Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

  • EC / List name:
  • IUPAC name: tetrasodium 4-amino-5-hydroxy-3,6-bis[(E)-2-{4-[2-(sulfonatooxy)ethanesulfonyl]phenyl}diazen-1-yl]naphthalene-2,7-disulfonate
  • Substance names and other identifiers
EC / List no.:
241-164-5
CAS no.:
17095-24-8
Index number:
Molecular formula:
C26H21N5Na4O19S6
SMILES:
[Na+].[Na+].[Na+].[Na+].NC1=C(\N=N\C2=CC=C(C=C2)S(=O)(=O)CCOS([O-])(=O)=O)C(=CC2=C1C(O)=C(\N=N\C1=CC=C(C=C1)S(=O)(=O)CCOS([O-])(=O)=O)C(=C2)S([O-])(=O)=O)S([O-])(=O)=O
InChI:
InChI=1S/C26H25N5O19S6.4Na/c27-23-22-15(13-20(53(37,38)39)24(23)30-28-16-1-5-18(6-2-16)51(33,34)11-9-49-55(43,44)45)14-21(54(40,41)42)25(26(22)32)31-29-17-3-7-19(8-4-17)52(35,36)12-10-50-56(46,47)48;;;;/h1-8,13-14,32H,9-12,27H2,(H,37,38,39)(H,40,41,42)(H,43,44,45)(H,46,47,48);;;;/q;4*+1/p-4/b30-28+,31-29+;;;
Type of substance:
UVCB
Origin:
Organic
Registered compositions:
22
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the classification provided by companies to ECHA in CLP notifications this substance may cause allergy or asthma symptoms or breathing difficulties if inhaled, may cause an allergic skin reaction, causes eye irritation and may cause respiratory irritation.

Breakdown of all 199 C&L notifications submitted to ECHA

Resp. Sens. 1 H334
Skin Sens. 1 H317
Eye Irrit. 2 H320
STOT SE 3 H335
Not Classified
Acute Tox. 3 H302
Eye Dam. 1 H318
Eye Irrit. 2 H319
Aquatic Chronic 3 H412
Skin Irrit. 2 H315
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://chesar.echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://chesar.echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://chesar.echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • Ss
There is broad agreement in that a majority of data submitters agree this substance is Skin sensitising (94.47% of CLP notifications).
  • Sr
There is broad agreement in that a majority of data submitters agree this substance is Respiratory sensitising (95.48% of CLP notifications).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 23 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: textile treatment products and dyes.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use.

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles, high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding) and calendering operations.

Release to the environment of this substance can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal). Other release to the environment of this substance is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

This substance can be found in products with material based on: fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper) and leather (e.g. gloves, shoes, purses, furniture).

This substance is used in the following products: textile treatment products and dyes and coating products.

This substance is used for the manufacture of: textile, leather or fur and wood and wood products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, treatment of articles by dipping and pouring, roller or brushing applications, mixing in open batch processes, transfer of substance into small containers and the low energy manipulation of substances bound in materials or articles.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance is used in the following products: textile treatment products and dyes, leather treatment products, inks and toners, laboratory chemicals and paper chemicals and dyes.

This substance is used in the following activities or processes at workplace: transfer of chemicals, mixing in open batch processes, transfer of substance into small containers and laboratory work.

Release to the environment of this substance can occur from industrial use: formulation of mixtures and formulation in materials.

This substance is used in the following products: textile treatment products and dyes and inks and toners.

This substance is used for the manufacture of: textile, leather or fur and pulp, paper and paper products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, treatment of articles by dipping and pouring, transfer of substance into small containers, roller or brushing applications, the low energy manipulation of substances bound in materials or articles and calendering operations.

Release to the environment of this substance can occur from industrial use: in the production of articles.

This substance is used in the following activities or processes at workplace: closed batch processing in synthesis or formulation, transfer of chemicals, batch processing in synthesis or formulation with opportunity for exposure, mixing in open batch processes, transfer of substance into small containers and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

ECHA has no data from registration dossiers on the precautionary measures for using this substance. Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • ANCHEMA Spółka z ograniczoną odpowiedzialnością Spółka Komandytowa, 25 Belwederska PL99-100 Łęczyca Łódzkie Poland
  • Archroma Germany GmbH, Kasteler Str. 45 65203 Wiesbaden Germany
  • ARCHROMA IBÉRICA, S.L., ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain
  • AUXICOLOR S.L., PISUERGA,38 08223 TERRASSA BARCELONA-CATALUNYA Spain
  • BLENDWELL SA, rue Benoît, 50 Zoning Industriel B-7370 Dour Belgium
  • ChAR Consultancy EOOD, Kırdjali bulvard Bulgaria 37, blok 51 6600 Kırdjali Kırdjali Bulgaria
  • CHROMATOURGIA TRIPOLEOS SA, SCHIMATARI 32009 SCHIMATARI VIOTIAS Greece
  • DyStar Colours Distribution GmbH, Am Prime-Parc 12 65479 Raunheim Germany
  • Everlight Europe B.V., Rivium Boulevard 224 2909LK Capelle a/d Ijssel Netherlands
  • Global Product Compliance (Europe) AB, IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden
  • Kem Color S.p.A., Str. della Cebrosa 58 10036 Settimo Torinese Torino Italy
  • KYKEHELLAS S.A, 2 km Sindos-Halastra, P.O Box 38 57400 Sindos Greece Greece
  • LAMBROCHIMICA S.R.L., VIA DELLA MOSCOVA 10 20121 MILANO Italy
  • Luxcontrol S.A. (OR45), 1, Avenue des Terres Rouges 4004 Esch-sur-Alzette Luxembourg
  • Only representative (No publishable name), null
  • Reach & Colours s.r.o, Thunovská 196/19 Malá Strana 118 00 Prague Czech Republic
  • Reach & Colours Trade Kft, Levente u. 14/a 2161 Csomád Hungary
  • REACH GLOBAL SERVICES S.A., Rond Point Schuman, 6 B-1040 Brussels Belgium
  • REACH&Colours Kft, Petofi Sandor utca 11 I Em. 4 1052 Budapest Hungary
  • SPGPrints B.V., Raamstraat 1-3 5831 AT Boxmeer Netherlands
  • TEXTILCOLOR GmbH (OR), Schlossgartenstrasse 2 72793 Pfullingen Baden-Wuerttemberg Germany
  • Triade B.V., Dijkweg 159 2675 AD Honselersdijk Netherlands
  • Yorkshire Farben GmbH, Mevissenstrasse 72 D-47803 Krefeld Germany

Substance names and other identifiers

Tetrasodium 4-amino-5-hydroxy-3,6-bis[[4-[[2-(sulphonatooxy)ethyl]sulphonyl]phenyl]azo]naphthalene-2,7-disulphonate
EC Inventory, REACH pre-registration
2,7-Naphthalenedisulfonic acid, 4-amino-5-hydroxy-3,6-bis[2-[4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]diazenyl]-, sodium salt (1:4)
Other
4-amino-5-hydroxy-3,6-bis[(E)-(4-{[2-(sulfooxy)ethyl]sulfonyl}phenyl)diazenyl]-naphthalene-2,7-disulfonic acid, sodium salt
C&L Inventory
C. I. Reactive Black 5
Registration dossier
C.I. Reactive Black 5
Registration dossier
Everzol SR28
Registration dossier
Reaction product of 4-Amino-5-hydroxynaphthalene-2,7-disulfonic acid sodium salt and diazotized 2-[(4-Aminophenyl)sulfonyl]ethyl hydrogen sulfate
Registration dossier
Reaction product of 4-Amino-5-hydroxynaphthalene-2,7-disulfonic acid sodium salt anddiazotized 2-[(4-Aminophenyl)sulfonyl]ethyl hydrogen sulfate
Registration dossier
Reaction products of 4-amino-5-hydroxynaphthalene-2,7-disulfonic acid, coupled twice with diazotized 2-[(4-aminophenyl)sulfonyl]ethyl hydrogen sulfate, sodium salts
Registration dossier
Reactive Black 005
Registration dossier
Reactive Black 5
C&L Inventory, Registration dossier
tetrasodium (6E)-4-amino-5-oxo-3-[4-(2-sulfonatooxyethylsulfonyl)phenyl]diazenyl-6-[[4-(2-sulfonatooxyethylsulfonyl)phenyl]hydrazinylidene]naphthalene-2,7-disulfonate
C&L Inventory
tetrasodium (6E)-4-amino-5-oxo-3-[[4-(2-sulfonatooxyethylsulfonyl)phenyl]diazenyl]-6-[[4-(2-sulfonatooxyethylsulfonyl)phenyl]hydrazinylidene]naphthalene-2,7-disulfonate
C&L Inventory
Tetrasodium (6Z)-4-amino-5-oxo-3-[4-(2-sulfonatooxyethylsulfonyl)phenyl] diazenyl-6-[[4-(2- sulfonatooxyethylsulfonyl)phenyl]hydrazinylidene]naphthalene-2,7-disulfonate
C&L Inventory
tetrasodium (6Z)-4-amino-5-oxo-3-[4-(2-sulfonatooxyethylsulfonyl)phenyl]diazenyl-6-[[4-(2-sulfonatooxyethylsulfonyl)phenyl]hydrazinylidene]naphthalene-2,7-disulfonate
C&L Inventory
tetrasodium 4-amino-5-hydroxy-3,6-bis[(4-{[2-(sulfonatooxy) ethyl]sulfonyl}phenyl)diazenyl]naphthalene-2,7-disulfonate
Registration dossier
tetrasodium 4-amino-5-hydroxy-3,6-bis[(4-{[2-(sulfonatooxy)ethyl]sulfonyl}phenyl)
C&L Inventory
tetrasodium 4-amino-5-hydroxy-3,6-bis[(4-{[2-(sulfonatooxy)ethyl]sulfonyl}phenyl)diazenyl]naphthalene-2,7-disulfonate
C&L Inventory, Registration dossier
tetrasodium 4-amino-5-hydroxy-3,6-bis[(E)-2-{4-[2-(sulfonatooxy)ethanesulfonyl]phenyl}diazen-1-yl]naphthalene-2,7-disulfonate
Registration dossier, Other
TETRASODIUM 4-AMINO-5-HYDROXY-3,6-BIS[[4-[[2-(SULPHONATOOXY)ETHYL]SULPHONYL]PHENYL]AZO]NAPHTALENE-2,7-DISLPHONATE
C&L Inventory
tetrasodium 4-amino-5-oxo-3-[[4-(2-sulfonatooxyethylsulfonyl)phenyl]diazenyl]-6-[[4-(2-sulfonatooxyethylsulfonyl)phenyl]hydrazinylidene]naphthalene-2,7-disulfonate
C&L Inventory
2,7-Naphthalenedisulfonic acid,4-amino-5-hydroxy-3,6-bis((4-((2-(sulfatooxy)ethyl)sulfonyl)phenyl)az o)-,tetrasodium salt (9CI)
Registration dossier
2,7-Naphthalenedisulfonic acid,4-amino-5-hydroxy-3,6-bis((p-((2-hydroxyethyl)sulfonyl)phenyl)azo)-,3 ,6-bis (hydrogen sulfate)(ester), tetrasodium salt (8CI)
Registration dossier
2,7-Naphthalindisulfonsaeure,4-amino-5-hydroxy-3,6-bis((4-((2-(sulfooxy)et hyl)sulfonyl)phenyl)azo)-,tetranatriumsalz
Registration dossier
Cavalite Black B (R)
Registration dossier
Celmazol Black B (R)
Registration dossier
Diamira Black B (R)
Registration dossier
Drimarene Black R/K 3B (R)
Registration dossier
Jalkazol Black- B
Registration dossier
Jettex R Schwarz BN E-0
Registration dossier
Jettex R Schwarz BN L-0
Registration dossier
Primazin Black BN (R)
Registration dossier
Realan Blau EHF
Registration dossier
Realan Marine EHF
Registration dossier
Realan Marineblau BG
Registration dossier
Realan Schwarz EHF
Registration dossier
Realan Schwarz G fl.40%
Registration dossier
Realan Schwarz M
Registration dossier
Remazol Black GF (R)
Registration dossier
Remazol Blau RGB
Registration dossier
Remazol Blau RR
Registration dossier
Remazol Carbon RGB
Registration dossier
Remazol Marine RGB 150%
Registration dossier
Remazol Marineblau R-UN
Registration dossier
Remazol Marineblau RT
Registration dossier
Remazol Schwarz DEN fl. 50%
Registration dossier
Remazol Schwarz E conc gran
Registration dossier
Remazol Schwarz NF-A
Registration dossier
Remazol Schwarz OA fl
Registration dossier
Remazol Tiefschwarz GWF
Registration dossier
Remazol Tiefschwarz N 150%
Registration dossier
Remazol Tiefschwarz RGB
Registration dossier
Remazol-Schwarz B (R)
Registration dossier
Sumifix Black B (R)
Registration dossier
1208234-88-1
Deleted CAS number
Other
12225-25-1
Deleted CAS number
Other
136511-39-2
Deleted CAS number
Other
17095-24-8
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other
188735-39-9
Deleted CAS number
Other
403597-90-0
Deleted CAS number
Other
494769-17-4
Deleted CAS number
Other
72528-69-9
Deleted CAS number
Other
90598-98-4
Deleted CAS number
Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Data not provided by the registrant

