Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
215-647-6
CAS no.:
1336-21-6
Index number:
Molecular formula:
H5NO
SMILES:
InChI:
Type of substance:
Mono constituent substance
Origin:
Inorganic
Registered compositions:
1
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance causes severe skin burns and eye damage and is very toxic to aquatic life.

Breakdown of all 6156 C&L notifications submitted to ECHA

Skin Corr. 1B H314 Harmonised Classification
Aquatic Acute 1 H400 Harmonised Classification
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://chesar.echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://chesar.echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://chesar.echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • M
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Mutagenic (0.02% of CLP notifications).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 1 active registrations under REACH, 0 Joint Submission(s) and 1 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Industrial accident prevention and reporting requirements have been established for this substance.
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, for intermediate use only.

This substance is used at industrial sites and in manufacturing.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the types of manufacture using this substance.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

ECHA has no public registered data on the types of manufacture using this substance.

This substance is used in the following activities or processes at workplace: closed batch processing in synthesis or formulation.

Release to the environment of this substance can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates).

This substance is used in the following activities or processes at workplace: closed batch processing in synthesis or formulation.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: do not breathe the dust, fume, gas, mist, vapours or spray; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: Collect spillage. If swallowed: rinse mouth. Do not induce vomiting. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Chemische Fabrik Karl Bucher GmbH, An der Guenz 1 89367 Waldstetten Germany

Substance names and other identifiers

ammonia
EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, Workplace Signs - minimum requirements & signs on containers and pipes
ammonia ....%
C&L Inventory, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, General Product Safety Directive - Hazardous Substances, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
Ammonia, aqueous solution
EC Inventory
ammonia, aqueous solution
REACH pre-registration
Ammonium hydroxide
Cosmetic Products Regulation, Annex III - Restricted Substances, FCM and Articles Regulation, Annex I - Authorised Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use
Ammonium hydroxide ((NH4)(OH))
Other
... % amonjaks (lv)
C&L Inventory
ammoniac …% (fr)
C&L Inventory
ammoniaca ....% (it)
C&L Inventory
ammoniak ....% (da)
C&L Inventory
Ammoniak ....% (de)
C&L Inventory
ammoniak ....% (nl)
C&L Inventory
ammoniakki ....% (fi)
C&L Inventory
ammoniakkløsning ... % (no)
C&L Inventory
ammoniaklösning ....% (sv)
C&L Inventory
Ammonium …% (et)
C&L Inventory
ammónia ...% (oldat) (hu)
C&L Inventory
amoniac ....% (ro)
C&L Inventory
amoniaco ....% (es)
C&L Inventory
amoniak ….% (sk)
C&L Inventory
amoniak, raztopina...% (sl)
C&L Inventory
amoniak, roztok ...% (cs)
C&L Inventory
amoniak, roztwór ... % (pl)
C&L Inventory
amoniakas….% (lt)
C&L Inventory
amonijak ....% (hr)
C&L Inventory
amoníaco ....% (pt)
C&L Inventory
αμμωνία ....% (el)
C&L Inventory
амоняк,....% (bg)
C&L Inventory
Ammonium hydroxide ((NH4)(OH))
Other
amm0nia
C&L Inventory
ammnia
C&L Inventory
Ammonia
C&L Inventory
ammonia ... %
C&L Inventory
ammonia ....%
C&L Inventory
ammonia 15 %
C&L Inventory
ammonia 25%
C&L Inventory
AMMONIA AQUEOUS
C&L Inventory
Ammonia Aqueous 24.5%-24.9%
C&L Inventory
AMMONIA AQUEOUS SOLUTION
C&L Inventory
Ammonia solution
C&L Inventory
Ammonia Solution (28% in Water) [for General Organic Chemistry]
C&L Inventory
Ammonia solution 25%
C&L Inventory
ammonia water
C&L Inventory
Ammonia waterAmmonia aqueousAquammonia
C&L Inventory
ammonia ….%
C&L Inventory
Ammonia, Aqueous
C&L Inventory
Ammonia, Aqueous Solution
C&L Inventory
Ammonia, aqueous solution
C&L Inventory
Ammonia...%
C&L Inventory
ammonia....%
C&L Inventory
ammoniak
C&L Inventory
AMMONIAQUE
C&L Inventory
Ammonium chloride
C&L Inventory
ammonium hydoxide
C&L Inventory
AMMONIUM HYDROXIDE
C&L Inventory, Registration dossier
Ammonium hydroxide
C&L Inventory, Registration dossier
AMMONIUM HYDROXIDE ((NH4)(OH))
C&L Inventory
AMMONIUM HYDROXIDE 25% SOLUTION IN WATER
C&L Inventory
Ammonium hydroxyde
C&L Inventory
AMMONIUM HYDROXYDE (20-25% SOLUTION)
C&L Inventory
ammonium oxidanide
C&L Inventory
Amoniaco
C&L Inventory
Amoniak, roztok
C&L Inventory
Aqua ammonia
C&L Inventory
aqueous ammonia solution
C&L Inventory
Aqueous solution of ammonium hydroxide
C&L Inventory
Aqueous solution of ammonum
C&L Inventory
azane
C&L Inventory
Azane, aqueous solution
C&L Inventory
azanium hydroxide
C&L Inventory
azanium;hydroxide
C&L Inventory, Other
Hidróxido de amonio
C&L Inventory
HYDROXIDE, AMMONIUM
C&L Inventory
hydroxyazanium
C&L Inventory
Reaction mass of 7664-41-7 and 7732-18-5
C&L Inventory
Reaction mass of ammonia, anhydrous and water
C&L Inventory
Ammoniakwasser <25%
C&L Inventory
007-001-01-2
Index number
C&L Inventory
1252662-61-5
CAS number
Other
1252662-61-5
Deleted CAS number
Other
125888-87-1
CAS number
Other
125888-87-1
Deleted CAS number
Other
1269620-59-8
CAS number
Other
1269620-59-8
Deleted CAS number
Other
1313584-68-7
CAS number
Other
1313584-68-7
Deleted CAS number
Other
132103-60-7
CAS number
Other
132103-60-7
Deleted CAS number
Other
1336-21-6
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex III - Restricted Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, FCM and Articles Regulation, Annex I - Authorised Substances, General Product Safety Directive - Hazardous Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
1398052-85-1
CAS number
Other
1398052-85-1
Deleted CAS number
Other
16393-49-0
CAS number
Other
16393-49-0
Deleted CAS number
Other
178115-93-0
CAS number
Other
178115-93-0
Deleted CAS number
Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Data not provided by the registrant

Melting/freezing point

Data not provided by the registrant

Boiling point

Data not provided by the registrant

Density

Data not provided by the registrant

Vapour pressure

Data not provided by the registrant

Partition coefficient

Data not provided by the registrant

Water solubility

Data not provided by the registrant

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Data not provided by the registrant

Flash point

Data not provided by the registrant

Auto flammability

Data not provided by the registrant

Flammability

Data not provided by the registrant

Explosiveness

Data not provided by the registrant

Oxidising

Data not provided by the registrant

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Data not provided by the registrant

Viscosity

Data not provided by the registrant

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Data not provided by the registrant

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Data not provided by the registrant

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Data not provided by the registrant

Bioaccumulation: aquatic / sediment

Data not provided by the registrant

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Data not provided by the registrant

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

Data not provided by the registrant

Short–term toxicity to fish

Data not provided by the registrant

Long–term toxicity to fish

Data not provided by the registrant

Short–term toxicity to aquatic invertebrates

Data not provided by the registrant

Long–term toxicity to aquatic invertebrates

Data not provided by the registrant

Toxicity to aquatic algae and cyanobacteria

Data not provided by the registrant

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Data not provided by the registrant

Sediment toxicity

Data not provided by the registrant

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Data not provided by the registrant

Toxicity to terrestrial arthropods

Data not provided by the registrant

Toxicity to terrestrial plants

Data not provided by the registrant

Toxicity to soil microorganisms

Data not provided by the registrant

Toxicity to birds

Data not provided by the registrant

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

Data not provided by the registrant

Toxicokinetics, metabolism, and distribution

Data not provided by the registrant

Acute toxicity

Data not provided by the registrant

Irritation / corrosion

Data not provided by the registrant

Sensitisation

Data not provided by the registrant

Repeated dose toxicity

Data not provided by the registrant

Genetic toxicity

Data not provided by the registrant

Carcinogenicity

Data not provided by the registrant

Toxicity to reproduction

Data not provided by the registrant

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant