Brief Profile

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

No image available
EC / List no.:
231-957-4
CAS no.:
7782-49-2
Index number:
034-001-00-2
Molecular formula:
Se
SMILES:
[Se]
InChI:
Type of substance:
Mono constituent substance
Origin:
Element
Registered compositions:
40
Of which contain:
5 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance is toxic if swallowed, is toxic if inhaled, may cause damage to organs through prolonged or repeated exposure and may cause long lasting harmful effects to aquatic life.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance may cause cancer, may damage fertility or the unborn child, is harmful to aquatic life with long lasting effects, may cause harm to breast-fed children and may cause an allergic skin reaction.

Breakdown of all 853 C&L notifications submitted to ECHA

Acute Tox. 3 H301 Harmonised Classification
Acute Tox. 3 H331 Harmonised Classification
STOT RE 2 H373 Harmonised Classification
Aquatic Chronic 4 H413 Harmonised Classification
Aquatic Chronic 3 H412
Carc. 1A H350
Repr. 1A H360
Lact. H362
Skin Sens. 1B H317
Aquatic Acute 1 H400
STOT SE 1 H370
STOT RE 1 H372
Repr. 2 H361
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

  • C*
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Carcinogenic (2.82% of REACH registrations). Of the minority indicating the property of concern, most indicate that it may relate to an impurity or additive rather than the substance itself.
  • R*
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Toxic to Reproduction (1.41% of REACH registrations). Of the minority indicating the property of concern, most indicate that it may relate to an impurity or additive rather than the substance itself.
  • Ss*
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Skin sensitising (1.41% of REACH registrations). Of the minority indicating the property of concern, most indicate that it may relate to an impurity or additive rather than the substance itself.

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 22 active registrations under REACH, 2 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Industrial accident prevention and reporting requirements have been established for this substance.
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.

This substance is used in articles, in formulation or re-packing, at industrial sites and in manufacturing.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles.

Release to the environment of this substance can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal). Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance can be found in complex articles, with no release intended: machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines) and electrical batteries and accumulators. This substance can be found in products with material based on: metal (e.g. cutlery, pots, toys, jewellery).

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the types of manufacture using this substance.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

This substance is used in the following products: metals.

This substance is used in the following activities or processes at workplace: closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens), open transfer and processing with minerals/metals at elevated temperature, handling of solid inorganic substances (e.g. ores and raw metal oxides, packaging/mixing/blending and weighing of metal powders), production of metal powders (hot processes) and production of metal powders (wet processes).

Release to the environment of this substance can occur from industrial use: formulation in materials.

This substance is used in the following products: coating products, metals and polymers.

This substance is used for the manufacture of: chemicals and food products.

This substance is used in the following activities or processes at workplace: closed batch processing in synthesis or formulation, handling of solid inorganic substances (e.g. ores and raw metal oxides, packaging/mixing/blending and weighing of metal powders), batch processing in synthesis or formulation with opportunity for exposure, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, production of mixtures or articles by tabletting, compression, extrusion or pelletisation, laboratory work, the low energy manipulation of substances bound in materials or articles, open transfer and processing with minerals/metals at elevated temperature and hot work operations with metals (e.g. welding, soldering, gouging, brazing, flame cutting).

Release to the environment of this substance can occur from industrial use: as processing aid, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates) and industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal).

This substance is used in the following activities or processes at workplace: potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens), open transfer and processing with minerals/metals at elevated temperature, handling of solid inorganic substances (e.g. ores and raw metal oxides, packaging/mixing/blending and weighing of metal powders), production of metal powders (hot processes), production of metal powders (wet processes), closed batch processing in synthesis or formulation and closed, continuous processes with occasional controlled exposure.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: do not breathe the dust, fume, gas, mist, vapours or spray; avoid release to the environment; wash parts of the body (as specified by manufacturer/supplier)in contact with substance thoroughly after handling; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: Call a poison center or doctor/physician if you feel unwell. Get medical advice/attention if you feel unwell. If swallowed: immediately call a poison center or doctor/physician. Follow specific treatment (see label). Remove/take off immediately all contaminated clothing.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • 5N Plus Belgium SA, rue de la station, 67 1495 Tilly Région wallonne Belgium
  • 5N Plus Lübeck GmbH, Kaninchenborn 24-28 23560 Luebeck Germany
  • Arcerion GmbH, Gabrielenstr. 15 80636 Muenchen Germany
  • Aurubis AG, Hovestrasse 50 20539 Hamburg Hamburg Germany
  • BLUESTONE METALS & CHEMICALS EUROPE S.L., c/ Pascual y Genis 1 46002 Valencia Spain
  • Boliden Harjavalta Oy, Teollisuuskatu 1 29200 Harjavalta Finland
  • Boliden Mineral AB, Rönnskärsverken 93281 Skelleftehamn Sweden
  • CENTRUM METAL ODCZYNNIKI CHEMICZNE - MIDAS INVESTMENT SPÓŁKA Z OGRANICZONĄ ODPOWIEDZIALNOŚCIĄ SP.K., ul. Opackiego 46A/11 05-090 Falenty Warszawa Poland
  • Fortis Metals GmbH, Großer Burstah 36/38 20457 Hamburg Germany
  • Glencore International Import BV, Prinses Beatrixlaan 582 2595 BM Den Haag Netherlands
  • Glencore Nikkelverk AS, Vesterveien 31 4606 Kristiansand Norway
  • HALMA Handels GmbH, Reichstratsstrasse 11/3 1010 Wien Austria
  • KGHM Polska Miedz S.A., ul. M. Skłodowskiej-Curie 48 59-301 Lubin Poland
  • Norilsk Nickel Harjavalta Oy (POLAR), Teollisuuskatu 1 FI-29200 Harjavalta Finland
  • REACHLaw Ltd., Vänrikinkuja 3 JK 21 02600 Espoo Finland
  • RETORTE GmbH, Sulzbacher Straße 45 90552 Röthenbach a.d. Pegnitz Germany
  • TODINI AND CO. SPA, Corso Milano 46 B 20900 MONZA ITALIA Italy
  • TODINI BV, Kleine Pathoekeweg 82 B-8000 Brugge Belgium
  • TÜV SÜD Industrie Service GmbH, Westendstraße 199 80686 München Germany
  • Umicore NV/SA, Rue du Marais 31 1000 Brussels Belgium
  • Vital MATERIALS EUROPE BVBA, Pegasuslaan 5 1830 Diegem Belgium
  • Yordas GmbH, Äußere Nürnberger Str. 6 91301 Forchheim Germany
  • 5N Plus UK Ltd, 1-4 Nielson Road Finedon Road Industrial Estate NN8 4PE Wellingborough Northants United Kingdom

Substance names and other identifiers

C.I. 77805
Other
Colloidal selenium
Other
Elemental selenium
Other
Gray selenium
Other
Selen
Other
Selenate
Other
Selenium
EC Inventory, C&L Inventory, REACH pre-registration, Other, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Pressure Equipment Directive - Group 1 Fluids Hazardous Substances, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
Selenium
C&L Inventory, REACH pre-registration, Other, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Water for Human Consumption Directive - Quality Criteria, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Pressure Equipment Directive - Group 1 Fluids Hazardous Substances, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
Selenium alloy
Other
Selenium base
Other
Selenium dust
Other
Selenium homopolymer
Other
Selenium metallicum
Other
Selenium, colloidal
Other
Selenium, elemental
Other
Selenium, metallic
Other
Vandex
Other
Seleen (et)
C&L Inventory
Seleeni (fi)
C&L Inventory
selen (cs)
C&L Inventory
selen (da)
C&L Inventory
Selen (de)
C&L Inventory
selen (hr)
C&L Inventory
selen (no)
C&L Inventory
selen (pl)
C&L Inventory
selen (sl)
C&L Inventory
selen (sv)
C&L Inventory
selenas (lt)
C&L Inventory
selenio (es)
C&L Inventory
selenio (it)
C&L Inventory
seleniu (ro)
C&L Inventory
selenium (nl)
C&L Inventory
selén (sk)
C&L Inventory
selénio (pt)
C&L Inventory
selēns (lv)
C&L Inventory
szelén (hu)
C&L Inventory
sélénium (fr)
C&L Inventory
σελήνιο (el)
C&L Inventory
селен (bg)
C&L Inventory
Selenium
Other
hydrogen selenide
Registration dossier
Se
C&L Inventory
Selenide
C&L Inventory
SELENIUM
C&L Inventory, Registration dossier, Other
Selenium
C&L Inventory, Registration dossier, Other
selenium metal
Registration dossier
selenium-
C&L Inventory
Feuchtselen
Registration dossier
Selenium crude
Registration dossier
034-001-00-2
Index number
C&L Inventory
11125-23-8
CAS number
Other
11125-23-8
Deleted CAS number
Other
11133-88-3
CAS number
Other
11133-88-3
Deleted CAS number
Other
12640-29-8
CAS number
Other
12640-29-8
Deleted CAS number
Other
12640-30-1
CAS number
Other
12640-30-1
Deleted CAS number
Other
12641-96-2
CAS number
Other
12641-96-2
Deleted CAS number
Other
12733-65-2
CAS number
Other
12733-65-2
Deleted CAS number
Other
37256-19-2
CAS number
Other
37256-19-2
Deleted CAS number
Other
37258-85-8
CAS number
Other
37258-85-8
Deleted CAS number
Other
37276-15-6
CAS number
Other
37276-15-6
Deleted CAS number
Other
37368-02-8
CAS number
Other
37368-02-8
Deleted CAS number
Other
50954-17-1
CAS number
Other
50954-17-1
Deleted CAS number
Other
51882-60-1
CAS number
Other
51882-60-1
Deleted CAS number
Other
7782-49-2
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Water for Human Consumption Directive - Quality Criteria, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Pressure Equipment Directive - Group 1 Fluids Hazardous Substances, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
95788-45-7
CAS number
Other
95788-45-7
Deleted CAS number
Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 2 studies processed
C Physical state at 20°C and 1013 hPa
Solid (100%) [2]
C Form
Powder (100%) [2]
C Odour
Other (100%) [2]
C Substance type
Element (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Physical state at 20°C and 1013 hPa
Solid (100%)

Melting/freezing point

Study results
  • 2 studies submitted
  • 2 studies processed
R Melting / freezing point
220.8 °C @ 101.325 kPa [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Melting / freezing point at 101 325 Pa
220.8 °C

Boiling point

Study results
  • 2 studies submitted
  • 2 studies processed
R Boiling point
685 °C @ 101.325 kPa [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Boiling point at 101 325 Pa
685 °C

Density

Study results
  • 2 studies submitted
  • 2 studies processed
R Relative density
4.809 @ 25 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Relative density at 20°C
4.809

Vapour pressure

Study results
  • 2 studies submitted
  • 2 studies processed
R Vapour pressure
0.133 Pa @ 20 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Vapour pressure
0.133 Pa @ 20 °C

Partition coefficient

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Water solubility

Study results
  • 6 studies submitted
  • 4 studies processed
R Water solubility (mass/vol.)
1.011 - 21 µg/L @ 20.5 °C and pH 6 - 8 [14]

Type of Study provided
Studies with data
Key study 4
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Water solubility
3.774 µg/L @ 21.2 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flash point

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Auto flammability

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 2 studies submitted
  • 2 studies processed
C Interpretation of results
Non flammable (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Flammability
Non flammable (100%)

Explosiveness

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidising

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Viscosity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 212 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 6 72
Weight of evidence 44 90
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Bioaccumulation Factor (BCF) - L/kg ww
944 L/kg ww

Bioaccumulation: terrestrial

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Adsorption/desorption

Study results
  • 44 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 9
Weight of evidence 11 21
Other 3
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 2 summaries submitted
  • 2 summaries processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 2.67 µg/L (2)
Intermittent releases (freshwater) 5.5 µg/L (2)
Marine water 2 µg/L (2)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 1.5 mg/L (2)
Sediment (freshwater) 8.2 mg/kg sediment dw (2)
Sediment (marine water) 6.2 mg/kg sediment dw (2)
Hazard for Air
Air No hazard identified (2)
Hazard for Terrestrial Organism
Soil 44 - 100 µg/kg soil dw (2)
Hazard for Predators
Secondary poisoning 1 mg/kg food (2)

Short–term toxicity to fish

Study results
  • 28 studies submitted
  • 6 studies processed
P/RResults
LC50 (4 days) 26.2 - 100 000 µg/L [16]

Type of Study provided
Studies with data
Key study 2 4
Supporting study 22
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 58 studies submitted
  • 11 studies processed
P/RResults
NOEC (8.6 months) 10 µg/L [2]
NOEC (3 months) 21 - 47.2 µg/L [4]
NOEC (60 days) 330 µg/L [2]
NOEC (28 days) 1.57 - 10 000 µg/L [8]
LOEC (8.6 months) 30 µg/L [2]

Type of Study provided
Studies with data
Key study 3 10
Supporting study 5 40
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 58 studies submitted
  • 4 studies processed
P/RResults
EC50 (48 h) 160.3 µg/L [2]
LC50 (48 h) 550 µg/L [2]

Type of Study provided
Studies with data
Key study 2 2
Supporting study 48
Weight of evidence
Other 6
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 21 studies submitted
  • 16 studies processed
P/RResults
NOEC (32 days) 1.05 - 1.62 mg/L [4]
NOEC (30 days) 303 - 2 953 µg/L [4]
NOEC (28 days) 44 - 74 000 µg/L [10]
NOEC (24 days) 100 µg/L [2]
NOEC (21 days) 3.42 - 100 000 µg/L [10]

Type of Study provided
Studies with data
Key study 2 14
Supporting study 3 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 23 studies submitted
  • 15 studies processed
P/RResults
EC50 (4 days) 31.6 - 45 000 µg/L [10]
EC50 (72 h) 1.73 - 44 240 µg/L [6]
NOEC (10 days) 995 - 1 030 µg/L [4]
NOEC (4 days) 197 - 39 500 µg/L [8]
NOEC (72 h) 547 - 4 570 000 ng/L [4]

Type of Study provided
Studies with data
Key study 4 12
Supporting study 5
Weight of evidence
Other 2
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
EC50 for freshwater algae
1.73 - 245 µg/L
EC50 for marine water algae
45 mg/L
EC10 or NOEC for freshwater algae
547 - 197 000 ng/L
EC10 or NOEC for marine water algae
11 mg/L

Toxicity to aquatic plants other than algae

Study results
  • 6 studies submitted
  • 6 studies processed
P/RResults
EC50 (14 days) 1.7 - 11.5 mg/L [12]
NOEC (14 days) 80 - 2 400 µg/L [12]

Type of Study provided
Studies with data
Key study 6
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater plants
1.7 mg/L
EC10 or NOEC for freshwater plants
80 µg/L

Toxicity to microorganisms

Study results
  • 10 studies submitted
  • 1 study processed
P/RResults
EC50 (3 h) 3.2 g/L [1]
NOEC (3 h) 100 mg/L [1]
EC10 (3 h) 590 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 3
Weight of evidence 3
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 or NOEC for microorganisms
100 mg/L

Sediment toxicity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 11 studies submitted
  • 2 studies processed
P/RResults
NOEC (42 days) 2.12 - 5.44 mg/kg soil dw [4]
LOEC (42 days) 2.9 - 5.8 mg/kg soil dw [4]
EC10 (42 days) 2.57 mg/kg soil dw [1]
LC10 (42 days) 6.53 mg/kg soil dw [1]
EC50 (42 days) 1.7 - 7.07 mg/kg soil dw [5]

Type of Study provided
Studies with data
Key study 3 1
Supporting study 1 1
Weight of evidence
Other 1 3
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
R Summaries
  • 2 summaries submitted
  • 1 summary processed
Long-term EC10 / LC10 / NOEC
2.57 mg/kg soil dw

Toxicity to terrestrial arthropods

Study results
  • 9 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 6
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 30 studies submitted
  • 4 studies processed
P/RResults
NOEC (5.167 months) 1 - 2.5 mg/kg soil dw [3]
NOEC (55 days) 2 mg/kg soil dw [1]
NOEC (42 days) 1 - 4 mg/kg soil dw [4]
NOEC (33 days) 1 - 5 mg/kg soil dw [3]
NOEC (30 days) 2 mg/kg soil dw [1]

Type of Study provided
Studies with data
Key study 5 1
Supporting study 6 11
Weight of evidence
Other 6
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
R Summaries
  • 2 summaries submitted
  • 1 summary processed
Long-term EC10 / LC10 / NOEC
1 mg/kg soil dw

Toxicity to soil microorganisms

Study results
  • 6 studies submitted
  • 4 studies processed
P/RResults
NOEC (8.975 years) 4.2 - 5.9 mg/kg soil dw [3]
NOEC (28 days) 5.9 - 20 mg/kg soil dw [5]
NOEC (21 days) 5.9 mg/kg soil dw [2]

Type of Study provided
Studies with data
Key study 3 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 27 studies submitted
  • 8 studies processed
P/RResults
NOEC (1.458 years) 2 - 8 mg/kg diet [4]
NOEC (6.533 months) 3 mg/kg diet [1]
NOEC (57 days) 10 mg/kg diet [4]
NOEC (46 days) 4 - 16 mg/kg diet [2]
NOEC (21 days) 1 mg/kg diet [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 7 6
Weight of evidence 7
Other 6
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Long-term EC10 / LC10 / NOEC
1 mg/kg food

Toxicity to mammals

Study results
  • 13 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 9 4
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 50 µg/m³ -
Acute /short term: No hazard identified
Local Effects
Long-term: Hazard unknown (no further information necessary)
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 7 mg/kg bw/day -
Acute /short term: Hazard unknown (no further information necessary)
Local Effects
Long-term: Hazard unknown (no further information necessary)
Acute /short term: No hazard identified
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 15 µg/m³ -
Acute /short term: No hazard identified
Local Effects
Long-term: Hazard unknown (no further information necessary)
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 4.3 mg/kg bw/day -
Acute /short term: Hazard unknown (no further information necessary)
Local Effects
Long-term: Hazard unknown (no further information necessary)
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 4.3 µg/kg bw/day -
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 42 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence 42
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 9 studies submitted
  • 8 studies processed
P/RResults
LD50 7 - 500 mg/kg bw (rat) [5]
LD0 5 000 mg/kg bw (rat) [4]
LD50 23.3 mg/kg bw (mouse) [1]
M/CInterpretations of results
Category 2 based on GHS criteria [1]

Type of Study provided
oral
Studies with data
Key study 2
Supporting study 1
Weight of evidence 6
Other
Data waiving
no waivers
inhalation
  • 4 studies submitted
  • 4 studies processed
P/RResults
LC50 (4 h) 52 - 5 000 mg/m³ air (rat) [2]
LC0 (4 h) 5.67 mg/L air (rat) [2]
M/CInterpretations of results
Category 2 based on GHS criteria [1]

inhalation
Studies with data
Key study 1
Supporting study
Weight of evidence 3
Other
Data waiving
no waivers
dermal
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oral route:
Adverse effect observed LD50 7 mg/kg bw
Inhalation route:
Adverse effect observed LC50 52 µg/m³

Irritation / corrosion

Study results
Study data: skin
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 5 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 2 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No adverse effect observed (not irritating)

Sensitisation

Study results
Study data: skin
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1 3
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 18 studies submitted
  • 6 studies processed
P/RResults
NOAEL (rat): 0.4 mg/kg bw/day [3]
NOAEL (mouse): 0.8 - 0.9 mg/kg bw/day [3]

Type of Study provided
Study data: oral
Studies with data
Key study 2
Supporting study 5 4
Weight of evidence 2 2
Other 3
Data waiving
no waivers
Study data: inhalation
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Study data: dermal
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Oral route - systemic effects:
Adverse effect observed NOAEL 400 µg/kg bw/day (subchronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 20 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 1 2
Supporting study 1
Weight of evidence 4 1
Other 11
Data waiving
no waivers
Study data: in vivo
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 1 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 21 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 1 19
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 24 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study
Supporting study 1 8
Weight of evidence 3 4
Other 6
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Study data: developmental
  • 11 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2
Supporting study 1 2
Weight of evidence
Other 4
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Study data: other studies
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant