Brief Profile

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Please be aware that the REACH registration parts of this Brief Profile are no longer maintained; they remain frozen as of 19th May 2023. All other data parts (substance identity, C&L, key regulatory lists etc. are up to date).

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
404-360-3
CAS no.:
119313-12-1
Index number:
606-047-00-9
Molecular formula:
C23H30N2O2
SMILES:
CCC(CC1=CC=CC=C1)(N(C)C)C(=O)C1=CC=C(C=C1)N1CCOCC1
InChI:
InChI=1/C23H30N2O2/c1-4-23(24(2)3,18-19-8-6-5-7-9-19)22(26)20-10-12-21(13-11-20)25-14-16-27-17-15-25/h5-13H,4,14-18H2,1-3H3
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
13
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
ELINCS (European LIst of Notified Chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP14) approved by the European Union, this substance may damage the unborn child, is very toxic to aquatic life and is very toxic to aquatic life with long lasting effects.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance may damage fertility or the unborn child.

Breakdown of all 371 C&L notifications submitted to ECHA

Aquatic Chronic 1 H410 Harmonised Classification
Aquatic Acute 1 H400 Harmonised Classification
Repr. 1B H360D Harmonised Classification
Repr. 2 H361
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

  • R
Officially recognised in the EU as Toxic to Reproduction (Harmonised C&L, Candidate list of SVHCs).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 5 active registrations under REACH, 2 Joint Submission(s) and 6 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Substance of very high concern (SVHC) and included in the candidate list for authorisation.
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Industrial accident prevention and reporting requirements have been established for this substance.
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 tonnes per annum.

This substance is used in articles, by professional workers (widespread uses), in formulation or re-packing and at industrial sites.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles and high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding).

Other release to the environment of this substance is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

This substance can be found in complex articles, with no release intended: machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines) and machinery, mechanical appliances and electrical/electronic products e.g. refrigerators, washing machines, vacuum cleaners, computers, telephones, drills, saws, smoke detectors, thermostats, radiators, large-scale stationary industrial tools). This substance can be found in products with material based on: metal (e.g. cutlery, pots, toys, jewellery), paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper) and plastic (e.g. food packaging and storage, toys, mobile phones).

This substance is used in the following products: coating products, inks and toners, polymers, metals and fillers, putties, plasters, modelling clay.

This substance is used for the manufacture of: .

This substance is used in the following activities or processes at workplace: roller or brushing applications, transfer of chemicals, mixing in open batch processes, non-industrial spraying and treatment of articles by dipping and pouring.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance is used in the following products: coating products, inks and toners, fillers, putties, plasters, modelling clay, polymers and adhesives and sealants.

This substance is used in the following activities or processes at workplace: transfer of chemicals, mixing in open batch processes, closed batch processing in synthesis or formulation, transfer of substance into small containers, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure and laboratory work.

Release to the environment of this substance can occur from industrial use: formulation of mixtures and formulation in materials.

This substance is used in the following products: coating products, inks and toners, fillers, putties, plasters, modelling clay, polymers and adhesives and sealants.

This substance is used in the following areas: formulation of mixtures and/or re-packaging and printing and recorded media reproduction. This substance is used for the manufacture of: wood and wood products, pulp, paper and paper products, plastic products, fabricated metal products, electrical, electronic and optical equipment, machinery and vehicles, furniture and .

This substance is used in the following activities or processes at workplace: transfer of chemicals, roller or brushing applications, industrial spraying, mixing in open batch processes and treatment of articles by dipping and pouring.

Release to the environment of this substance can occur from industrial use: in the production of articles, in processing aids at industrial sites, as processing aid, as processing aid and of substances in closed systems with minimal release.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: obtain special instructions before use; avoid release to the environment; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If exposed or concerned: get medical advice/attention. Collect spillage.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Chemical Inspection & Regulation Service Limited, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • IGM Resins B.V., Gompenstraat 49 5145 RA Waalwijk Netherlands
  • Only representative (No publishable name), null
  • RAHN (3), Hahnstrasse 70 D-60528 Frankfurt am Main Germany
  • ARKEMA FRANCE, 420 rue d'Estienne d'Orves 92700 COLOMBES France
  • BASF Espanola S.L., Calle Can Ràbia, n. 3-5 8017 Barcelona Spain
  • BASF Italia S.p.A., Via Marconato 8 20811 Cesano Maderno Italy
  • BASF Nederland B.V., Velperplein 23 6811 AH Arnhem Netherlands
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • GEELIO Umwelttechnologie GmbH, Hans-Thoma-Strasse 25 D-68163 Mannheim Baden-Württemberg Germany
  • GEELIO Umwelttechnologie GmbH, Langgasse 28 D-55234 Hochborn Rheinland-Pfalz Germany
  • IGM Resins Ltd, c/o Baldwins, Wynyard Park House Wynyard Avenue TS22 5TB Wynyard Durham United Kingdom
  • Only representative (No publishable name), null
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
  • WSP UK Ltd., WSP HOUSE 70 CHANCERY LANE WC2A 1AF LONDON United Kingdom

Substance names and other identifiers

1-Benzyl-1-(dimethylamino)propyl 4-morpholinophenyl ketone
CG 25-369; IRGACURE 369; TK 11-319
Other
1-Butanone, 2-(dimethylamino)-1-(4-(4-morpholinyl)phenyl)-2-(phenylmethyl)-
CG 25-369; IRGACURE 369; TK 11-319
Other
2-Benzyl-2-(dimethylamino)-1-(4-(morpholin-4-yl)phenyl)butan-1-one
CG 25-369; IRGACURE 369; TK 11-319
Other
2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone
EC Inventory, C&L Inventory, Candidate list, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work
2-Benzyl-2-dimethylamino-4'-morpholinobutyrophenone
CG 25-369; IRGACURE 369; TK 11-319
C&L Inventory, Candidate list, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work
2-benzyl-2-dimethylamino-4’-morpholinobutyrophenone
CG 25-369; IRGACURE 369; TK 11-319
REACH pre-registration
2-Bencil-2-dimetilamino-4′-morfolinobutirofenona (es)
C&L Inventory
2-bensyl-2-dimetylamino-4′-morfolinobutyrofenon (sv)
C&L Inventory
2-bensüül-2-dimetüülamino-4'-morfolinobutüülfenoon (et)
C&L Inventory
2-Bentsyyli-2-dimetyyliamino-4'-morfoliinibutyrofenoni (fi)
C&L Inventory
2-benzil-2-dimetilamino-4'-morfolinobutirofenonas (lt)
C&L Inventory
2-benzil-2-dimetilamino-4-morfolinbutirofenon (sl)
C&L Inventory
2-benzil-2-dimetilamino-4’-morfolinobutirofenon (hr)
C&L Inventory
2-benzil-2-dimetilamino-4’-morfolinobutirofenona (pt)
C&L Inventory
2-benzil-2-dimetilamino-4′-morfolinobutirofenon (hu)
C&L Inventory
2-benzil-2-dimetilamino-4′-morfolinobutirofenons (lv)
C&L Inventory
2-benzil-2-dimetilamino-4′-morfolinobutirofenonă (ro)
C&L Inventory
2-benzil-2-dimetilammino-4-morfolinobutirofenone (it)
C&L Inventory
2-benzyl-2-(dimetylamino)-1-(4-morfolinofenyl)bután-1-ón (sk)
C&L Inventory
2-benzyl-2-dimethylamino-1-(4-morfolinofenyl)butan-1-on (cs)
C&L Inventory
2-benzyl-2-dimethylamino-4'-morfolinobutyrofenon (nl)
C&L Inventory
2-benzyl-2-dimethylamino-4'-morpholinobutyrophenon (da)
C&L Inventory
2-Benzyl-2-dimethylamino-4′-morpholinobutyrophenon (de)
C&L Inventory
2-benzyl-2-diméthylamino-4-morpholinobutyrophénone (fr)
C&L Inventory
2-benzylo-2-dimetyloamino-4’-morfolinobutyrofenon (pl)
C&L Inventory
2-benżil-2-dimetilammino-4’-morfolinobutirofenon (mt)
C&L Inventory
2-βενζυλο-2-διμεθυλαμινο-4′-μορφολινοβουτυροφαινόνη (el)
C&L Inventory
2-бензил-2-диметиламино-4′-морфолинобутирофенон (bg)
C&L Inventory
1-Butanone, 2-(dimethylamino)-1-(4-(4-morpholinyl)phenyl)-2-(phenylmethyl)-
C&L Inventory
1-Butanone, 2-(dimethylamino)-1-[4-(4-morpholinyl)phenyl]-2-(phenylmethyl)-
C&L Inventory
2-(dimethylamino)-1-(4-morpholin-4-ylphenyl)-2-(phenylmethyl)butan-1-one
C&L Inventory
2-benzyl-2-(dimethylamino)-1-(4-morpholin-4-ylphenyl)butan-1-one
C&L Inventory
2-benzyl-2-(dimethylamino)-1-[4-(morpholin-4-yl)phenyl]butan-1-one
C&L Inventory, Other
2-Benzyl-2-(dimethylamino)-4'-morpholinobutyrophenone
C&L Inventory
2-Benzyl-2-(dimethylamino)-4-Morpholinobutyrophenone
C&L Inventory
2-benzyl-2-(dimethylamino)1-1(4-morpholin-4-yl)butan-1-one
C&L Inventory
2-Benzyl-2-dimethylamino-4'-morpholinobutyrophenone
C&L Inventory, Registration dossier
2-Benzyl-2-dimethylamino-4'-morpholinobutyrophenone
C&L Inventory, Registration dossier
2-Benzyl-2-dimethylamino-4-morpholinobutyrophenone
C&L Inventory
2-benzyl-2-dimethylamino-4’-morpholinobutyrophenone
C&L Inventory
2-benzyl-2-dimethylamino-4’-morpholinobutyrophenone
C&L Inventory, Registration dossier
2benzyl-2-dimethylamino-4'-morpholinobutyrophenone
C&L Inventory
Genocure BDMM
Registration dossier
Photoinitiator
C&L Inventory
Photoinitiator 369
Registration dossier
PHOTOINITIATOR-369
Registration dossier
2-Benzyl-2-(dimethylaminol-4’ -morpholinobutyrophenone
Registration dossier
CG 25-369
Registration dossier
Chivacure 169
Registration dossier
Genocure BDMM
Registration dossier
IHT-PI 910
Registration dossier
IRGACURE 369
Registration dossier
Omnirad 369
Registration dossier
Speedcure BDMB
Registration dossier
TK 11-319
Registration dossier
119313-12-1
CAS number
C&L Inventory, Candidate list, Registration dossier, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work
136797-29-0
CAS number
Other
1392498-45-1
CAS number
Other
1393715-98-4
CAS number
Other
2102600-95-1
CAS number
Other
606-047-00-9
Index number
C&L Inventory
748160-22-7
CAS number
Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 11 studies submitted
  • 9 studies processed
C Physical state at 20°C and 1013 hPa
Solid (100%) [9]
C Form
Powder (89%), Other (11%) [9]
C Odour
Odourless (75%), Slight (13%), Other (13%) [8]
C Substance type
Organic (100%) [8]

Type of Study provided
Studies with data
Key study 8 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Physical state at 20°C and 1013 hPa
Solid (100%)

Melting/freezing point

Study results
  • 12 studies submitted
  • 11 studies processed
R Melting / freezing point
110 - 115 °C @ 101.3 - 101.325 kPa [11]

Type of Study provided
Studies with data
Key study 10
Supporting study 1
Weight of evidence 1
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Melting / freezing point at 101 325 Pa
113.2 °C

Boiling point

Study results
  • 10 studies submitted
  • 9 studies processed
R Boiling point
185 - 413.8 °C @ 11 - 101 325 Pa [9]

Type of Study provided
Studies with data
Key study 2 7
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 1 summary processed
Boiling point at 101 325 Pa
400 °C

Density

Study results
  • 9 studies submitted
  • 9 studies processed
R Bulk density
1.21 g/cm³ @ 20 °C [1]
R Density
1.21 g/cm³ @ 22 °C [1]
R Relative density
1.21 @ 20 °C [7]

Type of Study provided
Studies with data
Key study 9
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Relative density at 20°C
1.21

Vapour pressure

Study results
  • 9 studies submitted
  • 9 studies processed
R Vapour pressure
0 - 0.01 Pa @ 25 - 95 °C [14]

Type of Study provided
Studies with data
Key study 9
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Vapour pressure
0 - 0.01 Pa @ 25 - 95 °C

Partition coefficient

Study results
  • 9 studies submitted
  • 9 studies processed
R Log Pow
2.91 @ 20 - 25 °C and pH 2 - 8 [9]

Type of Study provided
Studies with data
Key study 9
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Log Kow (Log Pow)
2.91 @ 25 °C

Water solubility

Study results
  • 9 studies submitted
  • 9 studies processed
R Water solubility (mass/vol.)
5.9 mg/L @ 20 °C and pH 6.7 - 7 [9]

Type of Study provided
Studies with data
Key study 9
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Water solubility
5.9 mg/L @ 20 °C

Solubility in organic solvents / fat solubility

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Solubility in mg/100g standard fat at 20 °C
3 240

Surface tension

Study results
  • 9 studies submitted
  • 9 studies processed
R Surface tension
59.1 - 64.7 mN/m @ 6 - 10 000 mg/L and 20 °C [9]

Type of Study provided
Studies with data
Key study 9
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Surface tension at 20 °C
59 - 59.1 mN/m @ 6 - 10 000 mg/L

Flash point

Study results
  • 9 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified 1
Exposure cons.
Other 6
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 9 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 5
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 4
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 11 studies submitted
  • 5 studies processed
C Interpretation of results
Non flammable (100%) [5]

Type of Study provided
Studies with data
Key study 9
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Flammability
Not classified (50%), Non flammable (50%)

Explosiveness

Study results
  • 9 studies submitted
  • 4 studies processed
C Interpretation of results
Non-explosive (100%) [4]

Type of Study provided
Studies with data
Key study 9
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 9 studies submitted
  • 1 study processed
C Interpretation of results
GHS criteria not met (100%) [1]

Type of Study provided
Studies with data
Key study 9
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 1 study processed
C Dissociating properties
Yes (100%) [1]
R Dissociation constant
1.6 - 6.3 @ 25 °C [2]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
pKa at 20 °C
6.3

Viscosity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 5
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 10 studies submitted
  • 9 studies processed
R COD
2.1 g O2/g test material [7]
C Interpretation of results
Under test conditions no biodegradation observed (67%), Not inherently biodegradable (33%) [3]

Type of Study provided
Studies with data
Key study 9
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 1 summary processed
Biodegradation in water
Under test conditions no biodegradation observed (100%)

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Koc at 20°C
48 978

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 4 summaries submitted
  • 4 summaries processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 460 - 500 ng/L (3)
Intermittent releases (freshwater) 4.6 - 5 µg/L (2)
Marine water 46 - 50 ng/L (3)
Intermittent releases (marine water) No hazard identified (1)
Sewage treatment plant (STP) 590 µg/L (2)
Sediment (freshwater) 15 - 490.14 µg/kg sediment dw (3)
Sediment (marine water) 150 - 49 014 ng/kg sediment dw (3)
Hazard for Air
Air No hazard identified (2)
Hazard for Terrestrial Organism
Soil 2.6 - 397.64 µg/kg soil dw (3)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (2)

Short–term toxicity to fish

Study results
  • 5 studies submitted
  • 4 studies processed
P/RResults
LC50 (4 days) 142 - 10 000 µg/L [5]
LC50 (72 h) 460 µg/L [3]
LC50 (48 h) 460 µg/L [3]
LC50 (24 h) 470 µg/L [3]
NOEC (4 days) 300 µg/L [3]

Type of Study provided
Studies with data
Key study 4
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 10 studies submitted
  • 8 studies processed
P/RResults
EC50 (24 h) 800 µg/L [8]
EC0 (24 h) 600 µg/L [1]

Type of Study provided
Studies with data
Key study 8
Supporting study
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (21 days) 210 µg/L [3]
LOEC (21 days) 210 µg/L [3]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 10 studies submitted
  • 9 studies processed
P/RResults
EC50 (4 days) 1 mg/L [1]
EC50 (72 h) 500 - 2 000 µg/L [10]
NOEC (72 h) 500 µg/L [6]

Type of Study provided
Studies with data
Key study 8 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 1 summary processed
EC50 for freshwater algae
500 µg/L
EC10 or NOEC for freshwater algae
500 µg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 4 studies submitted
  • 2 studies processed
P/RResults
EC50 (30 min) 100 mg/L [1]
IC50 (30 min) 5.9 mg/L [1]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
R Summaries
  • 2 summaries submitted
  • 1 summary processed
EC50 for microorganisms
5.9 mg/L
EC10 or NOEC for microorganisms
5.9 mg/L

Sediment toxicity

Data not provided by the registrant

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (14 days) 100 - 1 000 mg/kg soil dw [2]
LOEC (14 days) 1 g/kg soil dw [2]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Data not provided by the registrant

Toxicity to terrestrial plants

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (16 days) 316.2 - 1 000 mg/kg soil dw [3]
NOEC (15 days) 1 g/kg soil dw [12]
NOEC (14 days) 1 g/kg soil dw [3]
NOEC (7 days) 1 g/kg soil dw [6]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Data not provided by the registrant

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 4 summaries submitted
  • 4 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 820 µg/m³ repeated dose toxicity
Acute /short term: (DNEL) 820 µg/m³ repeated dose toxicity
Local Effects
Long-term: Low hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 230 µg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 230 µg/kg bw/day repeated dose toxicity
Local Effects
Long-term: Low hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
EYE Exposure
Low hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 150 µg/m³ repeated dose toxicity
Acute /short term: (DNEL) 150 µg/m³ repeated dose toxicity
Local Effects
Long-term: Low hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 80 µg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 80 µg/kg bw/day repeated dose toxicity
Local Effects
Long-term: Low hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: DNEL
Acute /short term: (DNEL) 80 µg/kg bw/day repeated dose toxicity
EYE Exposure
Low hazard (no threshold derived)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 1 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation potential:
No bioaccumulation potential

Acute toxicity

Study results
oral
  • 10 studies submitted
  • 9 studies processed
P/RResults
LD50 5 000 mg/kg bw (rat) [8]
M/CInterpretations of results
GHS criteria not met [1]

Type of Study provided
oral
Studies with data
Key study 9
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 2
Other 2
dermal
  • 5 studies submitted
  • 5 studies processed
P/RResults
LD50 2 000 mg/kg bw (rat) [2]
M/CInterpretations of results
GHS criteria not met [1]

dermal
Studies with data
Key study 5
Supporting study
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Oral route:
No adverse effect observed Discriminating dose 5 000 mg/kg bw
Dermal route:
No adverse effect observed Discriminating dose 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 10 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 9
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 10 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 9
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 10 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 9
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 9 studies submitted
  • 6 studies processed
P/RResults
NOAEL (rat): 50 - 100 mg/kg bw/day [2]
NOAEL (other:): 50 mg/kg bw/day [4]
LOAEL (rat): 250 - 500 mg/kg bw/day [2]
NOEL (rat): 10 mg/kg bw/day [1]

Type of Study provided
Study data: oral
Studies with data
Key study 6
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: inhalation
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Oral route - systemic effects:
Adverse effect observed NOAEL 100 mg/kg bw/day (subacute, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 18 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 16 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 5
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Data not provided by the registrant

Toxicity to reproduction

Study results
Study data: reproduction
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 2
Other 2
Study data: developmental
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Effect on fertility
Oral route:
No adverse effect observed NOAEL 300 mg/kg bw/day (subchronic, rat)
Effect on developmental toxicity
Oral route:
Adverse effect observed NOAEL 100 mg/kg bw/day (subchronic, rat)

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant