Brief Profile

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

No image available
  • EC / List name:
  • IUPAC name: 1-cyclohexyl-3-[4-({4-[(cyclohexylcarbamoyl)amino]phenyl}methyl)phenyl]urea; 1-cyclohexyl-3-[4-({4-[(octadecylcarbamoyl)amino]phenyl}methyl)phenyl]urea; 3-octadecyl-1-[4-({4-[(octadecylcarbamoyl)amino]phenyl}methyl)phenyl]urea
  • Substance names and other identifiers
EC / List no.:
406-530-2
CAS no.:
-
Index number:
616-070-00-6
Molecular formula:
C117H186N12O6
SMILES:
O=C(NC1CCCCC1)NC1=CC=C(CC2=CC=C(NC(=O)NC3CCCCC3)C=C2)C=C1.CCCCCCCCCCCCCCCCCCNC(=O)NC1=CC=C(CC2=CC=C(NC(=O)NC3CCCCC3)C=C2)C=C1.CCCCCCCCCCCCCCCCCCNC(=O)NC1=CC=C(CC2=CC=C(NC(=O)NCCCCCCCCCCCCCCCCCC)C=C2)C=C1
InChI:
InChI=1S/C51H88N4O2.C39H62N4O2.C27H36N4O2/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-43-52-50(56)54-48-39-35-46(36-40-48)45-47-37-41-49(42-38-47)55-51(57)53-44-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-31-40-38(44)41-36-27-23-33(24-28-36)32-34-25-29-37(30-26-34)43-39(45)42-35-21-18-17-19-22-35;32-26(28-22-7-3-1-4-8-22)30-24-15-11-20(12-16-24)19-21-13-17-25(18-14-21)31-27(33)29-23-9-5-2-6-10-23/h35-42H,3-34,43-45H2,1-2H3,(H2,52,54,56)(H2,53,55,57);23-30,35H,2-22,31-32H2,1H3,(H2,40,41,44)(H2,42,43,45);11-18,22-23H,1-10,19H2,(H2,28,30,32)(H2,29,31,33)
Type of substance:
Multi constituent substance
Origin:
Organic
Registered compositions:
11
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
ELINCS (European LIst of Notified Chemical Substances) List

Hazard classification & labelling

According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance may cause long lasting harmful effects to aquatic life.

Breakdown of all 18 C&L notifications submitted to ECHA

Aquatic Chronic 4 H413 Harmonised Classification
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 9 active registrations under REACH, 2 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: lubricants and greases.

Other release to the environment of this substance is likely to occur from: indoor use as processing aid, outdoor use as processing aid, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles.

Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

This substance is used in the following products: lubricants and greases.

This substance is used for the manufacture of: machinery and vehicles.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, roller or brushing applications, non-industrial spraying, treatment of articles by dipping and pouring, greasing at high energy conditions and heat / pressure transfer fluids in closed systems.

Other release to the environment of this substance is likely to occur from: indoor use as processing aid, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use as processing aid and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

This substance is used in the following products: lubricants and greases.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, mixing in open batch processes, transfer of substance into small containers and laboratory work.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

This substance is used in the following products: lubricants and greases.

This substance is used for the manufacture of: machinery and vehicles.

This substance is used in the following activities or processes at workplace: closed, continuous processes with occasional controlled exposure, transfer of chemicals at dedicated facilities, closed processes with no likelihood of exposure, transfer of substance into small containers, industrial spraying, roller or brushing applications, treatment of articles by dipping and pouring and greasing at high energy conditions.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites and of substances in closed systems with minimal release.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, laboratory work, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure and batch processing in synthesis or formulation with opportunity for exposure.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: avoid release to the environment.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Axel Christiernsson International AB, Strandvägen 10 449 41 Nol Sweden
  • Charles River Laboratories Den Bosch B.V. OR20, Hambakenwetering 7 5231DD 's-Hertogenbosch Netherlands
  • Charles River Laboratories Den Bosch B.V. OR81, Hambakenwetering 7 5231 DD 's-Hertogenbosch Netherlands
  • CS Regulatory Ireland Ltd. in its legal capacity as Only Representative of LANXESS Advanced Material, Alexandra House The Sweepstakes D04 C7H2 Dublin Ballsbridge Ireland
  • FUCHS Lubricants Germany GmbH, Friesenheimer Str. 19 68169 Mannheim Germany
  • IMPERATOR, 340 RUE DE BREUZE BP 59 59780 BAISIEUX France
  • LISAM TELEGIS, Parc d'activités de Noyon-Passel 17 rue de la Couture 60400 PASSEL France
  • Lubricant Consult GmbH, Gutenbergstraße 13 63477 Maintal Hessen Germany
  • Rhenus Lub GmbH & Co KG, Hamburgring 45 D-41179 Mönchengladbach Germany
  • JX Nippon Oil & Energy Europe Limited, 4th Floor, 4 Moorgate EC2R 6DA London United Kingdom

Substance names and other identifiers

3,3'-dioctadecyl-1,1'-methylenebis(4,1-phenylene)diurea
MDI
C&L Inventory
3-cyclohexyl-1-(4-(4-(3-octadecylureido)benzyl)phenyl)urea
MDI
C&L Inventory
A mixture of: 3,3'-dicyclohexyl-1,1'-methylenebis(4,1-phenylene)diurea; 3-cyclohexyl-1-(4-(4-(3-octadecylureido)benzyl)phenyl)urea; 3,3'-dioctadecyl-1,1'-methylenebis(4,1-phenylene)diurea
EC Inventory
A mixture of: 3,3'-dicyclohexyl-1,1'-methylenebis(4,1-phenylene)diurea; 3-cyclohexyl-1-(4-(4-(3-octadecylureido)benzyl)phenyl)urea; 3,3'-dioctadecyl-1,1'-methylenebis(4,1-phenylene)diurea
MDI
REACH pre-registration
reaction mass of: 3,3'-dicyclohexyl-1,1'-methylenebis(4,1-phenylene)diurea
MDI
C&L Inventory
1-cyklohexyl-3-{4-[4-(3-oktadecylureido)benzyl]fenyl}močovina (cs)
C&L Inventory
3,3'-dicikloheksil-1,1'-metilēnbis-(4,1-fenilēn)diurīnvielas, (lv)
C&L Inventory
3,3'-dioctadecil-1,1'-metilen-bis(4,1-fenilen)diureea (ro)
C&L Inventory
3,3'-dioctadecil-1,1'-metilenobis(4,1-fenileno)diurea (es)
C&L Inventory
3,3'-dioctadecil-1,1'-metilenobis(4,1-fenileno)diureia (pt)
C&L Inventory
3,3'-Dioctadecyl-1,1'-(methylenbis(4,1-phenylen))diharnstoff (de)
C&L Inventory
3,3'-dioctadecyl-1,1'-methyleenbis(4,1-fenyleen)diureum (nl)
C&L Inventory
3,3'-dioctadecyl-1,1'-methylenbis(4,1-phenylen)diurinstof (da)
C&L Inventory
3,3'-dioctadécyl-1,1'-méthylènebis(4,1-phénylène)diurée (fr)
C&L Inventory
3,3'-dioktadecil-1,1'-metilenbis(4,1-fenilen)dikarbamido (lt)
C&L Inventory
3,3'-dioktadecil-1,1'-metilenbis(4,1-fenilen)disečnina (sl)
C&L Inventory
3,3'-dioktadecil-1,1'-metilenbis(4,1-fenilen)diuree (hr)
C&L Inventory
3,3'-dioktadecil-1,1'-metilēnbis-(4,1-fenilēn)diurīnvielas maisījums (lv)
C&L Inventory
3,3'-dioktadecyl-1,1'-[methylendi(4,1-fenylen)]dimočovina (cs)
C&L Inventory
3,3'-dioktadecyl-1,1'-metylenbis(4,1-fenylen)diurea (no)
C&L Inventory
3,3'-dioktadecyl-1,1'-metylenbis(4,1-fenylen)diurea (sv)
C&L Inventory
3,3'-dioktadecyl-1,1'-metylénbis(4,1-fenylén)dimočovina (sk)
C&L Inventory
3,3'-dioktadecylo-1,1'-metylenobis(4,1-fenyleno)dimocznik (pl)
C&L Inventory
3,3'-dioktadekyyli-1,1'-metyleenibis(4,1-fenyleeni)diurea (fi)
C&L Inventory
3,3'-dioktadetsüül-1,1'-metüleenbis(4,1-fenüleen)dikarbamiidi segu (et)
C&L Inventory
3,3'-diottadecil-1,1'-metilenebis(4,1-fenilene)diurea (it)
C&L Inventory
3,3'-ditsükloheksüül-1,1'-metüleenbis(4,1-fenüleen)dikarbamiidi, (et)
C&L Inventory
3,3'-διδεκαoκτυλo-1,1'-μεθυλενoδις(4,1-φαινυλενo)διoυρίας (el)
C&L Inventory
3,3'-диоктадецил-1,1 '-метиленбис(4,1-фенилен)диурея (bg)
C&L Inventory
3,3’-diciklohexil-1,1’-metilénbisz(4,1-fenilén)dikarbamid (hu)
C&L Inventory
3,3’-dioktadecil-1,1’-metilénbisz(4,1-fenilén)dikarbamid keveréke (hu)
C&L Inventory
3-cicloesil-1-(4-(4-(3-ottadecilureido)benzil)fenil)urea (it)
C&L Inventory
3-ciclohexil-1-(4-(4-(3-octadecilureido)bencil)fenil)urea (es)
C&L Inventory
3-ciclohexil-1-(4-(4-(3-octadecilureido)benzil)fenil)ureea (ro)
C&L Inventory
3-ciclohexil-1-(4-(4-(3-octadecilureido)benzil)fenil)ureia (pt)
C&L Inventory
3-cikloheksil-1-(4-(4-(3-oktadecilureido)benzil) fenil)urīnvielas un (lv)
C&L Inventory
3-cikloheksil-1-(4-(4-(3-oktadecilureido)benzil)fenil)karbamido (lt)
C&L Inventory
3-cikloheksil-1-{4-[4-(3-oktadecilureido)benzil]fenil}sečnina (sl)
C&L Inventory
3-ciklohexil-1-[4-[4-(3- oktadecilureido)benzil]fenil)karbamid (hu)
C&L Inventory
3-cyclohexyl-1-(4-(4-(3-octadecylureido)benzyl)fenyl)ureum (nl)
C&L Inventory
3-Cyclohexyl-1-(4-(4-(3-octadecylureido)benzyl)phenyl)harnstoff und (de)
C&L Inventory
3-cyclohexyl-1-(4-(4-(3-octadecylureido)benzyl)phenyl)urinstof (da)
C&L Inventory
3-cyclohexyl-1-(4-(4-(3-octadécyluréido)benzyl)phényl)urée (fr)
C&L Inventory
3-cykloheksyl-1-(4-(4-(3-oktadecylureido)benzyl)fenyl)urea (no)
C&L Inventory
3-cykloheksylo-1-{4-[4-(3-oktadecyloureido)benzylo]fenylo}mocznik (pl)
C&L Inventory
3-cyklohexyl-1-(4-(4-(3-oktadecylureido)benzyl)fenyl)urea (sv)
C&L Inventory
3-cyklohexyl-3'-oktadecyl-1,1'-metylénbis(4,1-fenylén)dimočovina (sk)
C&L Inventory
3-sykloheksyyli-1-(4-(4-(3-oktadekyyliureido)bentsyyli)fenyyli)urea (fi)
C&L Inventory
3-tsükloheksüül-1-(4-(4-(3-oktadetsüülureido)bensüül)-fenüül)karbamiidi (et)
C&L Inventory
3-κυκλoεξυλο-1-(4-(4-(3-δεκαoκτυλoυρεϊδo)βενζυλo)φαινυλ)oυρίας (el)
C&L Inventory
3-циклохексил-1-(4-(4-(3-oктадецилуреидо)бензил)фенил)урея (bg)
C&L Inventory
Blanding af: 3,3'-dicyclohexyl-1,1'-methylenbis(4,1-phenylen)diurinstof (da)
C&L Inventory
blanding av: 3,3'-dicykloheksyl-1,1'-metylenbis(4,1-fenylen)diurea (no)
C&L Inventory
Blandning av: 3,3'-dicyklohexyl-1,1'-metylenbis(4,1-fenylen)diurea (sv)
C&L Inventory
masa de reactie a : 3,3'-diciclohexil-1,1'-metilen-bis(4,1-fenilen)diureea (ro)
C&L Inventory
masse de réaction de: 3,3'-dicyclohexyl-1,1'-méthylènebis(4,1-phénylène)diurée;3-cyclohexyl-1-(4-(4-(3-octadécyluréido)benzyl)phényl)urée;3,3'-dioctadécyl-1,1'-méthylènebis(4,1-phénylène)diurée (fr)
C&L Inventory
Mengsel van: 3,3'-dicyclohexyl-1,1'-methyleenbis(4,1-fenyleen)diureum (nl)
C&L Inventory
Mezcla de: 3,3'-diciclohexil-1,1'-metilenobis(4,1-fenileno)diurea (es)
C&L Inventory
mieszanina poreakcyjna 3,3'-dicykloheksylo-1,1'-metylenobis(4,1-fenyleno)dimocznik (pl)
C&L Inventory
Miscela di: 3,3'-dicicloesil-1,1'-metilenebis(4,1-fenilene)diurea (it)
C&L Inventory
Mistura de: 3,3'-diciclohexil-1,1'-metilenobis(4,1-fenileno)diureia (pt)
C&L Inventory
mišinys: 3,3'-dicikloheksil-1,1'-metilenbis(4,1-fenilen)dikarbamido (lt)
C&L Inventory
Mίγμα αντίδρασης: 3,3'-δικυκλoεξυλo-1,1'-μεθυλενoδις(4,1-φαινυλενo)διoυρίας (el)
C&L Inventory
Reaction mass aus: 3,3'-Dicyclohexyl-1,1'-(methylenbis(4,1-phenylen))diharnstoff, (de)
C&L Inventory
reakcijska smjesa: 3,3'-dicikloheksil-1,1'-metilenbis(4,1-fenilen)diuree 3-cikloheksil-1-(4-(4-(3-oktadecilureido)benzil)fenil)uree (hr)
C&L Inventory
reakčná zmes zložená z týchto látok: 3,3'-dicyklohexyl-1,1'-metylénbis(4,1-fenylén)dimočovina (sk)
C&L Inventory
reakční směs: 3,3'-dicyklohexyl-1,1'-[methylendi(4,1-fenylen)]dimočovina (cs)
C&L Inventory
Seos: 3,3'-disykloheksyyli-1,1'-metyleenibis(4,1-fenyleeni)diurea (fi)
C&L Inventory
zmes: 3,3'-dicikloheksil-1,1'-metilenbis(4,1-fenilen)disečnina (sl)
C&L Inventory
реакционна маса от: 3,3'-дициклохексил-1,1'-метиленбис(4,1-фенилен)диурея (bg)
C&L Inventory
A mixture of: 3,3'-dicyclohexyl-1,1'-methylenebis(4,1-phenylene)diurea; 3-cyclohexyl-1-(4-(4-(3-octadecylureido)benzyl)phenyl)urea; 3,3'-dioctadecyl-1,1'-methylenebis(4,1-phenylene)diurea
C&L Inventory
MDI/CHA/ODA
Registration dossier
Reaction mass of 3,3'-dicyclohexyl-1,1'-methylenebis(4,1-phenylene)diurea and 3,3'-dioctadecyl-1,1'-methylenebis(4,1-phenylene)diurea and 3-cyclohexyl-1-(4-(4-(3-octadecylureido)benzyl)phenyl)urea
C&L Inventory
Reaction mass of 3-cyclohexyl-3'-octadecyl-1,1'-methylenebis(4,1-phenylene)diurea and 3,3'-dicyclohexyl-1,1'-methylenebis(4,1-phenylene)diurea and 3,3'-dioctadecyl-1,1'-methylenebis(4,1-phenylene)diurea
Registration dossier
Reaction mass of 3-cyclohexyl-3'-octadecyl-1,1'-methylenebis(4,1-phenylene)diurea; 3,3'-dicyclohexyl-1,1'-methylenebis(4,1-phenylene)diurea and 3,3'-dioctadecyl-1,1'-methylenebis(4,1-phenylene)diurea
Registration dossier
Reaction mass of 3-cyclohexyl-3'-octadecyl-1,1'-methylenebis(4,1-phenylene)diurea; 3,3'-dicyclohexyl-1,1'-methylenebis(4,1-phenylene)diurea and 3,3'-dioctadecyl-1,1'-methylenebis(4,1-phenylene)diurea.
Other
MDI
Registration dossier
MDI/CHA/ODA
Registration dossier
616-070-00-6
Index number
C&L Inventory

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 3 studies submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Solid (100%) [1]
C Form
Powder (100%) [1]
C Odour
Other (100%) [1]
C Substance type
Organic (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Solid (100%)

Melting/freezing point

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Boiling point

Study results
  • 3 studies submitted
  • 1 study processed
R Boiling point
635.85 - 636 °C [2]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
636 °C

Density

Study results
  • 3 studies submitted
  • 1 study processed
R Density
1.107 g/cm³ @ 20 °C [1]
R Relative density
1.107 @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
1.107

Vapour pressure

Study results
  • 4 studies submitted
  • 1 study processed
R Vapour pressure
0 Pa @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 2
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
0 Pa @ 25 °C

Partition coefficient

Study results
  • 7 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other 4
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Water solubility

Study results
  • 4 studies submitted
  • 1 study processed
R Water solubility (mass/vol.)
1 mg/L @ 20 °C and pH 7 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Solubility in organic solvents / fat solubility

Study results
  • 3 studies submitted
  • 1 study processed
R Standard fat
1.6 mg/L @ 37 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Surface tension

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Surface tension at 20 °C
72 mN/m

Flash point

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 2
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Auto flammability

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 7 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 2
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Not classified (100%)

Explosiveness

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other 2
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 2
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Data not provided by the registrant

Viscosity

Data not provided by the registrant

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other 2
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 3 studies submitted
  • 1 study processed
C Interpretation of results
Not readily biodegradable (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Under test conditions no biodegradation observed (100%)
Type of water
Freshwater (100%)

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Data not provided by the registrant

Bioaccumulation: aquatic / sediment

Data not provided by the registrant

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No hazard identified (1)
Intermittent releases (freshwater) No hazard identified (1)
Marine water No hazard identified (1)
Intermittent releases (marine water) No hazard identified (1)
Sewage treatment plant (STP) No hazard identified (1)
Sediment (freshwater) No hazard identified (1)
Sediment (marine water) No hazard identified (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil No hazard identified (1)
Hazard for Predators
Secondary poisoning No potential to cause toxic effects if accumulated (in higher organisms) via the food chain (1)

Short–term toxicity to fish

Study results
  • 3 studies submitted
  • 1 study processed
P/RResults
LC50 (4 days) 1 g/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Data not provided by the registrant

Short–term toxicity to aquatic invertebrates

Study results
  • 3 studies submitted
  • 1 study processed
P/RResults
EC50 (24 h) 1 g/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Data not provided by the registrant

Toxicity to aquatic algae and cyanobacteria

Study results
  • 4 studies submitted
  • 2 studies processed
P/RResults
EC50 (72 h) 100 mg/L [1]
NOEC (72 h) 100 mg/L [1]
EC10 (72 h) 100 mg/L [1]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 4 studies submitted
  • 2 studies processed
P/RResults
EC50 (3 h) 100 - 1 000 mg/L [2]
EC50 (30 min) 100 mg/L [1]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Data not provided by the registrant

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Data not provided by the registrant

Toxicity to terrestrial arthropods

Data not provided by the registrant

Toxicity to terrestrial plants

Data not provided by the registrant

Toxicity to soil microorganisms

Data not provided by the registrant

Toxicity to birds

Data not provided by the registrant

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 2
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Absorption values
Oral: 10 %
Dermal: 10 %
Inhalation: 100 %

Acute toxicity

Study results
oral
  • 3 studies submitted
  • 1 study processed
P/RResults
LD50 2 000 mg/kg bw (rat) [1]
M/CInterpretations of results
GHS criteria not met [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
inhalation
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
dermal
  • 3 studies submitted
  • 1 study processed
P/RResults
LD50 2 000 mg/kg bw (rat) [1]
M/CInterpretations of results
GHS criteria not met [1]

dermal
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed LD50 2 000 mg/kg bw
Dermal route:
No adverse effect observed LD50 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 2
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 2
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 2
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 3 studies submitted
  • 1 study processed
P/RResults
NOEL (rat): 1 000 mg/kg bw/day [1]

Type of Study provided
Study data: oral
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
Study data: inhalation
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route - systemic effects:
No adverse effect observed NOAEL 1 000 mg/kg bw/day (subacute, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 4
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
Study data: in vivo
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Toxicity - InVitro
No adverse effect observed (negative)
Toxicity - InVivo
No adverse effect observed (negative)

Carcinogenicity

Data not provided by the registrant

Toxicity to reproduction

Study results
Study data: reproduction
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: developmental
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Effect on fertility
Oral route:
No adverse effect observed NOAEL 1 000 mg/kg bw/day (subacute, rat)
Effect on developmental toxicity
Oral route:
No adverse effect observed NOAEL 1 000 mg/kg bw/day (subacute, rat)

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant