Brief Profile

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

No image available
EC / List no.:
270-093-2
CAS no.:
68410-97-9
Index number:
649-332-00-3
Molecular formula:
SMILES:
InChI:
Type of substance:
UVCB
Origin:
Petroleum product
Registered compositions:
3
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP01) approved by the European Union, this substance may be fatal if swallowed and enters airways, may cause genetic defects and may cause cancer.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance is very toxic to aquatic life, is very toxic to aquatic life with long lasting effects, is an extremely flammable liquid and vapour, is harmful if swallowed, is harmful if inhaled, causes skin irritation and may cause drowsiness or dizziness.

Breakdown of all 166 C&L notifications submitted to ECHA

Asp. Tox. 1 H304 Harmonised Classification
Muta. 1B H340 Harmonised Classification
Carc. 1B H350 Harmonised Classification
Flam. Liq. 1 H224
Skin Irrit. 2 H315
STOT SE 3 H336
Aquatic Acute 1 H400
Aquatic Chronic 1 H410
Acute Tox. 4 H302
Acute Tox. 4 H332
Flam. Liq. 3 H226
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • C
Officially recognised in the EU as Carcinogenic (Harmonised C&L).
  • C
There is broad agreement in that a majority of data submitters agree this substance is Carcinogenic (60.84% of CLP notifications).
  • M
Officially recognised in the EU as Mutagenic (Harmonised C&L).
  • M
There is broad agreement in that a majority of data submitters agree this substance is Mutagenic (60.84% of CLP notifications).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 0 active registrations under REACH, 2 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation but is not currently being manufactured in and / or imported to the European Economic Area.

This substance is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: fuels, air care products, anti-freeze products, coating products, lubricants and greases, washing & cleaning products and welding & soldering products.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids), indoor use as processing aid and outdoor use as processing aid.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the types of manufacture using this substance.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure and closed batch processing in synthesis or formulation.

Other release to the environment of this substance is likely to occur from: indoor use as processing aid, outdoor use as processing aid, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and laboratory work.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals and rubber products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and laboratory work.

Release to the environment of this substance can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), in processing aids at industrial sites, as processing aid, of substances in closed systems with minimal release, in the production of articles, as processing aid and for thermoplastic manufacture.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: keep away from heat, sparks, open flames and/or hot surfaces – No smoking; obtain special instructions before use; avoid release to the environment; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If swallowed: immediately call a poison center or doctor/physician. Do not induce vomiting.

Storage statements

Store this substance in a well-ventilated place and keeping container tightly closed.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • INTERTEK FRANCE, ZAC Ecoparc II 27400 HEUDEBOUVILLE France
  • OLTCHIM SA, Uzinei 1 240050 Ramnicu Valcea Valcea Romania

Substance names and other identifiers

[A complex combination of hydrocarbons obtained by the distillation of products from the light distillate hydrotreating process. It consists of hydrocarbons having carbon numbers predominantly in the range of C6 through C9 and boiling in the range of approximately 3°C to 194°C (37°F to 382°F).]
A complex combination of hydrocarbons obtained by the distillation of products from the light distillate hydrotreating process. It consists of hydrocarbons having carbon numbers predominantly in the range of C6 through C9 and boiling in the range of approximately 3°C to 194°C (37°F to 382°F).
C&L Inventory
Distillates (petroleum), light distillate hydrotreating process, low-boiling
EC Inventory, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances
Distillates (petroleum), light distillate hydrotreating process, low-boiling
A complex combination of hydrocarbons obtained by the distillation of products from the light distillate hydrotreating process. It consists of hydrocarbons having carbon numbers predominantly in the range of C6 through C9 and boiling in the range of approximately 3°C to 194°C (37°F to 382°F).
C&L Inventory, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances
Distillates (petroleum), light distillate hydrotreating process, low-boiling; Low boiling point hydrogen treated naphtha [A complex combination of hydrocarbons obtained by the distillation of products from the light distillate hydrotreating process. It consists of hydrocarbons having carbon numbers predominantly in the range of C6 through C9 and boiling in the range of approximately 3 o C to 194 o C (37 °F to 382 °F).]
A complex combination of hydrocarbons obtained by the distillation of products from the light distillate hydrotreating process. It consists of hydrocarbons having carbon numbers predominantly in the range of C6 through C9 and boiling in the range of approximately 3°C to 194°C (37°F to 382°F).
Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work
Distillates, petroleum, light distillate hydrotreating process, low-boiling
A complex combination of hydrocarbons obtained by the distillation of products from the light distillate hydrotreating process. It consists of hydrocarbons having carbon numbers predominantly in the range of C6 through C9 and boiling in the range of approximately 3°C to 194°C (37°F to 382°F).
Other
Light distillate hydrotreater stabilizer overhead liquid
A complex combination of hydrocarbons obtained by the distillation of products from the light distillate hydrotreating process. It consists of hydrocarbons having carbon numbers predominantly in the range of C6 through C9 and boiling in the range of approximately 3°C to 194°C (37°F to 382°F).
Other
Low boiling point hydrogen treated naphtha
A complex combination of hydrocarbons obtained by the distillation of products from the light distillate hydrotreating process. It consists of hydrocarbons having carbon numbers predominantly in the range of C6 through C9 and boiling in the range of approximately 3°C to 194°C (37°F to 382°F).
C&L Inventory
(Keerulise koostisega süsivesinike segu, mis saadakse kerge destillaadi hüdrogeenimisproduktide destillatsioonil. Koosneb süsivesinikest, mille süsiniku aatomite arv on valdavalt vahemikus C6 kuni C9, ning on keemistemperatuuriga umbes 3°C kuni 194 °C.) (et)
C&L Inventory
(Složeni sastav ugljikovodika dobiven destilacijom proizvoda iz postupka hidroobrade lakog destilata. Sastoji se od ugljikovodika koji imaju broj ugljikovih atoma pretežito u području od C6 do C9 i vriju u području približno od 3 °C do 194 °C.) (hr)
C&L Inventory
[Kompleks blanding av hydrokarboner dannet ved destillasjon av produkter fra hydrogenbehandling av lett destillat. Består av hydrokarboner, hovedsakelig C6 til C9, med omtrentlig kokepunktsintervall fra 3 °C til 194 °C (37 °F til 382 °F).] (no)
C&L Inventory
[Kompleksna kombinacija ogljikovodikov dobljena z destilacijo produktov iz procesa obdelave lahkega destilata z vodikom. Sestoji iz ogljikovodikov s številom ogljikovih atomov pretežno v območju med C6 in C9 ter ima vrelišče v območju približno med 3 °C in 194 °C.] (sl)
C&L Inventory
[komplexe Kombination von Kohlenwasserstoffen, erhalten durch Destillation von Produkten aus der Wasserstoffbehandlung von leichtem Destillat; besteht aus Kohlenwasserstoffen mit Kohlenstoffzahlen überwiegend im Bereich von C6 bis C9 mit einem Siedebereich von etwa 3 °C bis 194 °C] (de)
C&L Inventory
[Komplexná zmes uhľovodíkov získavaná destiláciou z produktov hydrogenácie ľahkého destilátu. Pozostáva z uhľovodíkov s počtom atómov uhlíka prevažne v rozmedzí od C6 do C9. Má teplotu varu v rozmedzí približne od 3 °C do 194 °C.] (sk)
C&L Inventory
[O combinaţie complexă de hidrocarburi obţinute prin distilarea distilatului uşor de la procesul de hidrotratare. Constă în principal din hidrocarburi al căror număr de atomi de carbon variază în principal între C6 şi C11, al căror punct de fierbere este cuprins între aproximativ 3°C şi 194°C (37°F şi 382°F).] (ro)
C&L Inventory
[Ogļūdeņražu savienojumu komplekss, kas iegūts, destilējot vieglā destilāta hidrogenēšanas procesa produktus. Sastāv no ogļūdeņražiem ar oglekļa atomu skaitu pārsvarā no C6 līdz C9, aptuvenā viršanas temperatūra no 3°C līdz 194°C (37°F līdz 382°F).] (lv)
C&L Inventory
[Složitá směs uhlovodíků získaná destilací produktů lehkého destilátu z hydrogenace. Je složena z uhlovodíků s počtem uhlíkových atomů převážně v rozmezí C6 až C9 s rozmezím teplot varu přibližně 3 °C až 194 °C.] (cs)
C&L Inventory
[Sudėtinis angliavandenilių mišinys, gaunamas distiliuojant lengvojo distiliato hidrinimo proceso produktus. Jį sudaro angliavandeniliai, turintys anglies atomų skaičių daugiausia nuo C6 iki C9, ir kurių virimo temperatūra maždaug nuo 3 °C iki 194 °C (nuo 37 °F iki 382 °F).] (lt)
C&L Inventory
[Szénhidrogének komplex elegye, melyet a könnyű desztillátum hidrogénes kezeléséből származó termékek desztillációjával nyernek. Olyan szénhidrogénekből áll, melyek szénatomszáma főleg a C6-C9 tartományban van, forráspont tartománya kb. 3°C-tól 194°C-ig (37°F-től 382°F-ig) terjed.] (hu)
C&L Inventory
[Πολύπλοκος συνδυασμός υδρογονανθράκων που λαμβάνεται από την απόσταξη προϊόντων από την υδρογονοκατεργασία ελαφρού αποστάγματος. Συνίσταται από υδρογονάνθρακες με αριθμό ατόμων άνθρακα κυρίως μεταξύ C6 και C9 που αποστάζουν μεταξύ 3 °C και 194 °C περίπου.] (el)
C&L Inventory
[Комплексна комбинация от въглеводороди , получена при дестилация на продукти от процес на обработване на леки дестилати с водород. Състои се от въглеводороди с брой на въглеродните атоми основно в интервала от C6 до C9 включително и с температура на кипене приблизително в интервала от 3°C до 194°C (37°F до 382°F).] (bg)
C&L Inventory
Alacsony forráspontú hidrogénnel kezelt benzin (hu)
C&L Inventory
combinación compleja de hidrocarburos obtenida por la destilación de productos del proceso de tratamiento con hidrógeno del destilado ligero; compuesta de hidrocarburos con un número de carbonos en su mayor parte dentro del intervalo de C6 a C9 y con un intervalo de ebullición aproximado de 3 °C a 194 °C (es)
C&L Inventory
Combinaison complexe d'hydrocarbures obtenue par distillation des produits issus de l'hydrotraitement de distillats légers. Se compose d'hydrocarbures dont le nombre de carbones se situe principalement dans la gamme C6-C9 et dont le point d'ébullition est approximativement compris entre 3°C et 194°C. (fr)
C&L Inventory
Combinazione complessa di idrocarburi ottenuta per distillazione di prodotti provenienti da un processo di hydrotreating di distillati leggeri. È costituita da idrocarburi con numero di atomi di carbonio prevalentemente nell'intervallo C6-9 e punto di ebollizione nell'intervallo 3 °C - 194 °C ca. (da 37°F a 382°F). (it)
C&L Inventory
Combinação complexa de hidrocarbonetos obtida por destilação dos produtos de um processo de tratamento com hidrogénio de um destilado leve. É constituída por hidrocarbonetos com número de átomos de carbono predominantemente na gama C6 a C9 e destilação no intervalo aproximado de 3 °C a 194 °C. (pt)
C&L Inventory
Destilados (petróleo), do tratamento de destilados leves com hidrogénio, de intervalo de destilação baixo (pt)
C&L Inventory
destilados (petróleo), proceso de tratamiento con hidrógeno del destilado ligero, bajo punto de ebullición (es)
C&L Inventory
Destilati (nafta), proces hidroobrade lakog destilata, nisko-vrijući (hr)
C&L Inventory
destilati (zemeljsko olje), lahki destilati iz procesa obdelave z vodikom, nizka temperatura vrelišča (sl)
C&L Inventory
Destillaadid (nafta), kerge destillaadi hüdrogeenimisprotsess, madala keemispunktiga (et)
C&L Inventory
Destillat (petroleum), lätta vätebehandlade, lågkokande (sv)
C&L Inventory
Destillate (Erdöl), leichtes Destillat, Wasserstoffbehandlungsverfahren, niedrigsiedend (de)
C&L Inventory
Destillaten (aardolie), waterstofbehandelde lichte fracties, laagkokend (nl)
C&L Inventory
destillater (petroleum), lett destillat hydrogenbehandlingsprosess, lavtkokende (no)
C&L Inventory
destillater (råolie), let destillat hydrogenbehandlingsproces-, lavtkogende (da)
C&L Inventory
Destiláty (ropné), lehký destilát z hydrogenace, nízkovroucí (cs)
C&L Inventory
destiláty (ropné), z hydrogenácie ľahkej benzínovej frakcie, s nízkou teplotou varu (sk)
C&L Inventory
Destilāti (nafta), vieglie, apstrādāti ar ūdeņradi, virst zemā temperatūrā (lv)
C&L Inventory
Destylaty lekkie obrabiane wodorem (ropa naftowa) (pl)
C&L Inventory
Desztillátumok (nyersolaj), könnyű desztillátum hidrogénes kezelés, alacsony forráspontú (hu)
C&L Inventory
Distilate (petrol), fracţia uşoară din procesul de hidrotratare, punct de fierbere scăzut (mt)
C&L Inventory
Distilate (petrol), fracţia uşoară din procesul de hidrotratare, punct de fierbere scăzut (ro)
C&L Inventory
Distiliatai (nafta), hidrinimo proceso lengvasis distiliatas, žemos virimo temperatūros (lt)
C&L Inventory
distillati (petrolio), processo di hydrotreating di distillati leggeri, bassobollenti (it)
C&L Inventory
Distillats légers hydrotraités (pétrole), à bas point d'ébullition;naphta hydrotraité à bas point d'ébullition;[Combinaison complexe d'hydrocarbures obtenue par distillation des produits résultant de l'hydrotraitement de distillats légers. Se compose d'hydrocarbures comportant majoritairement entre 6 et 9 atomes de carbone (C6-C9) et dont l'intervalle d'ébullition est compris approximativement entre 3 et 194 oC (entre 37 et 382o F).] (fr)
C&L Inventory
Een complexe verzameling koolwaterstoffen, verkregen door destillatie van producten uit de waterstofbehandeling van licht destillaat. Bestaat uit koolwaterstoffen, overwegend C6 tot en met C9, met een kooktraject van ongeveer 3°C tot 194°C. (nl)
C&L Inventory
En sammensat blanding af carbonhydrider opnået ved destillationen af produkter fra hydrogenbehandlingsprocessen af et let destillat. Den består af carbonhydrider, overvejende C6 til og med C9, med kogeinterval omtrent fra 3 °C til 194 °C (37 ºF til 382 ºF). (da)
C&L Inventory
Gehydrogeneerde nafta met laag kookpunt (nl)
C&L Inventory
Hidrogenēts ligroīns ar zemu viršanas temperatūru (lv)
C&L Inventory
hydrogenovaný ťažký benzín s nízkou teplotou varu (sk)
C&L Inventory
Komplex blandning av kolväten erhållen genom destillation av produkterna från en vätebehandling av lätta destillat. Består av kolväten, främst C6 till C9, med ungefärligt kokpunktsintervall från 3 °C till 194 °C. (sv)
C&L Inventory
Lavtkogende hydrogeneret nafta (da)
C&L Inventory
lavtkokende hydrogenbehandlet nafta (no)
C&L Inventory
Lågkokande vätebehandlad nafta (sv)
C&L Inventory
Madala keemispunktiga hüdrogeenitud raskbensiin (et)
C&L Inventory
Matalalla kiehuva vetykäsitelty teollisuusbensiini (fi)
C&L Inventory
Monimutkainen seos hiilivetyjä, saatu tislaamalla tuotteita kevyen tisleen vetykäsittelyprosessista. Koostuu hiilivedyistä, joiden hiililuvut ovat pääasiassa välillä C6:sta C9:ään ja jotka kiehuvat likimäärin välillä 3°C:sta 194°C:een (37°F:sta 382°F:iin). (fi)
C&L Inventory
Nafta cu punct de fierbere scăzut tratată cu hidrogen (mt)
C&L Inventory
Nafta cu punct de fierbere scăzut tratată cu hidrogen (ro)
C&L Inventory
Nafta de baixo ponto de ebulição tratada com hidrogénio (pt)
C&L Inventory
nafta di hydrotreating con basso punto di ebollizione (it)
C&L Inventory
nafta tratada con hidrógeno de bajo punto de ebullición (es)
C&L Inventory
naphta hydrotraité à point d'ébullition bas (fr)
C&L Inventory
Naphtha, wasserstoffbehandelt, niedrigsiedend (de)
C&L Inventory
Nisko-vrijući hidroobrađen benzin (hr)
C&L Inventory
Niskowrząca frakcja naftowa obrabiana wodorem (pl)
C&L Inventory
Nízkovroucí hydrogenovaná benzínová frakce (cs)
C&L Inventory
O combinaţie complexă de hidrocarburi obţinute prin distilarea distilatului uşor de la procesul de hidrotratare. Constă în principal din hidrocarburi al căror număr de atomi de carbon variază în principal între C6 şi C11, al căror punct de fierbere este cuprins între aproximativ 3°C şi 194°C (37°F şi 382°F). (mt)
C&L Inventory
Tisleet (maaöljy), kevyen tisleen vetykäsittelyprosessi, matalalla kiehuvat (fi)
C&L Inventory
z vodikom obdelana nafta z nizko temperaturo vrelišča (sl)
C&L Inventory
Złożona mieszanina węglowodorów otrzymywana podczas destylacji produktów z procesu obróbki lekkiego destylatu wodorem. Składa się z węglowodorów o liczbie atomów węgla głównie w zakresie od C6 do C9, wrzących w zakresie temp. od ok. 3°C do 194°C. (pl)
C&L Inventory
Žematemperatūris hidrintas pirminis benzinas (lt)
C&L Inventory
αποστάγματαΑποστάγματα (πετρελαίου), υδρογονοκατεργασίας ελαφρού αποστάγματος, χαμηλού σημείου ζέσεως (el)
C&L Inventory
Νάφθα χαμηλού σημείου ζέσεως από υδρογονοεπεξεργασία (el)
C&L Inventory
Дестилати (нефт), леки дестилати от процес на обработване с водород, с ниска температура на кипене (bg)
C&L Inventory
Обработен с водород нискооктанов бензин с ниска температура на кипене (bg)
C&L Inventory
Distillates (petroleum), light distillate hydrotreating process, low-boiling
Other
Destiláty (ropné)
C&L Inventory
Distillates (petroleum), light distillate hydrotreating process, low-boiling
C&L Inventory, Registration dossier
Distillates (petroleum), light distillate hydrotreating process, low-boiling
Registration dossier
Distillates (petroleum), light distillate hydrotreating process, low-boiling;
C&L Inventory
Distillates (petroleum)~
C&L Inventory
Distillates(petroleum),light distillate hydrotreating process
C&L Inventory
Distillates (petroleum), light distillate hydrotreating process, low-boiling
Registration dossier
649-332-00-3
Index number
C&L Inventory
68410-97-9
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 2 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [2]
C Form
Other (100%) [2]
C Substance type
Petroleum product (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Melting/freezing point

Study results
  • 3 studies submitted
  • 1 study processed
R Melting / freezing point
-60 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Boiling point

Study results
  • 4 studies submitted
  • 2 studies processed
R Boiling point
-20 - 260 °C @ 101.325 kPa [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Density

Study results
  • 2 studies submitted
  • 2 studies processed
R Relative density
0.62 - 0.88 @ 15 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Vapour pressure

Study results
  • 2 studies submitted
  • 2 studies processed
R Vapour pressure
240 kPa @ 37.8 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Partition coefficient

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Water solubility

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 2 studies submitted
  • 2 studies processed
R Flash point
-40 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 8 studies submitted
  • 3 studies processed
R Autoflammability / self-ignition
280 - 470 °C @ 101.3 - 101.325 kPa [3]

Type of Study provided
Studies with data
Key study 2 1
Supporting study 4 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 2 studies submitted
  • 2 studies processed
C Interpretation of results
Extremely flammable (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Flammability
Extremely flammable (100%)

Explosiveness

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 4 studies submitted
  • 2 studies processed
R kinematic viscosity (in mm²/s)
1 [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water - screening tests

Study results
  • 14 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 12
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Adsorption/desorption

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Study results
  • 1 study submitted
  • 1 study processed
% Distribution in Media:
R Air 93.02 % [1]
R Water 5.83 % [1]
R Soil 0.34 % [1]
R Sediment 0.81 % [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 2 summaries submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No data available: testing technically not feasible (1)
Intermittent releases (freshwater) No data available: testing technically not feasible (1)
Marine water No data available: testing technically not feasible (1)
Intermittent releases (marine water) No data available: testing technically not feasible (1)
Sewage treatment plant (STP) No data available: testing technically not feasible (1)
Sediment (freshwater) No data available: testing technically not feasible (1)
Sediment (marine water) No data available: testing technically not feasible (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil No data available: testing technically not feasible (1)
Hazard for Predators
Secondary poisoning Insufficient hazard data available (further information necessary) (1)

Short–term toxicity to fish

Study results
  • 32 studies submitted
  • 4 studies processed
P/RResults
LL50 (4 days) 8.2 - 10 mg/L [4]

Type of Study provided
Studies with data
Key study 4
Supporting study 28
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 4 studies submitted
  • 2 studies processed
P/RResults
EL50 (21 days) 10 mg/L [2]
NOELR (21 days) 2.6 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 24 studies submitted
  • 2 studies processed
P/RResults
EL50 (48 h) 4.5 mg/L [2]
NOELR (48 h) 500 µg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 22
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 6 studies submitted
  • 2 studies processed
P/RResults
NOELR (21 days) 2.6 - 16 mg/L [4]
EL50 (21 days) 10 - 40 mg/L [4]

Type of Study provided
Studies with data
Key study 2
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 32 studies submitted
  • 2 studies processed
P/RResults
EL50 (4 days) 3.7 mg/L [2]
EL50 (72 h) 3.1 mg/L [2]
NOELR (72 h) 500 µg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 30
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC50 (40 h) 15.41 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 3 summaries submitted
  • 2 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 1.9 mg/m³ repeated dose toxicity
Acute /short term: (DNEL) 1 286.4 mg/m³ neurotoxicity
Local Effects
Long-term: (DNEL) 837.5 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 1 066.67 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: High hazard (no threshold derived)
Acute /short term: High hazard (no threshold derived)
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 410 µg/m³ repeated dose toxicity
Acute /short term: (DNEL) 1 152 mg/m³ neurotoxicity
Local Effects
Long-term: (DNEL) 178.57 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 640 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: High hazard (no threshold derived)
Acute /short term: High hazard (no threshold derived)
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 87 studies submitted
  • 2 studies processed
P/RResults
LD50 5 000 mg/kg bw (rat) [2]
M/CInterpretations of results
Not classified [2]

Type of Study provided
oral
Studies with data
Key study 1 1
Supporting study 45 40
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 79 studies submitted
  • 4 studies processed
M/CInterpretations of results
Not classified [4]

inhalation
Studies with data
Key study 3 1
Supporting study 36 39
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 89 studies submitted
  • 2 studies processed
P/RResults
LD50 2 000 mg/kg bw (rabbit) [2]
M/CInterpretations of results
Not classified [2]

dermal
Studies with data
Key study 1 1
Supporting study 44 43
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Oral route:
No adverse effect observed LD50 5 000 mg/kg bw
Inhalation route:
No adverse effect observed LC50 5.61 mg/L air
Dermal route:
No adverse effect observed LD50 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 209 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1 1
Supporting study 116 90
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 90 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1 1
Supporting study 44 43
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Skin
Adverse effect observed (irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 86 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1 1
Supporting study 42 41
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 10 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Study data: oral
Studies with data
Key study 1
Supporting study 5 4
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 44 studies submitted
  • 4 studies processed
P/RResults
NOAEC (rat): 9.84 - 20 mg/L air [3]
NOAEC (other:): 1.402 mg/L air [2]

Study data: inhalation
Studies with data
Key study 3 1
Supporting study 19 21
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 102 studies submitted
  • 8 studies processed
P/RResults
NOAEL (rat): 375 - 3 750 mg/kg bw/day [2]
NOEL (rabbit): 200 - 2 000 mg/kg bw/day [14]

Study data: dermal
Studies with data
Key study 9 1
Supporting study 43 49
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Inhalation route - systemic effects:
No adverse effect observed NOAEC 1 402 mg/m³ (chronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 43 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 2 3
Supporting study 19 18
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: in vivo
  • 28 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 2 1
Supporting study 12 13
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Toxicity - InVivo
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 24 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1 2
Supporting study 12 9
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Inhalation route:
No adverse effect observed NOAEC 9 869 mg/m³ (chronic, rat)

Toxicity to reproduction

Study results
Study data: reproduction
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 2 1
Supporting study 2 3
Weight of evidence
Other
Data waiving
no waivers
Study data: developmental
  • 17 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 1 2
Supporting study 7 6
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Effect on fertility
Inhalation route:
No adverse effect observed NOAEC 20 000 mg/m³ (chronic, rat)
Effect on developmental toxicity
Dermal route:
No adverse effect observed NOAEL 500 mg/kg bw/day (subchronic, rat)
Inhalation route:
No adverse effect observed NOAEC 23 900 mg/m³ (subchronic, rat)

Neurotoxicity

Study results
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study 2 3
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 1 3
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter mammalian screening - in vivo

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