Melting/freezing point

Data not provided by the registrant

Boiling point

Data not provided by the registrant

Density

Data not provided by the registrant

Vapour pressure

Data not provided by the registrant

Partition coefficient

Data not provided by the registrant

Water solubility

Data not provided by the registrant

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Data not provided by the registrant

Flash point

Data not provided by the registrant

Auto flammability

Data not provided by the registrant

Flammability

Data not provided by the registrant

Explosiveness

Data not provided by the registrant

Oxidising

Data not provided by the registrant

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Data not provided by the registrant

Viscosity

Data not provided by the registrant

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Data not provided by the registrant

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Data not provided by the registrant

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Data not provided by the registrant

Bioaccumulation: aquatic / sediment

Data not provided by the registrant

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Data not provided by the registrant

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

Data not provided by the registrant

Short–term toxicity to fish

Data not provided by the registrant

Long–term toxicity to fish

Data not provided by the registrant

Short–term toxicity to aquatic invertebrates

Data not provided by the registrant

Long–term toxicity to aquatic invertebrates

Data not provided by the registrant

Toxicity to aquatic algae and cyanobacteria

Data not provided by the registrant

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Data not provided by the registrant

Sediment toxicity

Data not provided by the registrant

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Data not provided by the registrant

Toxicity to terrestrial arthropods

Data not provided by the registrant

Toxicity to terrestrial plants

Data not provided by the registrant

Toxicity to soil microorganisms

Data not provided by the registrant

Toxicity to birds

Data not provided by the registrant

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

Data not provided by the registrant

Toxicokinetics, metabolism, and distribution

Data not provided by the registrant

Acute toxicity

Data not provided by the registrant

Irritation / corrosion

Data not provided by the registrant

Sensitisation

Data not provided by the registrant

Repeated dose toxicity

Data not provided by the registrant

Genetic toxicity

Data not provided by the registrant

Carcinogenicity

Data not provided by the registrant

Toxicity to reproduction

Data not provided by the registrant

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant