Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

  • EC / List name:
  • IUPAC name: 1,4-dimethyl butanedioate 1,5-dimethyl pentanedioate 1,6-dimethyl hexanedioate 3-carbonoperoxoylpropanoic acid 4-carbonoperoxoylbutanoic acid 4-methoxy-4-oxobutaneperoxoic acid 4-methoxy-4-oxobutanoic acid 5-carbonoperoxoylpentanoic acid 5-methoxy-5-oxopentaneperoxoic acid 5-methoxy-5-oxopentanoic acid 6-methoxy-6-oxohexaneperoxoic acid 6-methoxy-6-oxohexanoic acid butanedioic acid butanediperoxoic acid hexanedioic acid hexanediperoxoic acid methanol pentanedioic acid pentanediperoxoic acid peroxol hydrate
  • Substance names and other identifiers
EC / List no.:
432-790-1
CAS no.:
847871-03-8
Index number:
Molecular formula:
C103H176O88
SMILES:
O.CO.OO.OC(=O)CCC(O)=O.COC(=O)CCC(O)=O.OOC(=O)CCC(O)=O.OC(=O)CCCC(O)=O.COC(=O)CCCC(O)=O.COC(=O)CCC(=O)OC.COC(=O)CCC(=O)OO.OOC(=O)CCCC(O)=O.OOC(=O)CCC(=O)OO.OC(=O)CCCCC(O)=O.COC(=O)CCCCC(O)=O.COC(=O)CCCC(=O)OC.COC(=O)CCCC(=O)OO.OOC(=O)CCCCC(O)=O.OOC(=O)CCCC(=O)OO.COC(=O)CCCCC(=O)OC.COC(=O)CCCCC(=O)OO.OOC(=O)CCCCC(=O)OO
InChI:
InChI=1S/C8H14O4.C7H12O5.2C7H12O4.C6H10O6.2C6H10O5.3C6H10O4.C5H8O6.2C5H8O5.2C5H8O4.C4H6O6.C4H6O5.C4H6O4.CH4O.H2O2.H2O/c1-11-7(9)5-3-4-6-8(10)12-2;1-11-6(8)4-2-3-5-7(9)12-10;1-10-6(8)4-3-5-7(9)11-2;1-11-7(10)5-3-2-4-6(8)9;7-5(11-9)3-1-2-4-6(8)12-10;1-10-5(7)3-2-4-6(8)11-9;7-5(8)3-1-2-4-6(9)11-10;1-9-5(7)3-4-6(8)10-2;1-10-6(9)4-2-3-5(7)8;7-5(8)3-1-2-4-6(9)10;6-4(10-8)2-1-3-5(7)11-9;1-9-4(6)2-3-5(7)10-8;6-4(7)2-1-3-5(8)10-9;1-9-5(8)3-2-4(6)7;6-4(7)2-1-3-5(8)9;5-3(9-7)1-2-4(6)10-8;5-3(6)1-2-4(7)9-8;5-3(6)1-2-4(7)8;2*1-2;/h3-6H2,1-2H3;10H,2-5H2,1H3;3-5H2,1-2H3;2-5H2,1H3,(H,8,9);9-10H,1-4H2;9H,2-4H2,1H3;10H,1-4H2,(H,7,8);3-4H2,1-2H3;2-4H2,1H3,(H,7,8);1-4H2,(H,7,8)(H,9,10);8-9H,1-3H2;8H,2-3H2,1H3;9H,1-3H2,(H,6,7);2-3H2,1H3,(H,6,7);1-3H2,(H,6,7)(H,8,9);7-8H,1-2H2;8H,1-2H2,(H,5,6);1-2H2,(H,5,6)(H,7,8);2H,1H3;1-2H;1H2
Type of substance:
Origin:
Registered compositions:
2
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
ELINCS (European LIst of Notified Chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP05) approved by the European Union, this substance causes severe skin burns and eye damage, is harmful if swallowed, is harmful in contact with skin, is harmful if inhaled and may cause damage to organs.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance causes serious eye damage and if heated may cause a fire.

Breakdown of all 1 C&L notifications submitted to ECHA

Skin Corr. 1B H314 Harmonised Classification
Acute Tox. 4 H302 Harmonised Classification
Acute Tox. 4 H312 Harmonised Classification
Eye Dam. 1 H318
Acute Tox. 4 H332 Harmonised Classification
STOT SE 2 H371 Harmonised Classification
Org. Perox. F H242
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://chesar.echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://chesar.echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://chesar.echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 3 active registrations under REACH, 0 Joint Submission(s) and 1 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 1 000+ tonnes per year.

This substance is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: anti-freeze products, adhesives and sealants, air care products, coating products, lubricants and greases and polishes and waxes.

Other release to the environment of this substance is likely to occur from: outdoor use, indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the types of manufacture using this substance.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, non-industrial spraying, roller or brushing applications and treatment of articles by dipping and pouring.

Other release to the environment of this substance is likely to occur from: outdoor use, indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, transfer of substance into small containers, mixing in open batch processes, production of mixtures or articles by tabletting, compression, extrusion or pelletisation and laboratory work.

Release to the environment of this substance can occur from industrial use: formulation in materials, in processing aids at industrial sites, formulation of mixtures, as processing aid, manufacturing of the substance and for thermoplastic manufacture.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, transfer of substance into small containers and treatment of articles by dipping and pouring.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, formulation in materials, in the production of articles, as processing aid, of substances in closed systems with minimal release, as an intermediate step in further manufacturing of another substance (use of intermediates) and for thermoplastic manufacture. Other release to the environment of this substance is likely to occur from: outdoor use.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, transfer of substance into small containers and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, formulation of mixtures, formulation in materials, in processing aids at industrial sites and as processing aid.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: do not breathe the dust, fume, gas, mist, vapours or spray; keep away from heat, sparks, open flames and/or hot surfaces – No smoking; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing. Immediately call a poison center or doctor/physician.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • RHODIA OPERATIONS, 40 rue de la Haie Coq 93306 AUBERVILLIERS France
  • Solvay Chemie B.V., SCHEPERSWEG 1 6049 HERTEN Netherlands

Substance names and other identifiers

PERESTANE
REACH pre-registration
reaction mass of: succinic acidmonopersuccinic aciddipersuccinic acidmonomethyl ester of succinic acidmonomethyl ester of persuccinic aciddimethyl succinate glutaric acidmonoperglutaric aciddiperglutaric acidmonomethyl ester of glutaric acidmonomethyl ester of perglutaric aciddimethyl glutarate adipic acidmonoperadipic aciddiperadipic acidmonomethyl ester of adipic acidmonomethyl ester of peradipic aciddimethyl adipatehydrogen peroxidemethanolwater
C&L Inventory
acid adipic (ro)
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acid diperadipic (ro)
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acid diperglutaric (ro)
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acid dipersuccinic (ro)
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acid glutaric (ro)
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acid monoperadipic (ro)
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acid monoperglutaric (ro)
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acid monopersuccinic (ro)
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acide adipique (fr)
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acide diperadipique (fr)
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acide diperglutarique (fr)
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acide succinique (fr)
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acide dispersuccinique (fr)
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acide glutarique; acide monoperglutarique (fr)
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acide monoperadipique (fr)
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acide monopersuccinique (fr)
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acido adipico (it)
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acido diperadipico (it)
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acido diperglutarico (it)
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acido dipersuccinico (it)
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acido glutarico (it)
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acido monoperadipico (it)
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acido monoperglutarico (it)
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acido monopersuccinico (it)
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acqua (it)
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adipat de dimetil (ro)
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adipate de diméthyle (fr)
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adipato de dimetilo (es)
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adipato di dimetile (it)
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adipiinhape (et)
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adipiinhappe monometüülester (et)
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adipiinihapon monometyyliesteri (fi)
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adipiinihappo (fi)
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adipinezuur (nl)
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adipinsav (hu)
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adipinsav-monometil-észter (hu)
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adipinska kiselina (hr)
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adipinska kislina (sl)
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adipinsyra, (sv)
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adipinsyre (da)
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Adipinsäure, (de)
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adipo rūgšties (lt)
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adipo rūgšties monometilesterio (lt)
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adipīnskābe (lv)
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adipīnskābes monometilesteris (lv)
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adypinian dimetylu (pl)
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adypinian monometylu (pl)
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agua (es)
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amestec de: acid succinic (ro)
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apă (ro)
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aċidu adipiku (mt)
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aċidu diperadipiku (mt)
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aċidu diperglutariku (mt)
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aċidu dipersuċċiniku (mt)
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aċidu glutariku (mt)
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aċidu monoperadipiku (mt)
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aċidu monoperglutariku (mt)
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aċidu monopersuċċiniku (mt)
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barnsteenzuur (nl)
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Blanding af: (da)
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blanding av: ravsyre (no)
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borostyánkősav (hu)
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borostyánkősav-monometil-észter (hu)
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bursztynian dimetylu (pl)
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bursztynian monometylu (pl)
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dimethyl adipate (mt)
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dimethyl glutarate (mt)
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dimethyl succinate (mt)
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dimethyl-adipát (cs)
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dimethyl-glutarát (cs)
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dimethyladipaat (nl)
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dimethyladipat (da)
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Dimethyladipat, (de)
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dimethylglutaraat (nl)
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dimethylglutarat (da)
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Dimethylglutarat, (de)
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dimethyljantaran (cs)
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dimethylsuccinaat (nl)
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dimethylsuccinat (da)
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Dimethylsuccinat, (de)
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dimetil adipat (hr)
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dimetil glutarat (hr)
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dimetil succinato (it)
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dimetil sukcinat (hr)
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dimetil-adipát (hu)
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dimetil-glutarát (hu)
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dimetil-szukcinát (hu)
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Dimetiladipato (lt)
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dimetiladipāts (lv)
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Dimetilglutarato (lt)
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dimetilglutarāts (lv)
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Dimetilsukcinato (lt)
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dimetilsukcināts (lv)
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dimetyl-adipát (sk)
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dimetyl-glutarát (sk)
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dimetyl-sukcinát (sk)
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dimetyladipat (no)
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dimetyladipat, (sv)
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dimetylbärnstenssyra, (sv)
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dimetylglutarat (no)
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dimetylglutarat, (sv)
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dimetylsuccinat (no)
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dimetyyliadipaatti (fi)
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dimetyyliglutaraatti (fi)
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dimetyylisukkinaatti (fi)
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dimetüüladipinaat (et)
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dimetüülglutaraat (et)
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dimetüülsuktsinaat (et)
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diperadipiinhape (et)
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diperadipiinihappo (fi)
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diperadipinezuur (nl)
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diperadipinsav (hu)
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diperadipinska kiselina (hr)
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diperadipinska kislina (sl)
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diperadipinsyra, (sv)
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diperadipinsyre (no)
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Diperadipinsäure, (de)
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diperadipo rūgšties (lt)
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diperadipīnskābe (lv)
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diperbarnsteenzuur (nl)
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Diperbernsteinsäure, (de)
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diperborostyánkősav (hu)
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diperbärnstenssyra, (sv)
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dipergintaro rūgšties (lt)
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diperglutaarhape (et)
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diperglutaarihappo (fi)
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diperglutaarzuur (nl)
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diperglutarna kiselina (hr)
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diperglutarna kislina (sl)
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diperglutaro rūgšties (lt)
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diperglutarsyra, (sv)
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diperglutarsyre (no)
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Diperglutarsäure, (de)
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diperglutársav (hu)
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diperglutārskābe (lv)
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diperjantarna kislina (sl)
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dipermerevaikhape (et)
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dipermeripihkahappo (fi)
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diperoxyadipinsyre (da)
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diperoxyglutarsyre (da)
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diperoxyravsyre (da)
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diperravsyre (no)
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dipersukcinatna kiselina (hr)
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dipersukcīnskābe (lv)
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eau (fr)
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En blandning av bärnstenssyra, (sv)
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ester monométhylique d'acide adipique (fr)
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ester monométhylique d'acide peradipique (fr)
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ester monométhylique d'acide perglutarique (fr)
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ester monométhylique d'acide persuccinique (fr)
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ester monométhylique d'acide succinique (fr)
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ester monoéthylique d'acide glutarique (fr)
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gintaro rūgšties monometilesterio (lt)
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glutaarhape (et)
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glutaarhappe monometüülester (et)
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glutaarihapon monometyyliesteri (fi)
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Glutaarihappo (fi)
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glutaarzuur (nl)
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glutaran dimetylu (pl)
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glutaran monometylu (pl)
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glutarat de dimetil (ro)
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glutarate de diméthyle (fr)
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glutarato de dimetilo (es)
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glutarato di dimetile (it)
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glutarna kiselina (hr)
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glutarna kislina (sl)
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glutaro rūgšties (lt)
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glutaro rūgšties monometilesterio (lt)
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glutarsyra, (sv)
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glutarsyre (da)
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Glutarsäure, (de)
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glutársav (hu)
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glutársav-monometil-észter (hu)
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glutārskābe (lv)
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glutārskābes monometilesteris (lv)
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hidrogén-peroxid (hu)
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hydrogenperoksid (no)
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hydrogenperoxid (da)
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Hydrogenperoxid, (de)
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ilma (mt)
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Järgmiste komponentide segu: (et)
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kwas adypinowy (pl)
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kwas diperoksobursztynowy (pl)
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kwas diperoksoglutarowy (pl)
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kwas diperoksyadypinowy (pl)
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kwas glutarowy (pl)
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kwas monoperoksobursztynowy (pl)
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kwas monoperoksoglutarowy (pl)
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kwas monoperoksyadypinowy (pl)
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kyselina adipová (cs)
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kyselina diperadipová (cs)
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kyselina diperglutarová (cs)
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kyselina diperjantarová (cs)
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kyselina diperoxyadipová (sk)
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kyselina diperoxyglutárová (sk)
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kyselina diperoxyjantárová (sk)
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kyselina glutarová (cs)
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kyselina glutárová (sk)
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kyselina monoperadipová (cs)
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kyselina monoperglutarová (cs)
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kyselina monoperjantarová (cs)
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kyselina monoperoxyadipová (sk)
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kyselina monoperoxyglutárová (sk)
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kyselina monoperoxyjantárová (sk)
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Maisījums: sukcīnskābe (lv)
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Mengsel van: (nl)
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merevaikhape (et)
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merevaikhappe monometüülester (et)
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meripihkahapon monometyyliesteri (fi)
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metanol (es)
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metanol och (sv)
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metanoli (fi)
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Metanolio (lt)
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metanolo (it)
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metanols (lv)
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metanool (et)
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methanol (cs)
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methanol og (da)
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Methanol und (de)
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metyl-hydrogen-adipát (sk)
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metyl-hydrogen-glutarát (sk)
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metyl-hydrogen-peroxyadipát (sk)
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metyl-hydrogen-peroxyglutarát (sk)
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metyl-hydrogen-peroxysukcinát (sk)
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metyl-hydrogen-sukcinát (sk)
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Mieszanina: kwas bursztynowy (pl)
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mistura de: ácido succínico (pt)
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Mixture of: acido succinico (it)
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mišinys: gintaro rūgšties (lt)
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monemetilestere dell'acido glutarico (it)
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monemetilestere dell'acido peradipico (it)
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monemetilestere dell'acido perglutarico (it)
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monemetilestere dell'acido persuccinico (it)
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monemetilestere dell'acido succinico (it)
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monomethyl ester ta’ l-aċidu adipiku (mt)
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monomethyl ester ta’ l-aċidu glutariku (mt)
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monomethyl ester ta’ l-aċidu peradipiku (mt)
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monomethyl ester ta’ l-aċidu perglutariku (mt)
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monomethyl ester ta’ l-aċidu persuċċiniku (mt)
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monomethyl ester ta’ l-aċidu suċċiniku (mt)
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monomethylester af adipinsyre (da)
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monomethylester af glutarsyre (da)
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monomethylester af peroxyadipinsyre (da)
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monomethylester af peroxyglutarsyre (da)
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monomethylester af peroxyravsyre (da)
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monomethylester af ravsyre (da)
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monomethylester kyseliny adipové (cs)
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monomethylester kyseliny glutarové (cs)
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monomethylester kyseliny jantarové (cs)
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monomethylester kyseliny peradipové (cs)
C&L Inventory
monomethylester kyseliny perglutarové (cs)
C&L Inventory
monomethylester kyseliny perjantarové (cs)
C&L Inventory
monomethylester van adipinezuur (nl)
C&L Inventory
monomethylester van barnsteenzuur (nl)
C&L Inventory
monomethylester van glutaarzuur (nl)
C&L Inventory
monomethylester van peradipinezuur (nl)
C&L Inventory
monomethylester van perbarnsteenzuur (nl)
C&L Inventory
monomethylester van perglutaarzuur (nl)
C&L Inventory
Monomethylester von Adipinsäure, (de)
C&L Inventory
Monomethylester von Bernsteinsäure, (de)
C&L Inventory
Monomethylester von Glutarsäure, (de)
C&L Inventory
Monomethylester von Peradipinsäure, (de)
C&L Inventory
Monomethylester von Perbernsteinsäure, (de)
C&L Inventory
Monomethylester von Perglutarsäure, (de)
C&L Inventory
monometil ester adipinske kiseline (hr)
C&L Inventory
monometil ester glutarne kiseline (hr)
C&L Inventory
monometil ester peradipinske kiseline (hr)
C&L Inventory
monometil ester perglutarne kiseline (hr)
C&L Inventory
monometil ester persukcinatne kiseline (hr)
C&L Inventory
monometil ester sukcinatne kiseline (hr)
C&L Inventory
monometil estra adipinska kislina (sl)
C&L Inventory
monometil estra glutarna kislina (sl)
C&L Inventory
monometil estra jantarna kislina (sl)
C&L Inventory
monometil estra peradipinska kislina (sl)
C&L Inventory
monometil estra perglutarna kislina (sl)
C&L Inventory
monometil estra perjantarna kislina (sl)
C&L Inventory
monometilester al acidului adipic (ro)
C&L Inventory
monometilester al acidului glutaric (ro)
C&L Inventory
monometilester al acidului peradipic (ro)
C&L Inventory
monometilester al acidului perglutaric (ro)
C&L Inventory
monometilester al acidului persuccinic (ro)
C&L Inventory
monometilester al acidului succinic (ro)
C&L Inventory
monometilestere dell'acido adipico (it)
C&L Inventory
monometylester av adipinsyra, (sv)
C&L Inventory
monometylester av adipinsyre (no)
C&L Inventory
monometylester av bärnstenssyra, (sv)
C&L Inventory
monometylester av glutarsyra, (sv)
C&L Inventory
monometylester av glutarsyre (no)
C&L Inventory
monometylester av peradipinsyra, (sv)
C&L Inventory
monometylester av peradipinsyre (no)
C&L Inventory
monometylester av perbärnstenssyra, (sv)
C&L Inventory
monometylester av perglutarsyra, (sv)
C&L Inventory
monometylester av perglutarsyre (no)
C&L Inventory
monometylester av perravsyre (no)
C&L Inventory
monometylester av ravsyre (no)
C&L Inventory
monoperadipiinhape (et)
C&L Inventory
monoperadipiinihappo (fi)
C&L Inventory
monoperadipinezuur (nl)
C&L Inventory
monoperadipinsav (hu)
C&L Inventory
monoperadipinska kiselina (hr)
C&L Inventory
monoperadipinska kislina (sl)
C&L Inventory
monoperadipinsyra, (sv)
C&L Inventory
monoperadipinsyre (no)
C&L Inventory
Monoperadipinsäure, (de)
C&L Inventory
monoperadipo rūgšties (lt)
C&L Inventory
monoperadipīnskābe (lv)
C&L Inventory
monoperbarnsteenzuur (nl)
C&L Inventory
Monoperbernsteinsäure, (de)
C&L Inventory
monoperborostyánkősav (hu)
C&L Inventory
monoperbärnstenssyra, (sv)
C&L Inventory
monopergintaro rūgšties (lt)
C&L Inventory
monoperglutaarhape (et)
C&L Inventory
monoperglutaarihappo (fi)
C&L Inventory
monoperglutaarzuur (nl)
C&L Inventory
monoperglutarna kiselina (hr)
C&L Inventory
monoperglutarna kislina (sl)
C&L Inventory
monoperglutaro rūgšties (lt)
C&L Inventory
monoperglutarsyra, (sv)
C&L Inventory
monoperglutarsyre (no)
C&L Inventory
Monoperglutarsäure, (de)
C&L Inventory
monoperglutársav (hu)
C&L Inventory
monoperglutārskābe (lv)
C&L Inventory
monoperjantarna kislina (sl)
C&L Inventory
monopermerevaikhape (et)
C&L Inventory
monopermeripihkahappo (fi)
C&L Inventory
monoperoksobursztynian monometylu (pl)
C&L Inventory
monoperoxyadipinsyre (da)
C&L Inventory
monoperoxyglutarsyre (da)
C&L Inventory
monoperoxyravsyre (da)
C&L Inventory
monoperravsyre (no)
C&L Inventory
monopersukcinatna kiselina (hr)
C&L Inventory
monopersukcīnskābe (lv)
C&L Inventory
mélange de: (fr)
C&L Inventory
méthanol (fr)
C&L Inventory
nadtlenek wodoru (pl)
C&L Inventory
peradipiinhappe monometüülester (et)
C&L Inventory
peradipiinihapon monometyyliesteri (fi)
C&L Inventory
peradipinsav-monometil-észter (hu)
C&L Inventory
peradipo rūgšties monometilesterio (lt)
C&L Inventory
peradipīnskābes monometilesteris (lv)
C&L Inventory
perborostyánkősav-monometil-észter (hu)
C&L Inventory
pergintaro rūgšties monometilesterio (lt)
C&L Inventory
perglutaarhappe monometüülester (et)
C&L Inventory
perglutaarihapon monometyyliesteri (fi)
C&L Inventory
perglutaro rūgšties monometilesterio (lt)
C&L Inventory
perglutársav-monometil-észter (hu)
C&L Inventory
perglutārskābes monometilesteris (lv)
C&L Inventory
permerevaikhappe monometüülester (et)
C&L Inventory
permeripihkahapon monometyyliesteri (fi)
C&L Inventory
peroksoadypinian monometylu (pl)
C&L Inventory
peroksoglutaran monometylu (pl)
C&L Inventory
perossido di idrogeno (it)
C&L Inventory
perossidu ta’ l-idroġenu (mt)
C&L Inventory
peroxid de hidrogen (ro)
C&L Inventory
peroxid vodíka (sk)
C&L Inventory
peroxid vodíku (cs)
C&L Inventory
peroxyde d'hydrogène (fr)
C&L Inventory
persukcīnskābes monometilesteris (lv)
C&L Inventory
peróxido de hidrogénio (pt)
C&L Inventory
peróxido de hidrógeno (es)
C&L Inventory
ravsyre (da)
C&L Inventory
Reaction mass aus Bernsteinsäure (de)
C&L Inventory
reakcijska smjesa: (hr)
C&L Inventory
reakčná zmes zložená z týchto látok: kyselina jantárová (sk)
C&L Inventory
reakční směs: kyselina jantarová (butandiová) (cs)
C&L Inventory
Seos: meripihkahappo (fi)
C&L Inventory
succinat de dimetil (ro)
C&L Inventory
succinate de diméthyle (fr)
C&L Inventory
succinato de dimetilo (es)
C&L Inventory
sukcinatna kiselina (hr)
C&L Inventory
sukcīnskābes monometilesteris (lv)
C&L Inventory
Taħlita ta’: aċidu suċċiniku (mt)
C&L Inventory
vand (da)
C&L Inventory
vandenilio peroksido (lt)
C&L Inventory
vandens (lt)
C&L Inventory
vann (no)
C&L Inventory
vatten (sv)
C&L Inventory
vesi (et)
C&L Inventory
vesinikperoksiid (et)
C&L Inventory
vetyperoksidi (fi)
C&L Inventory
voda (cs)
C&L Inventory
vodikov peroksid (hr)
C&L Inventory
väteperoxid, (sv)
C&L Inventory
víz keveréke (hu)
C&L Inventory
Wasser (de)
C&L Inventory
water (nl)
C&L Inventory
waterstofperoxide (nl)
C&L Inventory
woda (pl)
C&L Inventory
zmes: jantarna kislina (sl)
C&L Inventory
ácido adípico (es)
C&L Inventory
ácido diperadípico (es)
C&L Inventory
ácido diperglutárico (es)
C&L Inventory
ácido dipersuccínico (es)
C&L Inventory
ácido glutárico (es)
C&L Inventory
ácido monoperadípico (es)
C&L Inventory
ácido monoperglutárico (es)
C&L Inventory
ácido monopersuccínico (es)
C&L Inventory
ácido succínico (es)
C&L Inventory
água (pt)
C&L Inventory
éster monometílico del ácido adípico (es)
C&L Inventory
éster monometílico del ácido glutárico (es)
C&L Inventory
éster monometílico del ácido peradípico (es)
C&L Inventory
éster monometílico del ácido perglutárico (es)
C&L Inventory
éster monometílico del ácido persuccínico (es)
C&L Inventory
éster monometílico del ácido succínico (es)
C&L Inventory
éster monometílico do ácido adípico (pt)
C&L Inventory
éster monometílico do ácido glutárico (pt)
C&L Inventory
éster monometílico do ácido peradípico (pt)
C&L Inventory
éster monometílico do ácido perglutárico (pt)
C&L Inventory
éster monometílico do ácido persuccínico (pt)
C&L Inventory
éster monometílico do ácido succínico (pt)
C&L Inventory
ūdens (lv)
C&L Inventory
ūdeņraža peroksīds (lv)
C&L Inventory
αδιπικό διμεθύλιο (el)
C&L Inventory
αδιπικό οξύ (el)
C&L Inventory
γλουταρικό διμεθύλιο (el)
C&L Inventory
γλουταρικό οξύ (el)
C&L Inventory
διυπεραδιπικό οξύ (el)
C&L Inventory
διυπεργλουταρικό οξύ (el)
C&L Inventory
διυπερηλεκτρικό οξύ (el)
C&L Inventory
ηλεκτρικό διμεθύλιο (el)
C&L Inventory
Μείγμα από: ηλεκτρικό οξύ (el)
C&L Inventory
μεθανόλη και (el)
C&L Inventory
μονομεθυλεστέρα του αδιπικού οξέος (el)
C&L Inventory
μονομεθυλεστέρα του γλουταρικού οξέος (el)
C&L Inventory
μονομεθυλεστέρα του ηλεκτρικού οξέος (el)
C&L Inventory
μονομεθυλεστέρα του υπεραδιπικού οξέος (el)
C&L Inventory
μονομεθυλεστέρα του υπεργλουταρικού οξέος (el)
C&L Inventory
μονομεθυλεστέρα του υπερηλεκτρικού οξέος (el)
C&L Inventory
νερό (el)
C&L Inventory
υπεραδιπικό οξύ (el)
C&L Inventory
υπεργλουταρικό οξύ (el)
C&L Inventory
υπερηλεκτρικό οξύ (el)
C&L Inventory
υπεροξείδιο του υδρογόνου (el)
C&L Inventory
адипинова киселина (bg)
C&L Inventory
вода (bg)
C&L Inventory
водороден пероксид (bg)
C&L Inventory
глутарова киселина (bg)
C&L Inventory
диметил адипат (bg)
C&L Inventory
диметил глутарат (bg)
C&L Inventory
диметилов сукцинат (bg)
C&L Inventory
диперадипинова киселина (bg)
C&L Inventory
диперглутарова киселина (bg)
C&L Inventory
диперянтарна киселина (bg)
C&L Inventory
метанол (bg)
C&L Inventory
монометилов естер на адипинова киселина (bg)
C&L Inventory
монометилов естер на глутарова киселина (bg)
C&L Inventory
монометилов естер на перадипинова киселина (bg)
C&L Inventory
монометилов естер на перглутарова киселина (bg)
C&L Inventory
монометилов естер на перянтарна киселина (bg)
C&L Inventory
монометилов естер на янтарна киселина (bg)
C&L Inventory
моноперадипинова киселина (bg)
C&L Inventory
моноперглутарова киселина (bg)
C&L Inventory
моноперянтарна киселина (bg)
C&L Inventory
реакционна маса от: янтарна киселина (bg)
C&L Inventory
1,4-dimethyl butanedioate 1,5-dimethyl pentanedioate 1,6-dimethyl hexanedioate 3-carbonoperoxoylpropanoic acid 4-carbonoperoxoylbutanoic acid 4-methoxy-4-oxobutaneperoxoic acid 4-methoxy-4-oxobutanoic acid 5-carbonoperoxoylpentanoic acid 5-methoxy-5-oxopentaneperoxoic acid 5-methoxy-5-oxopentanoic acid 6-methoxy-6-oxohexaneperoxoic acid 6-methoxy-6-oxohexanoic acid butanedioic acid butanediperoxoic acid hexanedioic acid hexanediperoxoic acid methanol pentanedioic acid pentanediperoxoic acid peroxol hydrate
Other
Perestane ®
Registration dossier
reaction mass of: succinic acid, monopersuccinic acid, dipersuccinic acid, monomethyl ester of succinic acid, monomethyl ester of persuccinic acid, dimethyl succinate, glutaric acid, monoperglutaric acid, diperglutaric acid, monomethyl ester of glutaric acid, monomethyl ester of perglutaric acid, dimethyl glutarate, adipic acid, monoperadipic acid, diperadipic acid, monomethyl ester of adipic acid, monomethyl ester of peradipic acid, dimethyl adipate, hydrogen peroxide, methanol, water
Registration dossier
PERESTANE®
Registration dossier
607-613-00-8
Index number
C&L Inventory
847871-03-8
CAS number
Registration dossier

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [1]
C Substance type
Organic (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Melting/freezing point

Study results
  • 2 studies submitted
  • 1 study processed
R Melting / freezing point
-75 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Boiling point

Study results
  • 2 studies submitted
  • 1 study processed
R Boiling point
215.6 °C @ 101.3 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Density

Study results
  • 2 studies submitted
  • 1 study processed
R Relative density
1.06 @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
1.055

Vapour pressure

Study results
  • 2 studies submitted
  • 1 study processed
R Vapour pressure
1.3 - 11 Pa @ 5 - 25 °C [5]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
10 Pa @ 25 °C

Partition coefficient

Study results
  • 3 studies submitted
  • 1 study processed
R Log Pow
0.89 @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
0.89 @ 25 °C

Water solubility

Study results
  • 2 studies submitted
  • 1 study processed
R Water solubility (mass/vol.)
25.2 g/L @ 20 °C and pH 4.5 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
25.2 g/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 2 studies submitted
  • 1 study processed
R Flash point
98.5 °C @ 101.1 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 2 studies submitted
  • 1 study processed
R Autoflammability / self-ignition
430 °C @ 101.1 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Explosiveness

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Viscosity

Study results
  • 1 study submitted
  • 1 study processed
R dynamic viscosity (in mPa s)
2.846 - 2.854 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Dynamic viscosity at 20 °C
2.85 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 2 studies submitted
  • 1 study processed
C Interpretation of results
Readily biodegradable (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Readily biodegradable (100%)

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 123 µg/L (1)
Intermittent releases (freshwater) 1.23 mg/L (1)
Marine water 12.3 µg/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 100 mg/L (1)
Sediment (freshwater) 660 µg/kg sediment dw (1)
Sediment (marine water) 66 µg/kg sediment dw (1)
Hazard for Air
Air -
Hazard for Terrestrial Organism
Soil 61 µg/kg soil dw (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 3 studies submitted
  • 1 study processed
P/RResults
LC50 (4 days) 56 mg/L [1]
LC100 (4 days) 100 mg/L [1]
NOEC (4 days) 22 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
LC50 for freshwater fish
56 mg/L

Long–term toxicity to fish

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (28 days) 2.5 mg/L [1]
LOEC (28 days) 2.5 mg/L [1]
EC50 (28 days) 2.5 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EC50 (48 h) 100 mg/L [1]
NOEC (48 h) 100 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to aquatic algae and cyanobacteria

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
NOEC (72 h) 100 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EC50 (3 h) 1 g/L [1]
NOEC (3 h) 1 g/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: (DNEL) 6.7 mg/m³ repeated dose toxicity
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: Hazard unknown (no further information necessary)
Acute /short term: No hazard identified
Local Effects
Long-term: Hazard unknown (no further information necessary)
Acute /short term: No hazard identified
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: (DNEL) 4 mg/m³ repeated dose toxicity
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: Hazard unknown (no further information necessary)
Acute /short term: No hazard identified
Local Effects
Long-term: Hazard unknown (no further information necessary)
Acute /short term: Hazard unknown (no further information necessary)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: dermal absorption
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Absorption values
Dermal: 3 %

Acute toxicity

Study results
oral
  • 2 studies submitted
  • 1 study processed
P/RResults
LD50 2 000 mg/kg bw (rat) [1]
M/CInterpretations of results
Not classified [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
inhalation
  • 1 study submitted
  • 1 study processed
P/RResults
LC50 (4 h) 5.6 mg/L air (rat) [1]
M/CInterpretations of results
Not classified [1]

inhalation
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 2 studies submitted
  • 1 study processed
P/RResults
LD50 2 000 mg/kg bw (rat) [1]
M/CInterpretations of results
Not classified [1]

dermal
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed Discriminating dose 2 000 mg/kg bw
Inhalation route:
No adverse effect observed Discriminating conc. 5.6 mg/m³
Dermal route:
No adverse effect observed Discriminating dose 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Study data: eye
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No adverse effect observed (not irritating)

Sensitisation

Study results
Study data: skin
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 2 studies submitted
  • 1 study processed
P/RResults
NOAEL (rat): 300 mg/kg bw/day [1]

Type of Study provided
Study data: oral
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Study data: inhalation
  • 1 study submitted
  • 1 study processed
P/RResults
NOAEC (rat): 40 mg/m³ air [1]

Study data: inhalation
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route - systemic effects:
Adverse effect observed NOAEL 300 mg/kg bw/day (subacute, rat)
Inhalation route - systemic effects:
No adverse effect observed NOAEC 5 000 mg/m³ (subchronic, rat)
Inhalation route - local effects:
Adverse effect observed NOAEC 40 mg/m³ (subchronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 2
Supporting study
Weight of evidence
Other 3
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: in vivo
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: developmental
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Effect on fertility
Oral route:
No adverse effect observed NOAEL 1 000 mg/kg bw/day (subacute, rat)
Effect on developmental toxicity
Oral route:
Adverse effect observed NOAEL 300 mg/kg bw/day (subacute, rabbit)

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant