Brief Profile

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
272-186-3
CAS no.:
68783-12-0
Index number:
649-271-00-2
Molecular formula:
SMILES:
InChI:
Type of substance:
UVCB
Origin:
Petroleum product
Registered compositions:
28
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP01) approved by the European Union, this substance may be fatal if swallowed and enters airways, may cause genetic defects and may cause cancer.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is toxic to aquatic life with long lasting effects, is an extremely flammable liquid and vapour, is suspected of damaging fertility or the unborn child, causes skin irritation and may cause drowsiness or dizziness.

Breakdown of all 290 C&L notifications submitted to ECHA

Asp. Tox. 1 H304 Harmonised Classification
Aquatic Chronic 2 H411
Skin Irrit. 2 H315
STOT SE 3 H336
Repr. 2 H361
Muta. 1B H340 Harmonised Classification
Carc. 1B H350 Harmonised Classification
Flam. Liq. 1 H224
Flam. Liq. 2 H225
Flam. Liq. 3 H226
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • C
Officially recognised in the EU as Carcinogenic (Harmonised C&L).
  • C
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Carcinogenic (45.45% of REACH registrations).
  • M
Officially recognised in the EU as Mutagenic (Harmonised C&L).
  • M
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Mutagenic (45.45% of REACH registrations).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 24 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 000 to < 10 000 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: fuels, air care products, anti-freeze products, coating products, lubricants and greases, washing & cleaning products and welding & soldering products.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids), indoor use as processing aid and outdoor use as processing aid.

This substance is used in the following activities or processes at workplace: production of mixtures or articles by tabletting, compression, extrusion or pelletisation and the low energy manipulation of substances bound in materials or articles.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, manufacturing of the substance, formulation of mixtures, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid and of substances in closed systems with minimal release.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the types of manufacture using this substance.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and in materials as fuel sources, with limited exposure to unburned product to be expected.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids), indoor use as processing aid and outdoor use as processing aid.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and laboratory work.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, manufacturing of the substance, formulation in materials, in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture, as processing aid and of substances in closed systems with minimal release.

This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals and rubber products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and laboratory work.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, manufacturing of the substance, as an intermediate step in further manufacturing of another substance (use of intermediates), formulation of mixtures, of substances in closed systems with minimal release and as processing aid.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, in processing aids at industrial sites, as processing aid, formulation of mixtures, formulation in materials, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture and of substances in closed systems with minimal release.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: keep away from heat, sparks, open flames and/or hot surfaces – No smoking; obtain special instructions before use; avoid release to the environment; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If swallowed: immediately call a poison center or doctor/physician. Do not induce vomiting.

Storage statements

Store this substance in a well-ventilated place and keeping container tightly closed.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • BCS Only Representative Services Ltd 027, Pembroke House 30 Upper Pembroke Street Dublin 2 Dublin Ireland
  • BP Europa SE (OR), Überseeallee 1 20457 Hamburg Germany
  • Equinor ASA, Forusbeen 50 N-4035 Stavanger Norway
  • ESSO Italiana Srl, Viale Castello della Magliana 25 00148 Roma Italy
  • Esso Nederland B.V., Graaf Engelbertlaan 75 4837 DS Breda Netherlands
  • Esso Raffinage S.A.S., 20 Rue Paul Heroult 92000 Nanterre France
  • ExxonMobil Petroleum & Chemical BV, Polderdijkweg 2030 Antwerpen Belgium
  • Gunvor Petroleum Antwerpen NV, Scheldelaan 490 2040 Antwerp Belgium
  • Gunvor Petroleum Rotterdam B.V., Moezelweg 255 3198 LS Europoort Netherlands
  • Gunvor Raffinerie Ingolstadt GmbH, Essostrasse 1 85092 Kösching Germany
  • Hellenic Petroleum S.A., 8Α Chimarras st. GR 15125 Maroussi Attica Greece
  • ISAB S.r.l., ex S.s. 114 km 146 96010 Priolo Gargallo (SR) Sicily Italy
  • Petroplus Raffinage Petit Couronne SAS, Rue Aristide Briand 72 76650 Petit Couronne France
  • Petroplus Raffinage Reichstett SAS, Route Départementale 37 67116 Reichstett France
  • PETROTEL-LUKOIL S.A., 235 Mihai Bravu 100410 Ploiesti Romania
  • REACH GLOBAL SERVICES S.A., Rond Point Schuman, 6 B-1040 Brusssels Belgium
  • REACHLaw Ltd., Vänrikinkuja 3 JK 21 FI-02600 Espoo Finland
  • Sasol Italy S.p.A., Viale Enrico Forlanini 23 I-20134 Milan Italy
  • Shell Trading Rotterdam B. V., Weena 70 3012 CM Rotterdam Netherlands
  • Sonatrach Raffineria Italiana S.r.l., Via Alessandro Manzoni, 38 20121 Milano Italy
  • TOTAL DEUTSCHLAND GmbH, Jean-Monnet-Straße 2 10 117 BERLIN Germany
  • Total Raffinage France, 2, place Jean Millier, La Défense 92400 Courbevoie France
  • TotalEnergies Trading Europe, 2 Place Jean Millier La Défense 6 92400 Courbevoie France
  • Valero Energy (Ireland) Limited, 1st Floor, Block B Liffey Valley Office Campus D22 X0Y3 Quarryvale Dublin 22 Ireland
  • Borealis AG, Wagramerstrasse 17-19 1220 Wien Austria
  • BP Oil International, Chertsey Road TW16 7BP Sunbury on Thames Middlesex United Kingdom
  • Esso Norge AS, Grenseveien 6 4313 Sandnes Norway
  • Esso Petroleum Company Ltd., Ermyn Way ExxonMobil House KT22 8UX Surrey Leatherhead United Kingdom
  • Esso SAF, 20 Rue Paul Heroult 92000 Nanterre France
  • INEOS Sales UK Ltd (O&P North), Hawklease Chapel Lane SO43 7FG Lyndhurst Hampshire United Kingdom
  • Interchem Logistics B.V., Javastraat 4 3016 CE Rotterdam Netherlands
  • Morgan Stanley & Co. international Plc, 25 Cabot square E14 4QA London United Kingdom
  • Only representative (No publishable name), null
  • Petrobras Global Trading B.V., Weena 762 - 9th Floor First Rotterdam 3014 DA Rotterdam Netherlands
  • PETROBRAS GLOBAL TRADING BV - PGT BV, Weena 762 - 9th Floor, First Rotterdam 3014 DA Rotterdam Netherlands
  • Petroineos Trading Limited, 11th Floor, The Adelphi, 1-11 John Adam Street, WC2N 6HT London United Kingdom
  • Petroplus Refining and Marketing Limited, Coryton Refinery The Manorway SS17 9LL Stanford-le-Hope Essex United Kingdom
  • SARPOM S.r.l., Viale Castello della Magliana 25 00148 Roma Italy
  • Shell Trading International Ltd, Shell Centre SE1 7NA London United Kingdom
  • Total Lindsey Oil Refinery ltd, Eastfield Road DN40 3LW North Lincolnshire United Kingdom

Substance names and other identifiers

[A complex combination of hydrocarbons produced from the distillation of naphtha streams from various refinery processes. It consists of hydrocarbons having carbon numbers predominantly in the range of C5 through C12 and boiling in the range of approximately 0°C to 230°C (25°F to 446°F).]
A complex combination of hydrocarbons produced from the distillation of naphtha streams from various refinery processes. It consists of hydrocarbons having carbon numbers predominantly in the range of C5 through C12 and boiling in the range of approximately 0°C to 230°C (25°F to 446°F).
C&L Inventory
Low boiling point naphtha
A complex combination of hydrocarbons produced from the distillation of naphtha streams from various refinery processes. It consists of hydrocarbons having carbon numbers predominantly in the range of C5 through C12 and boiling in the range of approximately 0°C to 230°C (25°F to 446°F).
C&L Inventory
Naphtha (petroleum), unsweetened
EC Inventory, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances
Naphtha (petroleum), unsweetened
A complex combination of hydrocarbons produced from the distillation of naphtha streams from various refinery processes. It consists of hydrocarbons having carbon numbers predominantly in the range of C5 through C12 and boiling in the range of approximately 0°C to 230°C (25°F to 446°F).
C&L Inventory, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances
Naphtha (petroleum), unsweetened; Low boiling point naphtha [ complex combination of hydrocarbons produced from the distillation of naphtha streams from various refinery processes. It consists of hydrocarbons having carbon numbers predominantly in the range of C5 through C12 and boiling in the range of approximately 0 °C to 230 °C (25°F to 446°F).]
A complex combination of hydrocarbons produced from the distillation of naphtha streams from various refinery processes. It consists of hydrocarbons having carbon numbers predominantly in the range of C5 through C12 and boiling in the range of approximately 0°C to 230°C (25°F to 446°F).
CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
Naphtha (petroleum), unsweetened; Low boiling point naphtha
A complex combination of hydrocarbons produced from the distillation of naphtha streams from various refinery processes. It consists of hydrocarbons having carbon numbers predominantly in the range of C5 through C12 and boiling in the range of approximately 0°C to 230°C (25°F to 446°F).
FCM Active and Intelligent Materials - CMRs not allowed for use, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, Workplace Signs - minimum requirements & signs on containers and pipes, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes
Naphtha, petroleum, unsweetened
A complex combination of hydrocarbons produced from the distillation of naphtha streams from various refinery processes. It consists of hydrocarbons having carbon numbers predominantly in the range of C5 through C12 and boiling in the range of approximately 0°C to 230°C (25°F to 446°F).
Other
Unsweetened naphtha (petroleum)
A complex combination of hydrocarbons produced from the distillation of naphtha streams from various refinery processes. It consists of hydrocarbons having carbon numbers predominantly in the range of C5 through C12 and boiling in the range of approximately 0°C to 230°C (25°F to 446°F).
Other
(Keerulise koostisega süsivesinike segu, mis tekib nafta destillatsioonil mitmesugustel rafineerimisprotsessidel . Koosneb süsivesinikest, mille süsiniku aatomite arv on valdavalt vahemikus C5 kuni C12, ning on keemistemperatuuriga umbes 0°C –230 °C.) (et)
C&L Inventory
(Složeni sastav ugljikovodika proizveden destilacijom benzinskih struja iz različitih rafinerijskih postupaka. Sastoji se od ugljikovodika koji imaju broj ugljikovih atoma pretežito u području od C5 do C12 i vriju u području približno od 0 ºC do 230 ºC.) (hr)
C&L Inventory
[Kompleks blanding av hydrokarboner fremstilt ved destillasjon av naftastrømmer fra forskjellige raffineriprosesser. Består av hydrokarboner, hovedsakelig C5 til C12, med omtrentlig kokepunktsintervall fra 0 °C til 230 °C (25 °F til 446 °F).] (no)
C&L Inventory
[Kompleksna kombinacija ogljikovodikov proizvedena z destilacijo produktov iz katalitskega reforming procesa. Sestoji iz ogljikovodikov s številom ogljikovih atomov pretežno v območju med C5 in C12 ter ima vrelišče v območju približno med 0 °C in 230 °C.] (sl)
C&L Inventory
[komplexe Kombination von Kohlenwasserstoffen aus der Destillation von Naphthaläufen aus verschiedenen Raffinerieverfahren; besteht aus Kohlenwasserstoffen mit Kohlenstoffzahlen vorwiegend im Bereich von C5 bis C12 mit einem Siedebereich von etwa 0 °C bis 230 °C] (de)
C&L Inventory
[Komplexná zmes uhľovodíkov záskavaná destiláciou benzínov z rôznych rafinačných procesov. Pozostáva z uhľovodíkov s počtom atómov uhlíka prevažne v rozmedzí od C5 do C12. Má teplotu varu v rozmedzí približne od 0 °C do 230 °C.] (sk)
C&L Inventory
[O combinaţie complexă de hidrocarburi produsă în urma distilării vaporilor fracţiei nafta rezultaţi din diferite procese de rafinare. Constă în hidrocarburi al căror număr de atomi de carbon variază între C5 până la C12 şi are puncte de fierbere cuprinse între aproximativ 0°C şi 230°C (25°F şi 446°F).] (ro)
C&L Inventory
[Ogļūdeņražu savienojumu komplekss, kas iegūts, destilējot ligroīna plūsmas no dažādiem rafinēšanas procesiem. Sastāv no ogļūdeņražiem, pārsvarā ar oglekļa atomu skaitu no C5 līdz C12, aptuvenā viršanas temperatūra no 0°C līdz 230°C (25°F līdz 446°F).] (lv)
C&L Inventory
[Složitá směs uhlovodíků produkovaná destilací benzínových proudů z různých rafinerských procesů. Je složena z uhlovodíků s počtem uhlíkových atomů převážně v rozmezí C5 až C12 a s rozmezím teploty varu přibližně 0 °C až 230 °C.] (cs)
C&L Inventory
[Sudėtinis angliavandenilių mišinys, gaunamas distiliuojant įvairių naftos perdirbimo procesų pirminio benzino srautus. Jį sudaro angliavandeniliai, turintys anglies atomų skaičių daugiausia nuo C5 iki C12, ir kurių virimo temperatūra maždaug nuo 0 °C iki 230 °C (nuo 25 °F iki 446 °F).] (lt)
C&L Inventory
[Szénhidrogének komplex elegye, melyet különféle finomítási folyamatokból származó benzin elegyek desztillációjából nyernek. Olyan szénhidrogénekből áll, melyek szénatomszáma főleg a C5-C12 tartományban van. Hozzávetőlegesen a 0°C-tól 230°C-ig (25°F-től 446°F-ig) terjedő tartományban forr.] (hu)
C&L Inventory
[Πολύπλοκος συνδυασμός υδρογονανθράκων, που λαμβάνεται από την απόσταξη ρευμάτων νάφθας από διάφορες διεργασίες διυλιστηρίου. Συνίσταται από υδρογονάνθρακες με αριθμό ατόμων άνθρακα κυρίως μεταξύ C5 και C12 που αποστάζουν μεταξύ 0 °C και 230 °C περίπου.] (el)
C&L Inventory
[Комплексна комбинация от въглевдодороди, получена при дестилация на бензинови потоци от различни процеси в рафинерията. Състои се от въглеводороди с брой на въглеродните атоми преобладаващо в интервала от C5 до C12 включително и с температура на кипене приблизително в интервала от 0°C до 230°C (25°F до 446°F).] (bg)
C&L Inventory
Alacsony forráspontú benzin (hu)
C&L Inventory
Benzin (nafta), neslađeni (hr)
C&L Inventory
Benzin (nyersolaj), nem kéntelenített (hu)
C&L Inventory
Benzyna nieodsiarczona (ropa naftowa) (pl)
C&L Inventory
Benzín (ropný), neslazený (cs)
C&L Inventory
benzín s nízkou teplotou varu (sk)
C&L Inventory
combinación compleja de hidrocarburos producida de la destilación de corrientes de nafta de diversos procesos de refinería; compuesta de hidrocarburos con un número de carbonos en su mayor parte dentro del intervalo de C5 a C12 y con un intervalo de ebullición aproximado de 0 °C a 230 °C (es)
C&L Inventory
Combinaison complexe d'hydrocarbures produite par distillation de fractions de naphta résultant de divers procédés de raffinerie. Se compose d'hydrocarbures dont le nombre de carbones se situe principalement dans la gamme C5-C12 et dont le point d'ébullition est compris approximativement entre 0°C et 230°C. (fr)
C&L Inventory
Combinazione complessa di idrocarburi ottenuta dalla distillazione di correnti di nafta provenienti da vari processi di raffineria. È costituita da idrocarburi con numero di atomi di carbonio prevalentemente nell'intervallo C5-12 e punto di ebollizione nell'intervallo 0 °C - 230 °C ca. (da 25°F a 446°F). (it)
C&L Inventory
Combinação complexa de hidrocarbonetos obtida por destilação de correntes de nafta provenientes de diversos processos de refinaria. É constituída por hidrocarbonetos com número de átomos de carbono predominantemente na gama C5 a C12 e destilação no intervalo aproximado de 0 °C a 230 °C. (pt)
C&L Inventory
Een complexe verzameling koolwaterstoffen, verkregen door destillatie van naftastromen uit verscheidene raffinageprocessen. Bestaat uit koolwaterstoffen, overwegend C5 tot en met C12, met een kooktraject van ongeveer 0°C tot 230°C. (nl)
C&L Inventory
En sammensat blanding af carbonhydrider fremstillet ved destillation af naphthastrømme fra forskellige raffinaderiprocesser. Den består af carbonhydrider, overvejende C5 til og med C12, med kogeinterval omtrent fra 0 °C til 230 °C (25 ºF til 446 ºF). (da)
C&L Inventory
Fracţia nafta (petrol), nedesulfurat (mt)
C&L Inventory
Fracţia nafta (petrol), nedesulfurat (ro)
C&L Inventory
Fracţia nafta cu punct de fierbere la temperaturi scăzute (mt)
C&L Inventory
Fracţia nafta cu punct de fierbere la temperaturi scăzute (ro)
C&L Inventory
Komplex blandning av kolväten erhållen genom destillation av naftaströmmen från olika raffinaderiprocesser. Består av kolväten, främst C5 till C12, med ungefärligt kokpunktsintervall från 0 °C till 230 °C. (sv)
C&L Inventory
Lavtkogende nafta (da)
C&L Inventory
lavtkokende nafta (no)
C&L Inventory
Ligroīns (nafta), no sēra neattīrīts (lv)
C&L Inventory
Ligroīns ar zemu viršanas temperatūru (lv)
C&L Inventory
Lågkokande nafta (sv)
C&L Inventory
Madala keemispunktiga raskbensiin (et)
C&L Inventory
Matalalla kiehuva teollisuusbensiini (fi)
C&L Inventory
Monimutkainen seos hiilivetyjä, saatu tislaamalla teollisuusbensiinivirtoja useista jalostusprosesseista. Koostuu hiilivedyistä, joiden hiililuvut ovat pääasiassa välillä C5:stä C12:een ja jotka kiehuvat likimäärin välillä 0°C:sta 230°C:een (25°F:sta 446°F:iin). (fi)
C&L Inventory
Nafta (aardolie), niet stankvrij gemaakt (nl)
C&L Inventory
Nafta (petroleum), ej avsvavlad (sv)
C&L Inventory
nafta (petroleum), usøtet (unsweetened) (no)
C&L Inventory
nafta (petrolio), non addolcita (it)
C&L Inventory
Nafta (petróleo), não-adoçada (unsweetened) (pt)
C&L Inventory
nafta (petróleo), sin desazufrar (es)
C&L Inventory
nafta (zemeljsko olje), nesladkana (sl)
C&L Inventory
nafta con basso punto di ebollizione (it)
C&L Inventory
Nafta de baixo ponto de ebulição (pt)
C&L Inventory
nafta de bajo punto de ebullición (es)
C&L Inventory
Nafta met laag kookpunt (nl)
C&L Inventory
nafta z nizko temperaturo vrelišča (sl)
C&L Inventory
naphta (råolie), ikke-sweetenet (da)
C&L Inventory
Naphta non adouci (pétrole); naphta à bas point d'ébullition; [combinaison complexe d'hydrocarbures obtenue par distillation de naphtas résultant de divers procédés de raffinage. Se compose d'hydrocarbures comportant majoritairement entre 5 et 12 atomes de carbone (C5-C12) et dont l'intervalle d'ébullition est compris approximativement entre 0 et 230 oC (entre 25 et 446o F).] (fr)
C&L Inventory
naphta à point d'ébullition bas (fr)
C&L Inventory
Naphtha (Erdöl), ungesüßt (de)
C&L Inventory
Naphtha, niedrigsiedend (de)
C&L Inventory
Nisko-vrijući teški benzin (hr)
C&L Inventory
Niskowrząca frakcja benzynowa (pl)
C&L Inventory
Nízkovroucí benzínová frakce (cs)
C&L Inventory
O combinaţie complexă de hidrocarburi produsă în urma distilării vaporilor fracţiei nafta rezultaţi din diferite procese de rafinare. Constă în hidrocarburi al căror număr de atomi de carbon variază între C5 până la C12 şi are puncte de fierbere cuprinse între aproximativ 0°C şi 230°C (25°F şi 446°F). (mt)
C&L Inventory
Pirminis benzinas (nafta), sieringas (lt)
C&L Inventory
Raskbensiin (nafta), demerkaptaanimata (et)
C&L Inventory
Teollisuusbensiini (maaöljy), makeuttamaton (fi)
C&L Inventory
Złożona mieszanina węglowodorów otrzymywana z destylacji strumieni benzynowych z różnych procesów rafineryjnych. Składa się z węglowodorów o liczbie atomów węgla głównie w zakresie od C5 do C12, wrzących w zakresie temp. od ok. 0°C do 230°C. (pl)
C&L Inventory
ťažký benzín (ropný), nezbavený tiolov (sk)
C&L Inventory
Žematemperatūris pirminis benzinas (lt)
C&L Inventory
Νάφθα χαμηλού σημείου ζέσεως (el)
C&L Inventory
νάφθαΝάφθα (πετρελαίου), μη γλυκασμένη (el)
C&L Inventory
Нискооктанов бензин (нефт), несероочистен (bg)
C&L Inventory
Нискооктанов бензин с ниска температура на кипене (bg)
C&L Inventory
Naphtha (petroleum), unsweetened
Other
Naphtha (petroleum) unsweetened
Registration dossier
Naphtha (petroleum), unsweetened
C&L Inventory, Registration dossier
Naphtha (petroleum), unsweetened
Registration dossier
Naphtha (petroleum), unsweetened / Naphtha (petroleum), unsweetened
Registration dossier
Unsweetened Naphtha
Registration dossier
BENZINETTA LEGGERA
Registration dossier
Export Naphtha
Registration dossier
Feed Naphtha
Registration dossier
FRN
Registration dossier
Full range naphta
Registration dossier
Full range naphtha
Registration dossier
Incorrect naphtha
Registration dossier
MEDIUM STRAIGHT RUN NAPHTHA
Registration dossier
NAFTA UNIVEN
Registration dossier
NAPHTA
Registration dossier
naphtha hydrotreated feed
Registration dossier
Naphtha intermediate
Registration dossier
NAPHTHA, LIGHT STRAIGHT RUN
Registration dossier
NDT feed
Registration dossier
PETROCHEMICAL NAPHTA
Registration dossier
Unsweetened naphtha
Registration dossier
Untreated naphtha
Registration dossier
untreated naphtha (unspecified)
Registration dossier
VIRGN NAFTA ISOMERICA
Registration dossier
649-271-00-2
Index number
C&L Inventory
68783-12-0
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 1 study submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [1]
C Form
Other (100%) [1]
C Substance type
Petroleum product (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Melting/freezing point

Study results
  • 1 study submitted
  • 1 study processed
R Melting / freezing point
-60 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Boiling point

Study results
  • 2 studies submitted
  • 1 study processed
R Boiling point
-20 - 260 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Density

Study results
  • 1 study submitted
  • 1 study processed
R Relative density
0.62 - 0.88 @ 15 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Vapour pressure

Study results
  • 1 study submitted
  • 1 study processed
R Vapour pressure
240 kPa @ 37.8 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Partition coefficient

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Water solubility

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 1 study submitted
  • 1 study processed
R Flash point
-40 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 4 studies submitted
  • 2 studies processed
R Autoflammability / self-ignition
280 - 470 °C @ 101.3 - 101.325 kPa [2]

Type of Study provided
Studies with data
Key study 1 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 1 study submitted
  • 1 study processed
C Interpretation of results
Extremely flammable (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Extremely flammable (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 2 studies submitted
  • 1 study processed
R kinematic viscosity (in mm²/s)
1 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water - screening tests

Study results
  • 7 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 6
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No data available: testing technically not feasible (1)
Intermittent releases (freshwater) No data available: testing technically not feasible (1)
Marine water No data available: testing technically not feasible (1)
Intermittent releases (marine water) No data available: testing technically not feasible (1)
Sewage treatment plant (STP) No data available: testing technically not feasible (1)
Sediment (freshwater) No data available: testing technically not feasible (1)
Sediment (marine water) No data available: testing technically not feasible (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil No data available: testing technically not feasible (1)
Hazard for Predators
Secondary poisoning Insufficient hazard data available (further information necessary) (1)

Short–term toxicity to fish

Study results
  • 16 studies submitted
  • 2 studies processed
P/RResults
LL50 (4 days) 8.2 - 10 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 14
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EL50 (21 days) 10 mg/L [1]
NOELR (21 days) 2.6 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 12 studies submitted
  • 1 study processed
P/RResults
EL50 (48 h) 4.5 mg/L [1]
NOELR (48 h) 500 µg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 11
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 3 studies submitted
  • 1 study processed
P/RResults
NOELR (21 days) 2.6 - 16 mg/L [2]
EL50 (21 days) 10 - 40 mg/L [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 16 studies submitted
  • 1 study processed
P/RResults
EL50 (4 days) 3.7 mg/L [1]
EL50 (72 h) 3.1 mg/L [1]
NOELR (72 h) 500 µg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 15
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
EC50 (40 h) 15.41 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 1.9 mg/m³ repeated dose toxicity
Acute /short term: (DNEL) 1 286.4 mg/m³ neurotoxicity
Local Effects
Long-term: (DNEL) 837.5 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 1 066.67 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: High hazard (no threshold derived)
Acute /short term: High hazard (no threshold derived)
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 410 µg/m³ repeated dose toxicity
Acute /short term: (DNEL) 1 152 mg/m³ neurotoxicity
Local Effects
Long-term: (DNEL) 178.57 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 640 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: High hazard (no threshold derived)
Acute /short term: High hazard (no threshold derived)
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 43 studies submitted
  • 1 study processed
P/RResults
LD50 5 000 mg/kg bw (rat) [1]
M/CInterpretations of results
Not classified [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study 2 40
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 39 studies submitted
  • 1 study processed
M/CInterpretations of results
Not classified [1]

inhalation
Studies with data
Key study 1
Supporting study 38
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 44 studies submitted
  • 1 study processed
P/RResults
LD50 2 000 mg/kg bw (rabbit) [1]
M/CInterpretations of results
Not classified [1]

dermal
Studies with data
Key study 1
Supporting study 43
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed LD50 5 000 mg/kg bw
Inhalation route:
No adverse effect observed LC50 5 610 mg/m³
Dermal route:
No adverse effect observed LD50 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 95 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 3 90
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 45 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study 43
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
Adverse effect observed (irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 43 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 41
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 5 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Study data: oral
Studies with data
Key study 1
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 22 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study 1
Supporting study 21
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 50 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study 1
Supporting study 49
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Inhalation route - systemic effects:
No adverse effect observed NOAEC 1 402 mg/m³ (chronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 22 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 3
Supporting study 18
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: in vivo
  • 14 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 1
Supporting study 13
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Toxicity - InVivo
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 12 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study 2 8
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Inhalation route:
No adverse effect observed NOAEC 9 869 mg/m³ (chronic, rat)

Toxicity to reproduction

Study results
Study data: reproduction
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Study data: developmental
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2
Supporting study 6
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Effect on fertility
Inhalation route:
No adverse effect observed NOAEC 20 000 mg/m³ (chronic, rat)
Effect on developmental toxicity
Dermal route:
No adverse effect observed NOAEL 500 mg/kg bw/day (subchronic, rat)
Inhalation route:
No adverse effect observed NOAEC 23 900 mg/m³ (subchronic, rat)

Neurotoxicity

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant