Endocrine disruptor assessment list

Endocrine disruptor assessment list

Endocrine disruptor assessment list

ECHA’s endocrine disruptor (ED) assessment list includes the substances undergoing an ED assessment that have been brought for discussion to ECHA’s ED Expert Group.

Explanatory note

Inclusion in the list means that an informal hazard assessment for endocrine-disrupting properties either is under development or has been completed since February 2013.

For each substance, the table shows the assessing or evaluating Member State (submitter), the outcome from the assessment, and the date of the latest update to the list entry.

Other process details and hazard assessment outcome documents are also available and can be accessed through the ‘Details’ icon.

One possible outcome of such an assessment is that a substance is considered not to have ED properties.

If the outcome is that the substance is considered to have ED properties, confirmation through the formal risk management and decision-making processes under is needed before any regulatory action can be taken due to these properties.

The intentions of authorities to submit a dossier to the formal REACH and CLP processes are notified through the Registry of Intentions. All biocidal active substances have to undergo a formal ED assessment. You can see the status of biocides assessments on the Biocidal Active Substances page.

Disclaimer

The information and views set out in the ED assessment list and in the hazard assessment outcome documents are those of the evaluating authority and do not necessarily reflect the position or opinion of the other Member States or ECHA. Neither ECHA nor the evaluating authority nor any person acting on either of their behalves may be held liable for the use, which may be made of the information contained therein. Statements made or information contained in the documents are without prejudice to any formal regulatory activities that ECHA or the Member States may initiate at a later stage. ED assessments and their outcomes are compiled on the basis of information available by the date of the publication of the document.

Sodium perfluoroheptanoate

EC / List no: 243-518-4 CAS no: 20109-59-5
Concern
Endocrine disruption
Status
Concluded
Outcome
inconclusive
Date of intention
28-Aug-2018
Date of hazard assessment
Hazard assessment outcome document
Remarks
This substance is a degradation product of EC# 700-403-8, that was included in CoRAP 2013 and the SEv is concluded.
"Concern unresolved:
As a result of the evaluation of the submitted reproduction
developmental toxicity screening study in mice with sodium
perfluoroheptanoate, a potential for endocrine disrupting properties
is recognised. Based on the available information a definitive
conclusion could not be drawn, but in view of the ongoing restriction
proposal for undecafluorohexanoic acid, its salts and related
substances, further examination is not expected to result in
additional Risk Management Measures for the Substance.
5 ECHA Candidate List of substances of very high concern for Authorisation. Perfluoroheptanoic acid and its salts.
In the conclusion document for EC No 241-527-86 and EC No 218-
407-97, the German CA concluded that the available data clarifies
that PFHxA acts as an ED for the environment in accordance with
the Endocrine Disruptor definition of the World Health Organisation
(WHO).
However, for the moment there is no official identification of PFHxA
as ED for the environment by MSC or RAC."
Authority
Belgium
Submitter organisation
Federal public Service Health, Food Chain Safety and Environment
Submitter email
evaluation.reach@environment.belgium.be
Submitter phone
Submitter address
Federal Public Service Health, Food Chain Safety and Environment
Co-submitter(s)
Latest update
24-Jun-2024
First published
20-Jan-2021