Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
236-675-5
CAS no.:
13463-67-7
Index number:
Molecular formula:
SMILES:
InChI:
Type of substance:
Mono constituent substance
Origin:
Inorganic
Registered compositions:
200
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Warning! According to the harmonised classification and labelling (ATP14) approved by the European Union, this substance is suspected of causing cancer.

According to the majority of notifications provided by companies to ECHA in CLP notifications no hazards have been classified.

Breakdown of all 16873 C&L notifications submitted to ECHA

Not Classified
Carc. 2 H351 Harmonised Classification
Acute Tox. 4 H332
STOT SE 3 H335
STOT RE 1 H372
Eye Irrit. 2 H319
Aquatic Chronic 4 H413
Carc. 1B H350
Acute Tox. 4 H302
STOT SE 2 H371
Skin Irrit. 2 H315
Acute Tox. 4 H312
Muta. 2 H341
STOT RE 2 H373
Eye Irrit. 2 H320
https://chesar.echa.europa.eu/diss-blank-theme/images/cnl/graph/more.png 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://chesar.echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://chesar.echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://chesar.echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

  • C
Suspected to be Carcinogenic (Harmonised C&L).

Nanomaterial form

Substance is known to be on the EEA market in nanomaterial form, as indicated in the REACH registered substance factsheet(s), and as listed in the EUON Nanomaterials in the EU market list.

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 296 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:
Nanomaterials in the EU Market

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 000 per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles, high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding), production of mixtures or articles by tabletting, compression, extrusion or pelletisation, open transfer and processing with minerals/metals at elevated temperature, hot work operations with metals (e.g. welding, soldering, gouging, brazing, flame cutting) and potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens).

Release to the environment of this substance can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal). Other release to the environment of this substance is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints).

This substance can be found in products with material based on: stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material), plastic (e.g. food packaging and storage, toys, mobile phones) and rubber (e.g. tyres, shoes, toys).

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following areas: building & construction work. This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following activities or processes at workplace: transfer of chemicals, handling of solid inorganic substances (e.g. ores and raw metal oxides, packaging/mixing/blending and weighing of metal powders), mixing in open batch processes and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: formulation of mixtures and formulation in materials.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following areas: building & construction work. This substance is used for the manufacture of: machinery and vehicles, chemicals and furniture.

This substance is used in the following activities or processes at workplace: transfer of chemicals.

Release to the environment of this substance can occur from industrial use: in the production of articles, in processing aids at industrial sites, as processing aid and as an intermediate step in further manufacturing of another substance (use of intermediates).

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: do not handle until all safety precautions have been read and understood; obtain special instructions before use; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If exposed or concerned: get medical advice/attention.

Storage statements

Store this substance locked up.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • 3M Belgium BVBA/SPRL, Hermeslaan 7 1831 Diegem Belgium
  • 3M France SAS, 1 Parvis de l'Innovation CS 20203 95006 Cergy-Pontoise Cedex France
  • A V Pound & Co. Ltd, Goolds Hill House Old Cork Road Ireland Mallow Co. Cork Ireland
  • AAKO BV, Arnhemseweg 87 3832 GK Leusden Netherlands
  • AKZO Nobel Car Refinishes B.V., Rijksstraatweg 31 2170 BA Sassenheim Netherlands
  • ALBEMARLE CATALYSTS COMPANY B.V., Nieuwendammerkade 1-3 PO Box 37650 1030 BE Amsterdam Netherlands
  • ALFARBEN, S.A., Partida Torreta s/n 12110 Alcora Castellón Spain
  • Amik Italia, VIA MECENATE 84B 20138 MILANO Italy Italy
  • Anthesis (Ireland) Limited 25, The Black Church St. Mary's Place D07 P4AX Dublin Ireland
  • B-Lands Consulting (811252-1), World Trade Center 5 Place Robert Schuman - BP 1510 38025 38025 France France
  • BASF Catalysts Germany GmbH, Seligmannallee 1 30173  Hannover Germany
  • BASF Coatings GmbH, Glasuritstrasse 1 Postfach 6123 48136 Münster Nordrhein-Westfalen Germany
  • BASF Colors & Effects GmbH, An der Rheinschanze 1 67059 Ludwigshafen Germany
  • BASF Colors & Effects Netherlands B.V., Sortieweg 39 6219NT Maastricht Netherlands
  • BASF Espanola S.L., Calle Can Ràbia, n. 3-5 8017 Barcelona Spain
  • BASF France S.A.S., 49, Avenue Georges Pompidou 92593 Levallois-Perret Cedex France
  • BASF Nederland B.V., Groningensingel 1 Postbus 1019 6801 MC Arnhem Netherlands
  • BASF Pigment GmbH, Carl-Bosch Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • BASF Polska Sp.z o.o., Aleje Jerozolimskie 154 02-326 Warszawa Poland
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • Beautyge, S.L., C/ Tirso de Molina, 40 08490 Cornella de Llobregat Spain
  • Beauté Prestige International, 56 A Rue du Faubourg Saint-Honoré 75008 Paris France
  • BERCEO CHEMICALS SL, Avenida del Ebro 167 ES26150 Arrubal La Rioja Spain
  • Blaskem Srl, Via Camillo Hajech 34 20129 Milano Italy
  • BorsodChem Zrt. - OR, Bolyai ter 1. H-3700 Kazincbarcika Hungary
  • C.S.B. GmbH, Düsseldorfer Str. 113 47809 Krefeld Germany
  • Caplinq Europe B.V., De Trompet 1126 1967 DA Heemskerk - Netherlands
  • Caplinq Europe BV, De Trompet 1126 1967DA Heemskerk Netherlands
  • CATHAY INDUSTRIES EUROPE n.v., Industriepark II Pamelstraat-Oost 442 B-9400 Ninove Belgium
  • Celanese Europe BV, The New Atrium Strawinskylaan 3105 1077 ZX Amsterdam Netherlands
  • cfm minerales, Camino de palos s/n. aptdo.345 12200 Onda Spain
  • Charles River Laboratories Den Bosch B.V. OR19, Hambakenwetering 7 5231 DD 's-Hertogenbosch Netherlands
  • ChemADVISOR Europe sprl, Rue Joseph Stevens 7 Office 1409B 1000 Brussels Belgium Belgium
  • Chemical Inspection & Regulation Service Limited, Unit 1 Ardee Business Park, Hale Street Co. Louth Ardee Ireland
  • Chemical Inspection & Regulation Service Limited, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre HW77 D02 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77, Dublin, Ireland D02 Dublin Ireland
  • Chemical Inspection & Regulation Service Limited, Room 002, Regus Harcourt Centre D02 HW77, Dublin, Ireland D02 Dublin Ireland
  • Chemical Inspection & Regulation Service Limited, Room 002, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland
  • Chemical Inspection & Regulation Service Limited, Room 002, Regus Harcourt Centre HW77 D02 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Unit 1 Ardee Business Park, Hale Street Co. Louth Ardee Ireland
  • Chemical Inspection & Regulation Service Limited, Room 002, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED (OR for Fujian Kuncai Material Technology Co., Ltd. ), Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED(Shandong Jinhai Titanium Resources Technology Co.,Ltd.), Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Chemical Technologies, SIA, Dzirnavu 92-3 LV-1050 Riga Latvia
  • Chemisphere Limited, Sutton House, Capenhurst Technology Park CH1 6EH Chester United Kingdom
  • Chemotex GmbH, Luftschiffring 8 68782 Brühl Germany
  • Chemours Netherlands B.V., Baanhoekweg 22 3313 LA Dordrecht Netherlands
  • Chemours Netherlands B.V._1, Baanhoekweg 22 3313 LA Dordrecht Netherlands
  • Chemours Netherlands B.V._2, Baanhoekweg 22 3313 LA Dordrecht Netherlands
  • Chemours Netherlands B.V._3, Baanhoekweg 22 3313 LA Dordrecht Netherlands
  • Chemservice S.A. (G7H4), 13, Fausermillen 6689 Mertert Luxembourg
  • Chemservice S.A. (H5P7), 13, Fausermillen 6689 Mertert Luxembourg
  • Cinkarna Celje, Kidričeva 26 3000 Celje Slovenia
  • Clariant Produkte (Deutschland) GmbH, Am Unisys-Park 1 65843 Sulzbach am Taunus Germany
  • Colorex S.r.l., via Procche 23 36030 Zugliano Italy
  • COSMETIQUE ACTIVE INTERNATIONAL, 28 rue du Président Wilson 03200 VICHY France
  • Coty Services and Logistics GmbH, Berliner Allee 65 64295 Darmstadt Germany
  • Coty Spain, S.L.U., Calla de la Marina 16-18, piso 16 Torre Mapfre 08005 Barcelona Spain
  • COVANCE CLINICAL DEVELOPMENT SA 052, Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 - 5 Planta 28050 Madrid Spain
  • COVANCE CLINICAL DEVELOPMENT SA 053, Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 - 5 Planta 28050 Madrid Spain
  • Covance Clinical Development SA 155, Parque Empresarial Las Tablas, Edifico 1 Calle Federico Mompou, 5 - 5 Planta 28050 Madrid Spain
  • COVANCE CLINICAL DEVELOPMENT SA 156, Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain
  • CPH Chemicals BV, Amsterdamseweg 204A 1182HL Amstelveen Netherlands
  • CRCP GmbH, Am Roemerhof 51 60486 Frankfurt am Main Germany
  • Cristal France SAS, 95 Rue du Général De Gaulle, B.P. 10059, F-68801, THANN CEDEX France
  • Croda Iberica SA, Mevisa Site Carretera C-35 Km 72 (Hostalric-Blanes) 08495 Fogars de la Selva Barcelona Spain
  • CSI-OR008, Pentlands Science Park Penicuik EH26 0PZ Edinburgh United Kingdom
  • Cytec Engineered Materials Ltd., Abenbury Way Wrexham Industrial Estate LL13 9UZ Wrexham United Kingdom
  • DELNEW srl, Via XX settembre 2/19 16121 Genova Italy
  • Dow Silicones Belgium SPRL, Rue Jules Bordet Zone industrielle C 7180 Seneffe Belgium
  • Dow Silicones Belgium SPRL OR-1, PSRC - rue Jules Bordet Parc industriel C 7180 Seneffe Belgium
  • DSM Engineering Materials B.V., Urmonderbaan 22 6167RD Geleen Netherlands
  • Du Pont de Nemours (Deutschland) GmbH, Hugenottenallee 173-175 D-63263 Neu-Isenburg Hesse Germany
  • DuPont de Nemours (Luxembourg) S.a.r.l., Rue General Patton 2984 Contern Luxembourg
  • Dynic UK Ltd, Unit 7 TRIDENT BUSINESS PARK GLASS AVENUE CF24 5EP Cardiff S.Glamorgan United Kingdom
  • Eckart GmbH, Guentersthal 4 D-91235 Hartenstein Bavaria Germany
  • Eckart Pigments KY, Titaanitie FIN-28840 Pori Finland
  • Edding International GmbH, Bookkoppel 7 22926 Ahrensburg Germany
  • EKOGRANULAT CARLO BURCHERT - EHM, Bellottiego 1 lok. 24 01-022 Warszawa Mazowieckie Poland
  • EMSA TECNOLOGIA QUIMICA S.A., C/ Mestre Nicolau, 19 8º 08021 Barcelona Catalunya Spain
  • Estee Lauder N.V., Nijverheidsstraat 15 2260 Oevel Belgium
  • Euro-Trade Spolka z ograniczona odpowiedzialnoscia Spolka Komandytowa, Łokietka 155 31-263 Kraków Poland
  • EVOCHEM Advanced Materials GmbH, Heinrich-Krumm-Strasse 20 63073 Offenbach am Main Germany
  • Evonik Operations GmbH, Rellinghauser Straße 1-11 45128 Essen Germany
  • Evonik Operations GmbH - Si 03, Rellinghauser Straße 1 - 11 45128 Essen Germany
  • Evonik Resource Efficiency GmbH, Rellinghauser Strasse 1-11 45128 Essen Germany
  • ExponentOR28, The Lenz Hornbeam Business Park HG28RE Harrogate Yorkshire United Kingdom
  • Faber-Castell AG, Nürnberger Str. 2 90546 Stein Germany
  • Ferro France S.A.R.L., 43 rue Jeanne d'Arc 52115 Saint-Dizier Cedex France
  • Ferro GmbH, Gutleutstr.215 60327 Frankfurt am Main Germany
  • Ferro Performance Pigments France, 92 Rue de la Lys BP 122 59433 Halluin Cedex France
  • FERRO SPECIALTY MATERIALS SPAIN, S.L.U., CTRA VALENCIA-BARCELONA, KM. 61,5 12550 ALMAZORA CASTELLÓN Spain
  • Fintex Chemie s.r.o., Národní 365/43 110 00 Praha 1 - Staré město Czech Republic
  • Fosbel GmbH, Karstrasse 116 41068 Mönchengladbach Germany
  • Fourpole Europe GmbH, Graf-Adolf-Platz 15 40213 Düsseldorf Germany
  • Genencor International B.V. - OR-US, Archimedesweg 30 2333 CN Leiden Netherlands
  • Global Product Compliance (Europe) AB, IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden
  • GOJO Industries – Europe Ltd., Units 5 & 6 Stratus Park Brinklow MK10 0DE Milton Keynes Buckinghamshire United Kingdom
  • Greiner Extrusion GmbH, Friedrich-Schiedel-Strasse 1 4542 Nussbach Austria
  • Grupa Azoty Zaklady Chemiczne "POLICE" Spolka Akcyjna, Kuznicka 1 72-010 Police Poland
  • GUZMAN GLOBAL S.L., Traginers, 9 46014 Valencia Valencia Spain
  • H.C. Starck Tungsten GmbH, Landsberger Str. 98 80339 München Germany
  • Helm AG, Nordkanalstraße 28 20097 Hamburg Germany
  • HELVET, s.r.o., Mládežnická 326 017 01 Považská Bystrica Slovakia
  • Henkel Global Supply Chain B.V., Gustav Mahlerlaan 2970 1081 LA Amsterdam Netherlands
  • HP Indigo B.V., Krijgsman 75 1186 DR Amstelveen The Netherlands Netherlands
  • IMCD Deutschland GmbH, Konrad-Adenauer-Ufer 50668 Köln Germany
  • Imerys Aluminates SA, 43 quai de Grenelle 75015 Paris France
  • International Speciality Chemicals Limited, 152-160 City Road EC1V 2NX London United Kingdom
  • Intertek Deutschland GmbH 1, Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany
  • Intertek Deutschland GmbH TOEV, Stangenstr.1 70771 Leinfelden-Echterdingen Germany
  • Iris Green s.r.l., V. Frediani,34 59100 PRATO ITALY Italy
  • ITACA, S.A., Partida Rambleta s/n 12191 Pobla Tornesa Castellón Spain
  • ITW Performance Polymers, A Division of ITW Ireland, Bay 150 Shannon Industrial Estate V14 DF82 Shannon Co. Clare Ireland
  • Johnson Matthey Catalysts (Germany) GmbH, Bahnhofstrasse 43 D-96257 Redwitz Germany
  • Johnson Matthey PLC, 5th Floor, 25 Farringdon Street EC4A 4AB London United Kingdom
  • K CHIMICA, Via Taglio Sinistro 63A 30035 Mirano Veneto Italy
  • KADION Especialidades Químicas, S.L., Can Rabia 15 Local 2 08017 Barcelona Barcelona Spain
  • Kao Chemicals GmbH, Kupferstrasse 1 46446 Emmerich Northrhine-Westfalia Germany
  • KIST Europe Forschungsgesellschaft mbH, Universitaet des Saarlandes Campus E 71 D-66123 Saarbrueken Germany
  • Knoell NL_OR_058, Agro Business Park 75 6708 PV Wageningen Netherlands
  • Kobelco Welding of Europe B.V., Eisterweg 8 6422 PN Heerlen Netherlands
  • Kobo Products SAS, 135 Rue Buissonnière Quartier Bouysset 31670 Labège France
  • Koninklijke Talens B.V. , Sophialaan 46 7311PD Apeldoorn Netherlands
  • Koopman International B.V., Distelweg 88 1031 HH Amsterdam Netherlands
  • KRONOS EUROPE S.A./N.V., Langerbruggekaai 10 9000 Gent Belgium
  • KRONOS INTERNATIONAL, Inc. (OR for Kronos Canada, Inc.), Peschstrasse 5 51373 Leverkusen Germany
  • KRONOS INTERNTIONAL, Inc. (OR for Louisiana Pigment Company, L.P.), Peschstrasse 5 51373 Leverkusen Germany
  • KRONOS TITAN AS, Titangaten 1 1630 Gamle Fredrikstad Norway
  • KRONOS TITAN GmbH, Peschstrasse 5 51373 Leverkusen Germany
  • KTR Europe GmbH, Mergenthalerallee 77 65760 Eschborn Germany
  • KUM YANG Europe GmbH, Mergenthalerallee 79-81 65760 Eschborn Germany
  • L'Aprochimide srl, Viale della Repubblica, 74 20835 Muggio' MI Italy
  • L'OREAL, 14 rue Royale 75008 Paris France
  • L'OREAL PRODUITS DE LUXE INTERNATIONAL, 106 rue Danton 92300 LEVALLOIS PERRET France
  • L'OREAL SAIPO INDUSTRIALE S.p.A., Strada della Cebrosa 52/56 10036 Settimo Torinese - TURIN Italy
  • Lehmann & Voss & Co. KG, Alsterufer 19 20354 Hamburg Hamburg Germany
  • LINCOLN ELECTRIC ITALIA S.r.l., Via Fratelli Canepa, 8 16010 Serra Riccò GE Italy
  • Lincoln Smitweld bv, Nieuwe Dukenburgseweg 20 6534 AD Nijmegen Netherlands Netherlands
  • LORD Germany Feinchemie GmbH, Gebäude 3666 06237 Leuna Sachsen Anhalt Germany
  • Lubrizol Advanced Materials Europe B.V.B.A, Nijverheidsstraat 30 2260 Westerlo-Oevel Belgium
  • Lubrizol Europe Coordination Center BVBA 02 , Chaussee De Wavre 1945 Brussels Belgium
  • Lubrizol Limited, The Knowle, Nether Lane Hazelwwod DE56 4AN Derby Derbyshire United Kingdom
  • MACRI CHEMICALS SRL, VIA E. CORNALIA 19 20124 MILANO Italy
  • MARIO PILATO BLAT, S.A., Paseo Alameda, 17 46010 Valencia Valencia Spain
  • Mascoat Products Ltd, Van Hilststraat 4 5145RL Waalwijk Netherlands
  • Merck KGaA, Frankfurter Strasse 250 64293 Darmstadt Germany
  • Merck KGaA OR 11, Frankfurter Str 64293 Darmstadt Germany
  • Merck Performance Materials Germany GmbH, Frankfurter Str. 250 64293 Darmstadt Germany
  • Michalczyk i Prokop Sp. z o.o., Skrzywana 9 93-588 Łódź Poland Poland
  • Milliken Europe B.V., Ham 18-24 9000 Gent Belgium
  • Miyoshi Europe SAS, 5 rue Paul Rieupeyroux 69800 Saint-Priest France
  • Momentive Performance Materials GmbH, Chempark Building V7 51368 Leverkusen NRW Germany
  • MÄC GEIZ Handelsgesellschaft mbH, Zörbiger Straße 6b 06188 Landsberg Germany
  • Nor-Cote International Ltd, Unit 8, Warrior Park, Eagle Close, Chandlers Ford Industrial Estate, SO53 4NF Eastleigh Hampshire United Kingdom
  • Novozymes A/S, Krogshoejvej 36 2880 Bagsvaerd Denmark
  • NYX PROFESSIONAL MAKEUP SPRL/BVBA, Avenue Charles-Quint 584 1082 Berchem-Sainte-Agathe Belgium
  • Oerlikon Metco Europe GmbH, Spreestrasse 2 65451 Kelsterbach Hessen Germany
  • Oerlikon Metco WOKA GmbH, Im Vorwerk 25 36456 Barchfeld-Immelborn Germany
  • Only representative (No publishable name), null
  • OSTCHEM Germany GmbH, Erdmannstr. 10 22765 Hamburg Germany
  • OWIM GmbH & Co. KG, Stiftsbergstr. 1 74172 Neckarsulm Germany
  • Pangang Europe GmbH, Graf-Adolf-Platz 15 40213 Düsseldorf Germany
  • Pelikan Vertriebsgesellschaft mbH & Co. KG, Werftstraße 9 30163 Hannover Germany
  • PPG Europe B.V. - OR1, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • PPG Europe B.V. - OR12, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • PPG Europe B.V. - OR3, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • PPG Europe B.V. in its legal capacity as Only Representative of PRC DeSoto International Inc. - OR5, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • PPG Industries Italia Srl Società soggetta a direzione e coordinamento da parte di PPG Industries Inc., Via Serra, 1 15028 Quattordio Italy
  • Precheza a.s. Přerov, Nábřeží Dr. E. Beneše 24 751 62 Přerov Czech Republic
  • Quaan GmbH, Harburger Schlossstrasse Channel 3 21079 Hamburg Germany
  • QUIMIALMEL ITALIA,S.P.A., VIA GHIAROLA VECCHIA,101 41042 FIORANO MODENESE MODENA Italy
  • QUIMIALMEL S.A., CL SAN ROQUE 15 12004 CASTELLON CASTELLON Spain
  • Ramboll Deutschland GmbH, Werinherstraße 79 Gebäude 32a 81541 München Bayern Germany
  • Reach Only Representative (Ireland) Ltd (guangx), VPR House Main Street F12 FC64 Swinford County Mayo Ireland
  • REACH24H CONSULTING GROUP, Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
  • REACHLaw Ltd, Vänrikinkuja 3 JK 21 02600 Espoo Finland
  • REACHLaw Ltd., Vänrikinkuja 3 JK 21 02600 Espoo Finland
  • Red Orchid Consulting Oy Ltd, Viherkallionkuja 3 I 59 02710 Espoo, Finland. 02710 Espoo Espoo Finland
  • REGARTIS s.r.o., Rubeška 393/7 19000 Prague Czech Republic
  • SABIC Innovative Plastics BV, Plasticslaan 1 4612 PX Bergen op Zoom Netherlands Netherlands
  • Saint-Gobain Coating Solutions, 50 RUE DU MOURELET B.P. 90966 84093 Avignon France
  • SCAS Europe S.A./N.V., Leonardo Da Vincilaan 19 B-1831 Diegem Belgium
  • SCHOTT AG, Hattenbergstr.10 55122 Mainz Germany
  • SEAVIEW PROGRESS, Zi du Capitou - 85 rue Louis Lépine 83600 Fréjus France
  • SEPR, BP 60025 Route de Lyon 84131 le pontet cedex France
  • Shepherd Europe SARL FO, 275, rue de Lorraine 88500 Juvaincourt France
  • Shiseido Group UK Limited, 10th Floor, The Adelphi 1-11 John Adam St WC2N 6HT London United Kingdom
  • SHOWA DENKO EUROPE GmbH, KONRAD-ZUSE-PLATZ 3 81829 München Germany
  • SHOWA DENKO EUROPE GmbH (STiC), Konrad-Zuse-Platz 3 81829 Munich Germany
  • SHPP B.V., Plasticslaan 1 4612PX Bergen op Zoom Netherlands
  • SINTERAMA S.P.A., via gramsci 5 13876 sandigliano Italy
  • SOCIETE BIC, 14 RUE JEANNE D'ASNIERES 92611 CLICHY France
  • Solvay Specialty Polymers Italy S.p.A., Viale Lombardia 20 20021 BOLLATE Italy
  • SOPROCOS, ZI Le Moulin de tous vents GAUCHY - BP294 02106 SAINT QUENTIN Cedex France
  • StonCor Europe, Rue du Travail, 9 1400 Nivelles Belgium
  • Sudarshan Europe B.V., Kingsfordweg 151 1043 GR Amsterdam Noord-Holland Netherlands
  • Sun Chemical A/S 7, Københavnsvej 112 4600 Køge Denmark
  • Sun Chemical B.V., Leeuwenveldseweg 3-t 1382 LV Weesp Netherlands
  • Syngenta Hellas AEBE, Anthousas Avenue 153 49 Anthousa-Attiki Greece
  • TAJER Tadeusz Ściwiarski, Mszczonowska 59e 05-830 Nadarzyn Masovian Voivodship Poland
  • TANIOBIS Smelting GmbH & Co. KG, Im Schleeke 78 -91 38642 Goslar Germany
  • Teknor Apex BV, Mijnweg 1 Mijnweg 1, (P.O.Box 601, 6160 AP) 6167AC Geleen Please select Netherlands
  • THERMACOTE CONSULTING CORP. LTD, PERE TOSHEV 2 2800 SANDANSKI BULGARIA Bulgaria
  • TINOX CHEMIE GMBH, LÜTTICHER STRAßE132 40547 DÜSSELDORF Germany
  • TioTech AS, Heiane 2b 5131 Nyborg Norway
  • Total Petrochemicals Antwerpen NV, Scheldelaan 4 2030 Antwerpen Belgium
  • Total Petrochemicals Feluy SA, Zone industrielle C 7181 Feluy Belgium
  • Treibacher Industrie AG, Auer-von-Welsbach-Straße 1 9330 Althofen Carinthia Austria
  • Tronox France SAS, 95 Rue du General De Gaulle 68800 Thann France
  • Tronox France SAS , 95 Rue du General De Gaulle 68800 Thann France
  • Tronox Pigment UK Limited, PO Box 26 LaPorte Road, Stallingborough DN41 8DP Grimsby Northeast Lincolnshire United Kingdom
  • Tronox Pigments (Holland) b.v., PROF. GERBRANDYWEG 2 3197KK ROTTERDAM-BOTLEK The Netherlands Netherlands
  • Tronox Pigments (Holland) B.V._OR1, PROF. GERBRANDYWEG 2 3197KK ROTTERDAM-BOTLEK The Netherlands Netherlands
  • TÜV SÜD Iberia S.A.U. (040), Ronda Can Fatjó, 13 08290 Cerdanyola del Vallès Barcelona Spain
  • TÜV SÜD Industrie Service GmbH, Westendstraße 199 80686 München Germany
  • UMCO GmbH, Georg-Wilhelm-Straße 187 21107 Hamburg Germany
  • UmEnA GmbH, Bachfeld 17 4211 Alberndorf Austria
  • UMICORE Galvanotechnik GmbH, 53-79 Klarenbergstrasse 73525 Schwäbisch Gmünd Germany
  • Umicore Thin Film Products AG, Alte Landstrasse 8 FL-9496 Balzers Liechtenstein
  • Valspar b.v., Zuiveringweg 89 8243 PE Lelystad Netherlands
  • Venator France SAS, 1 Rue des Garennes 62100 Calais France
  • Venator Germany GmbH, Dr.- Rudolf-Sachtleben Str. 4 47198 Duisburg Germany
  • Venator Germany GmbH - OR1, Dr.- Rudolf-Sachtleben Str. 4 47198 Duisburg Germany
  • VENATOR ITALY S.R.L., Localita Casone 1 58020 Scarlino GR Italy
  • VENATOR MATERIALS UK LIMITED, Titanium House Hanzard Drive TS22 5FD Wynyard Park United Kingdom
  • VENATOR MATERIALS UK LIMITED - OR2, Titanium House Hanzard Drive TS22 5FD Wynyard Park United Kingdom
  • Venator P&A Finland Oy, Titaanitie 28840 Pori Finland
  • Venator P&A Spain S.L., Poligono Industrial Nuevo Puerto Calle A s/n 21810 Palos de la Frontera (Huelva) Spain
  • Venator Pigments GmbH & Co. KG, Mühlstraße 118 65396 Walluf Germany
  • Venator Uerdingen GmbH, Rheinuferstraße 7–9 47829 Krefeld Germany
  • Videojet Technologies Europe B.V., Strijkviertel 39 3454 PJ De Meern Utrecht Netherlands
  • Vink+Co GmbH Handelsgesellschaft und Co.KG, Eichenhöhe 24 21255 Kakenstorf Germany
  • Vishay Electronic GmbH, Dr.-Felix-Zandman-Platz 1 95100 Selb Germany
  • Wacker Chemie AG, Hanns-Seidel-Platz 4 81737 Muenchen Germany
  • West Pharmaceutical Services Deutschland GmbH & Co. KG, Stolberger Straße 21-41 52249 Eschweiler Germany
  • West Pharmaceutical Services France S.A., 38, Rue Robert Degon 02170 Le Nouvion-en-Thierache France
  • WOOLWORTH GmbH, Formerstr.6 59425 Unna NRW Germany
  • WSP UK Ltd (OR4), WSP HOUSE 70 CHANCERY LANE WC2A 1AF LONDON United Kingdom
  • YKK (U.K.) LTD., Whitehouse Ind Estate WA7 3BW Runcorn United Kingdom
  • Yordas GmbH, Äußere Nürnberger Str. 6 91301 Forchheim Germany
  • ZANGAS Hoch-und Tiefbau GmbH, Schwindgasse 5/1/4 1040 Vienna Austria
  • Zebra A/S, Strandgade 71-73 1401 Copenhagen Denmark
  • [Confidential], [Confidential]
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77, Dublin, Ireland D02 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LTD, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • DSM Desotech bv, Slachthuisweg 30 3151 XN Hoek van Holland Netherlands
  • Envigo Consulting Limited, Woolley Road Alconbury PE28 4HS Huntingdon Cambridgeshire United Kingdom
  • Henkel Electronic Materials (Belgium) N.V., Nijverheidsstraat 7 2260 Westerlo Belgium
  • NetSun EU B.V., Blaak 40, Fifth Floor 3011 TA Rotterdam Netherlands
  • Only representative (No publishable name), null
  • SOLVAY SPECIALTY POLYMERS BELGIUM SA, rue de Ransbeek 310 1120 Brussels Belgium
  • TIGI Haircare GmbH, Hertzstraße 6 71083 Herrenberg Germany
  • [Confidential], [Confidential]

Substance names and other identifiers

Titanium dioxide
EC Inventory, Substance Evaluation - CoRAP, REACH pre-registration, Other, Cosmetic Products Regulation, Annex IV - Allowed Colorants, Cosmetic Products Regulation, Annex VI - Allowed UV Filters, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, FCM and Articles Regulation, Annex I - Authorised Substances, Workplace Signs - minimum requirements & signs on containers and pipes
titanium dioxide [in powder form containing 1 % or more of particles with aerodynamic diameter ≤ 10 μm]
CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
titanium dioxide; [in powder form containing 1 % or more of particles with aerodynamic diameter ≤ 10 μm]
C&L Inventory
biossido di titanio; [in polvere contenente ≥ 1 % di particelle con diametro aerodinamico ≤ 10 μm] (it)
C&L Inventory
diossidu tat-titanju;[f’forma ta’ trab li fiha 1 %jew aktar ta’ partiċelli b’dijametruajrudinamiku ta’ ≤10 μm] (mt)
C&L Inventory
dioxid de titan [sub formă de pulbere care conține 1 % sau mai mult particule cu un diametru aerodinamic ≤ 10 μm] (ro)
C&L Inventory
dioxyde de titane; [sous la forme d’une poudre contenant 1 % ou plus de particules d’un diamètre ≤ 10 μm] (fr)
C&L Inventory
ditlenek tytanu; [w postaci proszku o zawartości 1 % lub więcej cząstek o średnicy aerodynamicznej ≤ 10 μm] (pl)
C&L Inventory
Dióxido de titanio; [en forma de polvo que contenga el 1 % o más de partículas con un diámetro aerodinámico ≤ 10 μm] (es)
C&L Inventory
dióxido de titânio; [em pó, contendo 1% ou mais de partículas com diâmetro aerodinâmico ≤ 10 μm] (pt)
C&L Inventory
oxid titaničitý; [ve formě prášku obsahujícího 1 % nebo více částic o aerodynamickém průměru ≤ 10 μm] (cs)
C&L Inventory
oxid titaničitý; [vo forme prášku, ktorý obsahuje 1 % alebo vyšší podiel častíc s aerodynamickým priemerom ≤ 10 μm] (sk)
C&L Inventory
titaandioksiid; [pulbrina, mis sisaldab vähemalt 1 % ulatuses osakesi, mille aerodünaamiline läbimõõt on ≤ 10 μm] (et)
C&L Inventory
Titaanidioksidi; [jauheena, joka sisältää vähintään 1 prosenttia titaanidioksidihiukkasia, joiden aerodynaaminen halkaisija on ≤ 10 μm] (fi)
C&L Inventory
titandioxid; [i pulverform med et indhold på 1 % eller mere af titandioxid, der antager form som eller indgår i partikler, med en aerodynamisk diameter på ≤ 10 μm] (da)
C&L Inventory
Titandioxid; [in Pulverform mit mindestens 1 % Partikel mit aerodynamischem Durchmesser ≤ 10 μm] (de)
C&L Inventory
titandioxid;[i form av pulver som innehållerminst 1 % partiklarmed en aerodynamiskdiameter ≤ 10 μm] (sv)
C&L Inventory
titanijev dioksid; [u obliku praha koji sadržava najmanje 1 % čestica aerodinamičkog promjera ≤ 10 μm] (hr)
C&L Inventory
titaniumdioxide; [in poedervorm, bevattend: 1 % of meer deeltjes met een aërodynamische diameter ≤ 10 μm] (nl)
C&L Inventory
titano dioksidas[miltelių pavidalo, kuriosudėtyje yra ne mažiau kaip1 % dalelių, kurių aerodinaminisskersmuo ≤ 10 μm] (lt)
C&L Inventory
titanov dioksid;[v obliki prahu, ki vsebuje 1% ali več delcev z aerodinamičnimpremerom ≤ 10μm] (sl)
C&L Inventory
titán-dioxid;[legalább 1 %, legfeljebb 10μm aerodinamikai átmérőjűrészecskéket tartalmazópor formában] (hu)
C&L Inventory
titāna dioksīds; [tāda pulvera veidā, kas satur 1 % vai vairāk daļiņu ar aerodinamisko diametru ≤ 10 μm] (lv)
C&L Inventory
διοξείδιο του τιτανίου [σε μορφή σκόνης που περιέχει τουλάχιστον 1 % σωματίδια με αεροδυναμική διάμετρο ≤ 10 μm] (el)
C&L Inventory
титанов диоксид; [под формата на прах, съдържащ 1 % или повече частици с аеродинамичен диаметър ≤ 10 μm] (bg)
C&L Inventory
Titanium oxide (TiO2)
Other
diooxotitanium
C&L Inventory
dioxo titanium
Registration dossier
Dioxotitanium
C&L Inventory, Registration dossier
Dwutlenek tytanu, ditlenek tytanu
Registration dossier
Oxid titaničitý
C&L Inventory
R_JS_Dossier_Titanium_Dioxide
Registration dossier
Rutile (TiO2)
Registration dossier
Tiitanium Dioxide
Registration dossier
TiO2
Registration dossier
TiO2-R
Registration dossier
Titandioxid (in the form of Rutile Sand) 13463-67-7
C&L Inventory
titania in 1-methoxy-2-propanol
C&L Inventory
Titanium dioxide TiO2
Registration dossier
titanium dioxide white
Registration dossier
Titanium Dioxide, Anatase, Rutile
Registration dossier
Titanium oxide
C&L Inventory
Titanium(IV) Oxide
C&L Inventory, Registration dossier
Titanium(IV)oxide
Registration dossier
Titannium dioxide
C&L Inventory
Titaum dioxide
C&L Inventory
AERODISP®
Registration dossier
AEROPERL
Registration dossier
AEROXIDE TiO2
Registration dossier
AEROXIDE® TiO2
Registration dossier
ANATASA
Registration dossier
ANATASA 98% MIN
Registration dossier
ANATASA 98.5% MIN
Registration dossier
ANATASA A-X
Registration dossier
ANATASA BAJA EN NEOBIO
Registration dossier
ANATASA E
Registration dossier
ANATASA ENAMEL GRADE
Registration dossier
ANATASA FIBRA
Registration dossier
ANATASA GRADO ESMALTES
Registration dossier
ANATASA GRADO FRITA
Registration dossier
ANATASA I
Registration dossier
ANATASA PAPEL
Registration dossier
ANATASA R
Registration dossier
Anatase
Registration dossier
Anatase Titanium Dioxide
Registration dossier
biel tytanowa
Registration dossier
C47051
Registration dossier
C475001
Registration dossier
CathayCoat White TA41, TA42, TA45, TA46, TA49
Registration dossier
Cosmetica® Super White 9000SReflexTM Rutile Fine R-901DAutomotiveTM Dazzling White A-901S
Registration dossier
Cristal
Registration dossier
CSB
Registration dossier
CSP
Registration dossier
DHA-100
Registration dossier
DHA-130
Registration dossier
DIOXIDO DE TITANIO
Registration dossier
DIOXIDO DE TITANIO ANATASA
Registration dossier
DIOXIDO DE TITANIO DJ240
Registration dossier
DIOXIDO DE TITANIO DJ2400
Registration dossier
DIOXIDO DE TITANIO ORIGEN CHINA
Registration dossier
DIOXIDO DE TITANIO ORIGEN REPUBLICA CHECA
Registration dossier
DIOXIDO DE TITANIO ORIGEN RUSIA
Registration dossier
DIOXIDO DE TITANIO ORIGEN UKRANIA
Registration dossier
DIOXIDO DE TITANIO R-203
Registration dossier
DIOXIDO DE TITANIO R-221
Registration dossier
DIOXIDO DE TITANIO R-222
Registration dossier
DIOXIDO DE TITANIO R-223
Registration dossier
DIOXIDO DE TITANIO R-606
Registration dossier
DIOXIDO DE TITANIO R216
Registration dossier
DIOXIDO DE TITANIO R248
Registration dossier
DIOXIDO DE TITANIO R258
Registration dossier
DIOXIDO DE TITANIO R298
Registration dossier
DIOXIDO DE TITANIO R500
Registration dossier
DIOXIDO DE TITANIO R501
Registration dossier
DIOXIDO DE TITANIO R601
Registration dossier
DIOXIDO DE TITANIO R621
Registration dossier
DIOXIDO DE TITANIO RUTILO
Registration dossier
DIOXIDO DE TITANIO RUTILO R996
Registration dossier
Dwutlenek tytanu
Registration dossier
FerroTint White F31
Registration dossier
High Purity Titanium dioxide F31(B)HP
Registration dossier
HOMBITAN
Registration dossier
HTR-100AP
Registration dossier
HTR-100SA
Registration dossier
HTR-100W
Registration dossier
HTR-15Z
Registration dossier
KA-100
Registration dossier
KR-1000
Registration dossier
KR-2000
Registration dossier
KRONOS Titanium dioxide
Registration dossier
KRONOS TITANIUM DIOXIDE KA-10
Registration dossier
KRONOS TITANIUM DIOXIDE KR-310
Registration dossier
Kronox
Registration dossier
Lavanya Chaandani
Registration dossier
MPT-350
Registration dossier
MT(Micro Titanium Dioxide)
Registration dossier
MTW
Registration dossier
No specific trade name
Registration dossier
RFC
Registration dossier
Rutile
Registration dossier
Rutile Titanium Dioxide
Registration dossier
SACHTLEBEN
Registration dossier
SHT-R114
Registration dossier
SHT-R420
Registration dossier
SHT-R422
Registration dossier
SHT-R610
Registration dossier
SHT-R615
Registration dossier
SHT-R621
Registration dossier
SHT-R722
Registration dossier
SSP
Registration dossier
STR
Registration dossier
STR-100C
Registration dossier
STR-100C-LF
Registration dossier
STR-40C
Registration dossier
SUMTITAN
Registration dossier
SUMTITAN R-202
Registration dossier
SUMTITAN R-203
Registration dossier
SUMTITAN R-204
Registration dossier
SUMTITAN R-206
Registration dossier
T-Lite
Registration dossier
Tego
Registration dossier
Ti-Catalyst C-94
Registration dossier
Ti-Pure®
Registration dossier
Ti-Pure™
Registration dossier
Tiona
Registration dossier
Tiona(r)
Registration dossier
TiOx
Registration dossier
TiOx-220
Registration dossier
TiOx-230
Registration dossier
TiOx-270
Registration dossier
TiOx-271
Registration dossier
TiOx-280
Registration dossier
Tipure
Registration dossier
Titandioxid KA 100 (Anatase)
Registration dossier
Titandioxid R-Z (Rutile)
Registration dossier
TITANIO BIOSSIDO ANATASIO
Registration dossier
TITANIO BIOSSIDO ANATASIO BASSO NEOBIO
Registration dossier
TITANIO BIOSSIDO ANATASIO SCR
Registration dossier
TITANIO BIOSSIDO RUTILO
Registration dossier
TITANIO BIOSSIDO RUTILO 501
Registration dossier
TITANIO BIOSSIDO RUTILO 502
Registration dossier
TITANIO BIOSSIDO RUTILO 602
Registration dossier
TITANIO BIOSSIDO RUTILO 688
Registration dossier
TITANIO BIOSSIDO RUTILO 699
Registration dossier
TITANIO BIOSSIDO RUTILO LOMON R-996
Registration dossier
TITANIO BIOSSIDO RUTILO R-202
Registration dossier
TITANIO BIOSSIDO RUTILO R-203
Registration dossier
TITANIO BIOSSIDO RUTILO R-206
Registration dossier
TITANIO BIOSSIDO RUTILO R-248
Registration dossier
TITANIO BIOSSIDO RUTILO R-258
Registration dossier
TITANIO BIOSSIDO RUTILO R-298
Registration dossier
TITANIO BIOSSIDO RUTILO R02
Registration dossier
Titanium bioxide enamel grade GZ
Registration dossier
Titanium bioxide enamel grade LNB
Registration dossier
TITANIUM DIOXIDE 3328 USP
Registration dossier
Titanium dioxide anatase
Registration dossier
Titanium Dioxide Cotiox KA 100
Registration dossier
TITANIUM DIOXIDE ST-705SA
Registration dossier
TITANIUM DIOXIDE ST-705WD
Registration dossier
TITANIUM DIOXIDE ST-710EC
Registration dossier
TITANIUM DIOXIDE ST-710WD
Registration dossier
TITANIUM DIOXIDE ST-750EC
Registration dossier
titanium white
Registration dossier
TITANIX
Registration dossier
TITONE
Registration dossier
Tronox
Registration dossier
TTO-55(A)
Registration dossier
TTO-S-4
Registration dossier
TYTANPOL
Registration dossier
ULTRA FINE TITANIUM DIOXIDE ST-101T
Registration dossier
ULTRA FINE TITANIUM DIOXIDE ST-4
Registration dossier
ULTRA FINE TITANIUM DIOXIDE ST-410WB
Registration dossier
ULTRA FINE TITANIUM DIOXIDE ST-450
Registration dossier
ULTRA FINE TITANIUM DIOXIDE ST-450EC
Registration dossier
ULTRA FINE TITANIUM DIOXIDE ST-450SA
Registration dossier
ULTRA FINE TITANIUM DIOXIDE ST-450WD
Registration dossier
ULTRA FINE TITANIUM DIOXIDE ST-455
Registration dossier
ULTRA FINE TITANIUM DIOXIDE ST-455WB
Registration dossier
ULTRA FINE TITANIUM DIOXIDE ST-455WS
Registration dossier
ULTRA FINE TITANIUM DIOXIDE ST-457SA
Registration dossier
ULTRA FINE TITANIUM DIOXIDE ST-457WD
Registration dossier
ULTRA FINE TITANIUM DIOXIDE ST-485SA15
Registration dossier
ULTRA FINE TITANIUM DIOXIDE ST-486EFS
Registration dossier
ULTRA FINE TITANIUM DIOXIDE ST-495MC
Registration dossier
ULTRA FINE TITANIUM DIOXIDE ST-500
Registration dossier
ULTRA FINE TITANIUM DIOXIDE ST-550
Registration dossier
ULTRA FINE TITANIUM DIOXIDE ST-550R
Registration dossier
ULTRA FINE TITANIUM DIOXIDE ST-570
Registration dossier
ULTRA FINE TITANIUM DIOXIDE ST-6
Registration dossier
ULTRA FINE TITANIUM DIOXIDE STT-100H
Registration dossier
ULTRA FINE TITANIUM DIOXIDE STT-300
Registration dossier
ULTRA FINE TITANIUM DIOXIDE STT-30A-I
Registration dossier
ULTRA FINE TITANIUM DIOXIDE STT-30A-I-FS10
Registration dossier
ULTRA FINE TITANIUM DIOXIDE STT-30A-I-FS5
Registration dossier
ULTRA FINE TITANIUM DIOXIDE STT-30S
Registration dossier
ULTRA FINE TITANIUM DIOXIDE STV-455
Registration dossier
UV TITAN
Registration dossier
022-006-00-2
Index number
C&L Inventory
100292-32-8
CAS number
Other
101239-53-6
CAS number
Other
1025343-79-6
CAS number
Other
116788-85-3
CAS number
Other
12000-59-8
CAS number
Other
1205638-49-8
CAS number
Other
1236143-41-1
CAS number
Other
12701-76-7
CAS number
Other
12767-65-6
CAS number
Other
12789-63-8
CAS number
Other
1309-63-3
CAS number
Other
1344-29-2
CAS number
Other
13463-67-7
CAS number
EC Inventory, C&L Inventory, Substance Evaluation - CoRAP, Registration dossier, REACH pre-registration, Other, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Cosmetic Products Regulation, Annex IV - Allowed Colorants, Cosmetic Products Regulation, Annex VI - Allowed UV Filters, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, FCM and Articles Regulation, Annex I - Authorised Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, Workplace Signs - minimum requirements & signs on containers and pipes, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
1377807-26-5
CAS number
Other
1393678-13-1
CAS number
Other
1400974-17-5
CAS number
Other
1415904-10-7
CAS number
Other
1456717-15-9
CAS number
Other
158518-86-6
CAS number
Other
1613035-81-6
CAS number
Other
1613512-65-4
CAS number
Other
1615226-10-2
CAS number
Other
1631962-20-3
CAS number
Other
1644062-60-1
CAS number
Other
1809260-52-3
CAS number
Other
185323-71-1
CAS number
Other
185828-91-5
CAS number
Other
1867123-83-8
CAS number
Other
188357-76-8
CAS number
Other
188357-79-1
CAS number
Other
1911573-09-5
CAS number
Other
195740-11-5
CAS number
Other
2052159-56-3
CAS number
Other
2052276-52-3
CAS number
Other
2055821-10-6
CAS number
Other
2089284-84-2
CAS number
Other
2097593-12-7
CAS number
Other
2101768-00-5
CAS number
Other
2135942-54-8
CAS number
Other
221548-98-7
CAS number
Other
224963-00-2
CAS number
Other
246178-32-5
CAS number
Other
252962-41-7
CAS number
Other
37230-92-5
CAS number
Other
37230-94-7
CAS number
Other
37230-95-8
CAS number
Other
37230-96-9
CAS number
Other
39320-58-6
CAS number
Other
39360-64-0
CAS number
Other
39379-02-7
CAS number
Other
416845-43-7
CAS number
Other
494848-07-6
CAS number
Other
494848-23-6
CAS number
Other
494851-77-3
CAS number
Other
494851-98-8
CAS number
Other
52624-13-2
CAS number
Other
55068-84-3
CAS number
Other
55068-85-4
CAS number
Other
552316-51-5
CAS number
Other
62338-64-1
CAS number
Other
767341-00-4
CAS number
Other
859528-12-4
CAS number
Other
861455-28-9
CAS number
Other
861455-30-3
CAS number
Other
866531-40-0
CAS number
Other
946525-05-9
CAS number
Other
97929-50-5
CAS number
Other
98084-96-9
CAS number
Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 4 studies submitted
  • 4 studies processed
C Physical state at 20°C and 1013 hPa
Solid (100%) [4]
C Form
Crystalline (75%), Solid: nanomaterial (25%) [4]
C Odour
Odourless (100%) [4]
C Substance type
Inorganic (100%) [4]

