopavogur Iceland
  • CATERWAYS COMPANY LTD, TRIPOLEOS 68 2235 Nicosia Cyprus
  • CBC (Europe) GmbH, Hansaallee 191 40549 Duesseldorf Germany
  • CCD (Germany) GmbH, Graf-Adolf-Strasse 68 40210 Düsseldorf Germany
  • CCI Manufacturing Germany GmbH, Borsigstr. 12 41541 Dormagen Germany
  • Celanese Production Germany GmbH & Co. KG, Am Unisys-Park 1 65843 Sulzbach Germany
  • CEPSA Química, S.A., Torre CEPSA Paseo de Castellana 259A 28046 Madrid Spain
  • CH.THEOTOKIS LTD, ZANETTOU 26 1100 Nicosia AYIOS ANDREAS Cyprus
  • Charles River Laboratories Den Bosch B.V. OR18, Hambakenwetering 7 5231 DD 's-Hertogenbosch Netherlands
  • Chemetall GmbH, Trakehner Str. 3 60487 Frankfurt Germany
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Chemours Netherlands B.V., Baanhoekweg 22 3313 LA Dordrecht Netherlands
  • Chemsafe srl, Via Ribes 5 10010 Colleretto Giacosa (TO) Italy
  • Chimica Pomponesco Spa, Via delle Industrie, 1 46030 Pomponesco Lombardia Italy
  • Chimitrade Spa, Piazza Duca D'Aosta 12 20124 Milano Italy
  • CHT Germany GmbH, Bismarckstr. 102 72072 Tuebingen Germany
  • Clariant Ibérica Producción S.A., Avda. Baix Llobregat, 3-5 08970 Sant Joan Despí Barcelona Spain
  • Clariant Produkte (Deutschland) GmbH, Am Unisys-Park 1 65843 Sulzbach am Taunus Germany
  • COVANCE CRS SA 148, Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 - 5 Planta 28050 Madrid Spain
  • Covestro Deutschland AG, Kaiser-Wilhelm-Allee 60 51373 Leverkusen Germany
  • Cytec Industries B.V. OR, Burgemeester van Lierplein 75 3134 ZB Vlaardingen Netherlands
  • Cytec Industries BV, Burgemeester van Lierplein 75 3134 ZB Vlaardingen Netherlands
  • Desatec GmbH, Raboisen 32 20095 Hamburg Germany
  • DHW Deutsche Hydrierwerke GmbH Rodleben, Brambacher Weg 1 06861 Dessau - Rosslau Saxony - Anhalt Germany
  • DOW BENELUX B.V. OR-10, Postbus 48 4530 AA Terneuzen Netherlands
  • Dow Silicones Belgium SPRL OR-1, PSRC - rue Jules Bordet Parc industriel C 7180 Seneffe Belgium
  • Dow Silicones UK Limited, PSRC - Cardiff Road CF632YL Barry, South Glamorgan Wales United Kingdom
  • DSM Advanced Solar BV, Urmonderbaan 22 6167 RD Geleen Netherlands
  • DSM Engineering Plastics (Emmen) B.V., Urmonderbaan 22 6167RD Geleen The Netherlands Netherlands
  • DSM Nutritional Products (UK) Ltd, Delves Road Heanor Gate DE75 7SG Heanor Derbyshire United Kingdom
  • DSM Nutritional Products GmbH, Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany
  • DUBAY Polymer GmbH, Frielinghauser Strasse 5 D-59071 Hamm Germany
  • DuPont de Nemours (Luxembourg) S.a.r.l., Rue General Patton 2984 Contern Luxembourg
  • DuPont Solutions (France) SAS, Saint Quentin en Yvelines 78180 Paris France
  • DuPont Teijin Films Luxembourg SA, Rue Général Patton, Contern LU-1016 Luxembourg Luxembourg
  • DyStar Colours Distribution GmbH, Am Prime-Parc 12 65479 Raunheim Germany
  • Ecofuel SpA, Via Felice Maritano 26 20097 SAN DONATO MILANESE Italy
  • EGIS Pharmaceuticals PLC, Keresztúri út 30-38 H-1106 Budapest Hungary
  • ELC GROUP s.r.o, Karolinská 650/1 18600 Prague 8 Czech Republic
  • Envigo Research Limited, Shardlow Business Park London Road DE72 2GD Shardlow Derbyshire United Kingdom
  • Equinor ASA, Forusbeen 50 N-4035 Stavanger Norway
  • Ercros SA, Avenida Diagonal 593-595 08014 Barcelona Spain
  • EVAL Europe, Haven 1053 Nieuwe Weg 1 B2070 Zwijndrecht Antwerp Belgium
  • Evonik Italia S.r.l., Via Falconera, 7 26025 Pandino (CR) Italy
  • Evonik Nutrition & Care GmbH, Rellinghauser Straße 1-11 45128 Essen North Rhine-Westfalia Germany
  • Evonik Operations GmbH, Rellinghauser Straße 1 - 11 C-ES 45128 Essen North Rhine-Westfalia Germany
  • Evonik Oxeno Antwerpen N.V., Tijsmanstunnel West 2040 Antwerpen Belgium
  • Evonik Performance Materials GmbH, Rellinghauser Strasse 1-11 45128 Essen Germany
  • Evonik Resource Efficiency GmbH, Rellinghauser Strasse 1-11 45128 Essen Germany
  • Evonik Röhm GmbH, Kirschenallee 64293 Darmstadt Germany
  • ExponentOR11G, Kanzlerstraße 4 D-40472 Düsseldorf Germany
  • FujiFilm Manufacturing Europe BV, Oudenstaart 1 5047 TK Tilburg Netherlands
  • Gelsenchem Chemical Products GmbH, Bebelallee 1 22299 Hamburg Germany
  • GEO SPECIALTY CHEMICALS UK LIMITED, Charleston Road Hardley, Hythe, SO45 3ZG Southampton Hampshire United Kingdom
  • Glencore Energy UK Ltd, 50 Berkeley Street W1J 8HD London United Kingdom
  • Hellenic Petroleum S.A., 8Α Chimarras st. GR 15125 Maroussi Attica Greece
  • Helm AG, Nordkanalstraße 28 20097 Hamburg Germany
  • HELM AG, Nordkanalstraße 28 20097 Hamburg Germany
  • HELM AG, Nordkanalstr. 28 20097 Hamburg Germany
  • Henkel Global Supply Chain B.V., Gustav Mahlerlaan 2970 1081 LA Amsterdam Netherlands
  • Hexion B.V., Seattleweg 17, building 4 3195 ND Pernis-Rotterdam Netherlands
  • HH Compliance Ltd., Rubicon Building, CIT-Campus Bishopstown none Cork Ireland
  • HH Compliance Ltd., The Rubicon Centre, CIT Campus, 0000 Bishopstown, Cork Ireland
  • Hitachi Europe GmbH, Niederkasseler Lohweg 191 40547 Düsseldorf Germany
  • Honeywell Specialty Chemicals Seelze GmbH, Wunstorfer Strasse 40 D-30926 Seelze Lower Saxony Germany
  • HUNTSMAN HOLLAND BV, Merseyweg 10 3197 KG Botlek-Rotterdam Netherlands
  • Huntsman Textile Effects (Germany) GmbH, Rehlinger Str. 1 D-86462 Langweid a.Lech Germany
  • Indorama Ventures Polymers Germany GmbH, Philipp Reis Strasse 2 65795 Hattersheim Germany
  • INEOS nv, Haven 1053 -- Nieuwe Weg 1 2070 Zwijndrecht Belgium
  • Innospec Limited, Innospec Manufacturing Park Oil Sites Road CH65 4EY Ellesmere Port Cheshire United Kingdom
  • Innospec Limited (OR1), Innospec Manufacturing Park Oil Sites Road CH65 4EY Ellesmere Port Cheshire United Kingdom
  • INNOSPEC PERFORMANCE CHEMICALS SPAIN S.L., Polígono Zona Franca Sector F, Calle 43 Nº 10 8040 Barcelona Spain
  • Intertek Deutschland GmbH, Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany
  • Intertek Deutschland GmbH 09, Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany
  • ITW Performance Polymers, A Division of ITW Ireland, Bay 150 Shannon Industrial Estate V14 DF82 Shannon Co. Clare Ireland
  • IVICT Europe GmbH, Kennedydamm 19 40476 Düsseldorf Germany
  • Jobachem GmbH, Am Burgberg 13 37586 Dassel Lower Saxony Germany
  • Kaneka Belgium N.V., Nijverheidsstraat 16 B-2260 Westerlo Antwerp Belgium
  • Kem One, IMMEUBLE LE QUADRILLE 19 RUE JACQUELINE AURIOL 69008 LYON France
  • KEMIRA ITALY S.P.A, Via E. Majorana 8 33058 San Giorgio di Nogaro (UD) Italy
  • Kemira Oyj, Energiakatu 4 P.O.Box 330 FI-00101 HELSINKI Finland
  • Knoell NL-OR-047, Agro Business Park 75 6708PV Wageningen Netherlands
  • Knoell NL_OR_058, Agro Business Park 75 6708 PV Wageningen Netherlands
  • Knoell NL_OR_059, Agro Business Park 75 6708 PV Wageningen Netherlands
  • Kolmar NL BV, Claude Debussylaan 10 1082MD Amsterdam Netherlands
  • Kronospan Sebes SA, Mihail Kogalniceanu Nr 59 515800 Sebes jud.Alba Romania Romania
  • Kuraray Europe GmbH, Philipp-Reis-Str. 4 65795 Hattersheim Germany
  • Kuraray Europe GmbH (OR1), Philipp-Reis-Str. 4 65795 Hattersheim Germany
  • labbox labware s.l., Joan Peiró i Belis, 2 08339 Vilassar de Dalt BARCELONA Spain
  • Leica Biosystems Nussloch GmbH, Heidelberger Straße 17-19 69226 Nussloch Germany
  • Leuna-Tenside GmbH, Am Haupttor Gebäude 7302 06237 Leuna Germany
  • Lifosa-2, Juodkiskio 50 LT-57502 Kedainiai Lithuania
  • Lifosa-4, Juodkiskio 50 LT-57502 Kedainiai Lithuania
  • Livchem Logistics GmbH, Fritz-Klatte-Strasse 8 D-65933 Frankfurt Germany
  • Lonza Cologne GmbH, Nattermannallee 1 50829 Cologne Germany
  • LORD Germany GMBH, Ottostrasse 28 41836 Hueckelhoven North Rhine - Westphalia Germany
  • Lubrizol Advanced Materials Europe B.V.B.A, Nijverheidsstraat 30 2260 Westerlo-Oevel Belgium
  • Lubrizol Europe Coordination Center BVBA 01, Chaussee De Wavre, 1945 1945 Brussels Belgium
  • Lubrizol Limited, The Knowle, Nether Lane Hazelwwod DE56 4AN Derby Derbyshire United Kingdom
  • Lyondell Chemie France S.A.S., Zone Industrielle Portuaire 13270 Fos sur Mer France
  • Merck KGaA, Frankfurter Strasse 64293 Darmstadt Germany
  • METACHEM S.p.A., Via Triboldi Pietro, 4 26015 SORESINA (CR) Italy
  • Metadynea Austria GmbH, Hafenstrasse 77 A-3500 Krems Austria
  • Methanex Europe SA/NV, Waterloo Office Park Building P Dreve Richelle 161 - Box 31 B-1410 Waterloo Belgium
  • Methanex UK Ltd, Eversheds House 70 Great Bridgewater Street M1 5ES Manchester Manchester United Kingdom
  • MIDER-HELM Methanol Vertriebs GmbH, Nordkanalstrasse 28 20097 Hamburg Germany
  • Milliken Europe B.V.B.A., Ham 18-24 9000 Gent Belgium
  • MITSUBISHI GAS CHEMICAL EUROPE GMBH, Immermannstr.13 40210 Duesseldorf Germany
  • MITSUBISHI GAS CHEMICAL EUROPE GMBH, Immermannstr.13 40210 Duesseldorf Germany
  • Mitsui and Co. Deutschland G.M.B.H. Head Office (Düsseldorf), Herzogstrasse 15 D-40217 Düsseldorf Germany
  • Momaja s.r.o, Karolinská 650/1 186-00 Prague 8 Czech Republic
  • Momentive Performance Materials (Benelux )BVBA, Haven 1053, Nieuwe Weg 1 B-2070 Zwijndrecht Belgium
  • Momentive Performance Materials GmbH, Chempark Building V7 51368 Leverkusen NRW Germany
  • Momentive Performance Materials Specialties Srl, Zona Industriale- Località Rivolta Del Re Termoli 86039 Termoli CB Italy
  • Monument Chemical, Haven 1972 Ketenislaan 3 9130 Kallo Belgium
  • MOTOR OIL (HELLAS) CORINTH REFINERIES S.A., Irodou Attikou 12a 15124 Marousi Athens Greece
  • Muntajat B.V., Prinses Margrietplantsoen 78-A 19th floor, Tower E, WTC The Hague 2595 BR The Hague Netherlands
  • Nafta-Petrochem d.o.o., Mlinska ulica 5 9220 Lendava Slovenia
  • Nalco Limited, P.O. Box 11, Winnington Avenue, CW8 4DX Northwich, Cheshire United Kingdom
  • Neste Oyj, Keilaranta 21 FI-02150 Espoo Finland
  • Nona Trade Corporation GmbH, Schippelsweg 53 22455 Hamburg Germany
  • Nouryon Chemicals NV/SA, Parc Industriel de Ghlin Zone A 7011 Ghlin Mons Belgium
  • NV DEVAN CHEMICALS, KLEIN FRANKRIJKSTRAAT 8 9600 RONSE BELGIE Belgium
  • Oman Trading International Limited, Javastraat 6 3016 CE Rotterdam Netherlands
  • Perstorp Specialty Chemicals AB, Perstorp Industripark SE-28480 Perstorp Sweden
  • Petrochemical Commercial Company (UK) Ltd, 24, GROSVENOR GARDENS SW1W 0DH LONDON EUROPE United Kingdom
  • Pieris Hadjiloucas Trading Co. Ltd., 19 Smyrnis street 2540 Nicosia, Dali Cyprus
  • PPG Europe B.V. - OR1, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • PPG Europe B.V. - OR3, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • PPG Europe B.V. - OR7, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • PPG Industries Italia Srl Società soggetta a direzione e coordinamento da parte di PPG Industries Inc., Via Serra, 1 15028 Quattordio Italy
  • Prefere Melamines GmbH, Alt Fechenheim 34 60386 Frankfurt am Main Germany Germany
  • Prefere Melamines GmbH - OR Indian Orchard, Alt Fechenheim 34 60386 Frankfurt am Main Germany
  • Prefere Resins Finland Oy, Öljysatamantie 16 49401 Hamina Finland
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
  • REACHLaw ltd, Vänrikinkuja 3 JK 21 02600 Espoo Finland
  • REACHLaw Ltd., Vänrikinkuja 3 JK 21 02600 Espoo Finland
  • Red Orchid Consulting Oy Ltd, Viherkallionkuja 3 I 59 02710 Espoo Finland
  • REPSOL TRADING SA, Calle Méndez Álvaro, 44 28045 Madrid Spain
  • RHODIA OPERATIONS, 40 rue de la Haie Coq 93306 AUBERVILLIERS France
  • Ricoh Industrie France SAS, 144 route de Rouffach F-68920 F-68920 Wettolsheim France
  • Roche Ireland Limited, Clarehill . Clarecastle Ireland
  • Ruhr Oel GmbH, Pawiker Strasse 30 45896 Gelsenkirchen Germany
  • S.C. VIROMET S.A., ALEEA UZINEI 505700 VICTORIA BRASOV Romania
  • SABIC Innovative Plastics BV, Plasticslaan 1 4612 PX Bergen op Zoom Netherlands Netherlands
  • SABIC Innovative Plastics Espana ScpA, Ctra. Cartagena-Alhama de Murcia km. 13. La Aljorra 30390 Cartagena Spain Spain
  • SABIC Petrochemicals B.V., Europaboulevard 1 6135 LD Sittard Netherlands
  • Sadepan Chimica S.r.l., Viale Lombardia, 29 46019 Viadana Italy
  • Sakura Finetek Europe B.V., Flemingweg 10A 2408AV Alphen aan den Rijn Netherlands
  • SARAS SpA, ss 195 km 19.2 09018 SARROCH (CA) SARDINIA Italy
  • SARLUX srl, S.S. Sulcitana 195 km. 19 09018 Sarroch (CA) Sardinia Italy
  • Sasol Chemie GmbH & Co. KG, Anckelmannsplatz 1 20537 Hamburg Germany
  • Sasol Germany GmbH, Anckelmannsplatz 1 D-20537 Hamburg Germany
  • SCAS Europe S.A./N.V., Leonardo Da Vincilaan 19 B-1831 Diegem Belgium
  • SGS EWACS NV 24, Haven 1091 Keetberglaan 4 9120 Melsele Belgium
  • Shell Chemicals Europe B.V., Weena 70 3012 CM Rotterdam Netherlands
  • Shell Deutschland Oil GmbH, Suhrenkamp 71-77, 22335 Hamburg Germany
  • Shell Nederland Raffinaderij B.V., Vondelingenweg 601 Postbus 3000 3196 KK Rotterdam Netherlands
  • Shell Trading International Ltd, Shell Centre SE1 7NA London United Kingdom
  • Shell Trading Rotterdam B. V., Weena 70 3012 CM Rotterdam Netherlands
  • Siemens Healthcare Diagnostics Products GmbH, Emil-von-Behring-Str. 76 35041 Marburg Germany
  • Sigma-Aldrich Biochemie GmbH, Georg-Heyken-Str. 14 21147 Hamburg Germany
  • SIGMA-ALDRICH CHEMIE GMBH, Riedstrasse 2 89555 Steinheim Germany
  • SIGMA-ALDRICH CHIMIE SARL, 80 Rue de Luzais BP 701 38297 Saint Quentin Fallavier France
  • Sigma-Aldrich Company Limited, The Old Brickyard, New Road SP8 4XT Gillingham United Kingdom
  • Sigma-Aldrich Ireland Ltd, Vale Road . Arklow Co. Wicklow Ireland
  • Sigma-Aldrich Sweden AB, Solkraftsvägen 14C S-135 70 Stockholm Sweden
  • Sinopec Europa GmbH, Messe Turm, Friedrich-Ebert-Anlage 49 60308 Frankfurt am Main Germany
  • SIPOL S.P.A, Leonardo da Vinci 5 27036 Mortara (Pavia) Italy
  • Solenis Netherlands B.V., Fascinatio Boulevard 522 2909 VA CAPELLE A/D IJSSEL Netherlands
  • solvadis commodity chemicals gmbh, Koenigsberger Strasse 1 60487 Frankfurt / M. Germany
  • SpetsInterProject Oy Ammoniy, Näkinkaari 1 M 02320 Espoo Finland
  • SPG Polymers GmbH, Herrmanstr. 10 20095 Hamburg Germany
  • Sustainability Support Services (Europe) AB, Markaskälsvägen 6 22647 Lund Sweden
  • Södra Skogsägarna ekonomisk förening, Skogsudden SE-35189 Växjö Sweden
  • TG Biochemicals Limited, 13 Konstantinou Paparigopoulu Street, Heathrow tower 3106 Limassol Cyprus
  • TOKUYAMA EUROPE GMBH, Am Gierath 20A 40885 Ratingen Germany
  • TORAY Films Europe, Place d'Arménie 01700 Saint Maurice de Beynost France
  • Total Lindsey Oil Refinery ltd, Eastfield Road DN40 3LW North Lincolnshire United Kingdom
  • Total Petrochemicals & Refining SA, Rue de l'Industrie,52 1040 Bruxelles Belgium
  • TOTAL RAFFINERIE MITTELDEUTSCHLAND GMBH, MAIENWEG, 1 D06237 LEUNA Germany
  • TRECO SRL, Via Romagna 8 20098 SAN GIULIANO MILANESE MILANO Italy
  • Tricon Energy Ireland Limited, One Earlsfort Centre, Lower Hatch Street Suite 3, D02 VY74 Dublin Ireland 2 Ireland
  • TÜV SÜD Industrie Service GmbH, Westendstraße 199 80686 München Germany
  • UAB “APLINKOS VADYBA”, Vilkpėdės g. 22 03151 Vilnius Lithuania
  • UMCO GmbH, Georg-Wilhelm-Straße 187 21107 Hamburg Germany
  • V. MANE FILS S.A., 620 route de Grasse 06620 Le Bar sur Loup France
  • V.V. ELECTRIC WORLD LTD, VASILEOS KONSTANTINOY 8021 PAFOS Cyprus
  • VALTRIS ENTERPRISES FRANCE, ZI Baleycourt 55103 VERDUN FRANCE France
  • Videojet Technologies Europe B.V., Strijkviertel 39 3454 PJ De Meern Utrecht Netherlands
  • VWR International BVBA, Haasrode Researchpark 2020 3001 Leuven Belgium
  • Wilmar Oleochemicals B.V., Merseyweg 10, Botlek 3197KG Rotterdam Netherlands
  • WSP UK Ltd (OR1), The Victoria 150-182 The Quays M50 3SP Salford Greater Manchester United Kingdom
  • [Confidential], [Confidential]
  • Arcerion GmbH, Gabrielenstr. 15 80636 München Germany
  • Borealis AG, Wagramerstrasse 17-19 1220 Wien Austria
  • CSI-OR003, Pentlands Science Park Penicuik EH26 0PZ Edinburgh United Kingdom
  • ExxonMobil Chemical Ltd., Ermyn Way ExxonMobil House KT22 8UX Surrey Leatherhead United Kingdom
  • HML Europe BV, De Haal 82 1511 AT Oostzaan Netherlands
  • momaja s.r.o, Karolinská 650/1 186 00 Prague 8 Czech Republic
  • OMV PETROM S.A., 22 Coralilor Street (“Petrom City”) Sector 1 013329 Bucharest Romania
  • PETROBRAS EUROPE LIMITED., 9th Floor, 1 Angel Court EC2R 7HJ London United Kingdom
  • PETROBRAS GLOBAL TRADING BV - PGT BV, Weena 762 - 9th Floor, First Rotterdam 3014 DA Rotterdam Netherlands
  • Raffineria di Milazzo S.C.p.A., Contrada Mangiavacca 98057 Milazzo (ME) Italy
  • REACH24H CONSULTING GROUP, Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland
  • REACHLaw Ltd., Vänrikinkuja 3 JK 21 02600 Espoo Finland
  • Trammo SARL, 23 Rue Balzac 75008 Paris France
  • TÜV SÜD Industrie Service GmbH, Westendstraße 199 80686 München Germany
  • Vitol Chemicals BV, K.P. van der Mandelelaan 130 3062 MB Rotterdam Netherlands

Substance names and other identifiers

alcool metilico (it)
C&L Inventory
alkohol metylowy (pl)
C&L Inventory
metanol (es)
C&L Inventory
metanoli (fi)
C&L Inventory
metanolis (lt)
C&L Inventory
metanolo (it)
C&L Inventory
metanols (lv)
C&L Inventory
Metanool (et)
C&L Inventory
methanol (da)
C&L Inventory
méthanol (fr)
C&L Inventory
μεθανόλη μεθυλική αλκοόλ (el)
C&L Inventory
метанол (bg)
C&L Inventory
ECHA-8600dbe1-6174-49ec-b025-9cd03d318e49
C&L Inventory
Mathanol
C&L Inventory
methan-1-ol
C&L Inventory
methanol_Oman trading international Europe BV
Registration dossier
Methyl Alcohol
C&L Inventory, Registration dossier
methylacohol
C&L Inventory
monohydroxymethane
C&L Inventory
not applicable
Registration dossier
Renewable Methanol
Registration dossier
Torque Seal Green
C&L Inventory
UPV11
C&L Inventory
12120490 Methanol
Registration dossier
alcol metilico
C&L Inventory
AZEOsolve
Registration dossier
Carbinol
Registration dossier
CR12
Registration dossier
Dow Corning Raw Material No. 2237296 METHYL ALCOHOL 99.85%, METHANOL (EUROPE)
Registration dossier
EUROALIMENT 40
Registration dossier
industrial methanol
Registration dossier
MeOH
Registration dossier
Methanol (8 CI, 9 CI)
Registration dossier
Methanol (8CI, 9CI)
Registration dossier
Methanol (8Cl, 9Cl)
Registration dossier
Methanol for Biodiesel
Registration dossier
Methanol for technical use
Registration dossier
Methanol Stripping
Registration dossier
Methanol technical
Registration dossier
Methanol(8Cl, 9Cl)
Registration dossier
methanol, bio- methanol
Registration dossier
Methyl hydroxide
Registration dossier
TEC SOL-2
Registration dossier
technical methanol
Registration dossier
1173023-83-0
Deleted CAS number
Other
54841-71-3
Deleted CAS number
Other
603-001-00-X
Index number
C&L Inventory
67-56-1
CAS number
EC Inventory, C&L Inventory, Substance Evaluation - CoRAP, Registration dossier, REACH pre-registration, Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [1]
C Odour
Pungent (100%) [1]
C Substance type
Organic (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 2 studies submitted
  • 1 study processed
R Melting / freezing point
-97.8 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
-97.8 °C

Boiling point

Study results
  • 2 studies submitted
  • 1 study processed
R Boiling point
64.7 °C @ 101.3 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
64.7 °C

Density

Study results
  • 3 studies submitted
  • 1 study processed
R Relative density
0.79 - 0.8 @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
0.79

Vapour pressure

Study results
  • 2 studies submitted
  • 1 study processed
R Vapour pressure
16.927 kPa @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
16.927 kPa @ 25 °C

Partition coefficient

Study results
  • 2 studies submitted
  • 1 study processed
R Log Pow
-0.77 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
-0.77 @ 20 °C

Water solubility

Study results
  • 2 studies submitted
  • 1 study processed
R Water solubility (mass/vol.)
1 000 g/L @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 2 studies submitted
  • 1 study processed
R Flash point
9.7 °C @ 101.3 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
9.7 °C

Auto flammability

Study results
  • 3 studies submitted
  • 1 study processed
R Autoflammability / self-ignition
455 °C @ 101.3 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
455 °C

Flammability

Study results
  • 7 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 4
Sci. unjustified 3
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Flammable (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
Non oxidising (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 2 studies submitted
  • 1 study processed
R dynamic viscosity (in mPa s)
0.544 - 0.59 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 1 study submitted
  • 1 study processed
R Dissipation half life (DT50)
17.2 days [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Half life in air
17 days

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 5 studies submitted
  • 4 studies processed
R BOD5
1.067 - 1.236 g O2/g test material [2]
C Interpretation of results
Readily biodegradable (100%) [4]

Type of Study provided
Studies with data
Key study 4
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Readily biodegradable (100%)

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Henry's law constant
0.461 Pa.m³.mol-1 @ 20 °C

Distribution modelling

Study results
  • 2 studies submitted
  • 2 studies processed
% Distribution in Media:
R Air 12.5 - 73.3 % [2]
R Water 15.6 - 87.5 % [2]
R Soil 0 - 11.1 % [2]
R Sediment 0 - 0.02 % [2]
R Suspended sediment 0 % [1]
R Biota 0 % [1]
R Aerosol 0 % [1]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 20.8 mg/L (1)
Intermittent releases (freshwater) 1.54 g/L (1)
Marine water 2.08 mg/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 100 mg/L (1)
Sediment (freshwater) 77 mg/kg sediment dw (1)
Sediment (marine water) 7.7 mg/kg sediment dw (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 100 mg/kg soil dw (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 13 studies submitted
  • 1 study processed
P/RResults
LC50 (4 days) 15.4 g/L [1]
EC50 (4 days) 12.7 g/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 11
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
LC50 for freshwater fish
15.4 g/L

Long–term toxicity to fish

Study results
  • 6 studies submitted
  • 2 studies processed
P/RResults
NOEC (28 days) 446.7 mg/L [1]
NOEC (8.333 days) 7.9 - 158 g/L [6]
LOEC (8.333 days) 7.9 - 39.505 g/L [6]
EC50 (8.333 days) 9.164 - 14.536 g/L [3]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 3 1
Other 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 / LC10 or NOEC for freshwater fish
450 mg/L

Short–term toxicity to aquatic invertebrates

Study results
  • 7 studies submitted
  • 1 study processed
P/RResults
EC50 (4 days) 18.26 g/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 6
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 5 studies submitted
  • 1 study processed
P/RResults
NOEC (21 days) 208 mg/L [1]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 3 1
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 / LC10 or NOEC for freshwater invertebrates
208 mg/L

Toxicity to aquatic algae and cyanobacteria

Study results
  • 4 studies submitted
  • 1 study processed
P/RResults
EC50 (4 days) 22 g/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
22 g/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 6 studies submitted
  • 1 study processed
P/RResults
IC50 (3 h) 1 g/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 5
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for microorganisms
20 g/L

Sediment toxicity

Study results
  • 3 studies submitted
  • 2 studies processed
P/RResults
EC50 (3 min) 71.7 g/L [1]
LC50 (4 days) 54.89 g/L [1]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EC50 (63 days) 26.646 g/kg soil dw [1]
EC50 (35 days) 17.199 g/kg soil dw [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Long-term EC10 / LC10 / NOEC
10 g/kg soil dw

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (28 days) 10 g/kg soil dw [1]
EC50 (28 days) 5.683 g/kg soil dw [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Long-term EC10 / LC10 / NOEC
1 g/kg soil dw

Toxicity to terrestrial plants

Study results
  • 8 studies submitted
  • 3 studies processed
P/RResults
NOEC (21 days) 20 g/kg soil dw [1]
EC50 (21 days) 15.492 g/kg soil dw [1]
EC50 (14 days) 15.492 g/kg soil dw [1]
EC25 (21 days) 1.808 - 12.202 g/kg soil dw [8]
EC25 (14 days) 2.823 - 5 752 mg/kg soil dw [4]

Type of Study provided
Studies with data
Key study 3
Supporting study 3
Weight of evidence
Other 2
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Long-term EC10 / LC10 / NOEC
1.555 g/kg soil dw

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 130 mg/m³ acute toxicity
Acute /short term: (DNEL) 130 mg/m³ acute toxicity
Local Effects
Long-term: (DNEL) 130 mg/m³ acute toxicity
Acute /short term: (DNEL) 130 mg/m³ acute toxicity
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 20 mg/kg bw/day acute toxicity
Acute /short term: (DNEL) 20 mg/kg bw/day acute toxicity
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 26 mg/m³ acute toxicity
Acute /short term: (DNEL) 26 mg/m³ acute toxicity
Local Effects
Long-term: (DNEL) 26 mg/m³ acute toxicity
Acute /short term: (DNEL) 26 mg/m³ acute toxicity
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 4 mg/kg bw/day acute toxicity
Acute /short term: (DNEL) 4 mg/kg bw/day acute toxicity
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 4 mg/kg bw/day acute toxicity
Acute /short term: (DNEL) 4 mg/kg bw/day acute toxicity
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 23 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence 23
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation potential:
No bioaccumulation potential
Absorption values
Oral: 100 %
Inhalation: 60 %

Acute toxicity

Study results
oral
  • 5 studies submitted
  • 5 studies processed
P/RResults
LD50 1 187 - 2 769 mg/kg bw (rat) [1]
LD0 2 528 mg/kg bw (rat) [1]
LD50 6 000 - 9 000 mg/kg bw (monkey) [2]
LD50 5 000 mg/kg bw (pig) [1]

Type of Study provided
oral
Studies with data
Key study
Supporting study
Weight of evidence 5
Other
Data waiving
no waivers
inhalation
  • 7 studies submitted
  • 5 studies processed
P/RResults
LC50 (6 h) 82.1 - 92.6 mg/L air (rat) [3]
LC50 (4 h) 115.9 - 130.7 mg/L air (rat) [3]
LC50 (2.233 h) 79.43 mg/L air (mouse) [1]
LC50 (6 h) 43.68 mg/L air (cat) [1]
LC50 (4.5 h) 85.41 mg/L air (cat) [1]

inhalation
Studies with data
Key study
Supporting study
Weight of evidence 7
Other
Data waiving
no waivers
dermal
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

dermal
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
other routes
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

other routes
Studies with data
Key study
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
Adverse effect observed LD50 1 187 mg/kg bw
Inhalation route:
Adverse effect observed LC50 43 700 mg/m³
Dermal route:
Adverse effect observed LD50 17 100 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 2 studies submitted
  • 1 study processed
P/RResults
LOAEL (monkey): 2 340 mg/kg bw/day [1]

Type of Study provided
Study data: oral
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
Study data: inhalation
  • 11 studies submitted
  • 10 studies processed
P/RResults
NOAEL (rat): 13.3 mg/L air [1]
NOAEC (rat): 260 - 6 660 mg/m³ air [4]
NOAEC (mouse): 1.3 mg/L air [1]
NOAEC (monkey): 13 - 1 300 mg/m³ air [2]
NOEC (rat): 130 mg/m³ air [1]

Study data: inhalation
Studies with data
Key study
Supporting study
Weight of evidence 11
Other
Data waiving
no waivers
Study data: dermal
  • 0 studies submitted
  • 0 studies processed

No data available

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route - systemic effects:
Adverse effect observed LOAEL 2 340 mg/kg bw/day (subacute, monkey)
Inhalation route - systemic effects:
No adverse effect observed NOAEC 13 mg/m³ (chronic, monkey)

Genetic toxicity

Study results
Study data: in vitro
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study
Supporting study
Weight of evidence 8
Other
Data waiving
no waivers
Study data: in vivo
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study
Supporting study
Weight of evidence 7
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Toxicity - InVitro
Adverse effect observed (positive)
Toxicity - InVivo
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 4 1
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Inhalation route:
No adverse effect observed NOAEC 1 300 mg/m³ (chronic, mouse)

Toxicity to reproduction

Study results
Study data: reproduction
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
no waivers
Study data: developmental
  • 51 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study
Supporting study
Weight of evidence 46 4 1
Other
Data waiving
no waivers
Study data: other studies
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Effect on fertility
Oral route:
No adverse effect observed NOAEL 1 000 mg/kg bw/day (subchronic, mouse)
Inhalation route:
No adverse effect observed NOAEC 1 300 mg/m³ (chronic, rat)
Effect on developmental toxicity
Oral route:
Adverse effect observed LOAEL 1 700 mg/kg bw/day (subchronic, mouse)
Inhalation route:
Adverse effect observed NOAEC 1 330 mg/m³ (subacute, rat)

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant