EU-IMPLANTABLE_MEDICAL_DEVICES-ART_3_ANX_1

Active Implantable Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 90/385/EEC on Active Implantable Medical Devices, 20 July 1990, amended by Directive 2007/47/EC, 21 September 2007

This list contains hazardous substances for purposes of Directive 90/385/EEC on active implantable medical devices, particularly as regards Article 3 and Annex I (Essential Requirements). This non-exhaustive database is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list). Please note that Regulation (EU) 2017/745 on medical devices has repealed Directive 90/385/EEC and begun to apply from 26 May 2021. Nevertheless, Article 120 of the Regulation provides for a transitional period allowing medical devices, under specified conditions (e.g., placed on the market prior to 26 May 2021), to continue to comply with the Directive. In accordance with the fourth paragraph of Article 120, this period ends 26 May 2025.

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Last updated 19 January 2022. Database contains 4753 unique substances/entries.
Substance Name EC No. CAS No. EU CLP (1272/2008) EU_BA Directive 2000/54/EC EU REACH: List of SVHC
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Mercury, iodophenyl- ecnumber: 664-429-0 | casnumber: 823-04-1
[salicylato(2-)-O1,O2]mercury ecnumber: 227-760-8 | casnumber: 5970-32-1
methylmercury salts ecnumber: 694-823-8 | casnumber: 22967-92-6
2-methoxyethylmercury acetate ecnumber: 205-790-2 | casnumber: 151-38-2
4-(Chloromercuri)benzenesulfonic acid monosodium salt ecnumber: 683-356-5 | casnumber: 14110-97-5
(2-carboxyphenyl)hydroxymercury ecnumber: 237-918-8 | casnumber: 14066-61-6
Amylmercury chloride ecnumber: - | casnumber: 544-15-0
Dipotassium tetracyanomercurate ecnumber: 209-735-3 | casnumber: 591-89-9
Merbromin ecnumber: 204-933-6 | casnumber: 129-16-8
[naphthoato(1-)-O]phenylmercury ecnumber: 250-736-3 | casnumber: 31632-68-5
4-chloromercuriobenzoic acid ecnumber: 200-442-6 | casnumber: 59-85-8
Mercury, chloro(4-((2,4-dinitrophenyl)amino)phenyl)- ecnumber: - | casnumber: 15785-93-0
Phenylmercury nitrate ecnumber: 200-242-9 | casnumber: 55-68-5
Disodium tetra(cyano-C)mercurate(2-) ecnumber: 239-766-8 | casnumber: 15682-88-9
Mercury dithizonate ecnumber: 621-496-0 | casnumber: 14783-59-6
(phenylmercurio)urea ecnumber: 218-909-8 | casnumber: 2279-64-3
Disuccinimidomercury ecnumber: 209-537-7 | casnumber: 584-43-0
(oleato)phenylmercury ecnumber: 203-218-6 | casnumber: 104-60-9
(dihydroxyphenyl)phenylmercury ecnumber: 248-426-8 | casnumber: 27360-58-3
Mercury acetate ecnumber: 209-766-2 | casnumber: 592-63-2
Mercury bis(4-chlorobenzoate) ecnumber: 239-548-2 | casnumber: 15516-76-4
Methylmercury benzoate ecnumber: 222-834-6 | casnumber: 3626-13-9
Di-sec-butylmercury ecnumber: - | casnumber: 691-88-3
Di-o-tolylmercury ecnumber: 210-499-9 | casnumber: 616-99-9
Phenylmercury hydroxide ecnumber: 202-866-7 | casnumber: 100-57-2
Chloromethylmercury ecnumber: 204-064-2 | casnumber: 115-09-3
Phenyl(tribromomethyl)mercury ecnumber: 221-963-5 | casnumber: 3294-60-8
Di(acetato-O)anilinemercury ecnumber: 264-306-8 | casnumber: 63549-47-3
(acetato-O)ethylmercury ecnumber: 203-688-2 | casnumber: 109-62-6
Trimercury biscitrate ecnumber: 242-096-9 | casnumber: 18211-85-3
3-(Acetoxymercuri)pyridine ecnumber: - | casnumber: 102-99-8
(metaborato-O)phenylmercury ecnumber: 250-518-8 | casnumber: 31224-71-2
Diiodo(5-iodopyridin-2-amine-N1)mercury ecnumber: 298-602-3 | casnumber: 93820-20-3
[μ-[orthoborato(2-)-O:O']]diphenyldimercury ecnumber: 228-465-7 | casnumber: 6273-99-0
Mercury(2+) chloroacetate ecnumber: 247-925-8 | casnumber: 26719-07-3
Dimercury di(acetate) ecnumber: 211-161-3 | casnumber: 631-60-7
Ethyliodomercury ecnumber: 219-471-0 | casnumber: 2440-42-8
Thiomersal ecnumber: 200-210-4 | casnumber: 54-64-8
[benzoato(2-)-C2,O1]mercury ecnumber: 227-228-5 | casnumber: 5722-59-8
Methyl(pentachlorophenolato)mercury ecnumber: 227-596-7 | casnumber: 5902-76-1
Chloro[p-[(2-hydroxy-1-naphthyl)azo]phenyl]mercury ecnumber: 221-358-6 | casnumber: 3076-91-3
Mercury bis(trifluoroacetate) ecnumber: 236-250-4 | casnumber: 13257-51-7
Chlormerodrin ecnumber: 200-530-4 | casnumber: 62-37-3
Mercury bis(2-ethylhexanoate) ecnumber: 236-113-9 | casnumber: 13170-76-8
Ethanethiolmercury chloride ecnumber: - | casnumber: 1785-43-9
(3-chloro-4-hydroxyphenyl)mercury;hydrate ecnumber: - | casnumber: 538-04-5
[(2-hydroxyethyl)amino]phenylmercury acetate ecnumber: 263-211-9 | casnumber: 61792-06-1
Iodomethylmercury ecnumber: 205-600-8 | casnumber: 143-36-2
(neodecanoato-O)phenylmercury ecnumber: 247-783-7 | casnumber: 26545-49-3
[2-ethylhexyl hydrogen maleato-O']phenylmercury ecnumber: 248-559-1 | casnumber: 27605-30-7
4-aminophenylmercury acetate ecnumber: 228-497-1 | casnumber: 6283-24-5
Mercury(2+) tetrakis(thiocyanato-N)cobaltate(2-) ecnumber: 248-602-4 | casnumber: 27685-51-4
Mercury, bis(phenylmethyl)- ecnumber: 677-698-4 | casnumber: 780-24-5
Phenylmercury benzoate ecnumber: 202-331-8 | casnumber: 94-43-9
mercury, chloro(3-hydroxyphenyl)- ecnumber: - | casnumber: 70538-27-1
Mercury, (acetato)pyridyl- (8CI) ecnumber: - | casnumber: 1334-77-6
Mercury dioleate ecnumber: 214-741-4 | casnumber: 1191-80-6
[2,2',2''-nitrilotri(ethanol)-N,O,O',O'']phenylmercury lactate ecnumber: 245-581-3 | casnumber: 23319-66-6
Otimerate sodium ecnumber: 240-572-0 | casnumber: 16509-11-8
Mersalyl acid ecnumber: 207-637-5 | casnumber: 486-67-9
Phenylmercury salicylate ecnumber: 248-828-3 | casnumber: 28086-13-7
Dipropyl mercury ecnumber: - | casnumber: 628-85-3
Phenyl(trichloromethyl)mercury ecnumber: 221-960-9 | casnumber: 3294-57-3
Bromoethylmercury ecnumber: 203-477-5 | casnumber: 107-26-6
Mercury, diheptyl- ecnumber: - | casnumber: 51622-02-7
Phenylmercury chloride ecnumber: 202-865-1 | casnumber: 100-56-1
Di(phenylmercury) dodecylsuccinate ecnumber: - | casnumber: 24806-32-4
(2-ethylhexanoato)phenylmercury ecnumber: 236-326-7 | casnumber: 13302-00-6
Ethylmercury chloride ecnumber: 203-478-0 | casnumber: 107-27-7
Mercurate(2-), tetraiodo-, copper(2+) (1:1), (T-4)- ecnumber: - | casnumber: 27228-67-7
Bis(5-oxo-DL-prolinato-N1,O2)mercury ecnumber: 304-523-8 | casnumber: 94276-38-7
Chloro-2-thienylmercury ecnumber: 227-481-1 | casnumber: 5857-39-6
BMC ecnumber: 663-974-1 | casnumber: 543-63-5
Diphenyl[μ-[(tetrapropenyl)succinato(2-)-O:O']]dimercury ecnumber: 248-355-2 | casnumber: 27236-65-3
Phenylmercuric phthalate ecnumber: 664-337-0 | casnumber: 84-70-8
Meralein sodium ecnumber: 224-498-6 | casnumber: 4386-35-0
1-cyano-3-(methylmercurio)guanidine ecnumber: 207-935-5 | casnumber: 502-39-6
Mercury dibenzoate ecnumber: 209-499-1 | casnumber: 583-15-3
Bis[(+)-lactato]mercury ecnumber: 251-657-7 | casnumber: 33724-17-3
2-hydroxy-5-(1,1,3,3-tetramethylbutyl)phenylmercury acetate ecnumber: 209-534-0 | casnumber: 584-18-9
Chloromercuriferrocene ecnumber: 631-381-7 | casnumber: 1273-75-2
Lactic acid, mercury(2+) salt (2:1) (8CI) ecnumber: - | casnumber: 814-82-4
2-chloromercuriophenol ecnumber: 201-962-6 | casnumber: 90-03-9
2-methoxyethylmercury chloride ecnumber: 204-659-7 | casnumber: 123-88-6
Bis(trichloromethyl)mercury ecnumber: 229-867-5 | casnumber: 6795-81-9
Mercury distearate ecnumber: 211-458-8 | casnumber: 645-99-8
Mercury di(acetate) ecnumber: 216-491-1 | casnumber: 1600-27-7
Sodium 4-chloromercuriobenzoate ecnumber: 221-700-4 | casnumber: 3198-04-7
Mercurous gluconate ecnumber: - | casnumber: 63937-14-4
Bromomethylmercury ecnumber: 208-057-5 | casnumber: 506-83-2
(2,3,4,5,6-pentachlorophenoxy)-phenylmercury ecnumber: - | casnumber: 1142-64-9
2-(ethylmercuriothio)benzoic acid ecnumber: 205-719-5 | casnumber: 148-61-8
Chloro-o-tolylmercury ecnumber: 220-469-7 | casnumber: 2777-37-9
Phenylmercury propionate ecnumber: 203-094-3 | casnumber: 103-27-5
4-Chloromercuriphenol ecnumber: - | casnumber: 623-07-4
(maleoyldioxy)bis[phenylmercury] ecnumber: 220-286-2 | casnumber: 2701-61-3
[μ-[metasilicato(2-)-O:O]]bis(2-methoxyethyl)dimercury ecnumber: 242-997-7 | casnumber: 19367-79-4
Mersalyl ecnumber: 207-748-9 | casnumber: 492-18-2
Diisopropylmercury ecnumber: - | casnumber: 1071-39-2
Mercury, iodo(trifluoromethyl)- ecnumber: - | casnumber: 421-11-4
(acetato-O)[3-(chloromethoxy)propyl-C,O]mercury ecnumber: 227-719-4 | casnumber: 5954-14-3
Bis(ethylthio)mercury ecnumber: - | casnumber: 811-50-7
Dimethyl[μ-[sulphato(2-)-O:O']]dimercury ecnumber: 223-288-1 | casnumber: 3810-81-9
Hydrogen [metasilicato(2-)-O](2-methoxyethyl)mercurate(1-) ecnumber: 264-920-6 | casnumber: 64491-92-5
Bromo(2-hydroxypropyl)mercury ecnumber: 242-613-8 | casnumber: 18832-83-2
Dimethylmercury ecnumber: 209-805-3 | casnumber: 593-74-8
(4-((4-(Dimethylamino)phenyl)azo)phenyl)mercuric acetate ecnumber: 631-561-5 | casnumber: 19447-62-2
Mercurobutol ecnumber: 207-869-7 | casnumber: 498-73-7
Mercury succinate ecnumber: 209-656-4 | casnumber: 589-65-1
Mercury(1+) ethyl sulphate ecnumber: 275-904-3 | casnumber: 71720-55-3
Iodo(iodomethyl)mercury ecnumber: 205-485-4 | casnumber: 141-51-5
[μ-[(oxydiethylene but-2-enedioato)(2-)]]diphenyldimercury ecnumber: 301-791-8 | casnumber: 94070-92-5
Tris(ethylmercury) phosphate ecnumber: 218-790-2 | casnumber: 2235-25-8
(acetato-O)diamminephenylmercury ecnumber: 269-247-1 | casnumber: 68201-97-8
Mercury, bis(3-fluorophenyl)- ecnumber: - | casnumber: 1961-02-0
Mercury difulminate ecnumber: 211-057-8 | casnumber: 628-86-4
(Trifluoromethyl)mercuric bromide ecnumber: - | casnumber: 421-09-0
Methylmercury hydroxide ecnumber: 214-667-2 | casnumber: 1184-57-2
Mercury, (nitrate-O)(trifluoromethyl)- ecnumber: - | casnumber: 461-40-5
Dibutylrtut ecnumber: - | casnumber: 629-35-6
Chipcote ecnumber: - | casnumber: 2597-97-9
basic phenylmercury nitrate ecnumber: 620-403-0 | casnumber: 8003-05-2
Sodium timerfonate ecnumber: 227-741-4 | casnumber: 5964-24-9
Octadecanoic acid, mercury(1+) salt ecnumber: - | casnumber: 86320-46-9
2-Chloromercuri-4-nitrophenol ecnumber: - | casnumber: 24579-90-6
Sodium 4-hydroxymercuriobenzoate ecnumber: 205-340-5 | casnumber: 138-85-2
6-methyl-3-nitrobenzoxamercurete ecnumber: 205-112-5 | casnumber: 133-58-4
Phenyl(quinolin-8-olato-N1,O8)mercury ecnumber: 238-316-8 | casnumber: 14354-56-4
Mercuderamide ecnumber: 208-371-2 | casnumber: 525-30-4
(lactato-O1,O2)mercury ecnumber: 242-673-5 | casnumber: 18918-06-4
1H-Tetrazole, 5-nitro-, mercury(2+) salt ecnumber: - | casnumber: 60345-95-1
Diethylmercury ecnumber: 211-000-7 | casnumber: 627-44-1
Di-p-tolylmercury ecnumber: 208-672-9 | casnumber: 537-64-4
4-Chloromercuribenzenesulfonate ecnumber: - | casnumber: 554-77-8
Hydrogen μ-hydroxy[μ-[orthoborato(3-)-O:O']]diphenyldimercurate(1-) ecnumber: 304-637-8 | casnumber: 94277-53-9
Chloro-m-tolylmercury ecnumber: 227-722-0 | casnumber: 5955-19-1
Phenylmercury acetate ecnumber: 200-532-5 | casnumber: 62-38-4
Bis(ethylmercuri)phosphate ecnumber: - | casnumber: 2440-45-1
Dihydrogen [orthoborato(3-)-O]phenylmercurate(2-) ecnumber: 203-068-1 | casnumber: 102-98-7
(Pentafluorophenyl)mercury ecnumber: - | casnumber: 973-17-1
Mercury, hydroxy(hydroxynitrophenyl)-, monosodium salt ecnumber: - | casnumber: 1300-34-1
[μ-[(oxydiethylene phthalato)(2-)]]diphenylmercury ecnumber: 301-792-3 | casnumber: 94070-93-6
(2-carboxy-m-tolyl)hydroxymercury, monosodium salt ecnumber: 258-195-5 | casnumber: 52795-88-7
Bromophenylmercury ecnumber: 214-760-8 | casnumber: 1192-89-8
2-ethoxyethylmercury acetate ecnumber: 204-678-0 | casnumber: 124-08-3
Bis(lactato-O1,O2)mercury ecnumber: 242-667-2 | casnumber: 18917-83-4
Bis(5-oxo-L-prolinato-N1,O2)mercury ecnumber: 305-388-8 | casnumber: 94481-62-6
Amminephenylmercury(1+) acetate ecnumber: 245-006-6 | casnumber: 22450-90-4
Mercury(2+) (9Z,12Z)-octadeca-9,12-dienoate ecnumber: 231-814-6 | casnumber: 7756-49-2
N-(ethylmercurio)toluene-4-sulphonanilide ecnumber: 208-231-0 | casnumber: 517-16-8
Hydrargaphen ecnumber: 238-107-1 | casnumber: 14235-86-0
Diphenylmercury ecnumber: 209-606-1 | casnumber: 587-85-9
Bis[(trimethylsilyl)methyl]mercury ecnumber: 236-315-7 | casnumber: 13294-23-0
Mercaptomerin sodium ecnumber: 244-298-2 | casnumber: 21259-76-7
4-hydroxymercuric?phenyl sulfonic acid, sodium salt ecnumber: - | casnumber: 73548-15-9
Mercury hydrogen cyclohexanebutyrate ecnumber: 263-665-8 | casnumber: 62638-02-2
Chloro(trans-2-methoxycyclooctyl)mercury ecnumber: - | casnumber: 5185-84-2
Ethylhydroxymercury ecnumber: - | casnumber: 107-28-8
Mercurate(1-), [dodecenylbutanedioato(2-)-O']phenyl-, hydrogen ecnumber: 304-575-1 | casnumber: 94276-88-7
2-ethoxyethylmercury chloride ecnumber: 204-670-7 | casnumber: 124-01-6
Lactatophenylmercury ecnumber: 204-560-9 | casnumber: 122-64-5
Mercury(1+) trifluoroacetate ecnumber: 220-875-4 | casnumber: 2923-15-1
Naphthenic acids, mercury salts ecnumber: 215-651-8 | casnumber: 1336-96-5
(acetato-O)methylmercury ecnumber: 203-547-5 | casnumber: 108-07-6
Phenylmercury stearate ecnumber: 203-217-0 | casnumber: 104-59-6
Diiodobis(5-iodopyridin-2-amine)mercury dihydroiodide ecnumber: 264-100-8 | casnumber: 63325-16-6
(bromodichloromethyl)phenylmercury ecnumber: 221-961-4 | casnumber: 3294-58-4
p-tolylmercury chloride ecnumber: 208-716-7 | casnumber: 539-43-5
Chloro(hydroxyphenyl)mercury ecnumber: 215-308-2 | casnumber: 1320-80-5
Hydroxymercury nitrile ecnumber: - | casnumber: 31065-88-0
Phenylmercury dimethyldithiocarbamate ecnumber: 251-026-6 | casnumber: 32407-99-1
Mercury, (acetato-O)(methylphenyl)- ecnumber: - | casnumber: 1300-78-3
Chloropropylmercury ecnumber: - | casnumber: 2440-40-6
Mercury, chloropyridinyl- ecnumber: - | casnumber: 1334-75-4
2-Acetoxymercurio-4-nitrophenol ecnumber: - | casnumber: 63468-53-1
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Acute Tox. 2; Acute Tox. 1; STOT RE 2

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