Type of Study provided
Studies with data
Key study 1 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 12 summaries submitted
  • 12 summaries processed
Physical state at 20°C and 1013 hPa
Solid (100%)
Form
Solid: nanomaterial (92%), Solid (8%)
Colour
white (100%)

Melting/freezing point

Study results
  • 4 studies submitted
  • 3 studies processed
R Melting / freezing point
1 560 - 1 850 °C [5]

Type of Study provided
Studies with data
Key study 1 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Boiling point

Study results
  • 4 studies submitted
  • 4 studies processed
R Boiling point
2 500 - 3 000 °C @ 101.3 - 101.325 kPa [4]

Type of Study provided
Studies with data
Key study 1 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Density

Study results
  • 7 studies submitted
  • 4 studies processed
R Density
3.9 - 4.26 g/cm³ @ 20 °C [3]
R Relative density
3.9 - 4.26 [2]

Type of Study provided
Studies with data
Key study 1 3
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Vapour pressure

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Partition coefficient

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified
Exposure cons.
Other
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Water solubility

Study results
  • 21 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 7 1
Supporting study 10 2
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Solubility in organic solvents / fat solubility

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Surface tension

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified
Exposure cons.
Other
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 11 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 6 studies submitted
  • 2 studies processed
C Interpretation of results
GHS criteria not met (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 4
Exposure cons.
Other
C Summaries
  • 12 summaries submitted
  • 12 summaries processed
Flammability
Not classified (100%)

Explosiveness

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
C Summaries
  • 12 summaries submitted
  • 12 summaries processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
C Summaries
  • 12 summaries submitted
  • 12 summaries processed
Oxidising
Non oxidising (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified
Exposure cons.
Other
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified
Exposure cons.
Other
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 11 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 11 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 11 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 11 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 51 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 12 3
Weight of evidence 3 1
Other 32
Data waiving
no waivers
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Study results
  • 27 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 3
Weight of evidence 5 2
Other 15 2
Data waiving
no waivers
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Adsorption/desorption

Study results
  • 11 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 3
Supporting study 2 2
Weight of evidence 1
Other 3
Data waiving
no waivers
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No hazard identified (1)
Intermittent releases (freshwater) No hazard identified (1)
Marine water No hazard identified (1)
Intermittent releases (marine water) No hazard identified (1)
Sewage treatment plant (STP) No hazard identified (1)
Sediment (freshwater) No hazard identified (1)
Sediment (marine water) No hazard identified (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil No hazard identified (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 40 studies submitted
  • 6 studies processed
P/RResults
LC50 (14 days) 870 - 1 100 µg/L [5]
LC50 (72 h) 1 mg/L [1]
NOEC (14 days) 870 - 1 100 µg/L [5]

Type of Study provided
Studies with data
Key study
Supporting study 5
Weight of evidence 15 1
Other 19
Data waiving
no waivers
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 23 studies submitted
  • 3 studies processed
P/RResults
NOEC (6 days) 80 - 160 mg/L [6]
NOEC (4 days) 80 - 160 mg/L [5]
LOEC (6 days) 160 mg/L [1]
LOEC (4 days) 160 mg/L [1]
LC50 (6 days) 160 mg/L [2]

Type of Study provided
Studies with data
Key study
Supporting study 3
Weight of evidence 10 1
Other 9
Data waiving
no waivers
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 74 studies submitted
  • 5 studies processed
P/RResults
EC50 (72 h) 3.58 - 100 mg/L [3]
EC50 (48 h) 2.41 - 103.9 mg/L [12]

Type of Study provided
Studies with data
Key study
Supporting study 7
Weight of evidence 23 1
Other 43
Data waiving
no waivers
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 19 studies submitted
  • 5 studies processed
P/RResults
NOEC (28 days) 100 mg/L [6]
NOEC (21 days) 5 mg/L [2]
NOEC (10 days) 1 mg/L [1]
LOEC (21 days) 5 mg/L [1]

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence 8 1
Other 7 1
Data waiving
no waivers
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 37 studies submitted
  • 3 studies processed
P/RResults
EC50 (72 h) 100 mg/L [2]
NOEC (32 days) 1 mg/L [1]
NOEC (72 h) 100 mg/L [2]
EC10 (72 h) 2 mg/L [1]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 7 1
Other 29
Data waiving
no waivers
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Study results
  • 8 studies submitted
  • 2 studies processed
P/RResults
EC50 (7 days) 100 mg/L [2]
NOEC (7 days) 100 mg/L [3]

Type of Study provided
Studies with data
Key study 1 1
Supporting study 1
Weight of evidence
Other 5
Data waiving
no waivers
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to microorganisms

Study results
  • 43 studies submitted
  • 5 studies processed
P/RResults
EC50 (3 h) 1 g/L [4]
NOEC (3 h) 1 g/L [5]
LOEC (3 h) 1 g/L [1]

Type of Study provided
Studies with data
Key study
Supporting study 9
Weight of evidence 4 1
Other 29
Data waiving
no waivers
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 16 studies submitted
  • 6 studies processed
P/RResults
NOEC (28 days) 851.8 mg/kg sediment dw [2]
NOEC (28 days) 100 mg/L [6]
NOEC (21 days) 851.1 mg/kg sediment dw [1]
EC10 (28 days) 851.8 - 1 000 mg/kg sediment dw [4]
EC50 (28 days) 851.8 - 1 000 mg/kg sediment dw [4]

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence 6 1 2
Other 5
Data waiving
no waivers
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 28 studies submitted
  • 9 studies processed
P/RResults
NOEC (56 days) 400 - 1 000 mg/kg soil dw [6]
NOEC (28 days) 400 - 1 000 mg/kg soil dw [10]
NOEC (14 days) 1 g/kg soil dw [3]
EC10 (28 days) 1 g/kg soil dw [4]
EC50 (28 days) 1 g/kg soil dw [4]

Type of Study provided
Studies with data
Key study
Supporting study 8
Weight of evidence 8 1
Other 11
Data waiving
no waivers
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 12 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 2 1
Weight of evidence
Other 7
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 31 studies submitted
  • 7 studies processed
P/RResults
NOEC (84 days) 1 g/kg soil dw [15]
NOEC (14 days) 44 - 100 mg/kg soil dw [10]
LOEC (14 days) 67 - 100 mg/kg soil dw [3]
EC10 (14 days) 51.7 mg/kg soil dw [1]
EC50 (14 days) 100 mg/kg soil dw [3]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 5 1 1 2
Other 22
Data waiving
no waivers
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 18 studies submitted
  • 5 studies processed
P/RResults
NOEC (28 days) 21 - 100 mg/kg soil dw [5]
EC10 (28 days) 100 mg/kg soil dw [2]
EC50 (28 days) 100 mg/kg soil dw [2]

Type of Study provided
Studies with data
Key study
Supporting study 3
Weight of evidence 4 1 1
Other 9
Data waiving
no waivers
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 11 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 48 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence 39
Other 9
Data waiving
no waivers
Study data: dermal absorption
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other 3
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation potential:
No bioaccumulation potential

Acute toxicity

Study results
oral
  • 8 studies submitted
  • 6 studies processed
P/RResults
LD50 2 000 - 25 000 mg/kg bw (rat) [5]
LD50 5 000 mg/kg bw (mouse) [1]
M/CInterpretations of results
Practically nontoxic [5]

Type of Study provided
oral
Studies with data
Key study
Supporting study
Weight of evidence 6 1
Other 1
Data waiving
no waivers
inhalation
  • 11 studies submitted
  • 2 studies processed
P/RResults
LC50 (4 h) 3.43 - 6.82 mg/L air (rat) [3]
M/CInterpretations of results
Practically nontoxic [2]

inhalation
Studies with data
Key study 2
Supporting study 3
Weight of evidence 1
Other 5
Data waiving
no waivers
dermal
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
other routes
  • 7 studies submitted
  • 0 studies processed

No automatically processable data submitted

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other 7
Data waiving
no waivers
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Irritation / corrosion

Study results
Study data: skin
  • 19 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 3
Supporting study 14
Weight of evidence 1
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study 3
Weight of evidence 1
Other 3
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 12 summaries submitted
  • 12 summaries processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No adverse effect observed (not irritating)

Sensitisation

Study results
Study data: skin
  • 10 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2
Supporting study 2
Weight of evidence 3 1
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: respiratory
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study 2
Weight of evidence 1
Other 1
Data waiving
no waivers
M/C Summaries
  • 12 summaries submitted
  • 12 summaries processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 13 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Study data: oral
Studies with data
Key study
Supporting study
Weight of evidence 5
Other 8
Data waiving
no waivers
Study data: inhalation
  • 26 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study
Supporting study 12
Weight of evidence 4 1
Other 9
Data waiving
no waivers
Study data: dermal
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study 1
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Genetic toxicity

Study results
Study data: in vitro
  • 103 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study
Supporting study
Weight of evidence 81 3
Other 19
Data waiving
no waivers
Study data: in vivo
  • 60 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study
Supporting study
Weight of evidence 39 2
Other 19
Data waiving
no waivers
M/C Summaries
  • 12 summaries submitted
  • 12 summaries processed
Toxicity - InVitro
No adverse effect observed (negative)
Toxicity - InVivo
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 12 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence 4 1
Other 4
Data waiving
no waivers
Summaries
  • 12 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1 1
Supporting study 4
Weight of evidence
Other 3
Data waiving
no waivers
Study data: developmental
  • 16 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 6
Supporting study 1
Weight of evidence 2
Other 6
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: other studies
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other 3
Data waiving
no waivers
M/C Summaries
  • 12 summaries submitted
  • 12 summaries processed
Effect on developmental toxicity
Oral route:
No adverse effect observed NOAEL 1 000 mg/kg bw/day (subchronic, rat)

Neurotoxicity

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 4
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant