cosmetics-prohibited-subs

cosmetics-prohibited-subs

Cosmetic Products Regulation, Annex II - Prohibited Substances

EU. Prohibited Substances: Annex II, Regulation 1223/2009/EC on Cosmetic Products, as amended by Regulation (EU) 2023/1490, OJ L 183, 20 July 2023

This list contains substances which are banned from use in any cosmetic products marketed for sale or use in the European Union.

Last updated 19 April 2024. Database contains 2528 unique substances/entries.

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Showing 151 - 200 of 2,528 results.

Substance Name	EC No.	CAS No.	Ref No.	Product type, body parts	Maximum Threshold	Restriction(s)
N,N-Dimethyl-2,6-Pyridinediamine and its HCl salt	-	-	1224	Hair dye products	0 %		Details
N-(2-Methoxyethyl)-p-phenylenediamine	-	66566-48-1	1226	Hair dye products	0 %		Details
N-(2-Nitro-4-aminophenyl)-allylamine	-	160219-76-1	1373	All cosmetic products	0 %		Details
N-(5-Chlorobenzoxazol-2-yl)acetamide	-	35783-57-4	1	All cosmetic products	0 %		Details
N-Cyclopentyl-m-Aminophenol	-	104903-49-3	1225	Hair dye products	0 %		Details
N-Methyl-1,4-diaminoanthraquinone, reaction products with epichlorohydrin and monoethanolamine	-	158571-57-4	1256	Hair dye products	0 %		Details
n-Pentyl-isopentylphthalate	-	-	1151	All cosmetic products	0 %		Details
Narcotics, natural and synthetic	-	-	306	All cosmetic products	0 %	All substances listed in Tables I and II of the Single Convention on Narcotic Drugs signed in New York on 30 March 1961	Details
Neostigmine	-	59-99-4	245	All cosmetic products	0 %		Details
Nickel boron phosphide	-	65229-23-4	1462	All cosmetic products	0 %		Details
Nickel dilactate	-	16039-61-5	1433	All cosmetic products	0 %		Details
Nickel potassium fluoride	-	11132-10-8	1435	All cosmetic products	0 %		Details
Nitrite(1-)	-	14797-65-0	248	All cosmetic products	0 %		Details
Nitrocresols	-	12167-20-3	250	All cosmetic products	0 %		Details
Nitroderivatives of carbazole	-	-	72	All cosmetic products	0 %		Details
Nitrosamines	-	-	410	All cosmetic products	0 %		Details
Nitrostilbenes, their homologues and their derivatives	-	-	256	All cosmetic products	0 %		Details
Normal salts, complexes and hydrofluorides of hydrofluoric acid	-	-	191	All cosmetic products	0 %	Not permitted except for those given in Annex III	Details
O,O'-Diacetyl-N-allyl-N-normorphine	-	2748-74-5	117	All cosmetic products	0 %		Details
o-Dianisidine based azo dyes show/hide 6,6'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[4-amino-5-hydroxynaphthalene-1,3-disulphonic] acid EC / List no: 223-333-5 \| CAS no: 3841-14-3 5,5'-(3,3'-Dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(1-(4-nitrophenyl)-3-phenylformazan) EC / List no: - \| CAS no: 63469-14-7 Tetrasodium 3,3'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[5-amino-4-hydroxynaphthalene-2,7-disulphonate] EC / List no: 219-385-3 \| CAS no: 2429-74-5 Benzoic acid, 4,4'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(2,1-diazenediyl(2-acetyl-1-oxo-2,1-ethanediyl)imino))bis-, 1,1'-dibutyl ester EC / List no: - \| CAS no: 820212-95-1 Tetrasodium 4,4'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[3-hydroxynaphthalene-2,7-disulphonate] EC / List no: 265-533-5 \| CAS no: 65151-33-9 2,2'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(4-chlorophenyl)-3-oxobutyramide] EC / List no: 241-469-3 \| CAS no: 17453-73-5 Tetrasodium 3,3'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[5-(acetylamino)-4-hydroxynaphthalene-2,7-disulphonate] EC / List no: 267-711-8 \| CAS no: 67906-44-9 2,7-Naphthalenedisulfonic acid, 3,3'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(2,1-diazenediyl))bis(5-amino-4-hydroxy-, lithium sodium salt (1:1:3) EC / List no: - \| CAS no: 75659-72-2 3,3'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)diazo]bis[5-amino-4-hydroxynaphthalene-2,7-disulphonic] acid, sodium salt, compound with 2,2'-iminodiethanol EC / List no: 273-433-8 \| CAS no: 68966-43-8 3,3'-dihydroxy-N,N'-(3,3'-dimethoxybiphenyl-4,4'-diyl)di-2-naphthamide EC / List no: 202-108-5 \| CAS no: 91-92-9 Disodium 3,3'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis(4-hydroxynaphthalene-1-sulphonate) EC / List no: 219-382-7 \| CAS no: 2429-71-2 5,5'-diphenyl-3,3'-bis(4-nitrophenyl)-2,2'-(3,3'-dimethoxybiphenyl-4,4'-ylene)ditetrazolium dichloride EC / List no: 206-067-4 \| CAS no: 298-83-9 3,3'-(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis[2,5-bis(p-nitrophenyl)-2H-tetrazolium] dichloride EC / List no: 214-665-1 \| CAS no: 1184-43-6 Copper, 3,3'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(2,1-diazenediyl))bis(5-amino-4-hydroxy-2,7-naphthalenedisulfonate) morpholine ammonium lithium sodium complexes EC / List no: - \| CAS no: 96591-22-9 Disodium 4,4'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis[iminocarbonyl(2-hydroxy-4,1-phenylene)azo]]bis(3-hydroxynaphthalene-1-sulphonate) EC / List no: 274-498-5 \| CAS no: 70247-69-7 1-Naphthalenesulfonic acid, 3,3'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(2,1-diazenediyl))bis(4-hydroxy-, lithium sodium salt (1:1:1) EC / List no: - \| CAS no: 75673-35-7 Disodium 2,2'-[(3,3'-dimethoxy-4,4'-biphenylylene)bis[azo(methylimino)]]di(ethanesulphonate) EC / List no: 241-085-6 \| CAS no: 17011-51-7 Tetrasodium 2,2'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis[azo(2-amino-5-hydroxy-7-sulphonato-6,1-naphthylene)azo]]bis[5-nitrobenzoate] EC / List no: 274-429-9 \| CAS no: 70210-33-2 3,3'-(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis[5-[4-(aminothioxomethyl)phenyl]-2-(p-nitrophenyl)-2H-tetrazolium] dichloride EC / List no: 253-257-8 \| CAS no: 36889-43-7 Butanamide, 2,2'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(2,1-diazenediyl))bis(N-(chlorophenyl)-3-oxo- EC / List no: - \| CAS no: 72845-99-9 2,2'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[3-oxo-N-phenylbutyramide] EC / List no: 229-388-1 \| CAS no: 6505-28-8 2,7-Naphthalenedisulfonic acid, 3,3'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(2,1-diazenediyl))bis(5-amino-4-hydroxy-, lithium sodium salt (1:3:1) EC / List no: - \| CAS no: 75752-17-9 Tetralithium 3,3'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[5-amino-4-hydroxynaphthalene-2,7-disulphonate] EC / List no: 275-603-7 \| CAS no: 71550-22-6 4,4'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one] EC / List no: 229-389-7 \| CAS no: 6505-29-9 2,2'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(2,4-dimethylphenyl)-3-oxobutyramide] EC / List no: 229-920-2 \| CAS no: 6837-37-2 3,3'-(3,3'-dimethoxy-4,4'-biphenylene)bis(2,5-diphenyl-2H-tetrazolium) chloride EC / List no: 217-488-8 \| CAS no: 1871-22-3 2,7-Naphthalenedisulfonic acid, 3,3'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(2,1-diazenediyl))bis(5-amino-4-hydroxy-, lithium sodium salt (1:2:2) EC / List no: - \| CAS no: 75659-73-3 4,4'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[3-hydroxy-N-(2-methoxyphenyl)naphthalene-2-carboxamide] EC / List no: 226-614-0 \| CAS no: 5437-88-7 4,4'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[2,4-dihydro-5-methyl-2-(p-tolyl)-3H-pyrazol-3-one] EC / List no: 229-986-2 \| CAS no: 6883-91-6 4,4'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[3-hydroxy-N-phenylnaphthalene-2-carboxamide] EC / List no: 233-354-1 \| CAS no: 10127-03-4 1-Naphthalenesulfonic acid, 3,3'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(2,1-diazenediyl))bis(4-hydroxy-, lithium salt (1:2) EC / List no: - \| CAS no: 75673-34-6 3,3'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)diazo]bis[5-amino-4-hydroxynaphthalene-2,7-disulphonic] acid, sodium salt EC / List no: 273-439-0 \| CAS no: 68966-50-7 Tetrasodium 3,3'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[4,5-dihydroxynaphthalene-2,7-disulphonate] EC / List no: 224-091-3 \| CAS no: 4198-19-0 2,2'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(2-methylphenyl)-3-oxobutyramide] EC / List no: 230-458-9 \| CAS no: 7147-42-4 N,N'-(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis[3-oxobutyramide] EC / List no: 223-873-1 \| CAS no: 4104-12-5 Tetrasodium 6,6'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[4-amino-5-hydroxynaphthalene-1,3-disulphonate] EC / List no: 220-026-8 \| CAS no: 2610-05-1 2-Naphthalenecarboxamide, N,N'-(3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(3-hydroxy-, disodium salt EC / List no: - \| CAS no: 52735-88-3	-	-	711	All cosmetic products	0 %		Details
o-Tolidine based dyes show/hide Disodium 3,3'-[(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[2,4-diamino-5-methylbenzenesulphonate] EC / List no: 229-024-1 \| CAS no: 6405-94-3 Disodium 3,3'-((3,3'-dimethyl(1,1'-biphenyl)-4,4'-diyl)bis(azo)bis(4-aminonaphthalene-1-sulphonate) EC / List no: 213-594-3 \| CAS no: 992-59-6 Tetrasodium 3,3'-[(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[5-amino-4-hydroxynaphthalene-2,7-disulphonate] EC / List no: 200-786-7 \| CAS no: 72-57-1 N,N'-(3,3'-dimethylbiphenyl-4,4'-ylene)di(acetoacetamide) EC / List no: 202-111-1 \| CAS no: 91-96-3 Tetrasodium 6,6'-((3,3'-dimethyl-(1,1'-biphenyl-4,4'diyl)bis(azo)bis(4-amino-5-hydroxy-1,3-naphthalenedisulphonate) EC / List no: 206-242-5 \| CAS no: 314-13-6 N,N'-(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[3-oxobutyramide], disodium salt EC / List no: 271-328-1 \| CAS no: 68540-94-3 N,N'-(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(3-hydroxynaphthalene-2-carboxamide) EC / List no: 223-007-2 \| CAS no: 3692-05-5 Tetrasodium 3,3'-[(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[4,5-dihydroxynaphthalene-2,7-disulphonate] EC / List no: 218-432-5 \| CAS no: 2150-54-1 2,2'-[(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[3-oxo-N-phenylbutyramide] EC / List no: 228-789-9 \| CAS no: 6358-88-9 2,2'-[(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[4-nonylphenol] EC / List no: 268-048-7 \| CAS no: 67990-27-6 Benzamide, 3,3'-((3,3'-dimethyl(1,1'-biphenyl)-4,4'-diyl)bis(imino(1-acetyl-2-oxo-2,1-ethanediyl)-2,1-diazenediyl))bis(4-methyl- EC / List no: - \| CAS no: 64441-14-1 N,N'-(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[2-[(2,4-dichlorophenyl)azo]-3-oxobutyramide] EC / List no: 227-783-3 \| CAS no: 5979-28-2 3,3'-[(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[imino(1-acetyl-2-oxoethane-1,2-diyl)azo]]bis[bis(3-aminopropyl)(p-methoxybenzyl)methylammonium] dichloride EC / List no: 255-154-3 \| CAS no: 40948-42-3 2,2'-[(3,3'-dimethyl-4,4'-biphenylylene)bis(azo)]bis[4-(1,1,3,3-tetramethylbutyl)phenol] EC / List no: 230-616-7 \| CAS no: 7218-82-8	-	-	725	All cosmetic products	0 %		Details
Octaborates	-	-	1396	All cosmetic products	0 %		Details
Octamoxin	-	4684-87-1	202	All cosmetic products	0 %		Details
Oestrogens	-	-	260	All cosmetic products	0 %		Details
Oxanamide	-	126-93-2	165	All cosmetic products	0 %		Details
Oxpheneridine	-	546-32-7	172	All cosmetic products	0 %		Details
Parethoxycaine	-	94-23-5	179	All cosmetic products	0 %		Details
PEG-3,2',2'-di-p-Phenylenediamine	-	144644-13-3	1234	All cosmetic products	0 %		Details
Perfluorononan-1-oic acid sodium salt	-	21049-39-8	1636	All cosmetic products	0 %		Details
Petrichloral	-	78-12-6	266	All cosmetic products	0 %		Details
Phenazinium, 3,7-diamino-2,8-dimethyl-5-phenyl-	-	7006-08-8	1322	Hair dye products	0 %		Details
Phenothiazin-5-ium, 3,7-bis(dimethylamino)-	-	-	1306	Hair dye products	0 %		Details
Phenothiazine compounds	-	-	320	All cosmetic products	0 %		Details
Phenoxazin-5-ium, 3,7-bis(diethylamino)-	-	47367-75-9	1275	Hair dye products	0 %		Details
Phosphoric acid, calcium nickel salt	-	17169-61-8	1438	All cosmetic products	0 %		Details
Phytolacca spp. and their preparations	-	-	374	All cosmetic products	0 %		Details
Phytolaccasaponin B	-	60820-94-2	374	All cosmetic products	0 %		Details
Progestogens	-	-	194	All cosmetic products	0 %		Details
Pyrethrum album L. and its galenical preparations	-	-	345	All cosmetic products	0 %		Details
Quinoxaline, 1,2,3,4-tetrahydro-6-chloro-	-	73855-45-5	1240	All cosmetic products	0 %		Details
Radioactive substances	-	-	293	All cosmetic products	0 %	As defined by Directive 96/29/Euratom (OJ L 159, 29.6.1996, p. 1) laying down basic safety standards for the protection of the health of workers and the general public against the dangers arising from ionising radiation.	Details
Reaction products of paraformaldehyde with 2-hydroxypropylamine (1:1)	-	-	1607	All cosmetic products	0 %	If the maximum theoretical concentration of releasable formaldehyde, irrespective of the source, in the mixture as placed on the market is ≥ 0.1 % w/w	Details
Reaction products of paraformaldehyde with 2-hydroxypropylamine (3:2)	-	-	1606	All cosmetic products	0 %	If the maximum theoretical concentration of releasable formaldehyde, irrespective of the source, in the mixture as placed on the market is ≥ 0.1 % w/w	Details
Salts and esters of dinoseb show/hide Sodium 2-(1-methylpropyl)-4,6-dinitrophenolate EC / List no: 252-331-7 \| CAS no: 35040-03-0 2-sec-butyl-4,6-dinitrophenol, compound with 2,2'-iminodiethanol (1:1) EC / List no: 258-532-6 \| CAS no: 53404-43-6 2-sec-butyl-4,6-dinitrophenol, compound with 2,2',2''-nitrilotriethanol (1:1) EC / List no: 229-166-4 \| CAS no: 6420-47-9 Dinoseb acetate EC / List no: 220-560-1 \| CAS no: 2813-95-8 Binapacryl EC / List no: 207-612-9 \| CAS no: 485-31-4 2-sec-butyl-4,6-dinitrophenol, compound with 1-aminopropan-2-ol (1:1) EC / List no: 275-931-0 \| CAS no: 71735-19-8 Ammonium 2-sec-butyl-4,6-dinitrophenolate EC / List no: 228-858-3 \| CAS no: 6365-83-9	-	-	684	All cosmetic products	0 %	With the exception of those specified elsewhere in this list	Details
Salts and esters of dinoterb show/hide 2-tert-butyl-4,6-dinitrophenyl acetate EC / List no: 221-706-7 \| CAS no: 3204-27-1	-	-	696	All cosmetic products	0 %		Details
Salts of (2-acetoxyethyl)trimethylammonium hydroxide	-	-	2	All cosmetic products	0 %		Details
Salts of (8-[(4-amino-2-nitrophenyl)azo]-7-hydroxy-2-naphthyl) trimethylammonium	-	-	1291	Hair dye products	0 %	When used in hair dye products. Not permitted except for Basic Red 118 as impurity in Basic Brown 17	Details
Salts of (R)-1-(2-piperidyl)acetone	-	-	263	All cosmetic products	0 %		Details
Salts of (µ-((7,7'-iminobis(4-hydroxy-3-((2-hydroxy-5-(N-methylsulphamoyl) phenyl)azo)naphthalene-2-sulphonato))(6-)))dicuprate(2-)	-	-	1268	Hair dye products	0 %		Details
Salts of 1,1-bis(dimethylaminomethyl)propyl benzoate	-	-	143	All cosmetic products	0 %		Details

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