EU-IMPLANTABLE_MEDICAL_DEVICES-ART_3_ANX_1

Active Implantable Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 90/385/EEC on Active Implantable Medical Devices, 20 July 1990, amended by Directive 2007/47/EC, 21 September 2007

This list contains hazardous substances for purposes of Directive 90/385/EEC on active implantable medical devices, particularly as regards Article 3 and Annex I (Essential Requirements). This non-exhaustive database is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list). Please note that Regulation (EU) 2017/745 on medical devices has repealed Directive 90/385/EEC and begun to apply from 26 May 2021. Nevertheless, Article 120 of the Regulation provides for a transitional period allowing medical devices, under specified conditions (e.g., placed on the market prior to 26 May 2021), to continue to comply with the Directive. In accordance with the fourth paragraph of Article 120, this period ends 26 May 2025.

Last updated 26 October 2021. Database contains 4812 unique substances/entries.
Filter the list

423-230-7
56552-15-9
Eye Dam. 1
204-358-0
119-93-7
Carc. 1B; Acute Tox. 4
209-218-2
561-41-1
yes
202-027-5
90-94-8
Carc. 1B; Muta. 2; Eye Dam. 1
yes
418-770-5
151882-81-4
Carc. 2
207-762-5
492-80-8
Carc. 2; Acute Tox. 4; Eye Irrit. 2
407-590-2
43151-99-1
Acute Tox. 3; STOT RE 2; Skin Sens. 1
202-974-4
101-77-9
Carc. 1B; Muta. 2; STOT SE 1; STOT RE 2; Skin Sens. 1
yes
405-740-1
47073-92-7
Acute Tox. 4; STOT RE 2; Eye Dam. 1
420-530-1
-
Resp. Sens. 1; Skin Sens. 1
405-790-4
101657-77-6
Skin Sens. 1
243-420-1
19900-65-3
Carc. 2; Acute Tox. 4
415-150-6
16298-38-7
STOT RE 2
412-840-9
13474-64-1
Acute Tox. 4; STOT RE 2; Skin Corr. 1A
225-863-2
5124-30-1
Acute Tox. 3; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1; Skin Sens. 1
212-658-8
838-88-0
Carc. 1B; Acute Tox. 4; Skin Sens. 1
yes
202-966-0
101-68-8
Carc. 2; Acute Tox. 4; STOT RE 2; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1; Skin Sens. 1
431-850-4
7456-68-0
Expl. 1.1; STOT RE 2
404-590-4
90884-29-0
Skin Sens. 1
-
-
Carc. 1B; Muta. 1B; Repr. 2; Acute Tox. 3
yes
202-977-0
101-80-4
Carc. 1B; Muta. 1B; Repr. 2; Acute Tox. 3
yes
403-330-7
24197-34-0
Eye Dam. 1
-
-
Carc. 1B; Acute Tox. 4
205-370-9
139-65-1
Carc. 1B; Acute Tox. 4
421-360-9
148043-73-6
Acute Tox. 4
404-060-2
22432-68-4
Acute Tox. 2; Acute Tox. 4; Skin Corr. 1B
407-690-6
19060-15-2
Acute Tox. 4; Skin Corr. 1B; Skin Sens. 1
421-750-9
57280-22-5
Eye Irrit. 2; Skin Sens. 1
401-720-1
6807-17-6
Repr. 1B; Eye Irrit. 2
yes
264-843-8
64359-81-5
Acute Tox. 2; Acute Tox. 4; Skin Corr. 1; Eye Dam. 1; Skin Sens. 1A
403-000-2
91853-67-7
Skin Irrit. 2
-
-
Acute Tox. 4; Skin Irrit. 2; Skin Sens. 1
-
-
yes
-
2315-61-9
yes
205-426-2
140-66-9
Skin Irrit. 2; Eye Dam. 1
yes
423-860-2
56309-94-5
Skin Sens. 1
257-907-1
52427-13-1
yes
ACRYLOYLMORPHOLIN
418-140-1
5117-12-4
Acute Tox. 4; STOT RE 2; Eye Dam. 1; Skin Sens. 1
-
521947-27-3
yes
402-190-4
113674-95-6
STOT RE 1; Acute Tox. 4; STOT RE 2; Eye Dam. 1; Skin Sens. 1
413-510-7
147374-67-2
STOT RE 2; Skin Sens. 1
429-000-2
159235-16-2
Skin Sens. 1
-
-
yes
272-233-8
68784-25-8
yes
410-600-8
124719-26-2
STOT RE 2; Skin Irrit. 2
635-389-1
186825-36-5
yes
635-391-2
142731-63-3
yes
635-696-0
186825-39-8
yes
413-120-7
107144-30-9
Acute Tox. 4
250-863-4
31906-04-4
Skin Sens. 1A

export-type