Brief Profile

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

No image available
EC / List no.:
270-658-3
CAS no.:
68475-70-7
Index number:
649-321-00-3
Molecular formula:
SMILES:
InChI:
Type of substance:
UVCB
Origin:
Petroleum product
Registered compositions:
20
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP01) approved by the European Union, this substance may be fatal if swallowed and enters airways, may cause genetic defects and may cause cancer.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance causes damage to organs through prolonged or repeated exposure, is very toxic to aquatic life with long lasting effects, is toxic in contact with skin, is toxic if inhaled, is toxic if swallowed, is very toxic to aquatic life, is suspected of damaging fertility or the unborn child, causes serious eye irritation, is a highly flammable liquid and vapour, may cause respiratory irritation, causes skin irritation, may cause an allergic skin reaction and may cause drowsiness or dizziness.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance is toxic to aquatic life with long lasting effects.

Breakdown of all 199 C&L notifications submitted to ECHA

Aquatic Chronic 2 H411
Asp. Tox. 1 H304 Harmonised Classification
Muta. 1B H340 Harmonised Classification
Flam. Liq. 2 H225
Carc. 1B H350 Harmonised Classification
Repr. 2 H361
Eye Irrit. 2 H319
STOT RE 1 H372
Acute Tox. 4 H312
STOT RE 2 H373
STOT SE 3 H335
Acute Tox. 3 H331
Carc. 1A H350
Aquatic Acute 1 H400
Aquatic Chronic 1 H410
https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/more.png 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • C
Officially recognised in the EU as Carcinogenic (Harmonised C&L).
  • C
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Carcinogenic (25% of REACH registrations).
  • M
Officially recognised in the EU as Mutagenic (Harmonised C&L).
  • M
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Mutagenic (25% of REACH registrations).
  • Ss
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Skin sensitising (25% of REACH registrations).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 14 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 000 to < 10 000 000 tonnes per annum.

This substance is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: fuels.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the types of manufacture using this substance.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and in materials as fuel sources, with limited exposure to unburned product to be expected.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, transfer of substance into small containers and batch processing in synthesis or formulation with opportunity for exposure.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, manufacturing of the substance, formulation in materials, in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture, as processing aid and of substances in closed systems with minimal release.

This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and batch processing in synthesis or formulation with opportunity for exposure.

Release to the environment of this substance can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), of substances in closed systems with minimal release, in processing aids at industrial sites, manufacturing of the substance and as processing aid.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure, transfer of substance into small containers, laboratory work and closed batch processing in synthesis or formulation.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance and in processing aids at industrial sites.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: obtain special instructions before use; keep away from heat, sparks, open flames and/or hot surfaces – No smoking; wash parts of the body (as specified by manufacturer/supplier)in contact with substance thoroughly after handling; avoid release to the environment; do not handle until all safety precautions have been read and understood; do not breathe the dust, fume, gas, mist, vapours or spray; contaminated work clothing should not be allowed out of the workplace; avoid breathing the dust, fume, gas, mist, vapours or spray; take actions to prevent static discharges; do not eat, drink or smoke when using this product; use only outdoors or in a well-ventilated area; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If swallowed: call a poison center or doctor/physician if you feel unwell. If swallowed: immediately call a poison center or doctor/physician. If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. If eye irritation persists get medical advice/attention. Get medical advice/attention if you feel unwell. Do not induce vomiting. If swallowed: rinse mouth. Do not induce vomiting. Wash contaminated clothing before reuse. If inhaled: remove victim to fresh air and keep at rest in a position comfortable for breathing. If exposed or concerned: get medical advice/attention. Collect spillage. Follow specific treatment (see label). Rinse the mouth. If inhaled: call a poison center or doctor/physician if you feel unwell. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.

Storage statements

Store this substance in a dry place; locked up; in a well-ventilated place and keeping container tightly closed.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • BD&I_37, rue Omer Lepreux, 92 1081 bruxelles Belgium Belgium
  • DEZA a.s., Masarykova 753 75701 Valasske Mezirici Czech Republic
  • LUKOIL Neftohim Burgas AD (Stavrolen), Western Industrial Zone 8104 Bourgas Bulgaria
  • MOL Petrochemicals Private Company Limited by Shares, TVK-Ipartelep, TVK Központi Irodaház (136. sz. épület, hrsz: 2119/3) 3581 Tiszaujvaros Hungary
  • Naphtachimie SA, Place de la Coupole, 2 La Défence 6 92400 Courbevoie France
  • OMV Deutschland Operations GmbH & Co.KG, Haiminger Straße 1 D-84489 Burghausen Germany
  • Raffinerie Heide GmbH, Meldorfer Straße 43 25770 Hemmingstedt Germany
  • Repsol Petroleo, S.A., Calle Mendez Alvaro, 44 28045 Madrid Madrid Spain
  • Ruhr Oel GmbH, Pawiker Strasse 30 45896 Gelsenkirchen Germany
  • Shell Deutschland GmbH, Suhrenkamp 71-77, 22335 Hamburg Germany
  • TotalEnergies Olefins Antwerp, Scheldelaan 10 2030 Antwerpen Belgium
  • TotalEnergies Petrochemicals France SA, Immeuble Le Linéa 1, rue du Général Leclerc 92047 Paris La Défence Cedex France
  • TotalEnergies Raffinage France, 2, place Jean Millier, La Défense 92400 Courbevoie France
  • TotalEnergies Refinery Antwerp, SCHELDELAAN 16, 2030 Antwerpen Belgium
  • LUKOIL Neftohim Burgas AD (KNH), Western Industrial Zone 8104 Bourgas Bulgaria

Substance names and other identifiers

[A complex combination of hydrocarbons obtained by the fractionation pyrolysis at 816°C (1500°F) of naphtha and raffinate. It consists predominantly of aromatic hydrocarbons having carbon numbers predominantly in the range of C6 through C8, including benzene.]
A complex combination of hydrocarbons obtained by the fractionation pyrolysis at 816°C (1500°F) of naphtha and raffinate. It consists predominantly of aromatic hydrocarbons having carbon numbers predominantly in the range of C6 through C8, including benzene.
C&L Inventory
Aromatic concentrate (BTX)
A complex combination of hydrocarbons obtained by the fractionation pyrolysis at 816°C (1500°F) of naphtha and raffinate. It consists predominantly of aromatic hydrocarbons having carbon numbers predominantly in the range of C6 through C8, including benzene.
Other
Aromatic hydrocarbons, C6-8, naphtha-raffinate pyrolyzate-derived
EC Inventory, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances
Aromatic hydrocarbons, C6-8, naphtha-raffinate pyrolyzate-derived
A complex combination of hydrocarbons obtained by the fractionation pyrolysis at 816°C (1500°F) of naphtha and raffinate. It consists predominantly of aromatic hydrocarbons having carbon numbers predominantly in the range of C6 through C8, including benzene.
C&L Inventory, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances
Aromatic hydrocarbons, C6-8, naphtha-raffinate pyrolyzate-derived; Low boiling point thermally cracked naphtha [ complex combination of hydrocarbons obtained by the fractionation pyrolysis at 816 o C (1 500 °F) of naphtha and raffinate. It consists predominantly of aromatic hydrocarbons having carbon numbers predominantly in the range of C6 through C8, including benzene.]
A complex combination of hydrocarbons obtained by the fractionation pyrolysis at 816°C (1500°F) of naphtha and raffinate. It consists predominantly of aromatic hydrocarbons having carbon numbers predominantly in the range of C6 through C8, including benzene.
Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances
Aromatic hydrocarbons, C6-8, naphtha-raffinate pyrolyzate-derived; Low boiling point thermally cracked naphtha [A complex combination of hydrocarbons obtained by the fractionation pyrolysis at 816 o C (1 500 °F) of naphtha and raffinate. It consists predominantly of aromatic hydrocarbons having carbon numbers predominantly in the range of C6 through C8, including benzene.]
A complex combination of hydrocarbons obtained by the fractionation pyrolysis at 816°C (1500°F) of naphtha and raffinate. It consists predominantly of aromatic hydrocarbons having carbon numbers predominantly in the range of C6 through C8, including benzene.
Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work
Low boiling point thermally cracked naphtha
A complex combination of hydrocarbons obtained by the fractionation pyrolysis at 816°C (1500°F) of naphtha and raffinate. It consists predominantly of aromatic hydrocarbons having carbon numbers predominantly in the range of C6 through C8, including benzene.
C&L Inventory
(Keerulise koostisega süsivesinike segu, mis saadakse raskbensiini ja rafinaadi pürolüütilisel fraktsioonimisel 816 ° C juures. Koosneb valdavalt aromaatsetest süsivesinikest, mille süsiniku aatomite arv on peamiselt vahemikus C6 kuni C8, kaasa arvatud benseen.] (et)
C&L Inventory
(Složeni sastav ugljikovodika dobiven frakcijskom pirolizom benzina i rafinata na 816 °C. Sastoji se pretežito od aromatskih ugljikovodika koji imaju broj ugljikovih atoma pretežito u području od C6 do C8, uključujući benzen.) (hr)
C&L Inventory
[(Složitá směs uhlovodíků získaná pyrolýzní frakcionací benzínu a rafinátu při 816 °C. Je složena převážně z aromatických uhlovodíků s počtem uhlíkových atomů převážně v rozmezí C6 až C8 , včetně benzenu.] (cs)
C&L Inventory
[Kompleks blanding av hydrokarboner dannet ved pyrolysefraksjonering ved 816 °C (1500 °F) av nafta og raffinat. Består for det meste av aromatiske hydrokarboner, hovedsakelig C6 til C8, inklusive benzen.] (no)
C&L Inventory
[Kompleksna kombinacija ogljikovodikov dobljena s frakcionirno pirolizo nafte in rafinata pri 816 °C. Sestoji pretežno iz aromatskih ogljikovodikov s številom ogljikovih atomov pretežno v območju med C6 in C8, vključno z benzenom.] (sl)
C&L Inventory
[komplexe Kombination von Kohlenwasserstoffen, erhalten durch pyrolytische Zersetzung von Naphtha und Raffinat bei 816 °C; besteht vorwiegend aus aromatischen Kohlenwasserstoffen mit Kohlenstoffzahlen überwiegend im Bereich von C6 bis C8, einschließlich Benzol] (de)
C&L Inventory
[Komplexná zmes uhľovodíkov získavaná frakcionačnou pyrolýzou ťažkého benzínu a rafinátu pri 816 °C. Pozostáva predovšetkým z aromatických uhľovodíkov s počtom atómov uhlíka prevažne v rozmedzí od C6 do C8, vrátane benzénu.] (sk)
C&L Inventory
[O combinaţie complexă de hidrocarburi obţinută prin fracţionarea prin piroliză la 816°C (1500°F) a ţiţeiului şi produselor rafinate. Constă în principal din hidrocarburi al căror număr de atomi de carbon variază în principal între C6 şi C8, inclusiv benzen.] (ro)
C&L Inventory
[Ogļūdeņražu savienojumu komplekss, kas iegūts ligroīna un rafinātu pirolīzes frakcionēšanā 816°C (1500°F) temperatūrā. Sastāv pārsvarā no aromātiskiem ogļūdeņražiem galvenokārt ar oglekļa atomu skaitu C6 līdz C8, ieskaitot benzolu.] (lv)
C&L Inventory
[Sudėtinis angliavandenilių mišinys, gaunamas vykdant pirminio benzino ir rafinato pirolizinį frakcionavimą esant 816 °C (1500 °F). Jį sudaro daugiausia aromatiniai angliavandeniliai, turintys anglies atomų skaičių daugiausia nuo C6 iki C8, įskaitant benzeną.] (lt)
C&L Inventory
[Szénhidrogének komplex elegye, melyet benzin és raffinátum 816°C-on (1500°F-en) végzett frakcionált pirolízisével nyernek. Főleg aromás szénhidrogénekből áll (beleértve a benzolt is), melyek szénatomszáma főleg a C6-C8 tartományban van.] (hu)
C&L Inventory
[Πολύπλοκος συνδυασμός υδρογονανθράκων που λαμβάνεται από την πυρολυτική κλασμάτωση νάφθας και εξευγενισμένου προϊόντος στους 816 °C. Συνίσταται κυρίως από αρωματικούς υδρογονάνθρακες με αριθμό ατόμων άνθρακα κυρίως μεταξύ C6 και C8, μεταξύ των οποίων βενζόλιο.] (el)
C&L Inventory
[Комплексна комбинация от въглеводороди, получени от пиролизно фракциониране при 816°C (1500°F) на нискооктанов бензин и рафинат.Състои се основно от ароматни въглеводороди с брой на въглеродните атоми преобладаващо в интервала от C6 до C8 включително, включваща бензен.] (bg)
C&L Inventory
Alacsony forráspontú termikusan krakkolt benzin (hu)
C&L Inventory
Aromaatsed süsivesinikud, C6–8, pürolüsaadist saadud bensiinifraktsiooni rafinaat (et)
C&L Inventory
Aromaattiset hiilivedyt, C6-8, teollisuusbensiinijaloste pyrolysaattijohdettu (fi)
C&L Inventory
aromatické C6-8-uhľovodíky, z pyrolýzy benzínového rafinátu (sk)
C&L Inventory
Aromatické uhlovodíky, C6-8, pyrolyzát benzínu a rafinátu (cs)
C&L Inventory
Aromatiniai angliavandeniliai, C6-8, pirminio benzino ir rafinato pirolizės (lt)
C&L Inventory
Aromatische Kohlenwasserstoffe, C6-8, pyrolysiertes Naphtha und Raffinat (de)
C&L Inventory
Aromatische koolwaterstoffen, C6-8-, afkomstig van pyrolysaat van nafta-raffinaat (nl)
C&L Inventory
Aromatiska kolväten, C6-8-, nafta- och raffinatpyrolysatutvunna (sv)
C&L Inventory
aromatiske carbonhydrider, C6-8-, naphtha- og raffinatpyrolysatafledte (da)
C&L Inventory
aromatiske hydrokarboner, C6-8, fremstilt ved pyrolyse av nafta og raffinat (no)
C&L Inventory
aromatski ogljikovodiki, C6-8, derivati pirolizata nafte in rafinata (sl)
C&L Inventory
Aromatski ugljikovodici, C6-8, dobiveni iz piroliziranog rafinata benzina (hr)
C&L Inventory
Aromás szénhidrogének, C6-8, benzin raffinátum pirolizátum származék (hu)
C&L Inventory
Aromātiskie ogļūdeņraži, C6-8, pirolīzē iegūts ligroīna rafināts (lv)
C&L Inventory
combinación compleja de hidrocarburos obtenida por fraccionamiento por pirólisis a 816 °C de nafta y refino; compuesta principalmente de hidrocarburos aromáticos con un número de carbonos en su mayor parte dentro del intervalo de C6 a C8, incluyendo benceno (es)
C&L Inventory
Combinaison complexe d'hydrocarbures obtenue par fractionnement par pyrolyse à 816°C de naphta et de raffinat. Se compose principalement d'hydrocarbures aromatiques dont le nombre de carbones se situe en majorité dans la gamme C6-C8, et notamment de benzène. (fr)
C&L Inventory
Combinazione complessa di idrocarburi ottenuta dal frazionamento per pirolisi a 816 °C (1500° F) di nafta e raffinato. È costituita in prevalenza da idrocarburi aromatici con numero di atomi di carbonio prevalentemente nell'intervallo C6-8, comprendenti anche benzene. (it)
C&L Inventory
Combinação complexa de hidrocarbonetos proveniente do fraccionamento por pirólise a 816 °C de nafta e refinado. É constituída predominantemente por hidrocarbonetos aromáticos com número de átomos de carbono predominantemente na gama C6 a C8, incluindo benzeno. (pt)
C&L Inventory
Een complexe verzameling koolwaterstoffen, verkregen door pyrolysefractionering bij 816°C van nafta en raffinaat. Bestaat voornamelijk uit aromatische koolwaterstoffen, overwegend C6 tot en met C8, inclusief benzeen. (nl)
C&L Inventory
En sammensat blanding af carbonhydrider opnået ved fraktioneringspyrolyse ved 816 °C (1500 ºF) af naphtha og raffinat. Den består overvejende af aromatiske carbonhydrider, overvejende C6 til og med C8, herunder benzen. (da)
C&L Inventory
Fracţia nafta cu punct de fierbere la temperaturi scăzute, cracată termic (mt)
C&L Inventory
Fracţia nafta cu punct de fierbere la temperaturi scăzute, cracată termic (ro)
C&L Inventory
Hidrocarbonetos aromáticos, C6-8, derivados do pirolisado de nafta e refinado (pt)
C&L Inventory
Hidrocarburi aromatice, C6-8, derivate ale fracţiei nafta - rafinate prin piroliză (mt)
C&L Inventory
Hidrocarburi aromatice, C6-8, derivate ale fracţiei nafta - rafinate prin piroliză (ro)
C&L Inventory
hidrocarburos aromáticos, C6-8, derivados del pirolizado de nafta y refino (es)
C&L Inventory
hydrocarbures aromatiques en C6-8, dérivés de pyrolysat de naphta et de raffinat; naphta de craquage thermique à bas point d'ébullition; [combinaison complexe d'hydrocarbures obtenue par fractionnement par pyrolyse à 816 oC (1500 oF) de naphta et de raffinat. Se compose principalement d'hydrocarbures aromatiques comportant majoritairement entre 6 et 8 atomes de carbone (C6-C8), y compris de benzène.] (fr)
C&L Inventory
idrocarburi aromatici, C6-8, derivati da pirolisi di raffinato e nafta (it)
C&L Inventory
Komplex blandning av kolväten erhållen genom pyrolysfraktionering vid 816 °C av nafta och raffinat. Består främst av aromatiska kolväten, i synnerhet C6 till C8, bl.a. bensen. (sv)
C&L Inventory
Lavtkogende termisk krakket nafta (da)
C&L Inventory
lavtkokende termisk krakket nafta (no)
C&L Inventory
Lågkokande termiskt krackad nafta (sv)
C&L Inventory
Madala keemispunktiga termiliselt krakitud raskbensiin (et)
C&L Inventory
Matalalla kiehuva lämpökrakattu teollisuusbensiini (fi)
C&L Inventory
Monimutkainen seos hiilivetyjä, saatu teollisuusbensiinin ja jalosteen pyrolyysijakotislauksella 816°C:ssa (1500°F). Koostuu pääasiassa aromaattisista hiilivedyistä, joiden hiililuvut ovat pääasiassa välillä C6:sta C8:aan, mukaan lukien bentseeni. (fi)
C&L Inventory
nafta craqueada térmicamente de bajo punto de ebullición (es)
C&L Inventory
Nafta de baixo ponto de ebulição de cracking térmico (pt)
C&L Inventory
nafta di cracking termico con basso punto di ebollizione (it)
C&L Inventory
naphta de craquage thermique à point d'ébullition bas (fr)
C&L Inventory
Naphtha, thermisch gekrackt, niedrigsiedend (de)
C&L Inventory
Nisko-vrijući termički krekiran benzin (hr)
C&L Inventory
Niskowrząca benzyna z krakingu termicznego (pl)
C&L Inventory
Nízkovroucí tepelně krakovaná benzínová frakce (cs)
C&L Inventory
O combinaţie complexă de hidrocarburi obţinută prin fracţionarea prin piroliză la 816°C (1500°F) a ţiţeiului şi produselor rafinate. Constă în principal din hidrocarburi al căror număr de atomi de carbon variază în principal între C6 şi C8, inclusiv benzen. (mt)
C&L Inventory
tepelne krakovaný ťažký benzín s nízkou teplotou varu (sk)
C&L Inventory
Termiskā krekinga ligroīns ar zemu viršanas temperatūru (lv)
C&L Inventory
termokrekirana nafta z nizko temperaturo vrelišča (sl)
C&L Inventory
Thermisch gekraakte nafta met laag kookpunt (nl)
C&L Inventory
Węglowodory aromatyczne C6-8, rafinowana benzyna z pirolizy (pl)
C&L Inventory
Złożona mieszanina węglowodorów otrzymywana przez pirolityczne frakcjonowanie w temp. 816°C benzyny ciężkiej i rafinatu. Składa się przede wszystkim z węglowodorów aromatycznych o liczbie atomów węgla głównie w zakresie od C6 do C8, w tym benzenu. (pl)
C&L Inventory
Žematemperatūris terminio krekingo pirminis benzinas (lt)
C&L Inventory
αρωματικοί υδρογονάνθρακες, C6-8, από προϊόν πυρόλυσης νάφθας και εξευγενισμένου προίόντος (el)
C&L Inventory
Νάφθα χαμηλού σημείου ζέσεως από θερμική πυρόλυση (el)
C&L Inventory
Ароматни въглеводороди, C6-8, получени от пиролизат на нискооктанов бензин-рафинат (bg)
C&L Inventory
Нискооктанов бензин от термичен крекинг с ниска температура на кипене (bg)
C&L Inventory
Aromatic hydrocarbons, C6-8, naphtha-raffinate pyrolyzate-derived
Other
Aromatic hydrocarbons C6-8
Registration dossier
Aromatic hydrocarbons, C6-8, naphta-raffinate, pyrolyzate-derived
Registration dossier
aromatic hydrocarbons, C6-8, naphtha-raffinate pyrolyzate derived
Registration dossier
aromatic hydrocarbons, C6-8, naphtha-raffinate pyrolyzate derived
Registration dossier
Aromatic hydrocarbons, C6-8, naphtha-raffinate pyrolyzate-derived
C&L Inventory, Registration dossier
Aromatic hydrocarbons, C6-8, naphtha-raffinate pyrolyzate-derived
Registration dossier
Benzolreicher Aromatenschnitt
Registration dossier
Essence brute
Registration dossier
Essence totale de vapocraquage
Registration dossier
Gasoline BO6/BO7 NC GEXARO
Registration dossier
Pygas heartcut
Registration dossier
Pyrogasoline
Registration dossier
raw gasoline
Registration dossier
649-321-00-3
Index number
C&L Inventory
68475-70-7
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 24 studies submitted
  • 23 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [23]
C Form
Other (89%), Viscous (11%) [9]
C Odour
Characteristic of aromatic compounds (76%), Other (19%) [21]
C Substance type
Petroleum product (62%), Organic (38%) [21]

Type of Study provided
Studies with data
Key study 6 17
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 7 studies submitted
  • 6 studies processed
R Melting / freezing point
-100 - -29 °C @ 101.3 kPa [8]

Type of Study provided
Studies with data
Key study 6
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
-66.9 °C

Boiling point

Study results
  • 21 studies submitted
  • 13 studies processed
R Boiling point
54.3 - 260 °C @ 100.7 - 101.33 kPa [15]

Type of Study provided
Studies with data
Key study 9 5
Supporting study 1 6
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
142 °C

Density

Study results
  • 13 studies submitted
  • 5 studies processed
R Relative density
0.83 - 0.89 @ 20 °C [5]

Type of Study provided
Studies with data
Key study 6
Supporting study 1 6
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
0.87

Vapour pressure

Study results
  • 29 studies submitted
  • 21 studies processed
R Vapour pressure
4 - 550 hPa @ 20 - 50 °C [29]

Type of Study provided
Studies with data
Key study 21
Supporting study 3 5
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
11.14 kPa @ 20 °C

Partition coefficient

Study results
  • 9 studies submitted
  • 7 studies processed
R Log Pow
2.2 - 6.5 @ -248.15 - 25 °C and pH 6.2 - 7 [7]

Type of Study provided
Studies with data
Key study 7
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
5.84 @ 20 °C

Water solubility

Study results
  • 6 studies submitted
  • 6 studies processed
R Water solubility (mass/vol.)
25 - 600 mg/L @ 20 °C and pH 5.2 - 9.1 [5]
R Water solubility (vol%)
0.1 - 0.7 vol% @ 20 °C and pH 6.4 [2]

Type of Study provided
Studies with data
Key study 6
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
290 mg/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 6 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 6
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Surface tension at 20 °C
71.1 mN/m @ 243 mg/L

Flash point

Study results
  • 7 studies submitted
  • 7 studies processed
R Flash point
-30 - 43 °C @ 101.3 kPa [9]

Type of Study provided
Studies with data
Key study 7
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
7.4 °C

Auto flammability

Study results
  • 6 studies submitted
  • 6 studies processed
R Autoflammability / self-ignition
401 - 502 °C @ 101.3 kPa [6]

Type of Study provided
Studies with data
Key study 6
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
429 °C

Flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Viscosity

Study results
  • 7 studies submitted
  • 6 studies processed
R dynamic viscosity (in mPa s)
0.45 - 0.95 [10]
R kinematic viscosity (in mm²/s)
0.54 - 1.5 [13]

Type of Study provided
Studies with data
Key study 6
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Dynamic viscosity at 20 °C
0.723 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Under test conditions no biodegradation observed (100%)

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation Factor (BCF) - dimensionless
1 112

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No data available: testing technically not feasible (1)
Intermittent releases (freshwater) No data available: testing technically not feasible (1)
Marine water No data available: testing technically not feasible (1)
Intermittent releases (marine water) No data available: testing technically not feasible (1)
Sewage treatment plant (STP) No data available: testing technically not feasible (1)
Sediment (freshwater) No data available: testing technically not feasible (1)
Sediment (marine water) No data available: testing technically not feasible (1)
Hazard for Air
Air Hazard related to composition of atmosphere identified (1)
Hazard for Terrestrial Organism
Soil No data available: testing technically not feasible (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
LC50 (4 days) 1 mg/L [1]
LL50 (4 days) 1.1 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Short–term toxicity to aquatic invertebrates

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC50 (48 h) 1.2 - 2.7 mg/L [2]
EL50 (48 h) 1.2 - 3.3 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to aquatic algae and cyanobacteria

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC50 (4 days) 910 - 1 800 µg/L [4]
EC50 (72 h) 1.3 - 2 mg/L [2]
NOEC (4 days) 120 µg/L [1]
EL50 (4 days) 1.2 - 2.2 mg/L [4]
EL50 (72 h) 1.5 - 2.3 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 3.25 mg/m³ carcinogenicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 23.4 mg/kg bw/day carcinogenicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: Low hazard (no threshold derived)
EYE Exposure
Low hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DMEL) 3.25 µg/m³ carcinogenicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DMEL) 464 ng/kg bw/day carcinogenicity
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 17 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 5 1
Supporting study 6 2
Weight of evidence
Other 2
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: dermal absorption
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study 1
Supporting study 3 3
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation potential:
Low bioaccumulation potential
Absorption values
Oral: 100 %
Dermal: 1 %
Inhalation: 50 %

Acute toxicity

Study results
oral
  • 8 studies submitted
  • 8 studies processed
P/RResults
LD50 512 - 6 631 mg/kg bw (rat) [10]
LD50 5 251 - 5 627 mg/kg bw (mouse) [2]
M/CInterpretations of results
Practically nontoxic [1]

Type of Study provided
oral
Studies with data
Key study 8
Supporting study
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 9 studies submitted
  • 9 studies processed
P/RResults
LC50 (6 h) 1.723 mg/L air (rat) [1]
LC50 (6 h) 284 - 353 ppm (rat) [2]
LC50 (4 h) 5.14 - 43.767 mg/L air (rat) [6]
LC50 (4 h) 5 922 - 13 700 ppm (rat) [6]
LC50 (6 h) 738.5 mg/m³ air (mouse) [1]
M/CInterpretations of results
Toxic [2]

inhalation
Studies with data
Key study 8 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 7 studies submitted
  • 7 studies processed
P/RResults
LD50 2 000 mg/kg bw (rat) [1]
LD50 2 000 - 12 126 mg/kg bw (rabbit) [4]
LD50 5 000 mL/kg bw (rabbit) [1]
M/CInterpretations of results
Practically nontoxic [2]

dermal
Studies with data
Key study 6
Supporting study
Weight of evidence 1
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed LD50 5 000 mg/kg bw
Inhalation route:
No adverse effect observed LC50 20 mg/L air
Dermal route:
No adverse effect observed LD50 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2 5
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: eye
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 3 1
Supporting study
Weight of evidence 3
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
Adverse effect observed (irritating)
Eye
Adverse effect observed (irritating)
Respiratory
No adverse effect observed (not irritating)

Sensitisation

Study results
Study data: skin
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 4
Supporting study
Weight of evidence 1
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 12 studies submitted
  • 8 studies processed
P/RResults
NOAEL (rat): 4 - 625 mg/kg bw/day [9]
NOAEL (mouse): 625 mg/kg bw/day [1]
LOAEL (rat): 25 - 1 250 mg/kg bw/day [4]
LOAEL (mouse): 1 250 mg/kg bw/day [1]

Type of Study provided
Study data: oral
Studies with data
Key study 6 2
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Study data: inhalation
  • 15 studies submitted
  • 13 studies processed
P/RResults
NOAEC (rat): 96 - 2 355 mg/m³ air [3]
NOAEC (rat): 30 - 7 000 ppm [12]
NOAEC (mouse): 32 - 96 mg/m³ air [2]
NOAEC (mouse): 5 - 2 000 ppm [5]
LOAEC (rat): 2.261 - 4.71 mg/L air [2]

Study data: inhalation
Studies with data
Key study 11 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Study data: dermal
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route - systemic effects:
Adverse effect observed LOAEL 25 mg/kg bw/day (subchronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 24 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 18 4
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: in vivo
  • 13 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 4 7
Supporting study 1
Weight of evidence
Other 1
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Toxicity - InVivo
Adverse effect observed (positive)

Carcinogenicity

Study results
  • 12 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 7 5
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
Adverse effect observed LOAEL 25 mg/kg bw/day (chronic, rat)
Inhalation route:
Adverse effect observed LOAEC 960 mg/m³ (chronic, mouse)

Toxicity to reproduction

Study results
Study data: reproduction
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 6 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: developmental
  • 16 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 11 3
Supporting study
Weight of evidence 1
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Study results
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 4 4
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant