Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
203-213-9
CAS no.:
104-55-2
Index number:
Molecular formula:
C9H8O
SMILES:
O=C\C=C\C1=CC=CC=C1
InChI:
InChI=1S/C9H8O/c10-8-4-7-9-5-2-1-3-6-9/h1-8H/b7-4+
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
8
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Warning! According to the classification provided by companies to ECHA in REACH registrations this substance causes serious eye irritation, is harmful to aquatic life with long lasting effects, is harmful in contact with skin, causes skin irritation and may cause an allergic skin reaction.

Breakdown of all 2757 C&L notifications submitted to ECHA

Skin Irrit. 2 H315
Eye Irrit. 2 H319
Skin Sens. 1 H317
Acute Tox. 4 H312
Skin Sens. 1A H317
STOT SE 3 H335
Acute Tox. 4 H302
Aquatic Chronic 3 H412
Skin Sens. 1B H317
Aquatic Acute 1 H400
Not Classified
Acute Tox. 3 H311
Eye Dam. 1 H318
Acute Tox. 4 H332
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://chesar.echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://chesar.echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://chesar.echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • Ss
There is broad agreement in that a majority of data submitters agree this substance is Skin sensitising (100% of REACH registrations).

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 10 active registrations under REACH, 1 Joint Submission(s) and 1 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
This substance is approved for use as a Biocidal Active Substance
Biocidal Products:
There are 0 authorised Biocidal Product(s) that use this substance as an active ingredient

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 1 000 - 10 000 tonnes per year.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: air care products, perfumes and fragrances, polishes and waxes, washing & cleaning products, cosmetics and personal care products, pharmaceuticals and biocides (e.g. disinfectants, pest control products).

Other release to the environment of this substance is likely to occur from: indoor use as processing aid and outdoor use as processing aid.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

Other release to the environment of this substance is likely to occur from: indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints).

This substance is intended to be released from scented: clothes, eraser, toys, paper products and CDs.

This substance is used in the following products: cosmetics and personal care products, perfumes and fragrances, polishes and waxes, washing & cleaning products and pharmaceuticals.

This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, roller or brushing applications, non-industrial spraying, hand mixing with intimate contact only with personal protective equipment available, batch processing in synthesis or formulation with opportunity for exposure and treatment of articles by dipping and pouring.

Other release to the environment of this substance is likely to occur from: indoor use as processing aid and outdoor use as processing aid.

This substance is used in the following products: air care products, biocides (e.g. disinfectants, pest control products), metal surface treatment products, laboratory chemicals, plant protection products, perfumes and fragrances, pharmaceuticals, polishes and waxes, washing & cleaning products and cosmetics and personal care products. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, mixing in open batch processes, transfer of substance into small containers, laboratory work, hand mixing with intimate contact only with personal protective equipment available and production of mixtures or articles by tabletting, compression, extrusion or pelletisation.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

This substance is used in the following products: perfumes and fragrances, laboratory chemicals, pharmaceuticals and cosmetics and personal care products. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: formulation of mixtures and/or re-packaging and health services. This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure, closed batch processing in synthesis or formulation, laboratory work and transfer of chemicals.

Release to the environment of this substance can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), in processing aids at industrial sites, of substances in closed systems with minimal release and as processing aid.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, transfer of substance into small containers, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure and mixing in open batch processes.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: do not get in eyes, on skin, or on clothing; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing. If swallowed: call a poison center or doctor/physician if you feel unwell. If on skin: wash with soap and water.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • ChampionX Europe B.V., Oude Rhijnhofweg 17 NL-2342BB Oegstgeest Oegstgeest Netherlands
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Lanxess India OR, Kennedyplatz 1 50569 Cologne NRW Germany
  • Luxcontrol S.A. (OR66), 1, Avenue des Terres Rouges 4331 Esch/Alzette Luxembourg
  • MINASOLVE S.A.S, 145 Chemin des Lilas 59310 Beuvry la Foret France
  • Penman Consulting bvba 09, Avenue des Arts 10 B-1210 Brussels Belgium
  • Prakash Chemicals Europe B.V., Lotte Stam Beesetr 136 3066 HB Rotterdam The Netherlands Netherlands
  • Sensient Fragrances, S.A.U., Crta. Armilla Km 2,5 18100 Armilla Granada Spain
  • Sustainability Support Services (Europe) AB, Markaskälsvägen 6 22647 Lund Sweden

Substance names and other identifiers

2-Propenal, 3-phenyl-
Other
3-Fenylpropenal
Other
3-Phenyl-2-propen-1-al
Other
3-Phenyl-2-propenal
Other
3-Phenyl-2-propenaldehyde
Other
3-Phenylacrolein
Other
3-Phenylacrylaldehyde
Other
3-Phenylpropenal
Other
Abion CA
Other
Acrolein, 3-phenyl-
Other
Aldehyd skoricovy
Other
Benzylideneacetaldehyde
Other
beta-Phenylcrolein
Other
Cassia aldehyde
Other
Cinnamal
Other
Cinnamaldehyde
EC Inventory, REACH pre-registration, Other
Cinnamaldehyde/3-phenyl-propen-2-al(Cinnamic aldehyde)
Biocidal active substances
Cinnamic aldehyde
Other
Cinnamic aldehyde (natural)
Other
Cinnamyl aldehyde
Other
Cinnemaldehyde
Other
Hefty Dog and Cat Repellent
Other
Phenylacrolein
Other
Zimtaldehyde
Other
3-fenüülprop-2-enaal (kaneelaldehüüd) (et)
Biocidal active substances
Aldehyd cynamonowy/3-fenylo-propen-2-al (aldehyd cynamonowy) (pl)
Biocidal active substances
Cihnamaldehid/3-fenil-propen-2-al (cimetov aldehid) (sl)
Biocidal active substances
Cinamaldehid/3-fenil-propen-2-al (cimetni aldehid) (hr)
Biocidal active substances
Cinamaldehidă/3-fenil-propen-2-al (Aldehidă cinamică) (ro)
Biocidal active substances
cinamaldehyd/(E)-3-fenylpropenál (škoricový aldehyd) (sk)
Biocidal active substances
Cinamaldehído/3-fenil-propen-2-al (aldehído cinámico) (es)
Biocidal active substances
Cinamaldeído/3-fenilpropen-2-al (aldeído cinâmico) (pt)
Biocidal active substances
Cinamono aldehidas/3-fenil-propen-2-alis (cinamono aldehidas) (lt)
Biocidal active substances
Cinnamaldehyd/3-fenyl-propen-2-al (Kanelaldehyd) (sv)
Biocidal active substances
cinnamaldehyd/3-fenylprop-2-enal (cinnamaldehyd) (cs)
Biocidal active substances
Cinnamaldehyde/3-fenylpropeen-2-al (kaneelaldehyde) (nl)
Biocidal active substances
Cinnamaldehyde/3-phenyl-propen-2-al (Cinnamic aldehyde) (mt)
Biocidal active substances
Cinnamaldeide/3-fenil-propen-2-ale (Aldeide cinnamica) (it)
Biocidal active substances
Cinnamaldéhyde/3-phényl-propen-2-al (aldéhyde cinnamique) (fr)
Biocidal active substances
Fahéjaldehid/3-fenilpropén-2-al (Cinammaldehid) (hu)
Biocidal active substances
kanelaldehyd/3-phenylpropen-2-al (da)
Biocidal active substances
Kanelialdehydi/3-fenyyli-propeeni-2-al (kanelialdehydi) (fi)
Biocidal active substances
Kanēļaldehīds/3-fenil-propēn-2-āls (kanēļskābes aldehīds) (lv)
Biocidal active substances
Zimtaldehyd/3-Phenyl-propen-2-al (Cinnamaldehyd) (de)
Biocidal active substances
Κινναμωμαλδεΰδη/3-φαινυλο-προπεν-2-άλη (κινναμωμική αλδεΰδη) (el)
Biocidal active substances
Цинамалдехид/3-фенилпропен-2-ал (канелен алдехид) (bg)
Biocidal active substances
(2E)-3-PHENYLPROP-2-ENAL
C&L Inventory, Registration dossier, Other
(E)-3-phenylprop-2-enal
C&L Inventory, Other
3-phenyl-prop-2-enal
C&L Inventory
3-Phenylprop-2-enal
C&L Inventory, Registration dossier
3-Phenylpropenol aldehyde
C&L Inventory
aldehyde cinnamique
C&L Inventory
cinnamaldehyd
C&L Inventory
E-3-phenylprop-2-enal
C&L Inventory
Fragrance oil
C&L Inventory
undec-10-enal
C&L Inventory
Cinnamaldehid
C&L Inventory
Kalama® Cinnamic Aldehyde FCC
Registration dossier
104-55-2
CAS number
EC Inventory, C&L Inventory, Biocidal active substances, Registration dossier, REACH pre-registration, Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 4 studies submitted
  • 2 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [2]
C Form
Liquid (100%) [1]
C Odour
Other (100%) [1]
C Substance type
Organic (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Physical state at 20°C and 1013 hPa
Liquid (100%)
Form
Liquid (100%)
Colour
colourless (100%)
Colour Intensity
light (100%)

Melting/freezing point

Study results
  • 6 studies submitted
  • 2 studies processed
R Melting / freezing point
-18 - -7.5 °C @ 96.99 kPa [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 3 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Melting / freezing point at 101 325 Pa
-18 - -7.5 °C

Boiling point

Study results
  • 11 studies submitted
  • 2 studies processed
R Boiling point
250 - 252.4 °C @ 96 - 96.99 kPa [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 6 3
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Boiling point at 101 325 Pa
250 - 266.4 °C

Density

Study results
  • 9 studies submitted
  • 2 studies processed
R Bulk density
0.944 g/cm³ @ 27 °C [1]
R Density
1.041 g/cm³ @ 20 °C [1]

Type of Study provided
Studies with data
Key study 2
Supporting study 7
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Relative density at 20°C
0.699 - 1.041

Vapour pressure

Study results
  • 7 studies submitted
  • 2 studies processed
R Vapour pressure
3.853 - 3.853 Pa @ 25 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 1 3 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Vapour pressure
3.853 Pa @ 25 °C

Partition coefficient

Study results
  • 8 studies submitted
  • 2 studies processed
R Log Pow
1.83 - 2.107 @ 25 - 27.5 °C and pH 3.76 [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 4 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Log Kow (Log Pow)
1.83 - 2.1 @ 25 - 27 °C

Water solubility

Study results
  • 10 studies submitted
  • 2 studies processed
R Water solubility (mass/vol.)
2.865 - 10 g/L @ 25 - 27 °C and pH 3.55 [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 5 3
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Water solubility
2.865 - 10 g/L @ 25 - 27 °C

Solubility in organic solvents / fat solubility

Study results
  • 3 studies submitted
  • 1 study processed
R Ethanol
4 g/L @ 27 °C [1]

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Surface tension

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Surface tension at 20 °C
39 - 45.3 mN/m

Flash point

Study results
  • 10 studies submitted
  • 2 studies processed
R Flash point
105 - 125 °C @ 96.6 - 96.83 kPa [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 7 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Flash point at 101 325 Pa
105 - 131.11 °C

Auto flammability

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 3 studies submitted
  • 1 study processed
C Interpretation of results
Non flammable (100%) [1]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Flammability
Not classified (50%), Non flammable (50%)

Explosiveness

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oxidising
Yes (50%), Non oxidising (50%)

Oxidation reduction potential

Data not provided by the registrant

pH

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Dissociation constant

Study results
  • 2 studies submitted
  • 1 study processed
R Dissociation constant
0 @ 27 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
R Summaries
  • 2 summaries submitted
  • 1 summary processed
pKa at 20 °C
0

Viscosity

Study results
  • 2 studies submitted
  • 2 studies processed
R dynamic viscosity (in mPa s)
12.83 - 22.12 [3]
R kinematic viscosity (in mm²/s)
17.29 - 21.25 [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Static viscosity at 20 °C
21.25 mm²/s
Dynamic viscosity at 20 °C
9.5 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
R Summaries
  • 2 summaries submitted
  • 1 summary processed
Half-life for hydrolysis
3.171 h @ 25 °C

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 9 studies submitted
  • 6 studies processed
R BOD5
0.635 mg O2/g test material [1]
R ThOD
2.542 mg O2/g test material [1]
C Interpretation of results
Readily biodegradable (100%) [5]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 1
Weight of evidence 6
Other
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Biodegradation in water
Readily biodegradable (100%)

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Half-life in freshwater
15 days @ 25 °C
Half-life in freshwater sediment
4.5 months @ 25 °C

Biodegradation in soil

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Half-life in soil
30 days @ 25 °C

Bioaccumulation: aquatic / sediment

Study results
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1 1
Supporting study 4
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
R Summaries
  • 2 summaries submitted
  • 1 summary processed
Bioaccumulation Factor (BCF) - dimensionless
8

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 5 studies submitted
  • 1 study processed
R log Koc
1.958 dimensionless @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1 1
Supporting study 1 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Koc at 20°C
36.982 - 90.78

Henrys law constant (H)

Study results
  • 3 studies submitted
  • 1 study processed
R H - dimensionless
0 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Henry's law constant
0 Pa.m³.mol-1 @ 25 °C

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 2 summaries submitted
  • 2 summaries processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 3.21 - 1 004 µg/L (2)
Intermittent releases (freshwater) 32.1 - 1 004 µg/L (2)
Marine water 321 - 100 400 ng/L (2)
Intermittent releases (marine water) 3.21 µg/L (1)
Sewage treatment plant (STP) 13.119 mg/L (1)
Sediment (freshwater) 40.7 - 159 185.14 µg/kg sediment dw (2)
Sediment (marine water) 4.07 - 159 185.14 µg/kg sediment dw (2)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 6.26 - 56 084.725 µg/kg soil dw (2)
Hazard for Predators
Secondary poisoning 333.333 ng/kg food (1)

Short–term toxicity to fish

Study results
  • 10 studies submitted
  • 2 studies processed
P/RResults
LC50 (4 days) 3.9 - 105.764 mg/L [2]
LC50 (24 h) 2.35 mg/L [1]
LC0 (24 h) 1.41 mg/L [1]
LC100 (4 days) 5.5 mg/L [1]
LC100 (24 h) 3.93 mg/L [1]

Type of Study provided
Studies with data
Key study 1 1
Supporting study 7 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
LC50 for freshwater fish
3.9 - 105.76 mg/L

Long–term toxicity to fish

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
NOEC (28 days) 15.159 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
R Summaries
  • 2 summaries submitted
  • 1 summary processed
EC10 / LC10 or NOEC for freshwater fish
15.159 mg/L

Short–term toxicity to aquatic invertebrates

Study results
  • 5 studies submitted
  • 4 studies processed
P/RResults
EC50 (48 h) 3.21 - 119.558 mg/L [5]
EC100 (48 h) 30 mg/L [1]
NOEC (48 h) 1.91 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence 3
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
EC50 / LC50 for freshwater invertebrates
3.21 - 119.56 mg/L

Long–term toxicity to aquatic invertebrates

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EC50 (21 days) 402 µg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 6 studies submitted
  • 4 studies processed
P/RResults
EC50 (72 h) 4.07 - 31.6 mg/L [5]
NOEC (72 h) 2 - 37.231 mg/L [2]

Type of Study provided
Studies with data
Key study 1 1
Supporting study 1
Weight of evidence 3
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
EC50 for freshwater algae
31.6 mg/L
EC10 or NOEC for freshwater algae
37.23 mg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 4 studies submitted
  • 2 studies processed
P/RResults
EC50 (3 h) 71 mg/L [1]
IC50 (48 h) 131.195 mg/L [1]

Type of Study provided
Studies with data
Key study 1 1
Supporting study 1 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 1 summary processed
EC50 for microorganisms
71 mg/L

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 4 studies submitted
  • 1 study processed
P/RResults
LC50 (14 days) 895.927 mg/kg soil dw [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
R Summaries
  • 2 summaries submitted
  • 1 summary processed
Short-term EC50 / LC50
895.92 mg/kg soil dw

Toxicity to terrestrial arthropods

Study results
  • 5 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 4 studies submitted
  • 1 study processed
P/RResults
NOEC (14 days) 1.5 mg/kg soil ww [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 2.204 mg/m³ repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 1.17 mg/kg bw/day developmental toxicity / teratogenicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
Hazard unknown (no further information necessary)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 543.478 µg/m³ repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 417 µg/kg bw/day developmental toxicity / teratogenicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 417 µg/kg bw/day developmental toxicity / teratogenicity
Acute /short term: No hazard identified
EYE Exposure
Hazard unknown (no further information necessary)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation potential:
No bioaccumulation potential

Acute toxicity

Study results
oral
  • 8 studies submitted
  • 2 studies processed
P/RResults
LD50 2 220 mg/kg bw (rat) [1]
LD50 3 400 mg/kg bw (guinea pig) [1]
M/CInterpretations of results
Not classified [1]

Type of Study provided
oral
Studies with data
Key study 2
Supporting study 6
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 3 studies submitted
  • 1 study processed
P/RResults
LC50 (4 h) 68.889 ppm (rat) [1]
M/CInterpretations of results
Not classified [1]

inhalation
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
dermal
  • 6 studies submitted
  • 2 studies processed
P/RResults
LD50 2 000 mg/kg bw (rat) [1]
LD50 1 260 mg/kg bw (rabbit) [1]
M/CInterpretations of results
Toxicity Category IV [1]

dermal
Studies with data
Key study 2
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oral route:
No adverse effect observed LD50 3 400 mg/kg bw
Dermal route:
Adverse effect observed LD50 1 260 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 3
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Study data: eye
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 3
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin
Adverse effect observed (irritating)
Eye
Adverse effect observed (irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 10 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2
Supporting study 6 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin sensitisation
Adverse effect observed (sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 18 studies submitted
  • 3 studies processed
P/RResults
NOAEL (rat): 125 - 200 mg/kg bw/day [2]
NOAEL (mouse): 656 mg/kg bw/day [1]
LOAEL (mouse): 1 310 mg/kg bw/day [1]

Type of Study provided
Study data: oral
Studies with data
Key study 2
Supporting study 15
Weight of evidence 1
Other
Data waiving
no waivers
Study data: inhalation
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Study data: dermal
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oral route - systemic effects:
No adverse effect observed NOAEL 656 mg/kg bw/day (subacute, mouse)
Dermal route - systemic effects:
No adverse effect observed LOAEL 750 mg/kg bw/day (subchronic, mouse)

Genetic toxicity

Study results
Study data: in vitro
  • 18 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 4 1
Supporting study 12
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: in vivo
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Toxicity - InVitro
No adverse effect observed (negative)
Toxicity - InVivo
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study 3
Weight of evidence 1
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed NOAEL 235 mg/kg bw/day (subacute, rat)

Toxicity to reproduction

Study results
Study data: reproduction
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study 2
Weight of evidence 4
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Study data: developmental
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: other studies
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence 1
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Effect on fertility
Oral route:
No adverse effect observed NOAEL 556 mg/kg bw/day (subchronic, rat)
Effect on developmental toxicity
Oral route:
No adverse effect observed NOAEL 250 mg/kg bw/day (subacute, rat)

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant