Brief Profile

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
231-668-3
CAS no.:
7681-52-9
Index number:
017-011-00-1
Molecular formula:
ClNaO
SMILES:
[Na+].[O-]Cl
InChI:
InChI=1S/ClO.Na/c1-2;/q-1;+1
Type of substance:
Mono constituent substance
Origin:
Inorganic
Registered compositions:
38
Of which contain:
12 impurities relevant for classification
1 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP13) approved by the European Union, this substance causes severe skin burns and eye damage, is very toxic to aquatic life, is very toxic to aquatic life with long lasting effects and causes serious eye damage.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance may be corrosive to metals, causes skin irritation and may cause respiratory irritation.

Breakdown of all 2324 C&L notifications submitted to ECHA

Aquatic Acute 1 H400 Harmonised Classification
Skin Corr. 1B H314 Harmonised Classification
Eye Dam. 1 H318 Harmonised Classification
Met. Corr. 1 H290
Aquatic Chronic 1 H410 Harmonised Classification
STOT SE 3 H335
Aquatic Chronic 2 H411
Skin Irrit. 2 H315
Eye Irrit. 2 H319
Aquatic Chronic 3 H412
Acute Tox. 4 H302
Skin Corr. 1A H314
Ox. Sol. 2 H272
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 77 active registrations under REACH, 2 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Industrial accident prevention and reporting requirements have been established for this substance.
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
This substance is approved for use as a Biocidal Active Substance
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is approved for use as a biocide in the EEA and/or Switzerland, for: human hygiene, disinfection, veterinary hygiene, food and animals feeds, drinking water.

This substance is being reviewed for use as a biocide in the EEA and/or Switzerland, for: preservation for liquid systems, controlling slimes.

This substance is used in the following products: washing & cleaning products, textile treatment products and dyes, water treatment chemicals, perfumes and fragrances and cosmetics and personal care products.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance is used in the following activities or processes at workplace: closed batch processing in synthesis or formulation.

Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

This substance is used in the following products: washing & cleaning products.

This substance is used in the following areas: health services and formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: food products, chemicals, textile, leather or fur and wood and wood products.

This substance is used in the following activities or processes at workplace: treatment of articles by dipping and pouring, transfer of substance into small containers, laboratory work, roller or brushing applications, mixing in open batch processes and non-industrial spraying.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance is used in the following products: biocides (e.g. disinfectants, pest control products), pH regulators and water treatment products, paper chemicals and dyes, textile treatment products and dyes, washing & cleaning products and water treatment chemicals. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, transfer of substance into small containers, batch processing in synthesis or formulation with opportunity for exposure, mixing in open batch processes, closed, continuous processes with occasional controlled exposure, closed processes with no likelihood of exposure and production of mixtures or articles by tabletting, compression, extrusion or pelletisation.

Release to the environment of this substance can occur from industrial use: formulation of mixtures and manufacturing of the substance.

This substance is used in the following products: washing & cleaning products, water treatment chemicals, pH regulators and water treatment products, textile treatment products and dyes and paper chemicals and dyes. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: municipal supply (e.g. electricity, steam, gas, water) and sewage treatment. This substance is used for the manufacture of: chemicals, food products, textile, leather or fur and pulp, paper and paper products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, transfer of substance into small containers, mixing in open batch processes, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure and batch processing in synthesis or formulation with opportunity for exposure.

Release to the environment of this substance can occur from industrial use: as processing aid and as an intermediate step in further manufacturing of another substance (use of intermediates).

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, transfer of substance into small containers, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure and closed processes with no likelihood of exposure.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance and formulation of mixtures.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: avoid release to the environment; do not breathe the dust, fume, gas, mist, vapours or spray; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: Absorb spillage to prevent material damage. If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. If skin irritation occurs: Get medical advice/attention. Immediately call a poison center or doctor/physician. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.

Storage statements

Store this substance in a well-ventilated place and keeping container tightly closed.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • 3V Sigma S.p.A, Torquato Tasso 58 24121 Bergamo Italy
  • A.C.R.A.F. Spa, Via Amelia 70 00181 Roma Italy
  • ADAMA Agriculture BV, Arnhemseweg 87 Postbus 355 3830 AK Leusden Netherlands
  • ALTAIR CHIMICA SPA, VIA MOIE VECCHIE 13 56048 SALINE DI VOLTERRA (PI) Italy
  • ANWIL SA, Torunska 222 87-805 Wloclawek kuj-pom Poland
  • ARKEMA FRANCE, 420 rue d'Estienne d'Orves 92700 COLOMBES France
  • B-Lands Consulting (811314-0), World Trade Center 5 Place Robert Schuman - BP 1510 38025 Grenoble France France
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • Biomca Química, S.L., C/VÍA ESPALDÓN DÁRSENA PESQUERA, 3. 38120 SANTA CRUZ DE TENERIFE Spain
  • Bochemie a.s., Lidicka 326 735 81 Bohumin Czech Republic
  • Bondalti Cantábria S.A, Avenida Rey Alberto I de Bélgica s/n, 39300 Torrelavega Cantábria Spain
  • BONDALTI CHEMICALS, S.A., Quinta da Industria Beduido 3860-680 Estarreja Portugal
  • Borregaard AS, Hjalmar Wessels vei 6 1701 Sarpsborg Norway
  • BorsodChem, Bolyai ter 1 3700 Kazincbarcika Hungary
  • CABB GmbH, Ludwig-Hermann-Str. 100 86368 Gersthofen Germany
  • CABB Oy (OR of CABB AG), Kemirantie 1 P.O.Box 566 Kokkola Finland
  • CAFFARO BRESCIA S.r.l, viale Sondrio 2 20124 Milano Italy
  • CAFFARO INDUSTRIE S.P.A, P.le Marinotti, 1 33050 Torviscosa Udine Italy
  • Chimcomplex S.A. Borzesti, 3, Industriilor Street 601124 Onesti Bacau Romania
  • CHS Epi, a.s., Revoluční 1930/6 40032 Ústí nad Labem Czech Republic
  • Covestro Deutschland AG, Kaiser-Wilhelm-Allee 60 51373 Leverkusen Germany
  • COVESTRO, S.L., C/. Feixa LLarga, 7 08040 Barcelona Spain
  • DEKITRA S.A., Ctra. Miranda de Ebro a Puentelarrá km.5 Pol. Ind. Lantarón 01213 LANTARON Alava Spain
  • DniproAZOT Trade, Stochovska 50/821 16100 Praha Czech Republic
  • Donau Chemie Aktiengesellschaft, Am Heumarkt 10 1037 Vienna Vienna Austria
  • Ecolab Production Belgium B.V.B.A., Havenlaan 4 3980 Tessenderlo Belgium
  • ELECTROQUÍMICA DE HERNANI, S.A., EPELE 20120 HERNANI Spain
  • Electroquímica Onubense, S.L., Industrial Nuevo Puerto, 0 21810 Palos de la Frontera Huelva Spain
  • Ercros SA, Avenida Diagonal 593-595 08014 Barcelona Spain
  • Fater S.p.A, Via Mare Adriatico, 122 65010 Spoltore Italy
  • Fater SpA Joint Venture of Procter & Gamble / Angelini Group, Via Alessandro Volta, 10 65129 PESCARA PE Italy
  • Finchimica S.p.A., Via Lazio 13, 25025 Manerbio (BS) Italy
  • FORTISCHEM a.s., M.R.Stefanika 1 972 71 Novaky Slovakia
  • GAZECHIM, 2 boulevard Bertrand Duguesclin 34500 BEZIERS France
  • HALO INDUSTRY S.P.A, piazzale Franco Marinotti 1 33050 TORVISCOSA (UD) Italy
  • HydroChem Italia S.r.l., Via Mario Massari, 30/32 IT-28886 Pieve Vergonte VB Italy
  • INEOS Chlor Atlantik GmbH, Inhausersieler Str. 25 26388 Wilhelmshaven Niedersachsen Germany
  • INOVYN España S.L., Marie Curie 1-3-5 08760 MARTORELL Spain
  • INOVYN France S.A.S., Avenue de la République 39500 Tavaux France
  • INOVYN Manufacturing Belgium SA, Rue Solvay 39 5190 Jemeppe Sur Sambre Belgium
  • INOVYN Produzione Italia S.p.A, VIA PIAVE, 6 57013 ROSIGNANO SOLVAY LIVORNO Italy
  • INQUIDE, S.A., Passeig Sanllehy, 25 08213 Polinyà Barcelona Spain
  • interchim sa, 7th km Old National Road Thessaloniki - Kilkis 57008 Ionia Thessaloniki Greece
  • Intertek Deutschland GmbH 49, Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany
  • Kapachim S.A., El. Venizelou 128, N. Ionia 14231 Athens Attiki Greece
  • Kem One, IMMEUBLE LE QUADRILLE 19 RUE JACQUELINE AURIOL 69008 LYON France
  • Kemira Chemicals Oy, Harmajantie 3 P.O Box 7 FI-32741 SASTAMALA Finland
  • KISCHEMICALS LLC, Gyártelep 3792 Sajóbábony Hungary
  • Kuhlmann France, rue Georges Clemenceau 59120 Loos Hauts-de-France France
  • Micro-bio (Ireland) Ltd., Industrial Estate Fermoy North P61X977 fermoy Co. cork Ireland
  • MSSA, Pombliere 73600 Saint Marcel France
  • Nobian GmbH, Hauptstraße 47 49479 Ibbenbüren Germany
  • Nobian Industrial Chemicals B.V., Van Asch van Wijckstraat 53 3811 LP Amersfoort Netherlands
  • PCC Rokita SA, Sienkiewicza 4 56-120 Brzeg Dolny Poland
  • Pharmatek S.r.l., Viale Henry Dunant, 93 46043 Castiglione delle Stiviere (MN) Italy
  • QUÍMICA DEL CINCA, S.L., Avda. Diagonal 352 08013 Barcelona Barcelona Spain
  • REACH GLOBAL SERVICES S.A., Rond Point Schuman, 6 B-1040 Brussels Belgium
  • REACH MONITOR SLU , Carrer Orient 78-84 5è, 2a 08072 Sant Cugat del Vallès Spain
  • REACHLaw Ltd., Vänrikinkuja 3 JK 21 02600 Espoo Finland
  • S.E. de Carburos Metálicos, S.A., Av. de la Fama, 1 08940 Cornellà de Llobregat (Barcelona) Spain
  • SABIC Innovative Plastics BV, Plasticslaan 1 4612 PX Bergen op Zoom Netherlands Netherlands
  • Sadachit Prodcom SRL, 3, Nicolae Teclu 12c, 22Decembrie 1989 401115 Turda Cluj county Romania
  • SC Johnson Benelux , Groot Mijdrechtstraat 81 3641 RV Mijdrecht Netherlands
  • Siemens Healthcare Diagnostics Products GmbH, Emil-von-Behring-Str. 76 35041 Marburg Germany
  • SIPCAM OXON SPA, Via Sempione, 195 20016 Pero Milano Italy
  • SOCIETA' CHIMICA BUSSI S.P.A., Piazzale Elettrochimica 1 65022 Bussi sul Tirino Italy
  • Società Chimica Assemini S.R.L., Via del Brennero 48 56123 Pisa Italy
  • SPCH, route de Guillaucourt 80131 HARBONNIERES France
  • SPOLANA s.r.o., Ul. Práce 657 277 11 Neratovice Czech Republic
  • SUSTCHEM S.A., 144, 3rd Septemvriou 11251 Athens Attica Greece
  • TKI Hrastnik d.d., Za Savo 6 1430 Hrastnik Slovenia
  • Vencorex France_1, 196 Allée Alexandre Borodine 69800 Saint Priest France
  • Vinyl Vegyipari Gyártó és Forgalmazó Korlátolt Felelősségű Társaság, Illatos út 19-23. 1097 Budapest Hungary
  • Vynova Belgium NV, H.Hartlaan, 21 BE-3980 Tessenderlo Belgium
  • Vynova PPC SAS, 95 rue du Général de Gaulle BP 60090 68802 THANN CEDEX France
  • Westlake Vinnolit GmbH & Co. KG, Carl-Zeiss-Ring 25 85737 Ismaning Germany
  • Yordas GmbH, Äußere Nürnberger Straße 62 91301 Forchheim Germany
  • Arcerion GmbH, Gabrielenstr. 15 80636 München Germany
  • Brenntag Inorganic Chemicals (Thetford) Limited, Alpha House, Redvers Close Lawnswood Business Park LS16 6QY Leeds West Yorkshire United Kingdom
  • CBee (Europe) Limited, The Mille 1000 Great West Road TW8 9HH Brentford Middlesex United Kingdom
  • ELNOSA – ELECTROQUÍMICA DEL NOROESTE, SA, MARISMA DE LOURIZÁ S/N APT. 265 36153 PONTEVEDRA Spain
  • Hellenic Petroleum R.S.S.O.P.P. S.A., 8A Chimarras street 15125 Marousi Attica Greece
  • HyChem – Química Sustentável, S.A, RUA ENG. CLEMENT DUMOULIN 2625-106 POVOA DE SANTA IRIA Portugal
  • LAXMI ORGANIC INDUSTRIES (EUROPE) B.V., BURGEMEESTER FEITHPLEIN 11 2273 BZ VOORBURG Netherlands
  • Mexichem UK Limited, The Heath Business and Technical Park WA7 4QX Runcorn Cheshire United Kingdom
  • Nouryon Finland Oy, Nuottasaarentie 17 90400 Oulu Finland
  • NuFarm Limited, Wyke Lane BD12 9EJ Wyke West Yorkshire United Kingdom
  • Soltrade GmbH, Donau-City-Strasse 1 1220 Wien Austria Austria
  • UNILEVER KNORR S.A., 8 Himaras Street 15125 Athens Greece
  • ZACHEM S.A., Wojska Polskiego 65 85-825 Bydgoszcz Poland

Substance names and other identifiers

Active chlorine released from sodium hypochlorite
Biocidal active substances
Sodium hypochlorite
EC Inventory, REACH pre-registration, Other
Sodium hypochlorite
REACH pre-registration, Other, Statistics on Pesticides Regulation - Annex III Harmonized C&L
sodium hypochlorite, solution ... % Cl active
C&L Inventory
sodium hypochlorite, solution... % Cl active
CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
...% Cl aktyv. natrio hipochlorito tirpalas (lt)
C&L Inventory
Aktivchlor, freigesetzt aus Natriumhypochlorit (de)
Biocidal active substances
aktivni klor oslobođen iz natrijeva hipoklorita (hr)
Biocidal active substances
Aktivni klor, sproščen iz natrijevega hipoklorita (sl)
Biocidal active substances
aktivní chlor uvolněný z chlornanu sodného (cs)
Biocidal active substances
Aktivt chlor frigivet fra natriumhypochlorit (da)
Biocidal active substances
Aktivt klor frigjort fra natriumhypokloritt (no)
Biocidal active substances
Aktivt klor frisatt från natriumhypoklorit (sv)
Biocidal active substances
Aktywny chlor uwalniany z podchlorynu sodu (pl)
Biocidal active substances
Aktívny chlór uvoľnený z chlórnanu sodného (sk)
Biocidal active substances
chloran(I) sodu, roztwór zawierajacy ... % aktywnego Cl podchloryn sodu, roztwór zawierajacy ... % aktywnego Cl (pl)
C&L Inventory
Chlore actif libéré à partir d'hypochlorite de sodium (fr)
Biocidal active substances
chlornan sodný, roztok, obsah aktivního chloru …% (cs)
C&L Inventory
chlórnan sodný, roztok s ... % aktívneho chlóru (sk)
C&L Inventory
Clor activ eliberat din hipoclorit de sodiu (ro)
Biocidal active substances
Cloro activo liberado a partir de hipoclorito de sodio (es)
Biocidal active substances
Cloro ativo libertado por hipoclorito de sódio (pt)
Biocidal active substances
Cloro attivo rilasciato da ipoclorito di sodio (it)
Biocidal active substances
hipoclorit de sodium, solutie….%Cl activ (ro)
C&L Inventory
hipoclorito de sodio, solución ... % cloro activo hipoclorito de sodio, disolución ... % cloro activo (es)
C&L Inventory
hipoclorito de sódio, solução ... % Cl activo (pt)
C&L Inventory
hypochlorite de sodium, solution à …% de chlore actif (fr)
C&L Inventory
ipoclorito di sodio, soluzione ... % Cl attivo sodio ipoclorito, soluzione ... % Cl attivo (it)
C&L Inventory
Iš natrio hipochlorito išskirtas aktyvusis chloras (lt)
Biocidal active substances
Kloru attiv rilaxxat mill-ipoklorit tas-sodju (mt)
Biocidal active substances
Naatriumhüpoklorit, lahus …% aktiivset kloori (et)
C&L Inventory
naatriumhüpokloritist vabanenud aktiivkloor (et)
Biocidal active substances
natrijev hipoklorit, otopina ... % aktivnog Cl (hr)
C&L Inventory
natrijev hipoklorit...%, raztopina z aktivnim klorom (sl)
C&L Inventory
natriumhypochloriet, oplossing ... % Cl actief (nl)
C&L Inventory
Natriumhypochloritlösung ... % Cl aktiv (de)
C&L Inventory
natriumhypochloritopløsning ... % aktiv chlor (da)
C&L Inventory
Natriumhypokloriitista vapautunut aktiivinen kloori (fi)
Biocidal active substances
Natriumhypokloriitti, liuos, aktiivikloorin määrä ...% (fi)
C&L Inventory
natriumhypokloritlösning ... % aktivt klor (sv)
C&L Inventory
natriumhypoklorittløsning ... % aktiv klor (no)
C&L Inventory
No nātrija hipohlorīta izdalījies aktīvais hlors (lv)
Biocidal active substances
nátrium-hipoklorit oldat ...% aktív klór (hu)
C&L Inventory
Nátrium-hipokloritból felszabaduló aktív klór (hu)
Biocidal active substances
nātrija hipohlorīts, ...% aktīvā hlora šķīdums (lv)
C&L Inventory
Uit natriumhypochloriet vrijgekomen actief chloor (nl)
Biocidal active substances
Ενεργό χλώριο εκλυόμενο από υποχλωριώδες νάτριο (el)
Biocidal active substances
υποχλωριώδες νάτριο, διάλυμα ... % ενεργό χλώριο (el)
C&L Inventory
Активен хлор, освободен от натриев хипохлорит (bg)
Biocidal active substances
разтвор на натриев хипохлорит... % Сl активен (bg)
C&L Inventory
Active chlorine released from sodium hypochlorite
Biocidal active substances
Bleach
Registration dossier
hipoclorito de sodio
C&L Inventory
hypochlorite de sodium
Registration dossier
hypochlorous acid, sodium salt
Registration dossier
Hypochlorous acid, sodium salt (1:1)
C&L Inventory
Hypochlorous acid, sodium salt (NaOCl)
C&L Inventory
JAVEL or EAU DE JAVEL or BLEACH
Registration dossier
Natriumhypochlorid
C&L Inventory
Natriumhypochloritloesung ... % Cl
C&L Inventory
Neutral+Ion
C&L Inventory
Nátrium-hipoklorit
Registration dossier
Sodim hypochlorite
Registration dossier
sodium chlorite
C&L Inventory
sodium hypochloride
C&L Inventory
sodium hypochloride
Registration dossier
sodium hypochlorit
C&L Inventory
SODIUM HYPOCHLORITE
C&L Inventory, Registration dossier, Other
Sodium Hypochlorite
C&L Inventory, Registration dossier, Other
Sodium hypochlorite (SCI)
Registration dossier
sodium hypochlorite (solution (contains 75% effective chlorine ))
C&L Inventory
sodium hypochlorite aqueous solution
Registration dossier
Sodium hypochlorite solution
C&L Inventory
Sodium hypochlorite, bleach
Registration dossier
sodium hypochlorite, solution
C&L Inventory
sodium hypochlorite, solution ... % Cl active
C&L Inventory
sodium hypochlorite, solution ...% Cl active
C&L Inventory
sodium hypochlorite, solution ... % Cl active
C&L Inventory
sodium hypochlorite, solution 12-15% Cl active
C&L Inventory
sodium hypochlorite, solution 15 % Cl active
C&L Inventory
sodium hypochlorite, solution...% cl active
C&L Inventory
sodium;hypochlorite
Other
Antiformin
Registration dossier
Astonish Specialist Αντιμουχλικό
C&L Inventory
B-K Liquid
Registration dossier
Bleach
Registration dossier
bleach liquor
Registration dossier
Carrel-Dakin solution
Registration dossier
Chloros
Registration dossier
Clorox
Registration dossier
Dakin's solution
Registration dossier
Dakins Solution
Registration dossier
Deosan
Registration dossier
eau de javel
Registration dossier
Hipoclorito de sodio
C&L Inventory
Hyclorite
Registration dossier
Hypo
Registration dossier
Hypochlorous acid, sodium salt
Registration dossier
Hypochlorous acid, sodium salt (8CI, 9CI)
Registration dossier
Hypochlorous acid, sodium salt (CAS Registry 8CI, 9CI)
Registration dossier
Hypochlorous acid, sodium salt (CAS Registry 8Cl, 9Cl
Registration dossier
Hypochlorous acid, sodium salt (CAS Registry 8Cl, 9Cl)
Registration dossier
Hypoclorite
Registration dossier
Javel water
Registration dossier
Javel water, Household Bleach
Registration dossier
Javelle water
Registration dossier
Javex
Registration dossier
Jawel water
Registration dossier
Klorocin
Registration dossier
Milton
Registration dossier
Modified Dakin's solution
Registration dossier
Named reagents and solutions, Dakin's
Registration dossier
Natriumhypochlorit-Lösung (german)
Registration dossier
NATRONBLEICHLAUGE
Registration dossier
Natronbleichlauge (german)
Registration dossier
Neo-cleaner
Registration dossier
Neoseptal CL
Registration dossier
Neutralion
C&L Inventory
Parozone
Registration dossier
Podchloryn S
Registration dossier
podchloryn sodu
Registration dossier
Podchloryn sodu techniczny
Registration dossier
Purin B
Registration dossier
Sodium chloride oxide
Registration dossier
Sodium Hypochlorite
Registration dossier
Sodium hypochlorite (EINECS)
Registration dossier
Sodium hypochlorite (NaClO)
Registration dossier
Sodium hypochlorite (NaOCl)
Registration dossier
Sodium hypochlorite 10 %
Registration dossier
Sodium hypochlorite 15 %
Registration dossier
Sodium Hypochlorite 47-50 grade
Registration dossier
Sodium Hypochlorite 50° chlorometric
Registration dossier
Sodium hypochlorite, D Grade
Registration dossier
Sunnysol 150
Registration dossier
THYCAL
Registration dossier
XY 12
Registration dossier
017-011-00-1
Index number
C&L Inventory
102324-78-7
CAS number
Other
227453-69-2
CAS number
Other
56172-57-7
CAS number
Other
7681-52-9
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Statistics on Pesticides Regulation - Annex III Harmonized C&L, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
8007-59-8
CAS number
Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 1 study submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [1]
C Form
Other (100%) [1]
C Odour
Other (100%) [1]
C Substance type
Inorganic (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 1 study submitted
  • 1 study processed
R Melting / freezing point
-28.9 °C @ 101.3 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
-28.9 °C

Boiling point

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Density

Study results
  • 1 study submitted
  • 1 study processed
R Relative density
1.3 @ 21.2 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Vapour pressure

Study results
  • 3 studies submitted
  • 2 studies processed
R Vapour pressure
0 - 2 500 Pa @ 20 °C [2]

Type of Study provided
Studies with data
Key study 1 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
0 Pa @ 20 °C

Partition coefficient

Study results
  • 1 study submitted
  • 1 study processed
R Log Pow
-3.42 @ 20 °C and pH 12.5 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
-3.42 @ 20 °C

Water solubility

Study results
  • 2 studies submitted
  • 1 study processed
R Water solubility (mass/vol.)
1 000 g/L @ 25 °C and pH 12.5 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
999.999 g/L @ 25 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Surface tension at 20 °C
82.4 mN/m @ 316 mg/L

Flash point

Study results
  • 1 study submitted
  • 1 study processed
R Flash point
111 °C @ 101.3 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Non flammable (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers

No summary exists for this scientific endpoint

Dissociation constant

Study results
  • 3 studies submitted
  • 1 study processed
C Dissociating properties
Yes (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 3 studies submitted
  • 3 studies processed
R dynamic viscosity (in mPa s)
1.1 - 6.6 [6]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Dynamic viscosity at 20 °C
6.4 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 1 study submitted
  • 1 study processed
R Dissipation half life (DT50)
3.82 months [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Half life in air
3.833 months

Hydrolysis

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 1 study submitted
  • 1 study processed
R Dissipation Half-life (DT50)
12 - 60 min [3]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
R Summaries
  • 1 summary submitted
  • 1 summary processed
Koc at 20°C
0.001

Henrys law constant (H)

Study results
  • 1 study submitted
  • 1 study processed
R H - dimensionless
0.076 @ 20 °C and 100 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Henry's law constant
0.076 Pa.m³.mol-1 @ 20 °C

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 210 ng/L (1)
Intermittent releases (freshwater) 260 ng/L (1)
Marine water 42 ng/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 4.69 mg/L (1)
Sediment (freshwater) No exposure of sediment expected (1)
Sediment (marine water) No exposure of sediment expected (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil No exposure of soil expected (1)
Hazard for Predators
Secondary poisoning 11.1 mg/kg food (1)

Short–term toxicity to fish

Study results
  • 36 studies submitted
  • 1 study processed
P/RResults
LC50 (5 days) 50 µg/L [2]

Type of Study provided
Studies with data
Key study 1 1
Supporting study 5 28
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 35 studies submitted
  • 5 studies processed
P/RResults
EC50 (48 h) 26 - 141 µg/L [3]
LC50 (72 h) 90 - 180 µg/L [2]
LC50 (48 h) 29 - 260 µg/L [7]
LC50 (24 h) 70 - 55 000 µg/L [7]
NOEC (48 h) 25 - 50 µg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 3 27
Weight of evidence 2 1
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 6 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 5
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 14 studies submitted
  • 1 study processed
P/RResults
EC50 (72 h) 18.3 - 36.5 µg/L [2]
NOEC (72 h) 5.4 µg/L [1]
LOEC (72 h) 5.4 - 23.3 µg/L [2]
EC10 (72 h) 6.2 - 19.9 µg/L [2]
EC20 (72 h) 9 - 24.5 µg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 2 10
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
49.9 µg/L
EC10 or NOEC for freshwater algae
2.1 µg/L

Toxicity to aquatic plants other than algae

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
EC50 (4 days) 100 - 400 µg/L [1]
NOEC (4 days) 20 - 50 µg/L [5]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater plants
100 µg/L
EC10 or NOEC for freshwater plants
20 µg/L

Toxicity to microorganisms

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC50 (3 h) 3 - 563 mg/L [3]
NOEC (3 h) 41.1 - 300 mg/L [2]
EC10 (3 h) 46.9 - 342 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for microorganisms
77.1 mg/L
EC10 or NOEC for microorganisms
46.9 mg/L

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 4 studies submitted
  • 1 study processed
P/RResults
NOEC (70 days) 200 mg/L drinking water [1]
LOEC (70 days) 400 mg/L drinking water [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Long-term EC10 / LC10 / NOEC
200 mg/kg food

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 1.55 mg/m³ repeated dose toxicity
Acute /short term: (DNEL) 3.1 mg/m³ repeated dose toxicity
Local Effects
Long-term: (DNEL) 1.55 mg/m³ repeated dose toxicity
Acute /short term: (DNEL) 3.1 mg/m³ repeated dose toxicity
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: Low hazard (no threshold derived)
Local Effects
Long-term: - -
Acute /short term: Low hazard (no threshold derived)
EYE Exposure
Low hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 1.55 mg/m³ repeated dose toxicity
Acute /short term: (DNEL) 3.1 mg/m³ repeated dose toxicity
Local Effects
Long-term: (DNEL) 1.55 mg/m³ repeated dose toxicity
Acute /short term: (DNEL) 3.1 mg/m³ repeated dose toxicity
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: Low hazard (no threshold derived)
Local Effects
Long-term: - -
Acute /short term: Low hazard (no threshold derived)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 260 µg/kg bw/day repeated dose toxicity
Acute /short term: Low hazard (no threshold derived)
EYE Exposure
Low hazard (no threshold derived)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 2
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 6 studies submitted
  • 1 study processed
P/RResults
LD50 1 100 mg/kg bw (rat) [1]
LD0 626 mg/kg bw (rat) [1]
M/CInterpretations of results
Study cannot be used for classification [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study 5
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

inhalation
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
dermal
  • 2 studies submitted
  • 1 study processed
P/RResults
LD50 20 000 mg/kg bw (rabbit) [1]
LD0 14 420 mg/kg bw (rabbit) [1]
M/CInterpretations of results
Not classified [1]

dermal
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

other routes
Studies with data
Key study
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Irritation / corrosion

Study results
Study data: skin
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 5
Weight of evidence
Other
Data waiving
no waivers
Study data: eye
  • 15 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study
Supporting study 14
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
Adverse effect observed (corrosive)
Eye
Adverse effect observed (irritating)
Respiratory
Adverse effect observed (irritating)

Sensitisation

Study results
Study data: skin
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 3 1
Weight of evidence
Other
Data waiving
no waivers
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 15 studies submitted
  • 3 studies processed
P/RResults
NOAEL (rat): 16.7 - 57.2 mg/kg bw/day [4]
NOAEL (mouse): 34.4 mg/kg bw/day [1]
LOAEL (rat): 16.7 - 114.4 mg/kg bw/day [4]
LOAEL (mouse): 34.4 mg/kg bw/day [1]

Type of Study provided
Study data: oral
Studies with data
Key study 3
Supporting study 3
Weight of evidence
Other 8 1
Data waiving
no waivers
Study data: inhalation
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route - systemic effects:
Adverse effect observed NOAEL 50 mg/kg bw/day (subchronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 21 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 5
Supporting study 14 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: in vivo
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 5
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 11 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 5
Supporting study 3 3
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: developmental
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
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Neurotoxicity

Data not provided by the registrant

Immunotoxicity

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Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant