cosmetics-prohibited-subs

cosmetics-prohibited-subs

Cosmetic Products Regulation, Annex II - Prohibited Substances

EU. Prohibited Substances: Annex II, Regulation 1223/2009/EC on Cosmetic Products, as amended by Regulation (EU) 2023/1490, OJ L 183, 20 July 2023

This list contains substances which are banned from use in any cosmetic products marketed for sale or use in the European Union.

Last updated 19 April 2024. Database contains 2528 unique substances/entries.

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Showing 2,001 - 2,200 of 2,528 results.

Substance Name	EC No.	CAS No.	Ref No.	Product type, body parts	Maximum Threshold	Restriction(s)
Acetamide	200-473-5	60-35-5	1076	All cosmetic products	0 %		Details
Methylhydrazine	200-471-4	60-34-4	1608	All cosmetic products	0 %		Details
Aminocaproic acid	200-469-3	60-32-2	7	All cosmetic products	0 %		Details
4-Aminoazobenzene	200-453-6	60-09-3	990	All cosmetic products	0 %		Details
Isocarboxazid	200-438-4	59-63-2	52	All cosmetic products	0 %		Details
Mephenesin	200-427-4	59-47-2	322	All cosmetic products	0 %		Details
2-[4-Methoxybenzyl-N-(2-pyridyl)amino]ethyldimethylamine maleate	200-422-7	59-33-6	346	All cosmetic products	0 %		Details
Methotrexate	200-413-8	59-05-2	6	All cosmetic products	0 %		Details
1,2,3,4,5,6-Hexachlorocyclohexane	200-401-2	58-89-9	195	All cosmetic products	0 %		Details
Diphenhydramine	200-396-7	58-73-1	339	All cosmetic products	0 %		Details
Theophylline	200-385-7	58-55-9	1710	All cosmetic products	0 %		Details
Tetrabenazine	200-383-6	58-46-8	139	All cosmetic products	0 %		Details
(R) 5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol	200-360-0	58-00-4	42	All cosmetic products	0 %		Details
Sulfinpyrazone	200-357-4	57-96-5	155	All cosmetic products	0 %		Details
Chlordane, pur	200-349-0	57-74-9	1073	All cosmetic products	0 %		Details
Probenecid	200-344-3	57-66-9	161	All cosmetic products	0 %		Details
Propiolactone	200-340-1	57-57-8	669	All cosmetic products	0 %		Details
Meprobamate	200-337-5	57-53-4	236	All cosmetic products	0 %		Details
Eserine	200-332-8	57-47-6	166	All cosmetic products	0 %		Details
Strychnine	200-319-7	57-24-9	304	All cosmetic products	0 %		Details
Allyl isothiocyanate	200-309-2	57-06-7	18	All cosmetic products	0 %		Details
Benz[a]anthracene	200-280-6	56-55-3	638	All cosmetic products	0 %		Details
O,O'-Diethyl-O-4-nitrophenyl phosphorothioate	200-271-7	56-38-2	131	All cosmetic products	0 %		Details
Cantharidine	200-263-3	56-25-7	70	All cosmetic products	0 %		Details
Carbon tetrachloride	200-262-8	56-23-5	315	All cosmetic products	0 %		Details
Hexamethonium bromide	200-249-7	55-97-0	124	All cosmetic products	0 %		Details
Guanethidine	200-241-3	55-65-2	259	All cosmetic products	0 %		Details
Propane-1,2,3-triyl trinitrate	200-240-8	55-63-0	253	All cosmetic products	0 %		Details
Fenthion	200-231-9	55-38-9	1072	All cosmetic products	0 %		Details
Isoniazid	200-214-6	54-85-3	200	All cosmetic products	0 %		Details
Metyrapone	200-206-2	54-36-4	292	All cosmetic products	0 %		Details
Nicotine	200-193-3	54-11-5	246	All cosmetic products	0 %		Details
3,4,5-Trimethoxyphenethylamine	200-190-7	54-04-6	222	All cosmetic products	0 %		Details
Dibenz[a,h]anthracene	200-181-8	53-70-3	637	All cosmetic products	0 %		Details
Paramethasone	200-169-2	53-33-8	186	All cosmetic products	0 %		Details
Haloperidol	200-155-6	52-86-8	185	All cosmetic products	0 %		Details
Thiotepa	200-135-7	52-24-4	310	All cosmetic products	0 %		Details
Spironolactone	200-133-6	52-01-7	4	All cosmetic products	0 %		Details
(2-Acetoxyethyl)trimethylammonium hydroxide	200-128-9	51-84-3	2	All cosmetic products	0 %		Details
Urethane	200-123-1	51-79-6	671	All cosmetic products	0 %		Details
Chlormethine	200-120-5	51-75-2	87	All cosmetic products	0 %		Details
Atropine	200-104-8	51-55-8	45	All cosmetic products	0 %		Details
Epinephrine	200-098-7	51-43-4	14	All cosmetic products	0 %		Details
Noradrenaline	200-096-6	51-41-2	257	All cosmetic products	0 %		Details
Hyoscine	200-090-3	51-34-3	295	All cosmetic products	0 %		Details
2,4-Dinitrophenol	200-087-7	51-28-5	151	All cosmetic products	0 %		Details
Tiratricol	200-086-1	51-24-1	5	All cosmetic products	0 %		Details
Fluorouracil	200-085-6	51-21-8	190	All cosmetic products	0 %		Details
Tretamine	200-083-5	51-18-3	328	All cosmetic products	0 %		Details
Procainamide	200-078-8	51-06-9	25	All cosmetic products	0 %		Details
Amitriptyline	200-041-6	50-48-6	146	All cosmetic products	0 %		Details
Lysergide	200-033-2	50-37-3	127	All cosmetic products	0 %		Details
Thalidomide	200-031-1	50-35-1	280	All cosmetic products	0 %		Details
Phenylbutazone	200-029-0	50-33-9	67	All cosmetic products	0 %		Details
Benzo[def]chrysene	200-028-5	50-32-8	612	All cosmetic products	0 %		Details
Clofenotane	200-024-3	50-29-3	123	All cosmetic products	0 %		Details
Cyclophosphamide	200-015-4	50-18-0	88	All cosmetic products	0 %		Details
Ergocalciferol	200-014-9	50-14-6	335	All cosmetic products	0 %		Details
Formaldehyde	200-001-8	50-00-0	1577	All cosmetic products	0 %		Details
Zirconium and its compounds, with the exception of the substances listed under reference number 50 in Annex III, and the zirconium lakes, pigments or salts of the colouring agents when listed in Annex IV	-	-	391	All cosmetic products	0 %	Not permitted except for the substances listed under reference number 50 in Annex III, and the zirconium lakes, pigments, or salts of the colouring agents when listed in Annex IV	Details
Xanthylium, 9-(2-carboxyphenyl)-3-((2-methylphenyl)amino)-6-((2-methyl-4-sulfophenyl)amino)-, inner salt	-	10213-95-3	1335	Hair dye products	0 %		Details
Verbena essential oils derivatives other than absolute	-	-	450	Fragrance ingredient	0 %		Details
Vaccines, toxins or serums defined as immunological medicinal products pursuant to Article 1 of Directive 2001/83/EC	-	-	323	All cosmetic products	0 %	For the individual ingredient see reference number 364 in Annex II.	Details
Triticonazole (ISO)	-	138182-18-0	1693	All cosmetic products	0 %		Details
Trisodium bis(7-acetamido-2-(4-nitro-2-oxidophenylazo)-3-sulfonato-1-naphtholato)chromate(1-)	-	148262-86-6	1131	All cosmetic products	0 %		Details
Trioctyldodecyl borate	-	-	1396	All cosmetic products	0 %		Details
Trinickel tetrasulfide	-	12137-12-1	1447	All cosmetic products	0 %		Details
Trinickel bis(arsenite)	-	74646-29-0	1448	All cosmetic products	0 %		Details
Trifluperidol	-	749-13-3	188	All cosmetic products	0 %		Details
Trichlormethine	-	555-77-1	327	All cosmetic products	0 %		Details
Tributyltin compounds	-	-	1581	All cosmetic products	0 %		Details
Tolboxane	-	2430-46-8	177	All cosmetic products	0 %		Details
Thyropropic acid	-	51-26-3	9	All cosmetic products	0 %		Details
Thallium and its compounds	-	-	317	All cosmetic products	0 %		Details
Tetrahydro-6-nitroquinoxaline and its salts;Tetrahydro-6-nitroquinoxaline hydrochloride	-	158006-54-3	1240	All cosmetic products	0 %		Details
Tetrahydro-6-nitroquinoxaline and its salts;Tetrahydro-6-nitroquinoxaline hydrochloride	-	158006-54-3	1240	All cosmetic products	0 %		Details
Tetrachlorosalicylanilides	-	7426-07-5	348	All cosmetic products	0 %		Details
Tetrabromosalicylanilides	-	-	350	All cosmetic products	0 %		Details
Tetraborates	-	-	1396	All cosmetic products	0 %		Details
Tellurium and its compounds	-	-	312	All cosmetic products	0 %		Details
Tefazoline	-	1082-56-0	237	All cosmetic products	0 %		Details
Technical product-reaction mass of [4-methyl-m-phenylenediamine and 2-methyl-m-phenylenediamine]	-	-	1507	All cosmetic products	0 %		Details
Synthetic curarizants	-	-	110	All cosmetic products	0 %		Details
Sulphonamides (sulphanilamide and its derivatives obtained by substitution of one or more H-atoms of the -NH2 groups) and their salts	-	-	307	All cosmetic products	0 %		Details
Substances with androgenic effect	-	-	37	All cosmetic products All cosmetic products	0 %		Details
Strychnos species and their galenical preparations	-	-	305	All cosmetic products	0 %		Details
Strophantus species and their galenical preparations	-	-	303	All cosmetic products	0 %		Details
Strophanthins	-	-	302	All cosmetic products	0 %		Details
Strontium polycarboxylate	-	-	404	All cosmetic products	0 %		Details
Sodium salt or Salts of Isopropylparaben	-	-	1374	All cosmetic products	0 %		Details
Sodium peroxoborate hexahydrate	-	-	1398	All cosmetic products	0 %		Details
Sodium nonadecafluorodecanoate	-	3830-45-3	1604	All cosmetic products	0 %		Details
Sodium hexacyclonate	-	7009-49-6	114	All cosmetic products	0 %		Details
Silicon carbide, fibrous	-	308076-74-6	1658	All cosmetic products	0 %	Not permitted if fibers with diameter < 3 μm, length > 5 μm and aspect ratio ≥ 3:1	Details
Silicic acid, lead nickel salt	-	68130-19-8	1456	All cosmetic products	0 %		Details
Selenium and its compounds with the exception of selenium disulphide under the conditions set out under reference No 49 in Annex III	-	-	297	All cosmetic products	0 %	Not permitted except for selenium disulphide under the conditions set out under reference no. 49 in Annex III	Details
Secondary alkylamines	-	-	411	All cosmetic products	0 %		Details
Secondary alkanolamines	-	-	411	All cosmetic products	0 %		Details
Salts of yohimbine	-	-	337	All cosmetic products	0 %		Details
Salts of xylometazoline	-	-	313	All cosmetic products	0 %		Details
Salts of xylidines	-	-	33	All cosmetic products	0 %		Details
Salts of warfarin	-	-	203	All cosmetic products	0 %		Details
Salts of veratrine	-	-	331	All cosmetic products	0 %		Details
Salts of tuaminoheptane	-	-	27	All cosmetic products	0 %		Details
Salts of trichlormethine	-	-	327	All cosmetic products	0 %		Details
Salts of triamterene	-	-	275	All cosmetic products	0 %		Details
Salts of tretinoin	-	-	375	All cosmetic products	0 %		Details
Salts of tranylcypromine	-	-	324	All cosmetic products	0 %		Details
Salts of toluidines	-	-	32	All cosmetic products	0 %		Details
Salts of toluene-3,4-Diamine	-	-	1313	Hair dye products	0 %		Details
Salts of thyropropic acid	-	-	9	All cosmetic products	0 %		Details
Salts of the reaction products of ethanol, 2,2'-iminobis- with epichlorohydrin and 2-nitro-1,4-benzenediamine	-	-	1255	Hair dye products	0 %		Details
Salts of thalidomide	-	-	280	All cosmetic products	0 %		Details
Salts of tetryzoline	-	-	394	All cosmetic products	0 %		Details
Salts of tetracaine	-	-	63	All cosmetic products	0 %		Details
Salts of tetrabenazine	-	-	139	All cosmetic products	0 %		Details
Salts of tefazoline	-	-	237	All cosmetic products	0 %		Details
Salts of strychnine	-	-	304	All cosmetic products	0 %		Details
Salts of sparteine	-	-	299	All cosmetic products	0 %		Details
Salts of secondary alkylamines	-	-	411	All cosmetic products	0 %		Details
Salts of secondary alkanolamines	-	-	411	All cosmetic products	0 %		Details
Salts of Rauwolfia serpentina L., alkaloids	-	-	15	All cosmetic products	0 %		Details
Salts of quinoxaline, 1,2,3,4-tetrahydro-6-chloro-	-	-	1240	All cosmetic products	0 %		Details
Salts of procainamide	-	-	25	All cosmetic products	0 %		Details
Salts of pipradrol	-	-	285	All cosmetic products	0 %		Details
Salts of pipazetate	-	-	118	All cosmetic products	0 %		Details
Salts of pilocarpine	-	-	283	All cosmetic products	0 %		Details
Salts of phenoxazin-5-ium, 3,7-bis(diethylamino)-	-	-	1275	Hair dye products	0 %		Details
Salts of phenothiazin-5-ium, 3,7-bis(dimethylamino)-	-	-	1306	Hair dye products	0 %		Details
Salts of phenmetrazine	-	-	232	All cosmetic products	0 %		Details
Salts of phenazinium, 3,7-diamino-2,8-dimethyl-5-phenyl-	-	-	1322	Hair dye products	0 %		Details
Salts of pemoline	-	-	212	All cosmetic products	0 %		Details
Salts of pelletierine	-	-	263	All cosmetic products	0 %		Details
Salts of parethoxycaine	-	-	179	All cosmetic products	0 %		Details
Salts of oxpheneridine	-	-	172	All cosmetic products	0 %		Details
Salts of octodrine	-	-	28	All cosmetic products	0 %		Details
Salts of octamylamine	-	-	267	All cosmetic products	0 %		Details
Salts of octamoxin	-	-	202	All cosmetic products	0 %		Details
Salts of o-phenylenediamine	-	-	363	All cosmetic products	0 %		Details
Salts of O-alkyldithiocarbonic acids	-	-	336	All cosmetic products	0 %		Details
Salts of noscapine	-	-	258	All cosmetic products	0 %		Details
Salts of noradrenaline	-	-	257	All cosmetic products	0 %		Details
Salts of nitroxoline	-	-	209	All cosmetic products	0 %		Details
Salts of nicotine	-	-	246	All cosmetic products	0 %		Details
Salts of neostigmine	-	-	245	All cosmetic products	0 %		Details
Salts of neodymium	-	-	309	All cosmetic products	0 %		Details
Salts of naphazoline	-	-	244	All cosmetic products	0 %		Details
Salts of nalorphine	-	-	20	All cosmetic products	0 %		Details
Salts of N1-(tris(hydroxymethyl))methyl-4-nitro-1,2-phenylenediamine	-	-	1286	Hair dye products	0 %		Details
Salts of N1-(2-hydroxyethyl)-4-nitro-o-phenylenediamine	-	-	1285	Hair dye products	0 %		Details
Salts of N-methyl-3-nitro-p-phenylenediamine	-	-	1284	Hair dye products	0 %		Details
Salts of N-methyl-1,4-diaminoanthraquinone, reaction products with epichlorohydrin and monoethanolamine	-	-	1256	Hair dye products	0 %		Details
Salts of N-[6-[(2-chloro-4-hydroxyphenyl)imino]-4-methoxy-3-oxo-1,4-cyclohexadien-1-yl]acetamide	-	-	1304	Hair dye products	0 %		Details
Salts of N-(5-chloro-2,4-dimethoxyphenyl)-4-[[5-[(diethylamino)sul-phonyl]-2-methoxyphenyl]azo]-3-hydroxynaphthalene-2-carbo-xamide	-	-	1347	Hair dye products	0 %		Details
Salts of N-(2-nitro-4-aminophenyl)-allylamine	-	-	1373	All cosmetic products	0 %		Details
Salts of N,N-dimethyl-p-phenylenediamine	-	-	1312	Hair dye products	0 %		Details
Salts of N,N-diethyl-p-phenylenediamine	-	-	1311	Hair dye products	0 %		Details
Salts of N,N-bis(2-chloroethyl)methylamine N-oxide	-	-	86	All cosmetic products	0 %		Details
Salts of N,N'-pentamethylenebis(trimethylammonium)	-	-	120	All cosmetic products	0 %		Details
Salts of N,N'-hexamethylenebis(trimethylammonium)	-	-	124	All cosmetic products	0 %		Details
Salts of N,N'-dimethyl-N-Hydroxyethyl-3-nitro-p-phenylenediamine	-	-	1288	Hair dye products	0 %		Details
Salts of N,N'-[(Methylimino)diethylene]bis(ethyldimethylammonium)	-	-	121	All cosmetic products	0 %		Details
Salts of morpholine	-	-	344	All cosmetic products	0 %		Details
Salts of minoxidil	-	-	372	All cosmetic products	0 %		Details
Salts of methyprylon	-	-	133	All cosmetic products	0 %		Details
Salts of methylphenidate	-	-	175	All cosmetic products	0 %		Details
Salts of metheptazine	-	-	174	All cosmetic products	0 %		Details
Salts of methapyrilene	-	-	144	All cosmetic products	0 %		Details
Salts of metformin	-	-	147	All cosmetic products	0 %		Details
Salts of metethoheptazine	-	-	171	All cosmetic products	0 %		Details
Salts of metamfepramone	-	-	145	All cosmetic products	0 %		Details
Salts of mefeclorazine	-	-	141	All cosmetic products	0 %		Details
Salts of mannomustine	-	-	89	All cosmetic products	0 %		Details
Salts of m-phenylenediamine, 4-(phenylazo)-	-	-	1293	Hair dye products	0 %		Details
Salts of m-phenylenediamine	-	-	1204	All cosmetic products	0 %		Details
Salts of lysergide	-	-	127	All cosmetic products	0 %		Details
Salts of lobeline	-	-	219	All cosmetic products	0 %		Details
Salts of levofacetoperane	-	-	284	All cosmetic products	0 %		Details
Salts of laccaic acid	-	-	1279	Hair dye products	0 %		Details
Salts of isometheptene	-	-	228	All cosmetic products	0 %		Details
Salts of isobutyl 4-hydroxybenzoate	-	-	1375	All cosmetic products	0 %		Details
Salts of hyoscyamine	-	-	210	All cosmetic products	0 %		Details
Salts of hyoscine	-	-	295	All cosmetic products	0 %		Details
Salts of hydroxypyridinone	-	-	1249	Hair dye products	0 %		Details
Salts of hydroxyethylaminomethyl-p-aminophenol	-	-	1316	Hair dye products	0 %		Details
Salts of hydroxyethyl-2,6-dinitro-p-anisidine	-	-	1320	Hair dye products	0 %		Details
Salts of hydrogen cyanide	-	-	111	All cosmetic products	0 %		Details
Salts of hydrazine show/hide Hydrazinium dihydrogen phosphate EC / List no: 239-919-9 \| CAS no: 15823-35-5 Hydrazine, diperchlorate EC / List no: - \| CAS no: 13812-39-0 Hydrazine, monohydrofluoride EC / List no: - \| CAS no: 18220-64-9 Hydrazine, dihydrobromide, dihydrate EC / List no: - \| CAS no: 40849-90-9 Hydrazine, dinitrate EC / List no: - \| CAS no: 13464-98-7 Hydrazine, hydriodide (3:2) EC / List no: - \| CAS no: 10034-92-1 Hydrazine dihydrobromide EC / List no: 245-543-6 \| CAS no: 23268-00-0 Hydrazine Acetate EC / List no: 629-465-3 \| CAS no: 13255-48-6 Dithiocarbazic acid, compound with hydrazine (1:1) EC / List no: 243-844-7 \| CAS no: 20469-71-0 Compound of carbonic acid with hydrazine(1:2) EC / List no: - \| CAS no: 112077-84-6 Hydrazine, monohydriodide EC / List no: - \| CAS no: 10039-55-1 Hydrazine dihydrochloride EC / List no: 226-283-2 \| CAS no: 5341-61-7 Dihydrazinium sulphate EC / List no: 236-688-6 \| CAS no: 13464-80-7 1,2,4-triazolidine-3,5-dione, compound with hydrazine (1:1) EC / List no: 264-246-2 \| CAS no: 63467-96-9 Hydrazine tartrate EC / List no: 211-211-4 \| CAS no: 634-62-8 Hydrazine, sulfate EC / List no: - \| CAS no: 1184-66-3 Hydrazine, diperchlorate, dihydrate EC / List no: - \| CAS no: 73497-82-2 Hydrazine, hydrochloride EC / List no: - \| CAS no: 14011-37-1 Hydrazinium bromide EC / List no: 237-412-7 \| CAS no: 13775-80-9 Nitroformic acid, compound with hydrazine (1:1) EC / List no: 244-023-6 \| CAS no: 20773-28-8 Hydrazine, phosphate EC / List no: - \| CAS no: 23488-13-3 Hydrazine selenate EC / List no: - \| CAS no: 73506-32-8 Hydrazine, phosphate (2:1) EC / List no: - \| CAS no: 59779-45-2 Hydrazine, sulfate (2:1), monohydrate EC / List no: - \| CAS no: 66375-32-4 Hydrazine perchlorate EC / List no: - \| CAS no: 27978-54-7 Hydrazine, nitrate EC / List no: - \| CAS no: 37836-27-4 Hydrazinium nitrate EC / List no: 236-690-7 \| CAS no: 13464-97-6 Hydrazinium sulphamate EC / List no: 254-708-1 \| CAS no: 39935-03-0 Hydrazine difluoride EC / List no: - \| CAS no: 13537-45-6 Thiocyanic acid, compd. with hydrazine (1:1) EC / List no: - \| CAS no: 24786-78-5 Hydrazinium chloride EC / List no: 220-154-4 \| CAS no: 2644-70-4 Hydrazinium acetate EC / List no: 230-845-2 \| CAS no: 7335-65-1 Hydrazinium(2+) sulphate EC / List no: 233-110-4 \| CAS no: 10034-93-2	-	-	201	All cosmetic products	0 %		Details
Salts of hydrazides	-	-	200	All cosmetic products	0 %		Details
Salts of hydrastinine	-	-	199	All cosmetic products	0 %		Details
Salts of hydrastine	-	-	199	All cosmetic products	0 %		Details
Salts of HC Red No 8	-	-	1239	All cosmetic products	0 %		Details
Salts of HC Blue No 10	-	-	1326	Hair dye products	0 %		Details
Salts of guanethidine	-	-	259	All cosmetic products	0 %		Details
Salts of glutethimide	-	-	181	All cosmetic products	0 %		Details
Salts of ethyl bis(4-hydroxy-2-oxo-1-benzopyran-3-yl)acetic acid	-	-	204	All cosmetic products	0 %		Details
Salts of ethoheptazine	-	-	173	All cosmetic products	0 %		Details
Salts of ethanaminium, N-[4-[[4-(diethylamino)phenyl][4-(ethylamino)-1-naphthalenyl] methylene]-2,5-cyclohexadien-1-ylidene]-N-ethyl-	-	-	1328	Hair dye products	0 %		Details
Salts of ethanaminium, N-[4-[(4-(diethylamino)phenyl)phenylmethylene]-2,5-cyclohexadien-1-ylidene]-N-ethyl-	-	-	1299	Hair dye products	0 %		Details
Salts of ethanaminium, N-(4-[bis[4-(diethylamino)phenyl]methylene]-2,5-cyclohexadien-1-ylidene)-N-ethyl-	-	-	1271	Hair dye products	0 %		Details

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