Brief Profile

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
423-340-5
CAS no.:
162881-26-7
Index number:
015-189-00-5
Molecular formula:
C26H27O3P
SMILES:
CC1=CC(C)=C(C(=O)P(=O)(C(=O)C2=C(C)C=C(C)C=C2C)C2=CC=CC=C2)C(C)=C1
InChI:
InChI=1S/C26H27O3P/c1-16-12-18(3)23(19(4)13-16)25(27)30(29,22-10-8-7-9-11-22)26(28)24-20(5)14-17(2)15-21(24)6/h7-15H,1-6H3
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
15
Of which contain:
5 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
ELINCS (European LIst of Notified Chemical Substances) List

Hazard classification & labelling

Warning! According to the harmonised classification and labelling (ATP14) approved by the European Union, this substance may cause long lasting harmful effects to aquatic life and may cause an allergic skin reaction.

Breakdown of all 424 C&L notifications submitted to ECHA

Aquatic Chronic 4 H413 Harmonised Classification
Skin Sens. 1 H317
Skin Sens. 1A H317 Harmonised Classification
Acute Tox. 4 H302
Eye Dam. 1 H318
Aquatic Chronic 3 H412
Skin Irrit. 2 H315
Not Classified
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://chesar.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

  • Ss
Officially recognised in the EU as Skin sensitising ( Harmonised C&L).
  • Ss
There is broad agreement in that a majority of data submitters agree this substance is Skin sensitising (100% of REACH registrations).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 18 active registrations under REACH, 1 Joint Submission(s) and 4 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 tonnes per annum.

This substance is used in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles, high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding) and transfer of chemicals.

Release to the environment of this substance can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal). Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance can be found in products with material based on: metal (e.g. cutlery, pots, toys, jewellery) and plastic (e.g. food packaging and storage, toys, mobile phones).

This substance is used in the following products: inks and toners, coating products, adhesives and sealants, fillers, putties, plasters, modelling clay, paper chemicals and dyes and polymers.

This substance is used in the following areas: printing and recorded media reproduction. This substance is used for the manufacture of: , wood and wood products, pulp, paper and paper products and chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, roller or brushing applications, mixing in open batch processes, non-industrial spraying, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, treatment of articles by dipping and pouring and the low energy manipulation of substances bound in materials or articles.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance is used in the following products: inks and toners, coating products, polymers, fillers, putties, plasters, modelling clay, adhesives and sealants and paper chemicals and dyes.

This substance is used in the following activities or processes at workplace: transfer of chemicals, transfer of substance into small containers, laboratory work, mixing in open batch processes, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation and closed, continuous processes with occasional controlled exposure.

Release to the environment of this substance can occur from industrial use: formulation of mixtures and formulation in materials.

This substance is used in the following products: coating products, inks and toners, polymers and adhesives and sealants.

This substance is used in the following areas: printing and recorded media reproduction and building & construction work. This substance is used for the manufacture of: wood and wood products, pulp, paper and paper products, fabricated metal products, furniture, rubber products, electrical, electronic and optical equipment and machinery and vehicles.

This substance is used in the following activities or processes at workplace: transfer of chemicals, roller or brushing applications, treatment of articles by dipping and pouring, mixing in open batch processes, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, the low energy manipulation of substances bound in materials or articles, high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding) and industrial spraying.

Release to the environment of this substance can occur from industrial use: in the production of articles, in processing aids at industrial sites and as processing aid.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, transfer of substance into small containers and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: avoid release to the environment; contaminated work clothing should not be allowed out of the workplace; avoid breathing the dust, fume, gas, mist, vapours or spray; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: Take off contaminated clothing and wash it before reuse. Wash contaminated clothing before reuse. If skin irritation or a rash occurs: get medical advice/attention. If on skin: wash with soap and water. Follow specific treatment (see label).

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Agfa-Gevaert N.V., Septestraat 27 2640 Mortsel Belgium
  • ARKEMA FRANCE, 420 rue d'Estienne d'Orves 92700 COLOMBES France
  • BCH Brühl - Chemikalien Handel GmbH, Immendorfer Str. 8 50321 Brühl NRW Germany
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED(Hubei Gurun Technology Co., Ltd.), Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Chemservice S.A. (8LF5), 13, Fausermillen 6689 Mertert Luxembourg
  • COSMO GROUP Sp. z o.o. Sp. k., Jasielska 10a 60-476 Poznań Poland
  • GEELIO Umwelttechnologie GmbH, Langgasse 28 D-55234 Hochborn Rheinland-Pfalz Germany
  • IGM Resins B.V., Gompenstraat 49 5145 RA Waalwijk Netherlands
  • IGM Resins Italia S.r.l, Via Vincenzo Monti, 8 20123 Milano Italy
  • Intercoat Specialties, SL, Verge del Pilar, 6 08750 Molins de Rei Barcelona Spain
  • Nesperta sp. z o.o. , Rejtana 12 A 62-030 Luboń Poland
  • RAHN NL B.V. (30), Westplein 11 3016BM Rotterdam Netherlands
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
  • REACHLINKED OÜ, Ahtri tn 12 10151 Tallinn Estonia
  • GEELIO Umwelttechnologie GmbH, Langgasse 28 D-55234 Hochborn Rheinland-Pfalz Germany
  • IGM Resins Ltd, c/o Baldwins, Wynyard Park House Wynyard Avenue TS22 5TB Wynyard Durham United Kingdom
  • RAHN (3), Hahnstrasse 70 D-60528 Frankfurt am Main Germany
  • WSP UK Ltd., WSP HOUSE 70 CHANCERY LANE WC2A 1AF LONDON United Kingdom

Substance names and other identifiers

BIS(2,4,6-TRIMETHYLBENZOYL)PHENYLPHOSPHINE OXIDE
CGI 819
Other
Bis-trimethylbenzoyl phenylphosphine oxide
CGI 819
Other
Methanone, 1,1'-(phenylphosphinylidene)bis(1-(2,4,6-trimethylphenyl)-
CGI 819
Other
Phenyl bis(2,4,6-trimethylbenzoyl)-phosphine oxide
EC Inventory, C&L Inventory, REACH pre-registration, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
Phenyl bis(2,4,6-trimethylbenzoyl)-phosphine oxide
CGI 819
C&L Inventory, REACH pre-registration, Other, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
Phosphine oxide, phenylbis(2,4,6-trimethylbenzoyl)-
CGI 819
Other
fenil bis(2,4,6-trimetilbenzoil)-fosfina ossido (it)
C&L Inventory
fenil bis(2,4,6-trimetilbenzoil)-fosfino oksidas (lt)
C&L Inventory
fenil bis(2,4,6-trimetilbenzoil)fosfin oksid (sl)
C&L Inventory
fenil-bis(2,4,6-trimetil-benzoil)-fosfin-oksid (hr)
C&L Inventory
fenil-bisz(2,4,6-trimetilbenzoil)-foszfin-oxid (hu)
C&L Inventory
fenilbis(2,4,6-trimetilbenzoil)fosfīnoksīds (lv)
C&L Inventory
fenylbis(2,4,6-trimethylbenzoyl)-fosfineoxide (nl)
C&L Inventory
fenylbis(2,4,6-trimethylbenzoyl)fosfinoxid (cs)
C&L Inventory
fenylbis(2,4,6-trimetylbensoyl)fosfinoxid (sv)
C&L Inventory
fenylbis(2,4,6-trimetylbenzoyl)fosfán-oxid (sk)
C&L Inventory
Fenyylibis (2,4,6-trimetyylibentsoyyli)fosfiinioksidi (fi)
C&L Inventory
fenüülbis(2,4,6-trimetüülbensoüül)fosfiinoksiid (et)
C&L Inventory
ossidu tal-bis(2,4,6-trimetilbenzojl)-fosfina tal-fenil (mt)
C&L Inventory
oxid de bis(2,4,6-trimetilbenzoil)fenilfosfină (ro)
C&L Inventory
oxyde de phényle et de bis(2,4,6-triméthylbenzoyl)-phosphine (fr)
C&L Inventory
phenylbis(2,4,6-trimethylbenzoyl)-phosphinoxid (da)
C&L Inventory
Phenylbis(2,4,6-trimethylbenzoyl)phosphinoxid (de)
C&L Inventory
tlenek fenylobis(2,4,6-trimetylobenzoilo)fosfanu; tlenek fenylobis(2,4,6-trimetylobenzoilo)fosfiny (pl)
C&L Inventory
óxido de fenilbis(2,4,6-trimetilbenzoil) fosfina (pt)
C&L Inventory
Óxido de fenilbis(2,4,6-trimetilbenzoil)fosfina (es)
C&L Inventory
φαινυλο-δις(2,4,6-τριμεθυλοβενζοϋλο)-φωσφινοξείδιο (el)
C&L Inventory
фенилов бис(2,4,6-триметилбензоил)фосфиноксид (bg)
C&L Inventory
[phenyl(2,4,6-trimethylbenzoyl)phosphoryl](2,4,6-trimethylphenyl)methanone
C&L Inventory, Registration dossier, Other
[phenyl-(2,4,6-trimethylbenzoyl)phosohoryl]-(2,4,6-trimethylphenyl),ethanone
C&L Inventory
[Phenyl-(2,4,6-trimethylbenzoyl)phosphoryl]-(2,4,6-trimethylphenyl)methanone
C&L Inventory, Registration dossier, Other
Bis(2,4,6-trimethylbenzoyl) Phenylphosphine Oxide
C&L Inventory
CH03850
Registration dossier
fenil bis(2,4,6-trimetilbenzoil)-fosfina ossido
C&L Inventory
Methanone, 1,1'-(phenylphosphinylidene)bis[1-(2,4,6-trimethylphenyl)-
C&L Inventory
phenyl bis(2,4,6-trimethylbenzoyl)-phosphine oxid
C&L Inventory
Phenyl bis(2,4,6-trimethylbenzoyl)-phosphine oxide
C&L Inventory, Registration dossier
Phenyl bis(2,4,6-trimethylbenzoyl)-phosphine oxide
C&L Inventory, Registration dossier
Phenylbis(2,4,6-trimethylbenzoyl)-phosphine oxide
C&L Inventory
Phenylbis(2,4,6-trimethylbenzoyl)phosphine Oxide
C&L Inventory
Phenylbis(2,4,6-trimethylbenzoyl)phosphine oxide
C&L Inventory, Registration dossier
Phosphine oxide, phenylbis(2,4,6-trimethylbenzoyl)-
C&L Inventory
CGI 819
Registration dossier
Chivacure 789
Registration dossier
GENOCURE* BAPO
Registration dossier
IHT-PI 920
Registration dossier
Irgacure 819
Registration dossier
Omnirad 380
Registration dossier
Omnirad 808
Registration dossier
Omnirad 819
Registration dossier
PI 808
Registration dossier
Speedcure 819
Registration dossier
Speedcure BPO
Registration dossier
015-189-00-5
Index number
C&L Inventory
162881-26-7
CAS number
C&L Inventory, Registration dossier, Other, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
725253-72-5
CAS number
Other
856258-48-5
CAS number
Other
868272-78-0
CAS number
Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 7 studies submitted
  • 7 studies processed
C Physical state at 20°C and 1013 hPa
Solid (100%) [7]
C Form
Powder (71%), Crystalline (29%) [7]
C Odour
Odourless (60%), Other (40%) [5]
C Substance type
Organic (100%) [7]

Type of Study provided
Studies with data
Key study 6 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Physical state at 20°C and 1013 hPa
Solid (100%)

Melting/freezing point

Study results
  • 7 studies submitted
  • 7 studies processed
R Melting / freezing point
127 - 131.4 °C @ 101.3 kPa [7]

Type of Study provided
Studies with data
Key study 7
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Melting / freezing point at 101 325 Pa
127 - 131.4 °C

Boiling point

Study results
  • 7 studies submitted
  • 5 studies processed
R Boiling point
168 °C @ 101.3 kPa [5]

Type of Study provided
Studies with data
Key study 7
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 1 summary processed
Boiling point at 101 325 Pa
168 °C

Density

Study results
  • 7 studies submitted
  • 7 studies processed
R Density
1.19 g/cm³ @ 21 °C [2]
R Relative density
1.19 @ 21 °C [5]

Type of Study provided
Studies with data
Key study 7
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Relative density at 20°C
1.19

Vapour pressure

Study results
  • 7 studies submitted
  • 7 studies processed
R Vapour pressure
0 - 0 Pa @ 20 - 25 °C [13]

Type of Study provided
Studies with data
Key study 7
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 1 summary processed
Vapour pressure
0 Pa @ 20 °C

Partition coefficient

Study results
  • 9 studies submitted
  • 9 studies processed
R Log Pow
4.65 - 5.8 @ 20 - 22 °C and pH 7 - 8.3 [9]

Type of Study provided
Studies with data
Key study 7
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Log Kow (Log Pow)
5.77 - 5.8 @ 22 °C

Water solubility

Study results
  • 7 studies submitted
  • 7 studies processed
R Water solubility (mass/vol.)
100 µg/L @ 20 °C and pH 7.5 [7]

Type of Study provided
Studies with data
Key study 7
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 1 summary processed
Water solubility
100 µg/L @ 21 °C

Solubility in organic solvents / fat solubility

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Surface tension

Study results
  • 7 studies submitted
  • 5 studies processed
R Surface tension
70.7 - 71.4 mN/m @ 100 mg/L and 20 °C [5]

Type of Study provided
Studies with data
Key study 7
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 7 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 3
Sci. unjustified 2
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 7 studies submitted
  • 1 study processed
R Autoflammability / self-ignition
131.4 °C @ 101.3 kPa [1]

Type of Study provided
Studies with data
Key study 7
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 13 studies submitted
  • 7 studies processed
C Interpretation of results
Non flammable (100%) [7]

Type of Study provided
Studies with data
Key study 7
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 6
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Non flammable (100%)

Explosiveness

Study results
  • 7 studies submitted
  • 7 studies processed
C Interpretation of results
Non-explosive (86%), GHS criteria not met (14%) [7]

Type of Study provided
Studies with data
Key study 7
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 7 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 7
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 4
Sci. unjustified
Exposure cons.
Other 3
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 9 studies submitted
  • 4 studies processed
C Interpretation of results
Under test conditions no biodegradation observed (100%) [4]

Type of Study provided
Studies with data
Key study 7
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Biodegradation in water
Under test conditions no biodegradation observed (100%)

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 1 summary processed
Bioaccumulation Factor (BCF) - dimensionless
5

Bioaccumulation: terrestrial

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Adsorption/desorption

Study results
  • 6 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 6
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 1 summary processed
Koc at 20°C
7 079

Henrys law constant (H)

Study results
  • 2 studies submitted
  • 2 studies processed
R H - (pressure) m³/mol
0 Pa m³/mol @ 25 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 4 summaries submitted
  • 4 summaries processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 800 - 1 000 ng/L (4)
Intermittent releases (freshwater) 800 - 1 000 ng/L (4)
Marine water 800 - 1 000 ng/L (4)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 1 mg/L (4)
Sediment (freshwater) 712 µg/kg sediment dw (1)
Sediment (marine water) 712 µg/kg sediment dw (1)
Hazard for Air
Air No hazard identified (4)
Hazard for Terrestrial Organism
Soil 20 mg/kg soil dw (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (4)

Short–term toxicity to fish

Study results
  • 7 studies submitted
  • 5 studies processed
P/RResults
LC50 (4 days) 90 µg/L [5]
LC50 (72 h) 90 µg/L [1]
LC50 (48 h) 90 µg/L [2]
LC50 (24 h) 90 µg/L [2]
LC0 (4 days) 90 µg/L [2]

Type of Study provided
Studies with data
Key study 5
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 7 studies submitted
  • 7 studies processed
P/RResults
EC50 (48 h) 1.175 mg/L [7]
EC50 (24 h) 1.175 mg/L [4]
EC0 (48 h) 3.1 µg/L [2]
EC100 (48 h) 1.175 mg/L [4]
NOEC (48 h) 3.1 µg/L [6]

Type of Study provided
Studies with data
Key study 7
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
NOEC (21 days) 8.1 µg/L [2]
LOEC (21 days) 8.1 µg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 7 studies submitted
  • 7 studies processed
P/RResults
EC50 (72 h) 260 µg/L [14]
NOEC (72 h) 260 µg/L [11]

Type of Study provided
Studies with data
Key study 7
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 1 summary processed
EC50 for freshwater algae
260 µg/L
EC10 or NOEC for freshwater algae
260 µg/L

Toxicity to aquatic plants other than algae

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to microorganisms

Study results
  • 5 studies submitted
  • 5 studies processed
P/RResults
EC50 (3 h) 100 mg/L [3]
IC50 (3 h) 100 mg/L [2]
NOEC (3 h) 100 mg/L [2]

Type of Study provided
Studies with data
Key study 5
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 1 summary processed
EC50 for microorganisms
100 mg/L

Sediment toxicity

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC10 (56 days) 1 g/kg soil dw [2]
LC50 (28 days) 1 g/kg soil dw [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC10 (28 days) 1 g/kg soil dw [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 4 summaries submitted
  • 4 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 7.84 mg/m³ repeated dose toxicity
Acute /short term: (DNEL) 7.84 mg/m³ -
Local Effects
Long-term: Low hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 3 mg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 3.33 mg/kg bw/day -
Local Effects
Long-term: Low hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
EYE Exposure
Low hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 1.93 mg/m³ repeated dose toxicity
Acute /short term: (DNEL) 1.93 mg/m³ -
Local Effects
Long-term: Low hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 1.5 mg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 1.67 mg/kg bw/day -
Local Effects
Long-term: Low hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 1.5 mg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 1.67 ng/kg bw/day -
EYE Exposure
Low hazard (no threshold derived)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Bioaccumulation potential:
No bioaccumulation potential

Acute toxicity

Study results
oral
  • 7 studies submitted
  • 7 studies processed
P/RResults
LD50 2 000 mg/kg bw (rat) [7]
M/CInterpretations of results
Not classified [5]

Type of Study provided
oral
Studies with data
Key study 7
Supporting study
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 5 studies submitted
  • 0 studies processed

No automatically processable data submitted

inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other 4
dermal
  • 6 studies submitted
  • 6 studies processed
P/RResults
LD50 2 000 mg/kg bw (rat) [5]
LD50 2 000 mL/kg bw (rat) [1]
M/CInterpretations of results
Toxicity Category V [1]

dermal
Studies with data
Key study 6
Supporting study
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Oral route:
No adverse effect observed LD50 2 000 mg/kg bw
Dermal route:
No adverse effect observed LD50 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 7
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 6
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin
No adverse effect observed (not irritating)
Eye
Adverse effect observed (irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 10 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 8
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin sensitisation
Adverse effect observed (sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 9 studies submitted
  • 7 studies processed
P/RResults
NOAEL (rat): 1 000 mg/kg bw/day [5]
NOEL (rat): 15 - 300 mg/kg bw/day [4]

Type of Study provided
Study data: oral
Studies with data
Key study 7
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 0 studies submitted
  • 0 studies processed

No data available

Study data: inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 0 studies submitted
  • 0 studies processed

No data available

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oral route - systemic effects:
Adverse effect observed NOAEL 300 mg/kg bw/day (subchronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 19 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 17 1
Supporting study
Weight of evidence 1
Other
Data waiving
no waivers
Study data: in vivo
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other
M/C Summaries
  • 3 summaries submitted
  • 1 summary processed
Toxicity - InVitro
No adverse effect observed (negative)
Toxicity - InVivo
No study available

Carcinogenicity

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 3
Other 2
Study data: developmental
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant