Brief Profile

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
270-993-5
CAS no.:
68513-03-1
Index number:
649-304-00-0
Molecular formula:
SMILES:
InChI:
Type of substance:
UVCB
Origin:
Petroleum product
Registered compositions:
5
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP01) approved by the European Union, this substance may be fatal if swallowed and enters airways, may cause genetic defects and may cause cancer.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is toxic to aquatic life with long lasting effects, is an extremely flammable liquid and vapour, is suspected of damaging fertility or the unborn child, causes skin irritation and may cause drowsiness or dizziness.

Breakdown of all 28 C&L notifications submitted to ECHA

Asp. Tox. 1 H304 Harmonised Classification
Muta. 1B H340 Harmonised Classification
Carc. 1B H350 Harmonised Classification
Aquatic Chronic 2 H411
Skin Irrit. 2 H315
STOT SE 3 H336
Repr. 2 H361
Flam. Liq. 2 H225
Flam. Liq. 1 H224
Flam. Liq. 3 H226
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • C
Officially recognised in the EU as Carcinogenic (Harmonised C&L).
  • C
There is broad agreement in that a majority of data submitters agree this substance is Carcinogenic (76% of REACH registrations).
  • M
Officially recognised in the EU as Mutagenic (Harmonised C&L).
  • M
There is broad agreement in that a majority of data submitters agree this substance is Mutagenic (76% of REACH registrations).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 3 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 000 to < 1 000 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: fuels, air care products, anti-freeze products, coating products, lubricants and greases, washing & cleaning products and welding & soldering products.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids), indoor use as processing aid and outdoor use as processing aid.

This substance is used in the following activities or processes at workplace: production of mixtures or articles by tabletting, compression, extrusion or pelletisation and the low energy manipulation of substances bound in materials or articles.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, manufacturing of the substance, formulation of mixtures, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid and of substances in closed systems with minimal release.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the types of manufacture using this substance.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure and closed batch processing in synthesis or formulation.

Other release to the environment of this substance is likely to occur from: indoor use as processing aid, outdoor use as processing aid, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and laboratory work.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, manufacturing of the substance, formulation in materials, in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture, as processing aid and of substances in closed systems with minimal release.

This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals and rubber products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and laboratory work.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), of substances in closed systems with minimal release, as processing aid, manufacturing of the substance, formulation of mixtures, in the production of articles, as processing aid and for thermoplastic manufacture.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, in processing aids at industrial sites and as processing aid.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: keep away from heat, sparks, open flames and/or hot surfaces – No smoking; obtain special instructions before use; avoid release to the environment; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If swallowed: immediately call a poison center or doctor/physician. Do not induce vomiting.

Storage statements

Store this substance in a well-ventilated place and keeping container tightly closed.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • DOMO Caproleuna GmbH, Am Haupttor Bau 3101 06237 Leuna Germany
  • OMV PETROM S.A., 22 Coralilor Street (“Petrom City”) Sector 1 013329 Bucharest Romania
  • Total Raffinage France, 2, place Jean Millier, La Défense 92400 Courbevoie France
  • EcoMole s.r.o., U vetrniku 40/1 16200 Prague 6 Czech Republic

Substance names and other identifiers

[A complex combination of hydrocarbons obtained from distillation of products from a catalytic reforming process. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C5 through C8 and boiling in the range of approximately 35°C to 120°C (95°F to 248°F). It contains a relatively large proportion of branched chain hydrocarbons with the aromatic components removed.]
A complex combination of hydrocarbons obtained from distillation of products from a catalytic reforming process. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C5 through C8 and boiling in the range of approximately 35°C to 120°C (95°F to 248°F). It contains a relatively large proportion of branched chain hydrocarbons with the aromatic components removed.
C&L Inventory
Dearomatized light catalytic reformed naphtha
A complex combination of hydrocarbons obtained from distillation of products from a catalytic reforming process. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C5 through C8 and boiling in the range of approximately 35°C to 120°C (95°F to 248°F). It contains a relatively large proportion of branched chain hydrocarbons with the aromatic components removed.
Other
Low boiling point cat-reformed naphtha
A complex combination of hydrocarbons obtained from distillation of products from a catalytic reforming process. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C5 through C8 and boiling in the range of approximately 35°C to 120°C (95°F to 248°F). It contains a relatively large proportion of branched chain hydrocarbons with the aromatic components removed.
C&L Inventory
Naphtha (petroleum), light catalytic reformed, arom.-free
EC Inventory, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances
Naphtha (petroleum), light catalytic reformed, arom.-free
A complex combination of hydrocarbons obtained from distillation of products from a catalytic reforming process. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C5 through C8 and boiling in the range of approximately 35°C to 120°C (95°F to 248°F). It contains a relatively large proportion of branched chain hydrocarbons with the aromatic components removed.
C&L Inventory, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances
Naphtha (petroleum), light catalytic reformed, arom.-free; Low boiling point cat-reformed naphtha [ complex combination of hydrocarbons obtained from distillation of products from a catalytic reforming process. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C5 through C8 and boiling in the range of approxi mately 35o C to 120o C (95 °F to 248 °F). It contains a relatively large proportion of branched chain hydrocarbons with the aromatic components removed.]
A complex combination of hydrocarbons obtained from distillation of products from a catalytic reforming process. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C5 through C8 and boiling in the range of approximately 35°C to 120°C (95°F to 248°F). It contains a relatively large proportion of branched chain hydrocarbons with the aromatic components removed.
CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
Naphtha (petroleum), light catalytic reformed, arom.-free; Low boiling point cat-reformed naphtha
A complex combination of hydrocarbons obtained from distillation of products from a catalytic reforming process. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C5 through C8 and boiling in the range of approximately 35°C to 120°C (95°F to 248°F). It contains a relatively large proportion of branched chain hydrocarbons with the aromatic components removed.
FCM Active and Intelligent Materials - CMRs not allowed for use, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, Workplace Signs - minimum requirements & signs on containers and pipes, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes
Naphtha, petroleum, light catalytic reformed, arom-free
A complex combination of hydrocarbons obtained from distillation of products from a catalytic reforming process. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C5 through C8 and boiling in the range of approximately 35°C to 120°C (95°F to 248°F). It contains a relatively large proportion of branched chain hydrocarbons with the aromatic components removed.
Other
(Keerulise koostisega süsivesinike segu, mis saadakse katalüütilise reformingu produktide destillatsioonil. Koosneb peamiselt süsivesinikest, mille süsiniku aatomite arv on valdavalt vahemikus C5 kuni C8, ning on keemistemperatuuriga umbes 35°C kuni 120 °C. Sisaldab suhteliselt suurel hulgal hargnenud ahelaga süsivesinikke, mille aromaatsed komponendid on kõrvaldatud.] (et)
C&L Inventory
(Složeni sastav ugljikovodika dobiven kod destilacije proizvoda iz postupka katalitičkog reforminga. Sastoji se pretežito od ugljikovodika koji imaju broj ugljikovih atoma pretežito u području od C5 do C8 i vriju u području približno od 35 °C do 120 °C. Sadrži razmjerno velik udio razgrananih ugljikovodika iz kojih su uklonjene aromatske komponente.) (hr)
C&L Inventory
[Kompleks blanding av hydrokarboner dannet ved destillasjon av produkter fra katalytisk reformering. Består for det meste av hydrokarboner, hovedsakelig C5 til C8, med omtrentlig kokepunktsintervall fra 35 °C til 120 °C (95 °F til 248 °F). Inneholder en relativt stor andel forgrenede hydrokarboner der de aromatiske komponentene er fjernet.] (no)
C&L Inventory
[Kompleksna kombinacija ogljikovodikov dobljena z destilacijo produktov iz katalitskega reforming procesa. Sestoji pretežno iz ogljikovodikov s številom ogljikovih atomov pretežno v območju med C5 in C8 ter z vreliščem v območju med 35 °C in 120 °C.) Vsebuje relativno visok delež razvejanih ogljikovodikov brez aromatskih komponent.] (sl)
C&L Inventory
[komplexe Kombination von Kohlenwasserstoffen aus der Destillation von Produkten aus einem katalytischen Reformierverfahren; besteht vorwiegend aus Kohlenwasserstoffen mit Kohlenstoffzahlen überwiegend im Bereich von C5 bis C8 mit einem Siedebereich von etwa 35 °C bis 120 °C; enthält eine relativ große Menge an von aromatischen Bestandteilen befreiten verzweigten Kohlenwasserstoffen] (de)
C&L Inventory
[Komplexná zmes uhľovodíkov získavaná destiláciou produktov z procesu katalytického reformovania. Pozostáva predovšetkým z uhľovodíkov s počtom atómov uhlíka prevažne v rozmedzí od C5 do C8. Má teplotu varu v rozmedzí približne od 35 °C do 120 °C. Obsahuje relatívne veľký podiel uhľovodíkov s rozvetveným reťazcom s odstránenými aromatickými zložkami.] (sk)
C&L Inventory
[O combinaţie complexă de hidrocarburi obţinută prin distilarea produşilor unui proces de reformare catalitică. Constă cu precădere în hidrocarburi al căror număr de atomi de carbon variază între C 5 şi C8 şi al căror punct de fierbere este situat între 35°C şi 120°C (95°F şi 248°F). Conţine o cantitate relativ mare de hidrocarburi cu catenă ramificată, din care au fost îndepărtate componentele aromatice.] (ro)
C&L Inventory
[Ogļūdeņražu savienojumu komplekss, kas iegūts, destilējot katalītiskā riforminga procesa produktus. Sastāv pārsvarā no ogļūdeņražiem, pārsvarā ar oglekļa atomu skaitu no C5 līdz C8, aptuvenā viršanas temperatūra no 35°C līdz 120°C (95°F līdz 248°F). Satur relatīvi daudz sazarotās ķēdes ogļūdeņražu, kas atbrīvoti no aromātiskajiem savienojumiem.] (lv)
C&L Inventory
[Složitá směs uhlovodíků získaná destilací produktů z katalytického reformování. Je složena převážně z uhlovodíků s počtem uhlíkových atomů převážně v rozmezí C5 až C8 a s rozmezím teplot varu přibližně v 35 °C až 120 °C. Obsahuje relativně velký podíl uhlovodíků s rozvětveným řetězcem, aromatické složky byly odstraněny.] (cs)
C&L Inventory
[Sudėtinis angliavandenilių mišinys, gaunamas distiliuojant katalizinio riformingo produktus. Jį sudaro daugiausia angliavandeniliai, turintys anglies atomų skaičių daugiausia nuo C5 iki C8, ir kurių virimo temperatūra maždaug nuo 35 °C iki 120 °C (nuo 95 °F iki 248 °F). Palyginti didelę jo dalį sudaro šakotos grandinės angliavandeniliai, pašalinus aromatinius komponentus.] (lt)
C&L Inventory
[Szénhidrogének komplex elegye, melyet katalitikus reformálási folyamat termékeinek desztillációjából nyernek. Főleg szénhidrogénekből áll, melyek szénatomszáma főleg a C5-C8 tartományban van, és a forráspont tartománya kb. 35°C-tól 120°C-ig (95°F-től 248°F-ig) terjed. Viszonylag jelentős arányban tartalmaz elágazó láncú szénhidrogéneket, melyekből az aromás komponenseket eltávolították.] (hu)
C&L Inventory
[Πολύπλοκος συνδυασμός υδρογονανθράκων που λαμβάνεται από την απόσταξη προϊόντων καταλυτικής αναμόρφωσης. Συνίσταται κυρίως από υδρογονάνθρακες με αριθμό ατόμων άνθρακα κυρίως μεταξύ C5 και C8 που αποστάζουν μεταξύ 35 °C και 120 °C περίπου. Περιέχει σχετικά μεγάλη αναλογία υδρογονανθράκων διακλαδισμένης αλυσίδας, ενώ τα αρωματικά συστατικά έχουν απομακρυνθεί.] (el)
C&L Inventory
[Комплексна комбинация от въглеводороди, получена при дестилация на продукти от каталитичен реформинг процес. Състои се основно от въглеводороди с брой на въглеродните атоми в интервала от C5 до C8 включително и с температура на кипене приблизително в интервала от 35°C до 120°C (95°F до 248°F). Съдържа относително голямо количество от разклонени въглеводороди, очистени от ароматни съставки. ] (bg)
C&L Inventory
Alacsony forráspontú kat-reformált benzin (hu)
C&L Inventory
Benzin (nafta), laki kat. reformiran, bez aromata (hr)
C&L Inventory
Benzin (nyersolaj), könnyű katalitikusan reformált, aromásoktól mentes (hu)
C&L Inventory
Benzyna lekka z reformingu katalitycznego, wolna od węglowodorów aromatycznych (ropa naftowa) (pl)
C&L Inventory
Benzínová frakce (ropná), lehká frakce katalyticky reformovaná, bez aromátů (cs)
C&L Inventory
combinación compleja de hidrocarburos obtenida de la destilación de productos de un proceso de reformado catalítico; compuesta principalmente de hidrocarburos con un número de carbonos en su mayor parte dentro del intervalo de C5 a C8 y con un intervalo de ebullición aproximado de 35 °C a 120 °C; contiene una proporción relativamente grande de hidrocarburos de cadena ramificada con los componentes aromáticos separados (es)
C&L Inventory
Combinaison complexe d'hydrocarbures obtenue par distillation des produits résultant d'un reformage catalytique. Se compose principalement d'hydrocarbures dont le nombre de carbones se situe en majorité dans la gamme C5-C8 et dont le point d'ébullition est compris approximativement entre 35°C et 120°C. Contient une proportion relativement importante d'hydrocarbures à chaînes ramifiées dont les composants aromatiques ont été éliminés. (fr)
C&L Inventory
Combinazione complessa di idrocarburi prodotta per distillazione dei prodotti provenienti da un processo di reforming catalitico. È costituita in prevalenza da idrocarburi con numero di atomi di carbonio prevalentemente nell'intervallo C5-8 e punto di ebollizione nell'intervallo 35 °C - 120 °C ca. (da 95°F a 248°F). Contiene una percentuale relativamente alta di idrocarburi a catena ramificata dai quali sono stati separati i componenti aromatici. (it)
C&L Inventory
Combinação complexa de hidrocarbonetos obtida por destilação dos produtos de um processo de reformação catalítica. É constituída predominantemente por hidrocarbonetos com número de átomos de carbono predominantemente na gama C5 a C8 e destilação no intervalo aproximado de 35 °C a 120 °C. Contém uma proporção relativamente elevada de hidrocarbonetos de cadeia ramificada, tendo sido removidos os componentes aromáticos. (pt)
C&L Inventory
Een complexe verzameling koolwaterstoffen, verkregen door destillatie van producten uit een katalytisch reformingproces. Bestaat voornamelijk uit koolwaterstoffen, overwegend C5 tot en met C8, met een kooktraject van ongeveer 35°C tot 120°C. Bevat een relatief grote hoeveelheid vertakte koolwaterstoffen en de aromatische bestanddelen zijn verwijderd. (nl)
C&L Inventory
En sammensat blanding af carbonhydrider opnået ved destillationen af produkterne fra en katalytisk reformeringsproces. Den består overvejende af carbonhydrider, overvejende C5 til og med C8, med kogeinterval omtrent fra 35 °C til 120 °C (95 ºF til 248 ºF). Den indeholder en forholdsvis stor del forgrenede carbonhydrider, hvorfra de aromatiske komponenter er fjernet. (da)
C&L Inventory
Fracţia nafta (petrol), uşor reformat catalitic, fără compuşi aromatici (mt)
C&L Inventory
Fracţia nafta (petrol), uşor reformat catalitic, fără compuşi aromatici (ro)
C&L Inventory
Fracţia nafta cu punct de fierbere la temperaturi scăzute reformată catalitic (mt)
C&L Inventory
Fracţia nafta cu punct de fierbere la temperaturi scăzute reformată catalitic (ro)
C&L Inventory
katalitsko reformirana nafta z nizko temperaturo vrelišča (sl)
C&L Inventory
katalyticky reformovaný ťažký benzín s nízkou teplotou varu (sk)
C&L Inventory
Katalytisch gereformde nafta met laag kookpunt (nl)
C&L Inventory
katalytisch reformiertes Naphtha, niedrigsiedend (de)
C&L Inventory
Katalītiski riformēts ligroīns ar zemu viršanas temperatūru (lv)
C&L Inventory
Komplex blandning av kolväten erhållen genom destillation av produkter från katalytisk reformering. Består främst av kolväten, i synnerhet C5 till C8, med ungefärligt kokpunktsintervall från 35 °C till 120 °C. Innehåller relativt stor andel grenade kolväten med aromatiska komponenter borttagna. (sv)
C&L Inventory
Lavtkogende katalytisk reformeret nafta (da)
C&L Inventory
lavtkokende katalytisk reformert nafta (no)
C&L Inventory
Ligroīns (nafta), vieglais, katalītiski riformēts, nesatur aromātiskos savienojumus (lv)
C&L Inventory
Lågkokande katalytiskt reformerad nafta (sv)
C&L Inventory
Madala keemispunktiga katalüütiliselt reformitud raskbensiin (et)
C&L Inventory
Matalalla kiehuva katalyyttisesti reformoitu teollisuusbensiini (fi)
C&L Inventory
Monimutkainen seos hiilivetyjä, saatu katalyyttisen reformointiprosessin tuotteiden tislauksesta. Koostuu pääasiassa hiilivedyistä, joiden hiililuvut ovat pääasiassa välillä C5:sta C8:een ja jotka kiehuvat likimäärin välillä 35°C:sta 120°C:een (95°F:sta 248°F:iin). Sisältää suhteellisen suuren osan haarautunutketjuisia hiilivetyjä, joista aromaattiset ainesosat poistettu. (fi)
C&L Inventory
Nafta (aardolie), lichte katalytisch gereformde, vrij van aromaten (nl)
C&L Inventory
nafta (petroleum), lett katalytisk reformert, aromatfri (no)
C&L Inventory
Nafta (petroleum), lätt, katalytiskt reformerad, aromatfri (sv)
C&L Inventory
nafta (petrolio), taglio leggero di reforming catalitico, privo di composti aromatici (it)
C&L Inventory
nafta (petróleo), fracción ligera reformada catalíticamente, libre de aromáticos (es)
C&L Inventory
Nafta (petróleo), fracção leve de reformação catalítica, desaromatizada (pt)
C&L Inventory
nafta (zemeljsko olje), lahka katalitsko reformirana, brez aromatov (sl)
C&L Inventory
Nafta de baixo ponto de ebulição de reformação catalítica (pt)
C&L Inventory
nafta di reforming catalitico con basso punto di ebollizione (it)
C&L Inventory
nafta reformada catalíticamente de bajo punto de ebullición (es)
C&L Inventory
naphta de reformage catalytique à point d'ébullition bas (fr)
C&L Inventory
Naphta léger de reformage catalytique (pétrole), non aromatique; naphta de reformage catalytique à bas point d'ébullition;[Combinaison complexe d'hydrocarbures obtenue par distillation des produits résultant d'un reformage catalytique. Se compose principalement d'hydrocarbures comportant majoritairement entre 5 et 8 atomes de carbone (C5-C8) et dont l'intervalle d'ébullition est compris approximativement entre 35 et 120 oC (entre 95 et 248o F).] Contient une proportion relativement importante d'hydrocarbures ramifiés, tandis que les composés aromatiques ont été éliminés. (fr)
C&L Inventory
Naphtha (Erdöl), leicht, katalytisch reformiert, aromatenfrei (de)
C&L Inventory
naphtha (råolie), let katalytisk reformeret, aromatfri (da)
C&L Inventory
Nisko-vrijući kat. reformiran benzin (hr)
C&L Inventory
Niskowrząca benzyna z reformingu katalitycznego (pl)
C&L Inventory
Nízkovroucí katalyticky reformovaná benzínová frakce (cs)
C&L Inventory
O combinaţie complexă de hidrocarburi obţinută prin distilarea produşilor unui proces de reformare catalitică. Constă cu precădere în hidrocarburi al căror număr de atomi de carbon variază între C 5 şi C8 şi al căror punct de fierbere este situat între 35°C şi 120°C (95°F şi 248°F). Conţine o cantitate relativ mare de hidrocarburi cu catenă ramificată, din care au fost îndepărtate componentele aromatice. (mt)
C&L Inventory
Pirminis benzinas (nafta), katalizinio riformingo lengvasis, neturi aromatinių angliavandenilių (lt)
C&L Inventory
Raskbensiin (nafta), kerg-katalüütiliselt reformitud, aromaatsete ühendite vaba (et)
C&L Inventory
Teollisuusbensiini (maaöljy), kevyt katalyyttisesti reformoitu, aromaattivapaa (fi)
C&L Inventory
Złożona mieszanina węglowodorów otrzymywana podczas destylacji produktów z procesu reformingu katalitycznego. Składa się przede wszystkim z węglowodorów o liczbie atomów węgla głównie w zakresie od C5 do C8, wrzących w zakresie temp. od ok. 35°C do 120°C. Zawiera stosunkowo dużą ilość węglowodorów o rozgałęzionych łańcuchach węglowych przy usunięciu składników aromatycznych (pl)
C&L Inventory
ťažký benzín (ropný), ľahká frakcia, z katalytického zušľachťovania, zbavený aromatických uhľovodíkov (sk)
C&L Inventory
Žematemperatūris katalizinio riformingo pirminis benzinas (lt)
C&L Inventory
Νάφθα χαμηλού σημείου ζέσεως από καταλυτική αναμόρφωση (el)
C&L Inventory
νάφθαΝάφθα (πετρελαίου), ελαφρά, καταλυτικά αναμορφωμένη, απαλλαγμένη από αρωματικές ενώσεις (el)
C&L Inventory
Нискооктанов бензин (нефт), лек от каталитичен реформинг, не съдържа ароматни въглеводороди (bg)
C&L Inventory
Нискооктанов бензин от каталитичен реформинг с ниска температура на кипене, (bg)
C&L Inventory
Naphtha (petroleum), light catalytic reformed, arom.-free
Other
C7-Fraktion / Naphtha (petroleum), light catalytic reformed, aromatic free
Registration dossier
Naphtha
C&L Inventory
Naphtha (petroleum), light catalytic reformed, arom.-free
C&L Inventory, Registration dossier
Naphtha (petroleum), light catalytic reformed, arom.-free
Registration dossier
Naphtha (petroleum), light catalytic reformed, arom.-free / Naphtha (petroleum), light catalytic reformed, arom.-free
Registration dossier
Gasoline component (raffinate)
Registration dossier
101316-77-2
CAS number
Other
101316-77-2
Deleted CAS number
Other
649-304-00-0
Index number
C&L Inventory
68513-03-1
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 2 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [2]
C Form
Other (100%) [2]
C Substance type
Petroleum product (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Melting/freezing point

Study results
  • 3 studies submitted
  • 1 study processed
R Melting / freezing point
-60 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Boiling point

Study results
  • 4 studies submitted
  • 2 studies processed
R Boiling point
-20 - 260 °C @ 101.325 kPa [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Density

Study results
  • 2 studies submitted
  • 2 studies processed
R Relative density
0.62 - 0.88 @ 15 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Vapour pressure

Study results
  • 2 studies submitted
  • 2 studies processed
R Vapour pressure
240 kPa @ 37.8 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Partition coefficient

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Water solubility

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 2 studies submitted
  • 2 studies processed
R Flash point
-40 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 8 studies submitted
  • 4 studies processed
R Autoflammability / self-ignition
280 - 470 °C @ 101.3 - 101.325 kPa [4]

Type of Study provided
Studies with data
Key study 2 2
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 2 studies submitted
  • 2 studies processed
C Interpretation of results
Extremely flammable (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Flammability
Extremely flammable (100%)

Explosiveness

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 4 studies submitted
  • 2 studies processed
R kinematic viscosity (in mm²/s)
1 [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water - screening tests

Study results
  • 14 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 12
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Adsorption/desorption

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Study results
  • 1 study submitted
  • 1 study processed
% Distribution in Media:
R Air 93.02 % [1]
R Water 5.83 % [1]
R Soil 0.34 % [1]
R Sediment 0.81 % [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 2 summaries submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No data available: testing technically not feasible (1)
Intermittent releases (freshwater) No data available: testing technically not feasible (1)
Marine water No data available: testing technically not feasible (1)
Intermittent releases (marine water) No data available: testing technically not feasible (1)
Sewage treatment plant (STP) No data available: testing technically not feasible (1)
Sediment (freshwater) No data available: testing technically not feasible (1)
Sediment (marine water) No data available: testing technically not feasible (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil No data available: testing technically not feasible (1)
Hazard for Predators
Secondary poisoning Insufficient hazard data available (further information necessary) (1)

Short–term toxicity to fish

Study results
  • 32 studies submitted
  • 4 studies processed
P/RResults
LL50 (4 days) 8.2 - 10 mg/L [4]

Type of Study provided
Studies with data
Key study 4
Supporting study 28
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 4 studies submitted
  • 2 studies processed
P/RResults
EL50 (21 days) 10 mg/L [2]
NOELR (21 days) 2.6 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 24 studies submitted
  • 2 studies processed
P/RResults
EL50 (48 h) 4.5 mg/L [2]
NOELR (48 h) 500 µg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 22
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 6 studies submitted
  • 2 studies processed
P/RResults
NOELR (21 days) 2.6 - 16 mg/L [4]
EL50 (21 days) 10 - 40 mg/L [4]

Type of Study provided
Studies with data
Key study 2
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 32 studies submitted
  • 2 studies processed
P/RResults
EL50 (4 days) 3.7 mg/L [2]
EL50 (72 h) 3.1 mg/L [2]
NOELR (72 h) 500 µg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 30
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC50 (40 h) 15.41 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 3 summaries submitted
  • 2 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 1.9 mg/m³ repeated dose toxicity
Acute /short term: (DNEL) 1 286.4 mg/m³ neurotoxicity
Local Effects
Long-term: (DNEL) 837.5 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 1 066.67 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: High hazard (no threshold derived)
Acute /short term: High hazard (no threshold derived)
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 410 µg/m³ repeated dose toxicity
Acute /short term: (DNEL) 1 152 mg/m³ neurotoxicity
Local Effects
Long-term: (DNEL) 178.57 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 640 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: High hazard (no threshold derived)
Acute /short term: High hazard (no threshold derived)
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 87 studies submitted
  • 2 studies processed
P/RResults
LD50 5 000 mg/kg bw (rat) [2]
M/CInterpretations of results
Not classified [2]

Type of Study provided
oral
Studies with data
Key study 1 1
Supporting study 45 40
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 79 studies submitted
  • 4 studies processed
M/CInterpretations of results
Not classified [4]

inhalation
Studies with data
Key study 3 1
Supporting study 36 39
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 89 studies submitted
  • 2 studies processed
P/RResults
LD50 2 000 mg/kg bw (rabbit) [2]
M/CInterpretations of results
Not classified [2]

dermal
Studies with data
Key study 1 1
Supporting study 44 43
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Oral route:
No adverse effect observed LD50 5 000 mg/kg bw
Inhalation route:
No adverse effect observed LC50 5 610 mg/m³
Dermal route:
No adverse effect observed LD50 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 209 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1 1
Supporting study 116 90
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 90 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1 1
Supporting study 44 43
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Skin
Adverse effect observed (irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 86 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1 1
Supporting study 42 41
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 10 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Study data: oral
Studies with data
Key study 1
Supporting study 5 4
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 44 studies submitted
  • 2 studies processed
P/RResults
NOAEC (rat): 9.84 - 20 mg/L air [3]

Study data: inhalation
Studies with data
Key study 3 1
Supporting study 19 21
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 102 studies submitted
  • 8 studies processed
P/RResults
NOAEL (rat): 375 - 3 750 mg/kg bw/day [2]
NOEL (rabbit): 200 - 2 000 mg/kg bw/day [14]

Study data: dermal
Studies with data
Key study 9 1
Supporting study 43 49
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Inhalation route - systemic effects:
No adverse effect observed NOAEC 1 402 mg/m³ (chronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 43 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 2 3
Supporting study 19 18
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: in vivo
  • 28 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 2 1
Supporting study 12 13
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Toxicity - InVivo
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 24 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1 2
Supporting study 12 9
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Inhalation route:
No adverse effect observed NOAEC 9 869 mg/m³ (chronic, rat)

Toxicity to reproduction

Study results
Study data: reproduction
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 2 1
Supporting study 2 3
Weight of evidence
Other
Data waiving
no waivers
Study data: developmental
  • 17 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 1 2
Supporting study 7 6
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Effect on fertility
Inhalation route:
No adverse effect observed NOAEC 20 000 mg/m³ (chronic, rat)
Effect on developmental toxicity
Dermal route:
No adverse effect observed NOAEL 500 mg/kg bw/day (subchronic, rat)
Inhalation route:
No adverse effect observed NOAEC 23 900 mg/m³ (subchronic, rat)

Neurotoxicity

Study results
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study 2 3
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 1 3
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant