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Annex III inventory

Annex III inventory

ECHA compiled an inventory of substances likely to meet the criteria of Annex III to the REACH Regulation. The aim is to support registrants in identifying whether reduced minimum information requirements or a full Annex VII information set is required.

The inventory was produced using publicly available databases with experimental data and by using (Q)SAR model results. Indications for hazardous toxicological or ecotoxicological properties together with information on uses and other available relevant information have to be compared with the criteria in Annex III.

The fact that a substance is not in this list does not necessarily mean that the criteria for Annex III are not met. Likewise, if a substance is on this inventory, a registrant can still benefit from the reduced information requirements if it is justified.

Note that the inventory is not a tool for classification, it only shows indications for concern. For instance, the fact that a substance is indicated as "Suspected mutagen" does not mean that ECHA considers it as a classified mutagen. All evidence should be taken into account before concluding on the need for classification.

Download the full Annex III Inventory

You can download the full Annex III inventory as XLS format.

Download Annex III Inventory

 

Last updated 06 April 2021. Database contains 64899 unique substances/entries.
Filter the list

 
259-178-5
54476-55-0
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected toxic for reproduction
Details
208-717-2
539-44-6
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected respiratory sensitiser
Suspected toxic for reproduction
Details
279-190-4
79574-98-4
Suspected acutely toxic via the oral route
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
220-963-2
2947-61-7
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
210-738-7
622-47-9
Suspected acutely toxic via the oral route
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
203-173-2
104-09-6
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
267-504-2
67874-76-4
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected respiratory sensitiser
Suspected skin sensitiser
Suspected toxic for reproduction
Details
210-144-8
607-88-5
Suspected acutely toxic via the oral route
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
231-347-8
7495-84-3
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected respiratory sensitiser
Suspected skin sensitiser
Suspected toxic for reproduction
Details
202-990-1
101-94-0
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected respiratory sensitiser
Suspected skin sensitiser
Suspected toxic for reproduction
Details
261-803-1
59558-23-5
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected respiratory sensitiser
Suspected skin sensitiser
Suspected toxic for reproduction
Details
238-977-2
14908-64-6
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected respiratory sensitiser
Suspected skin irritant
Suspected skin sensitiser
Suspected toxic for reproduction
Details
233-024-7
10024-57-4
Suspected hazardous to the aquatic environment
Suspected respiratory sensitiser
Suspected skin sensitiser
Suspected toxic for reproduction
Details
259-465-5
55066-56-3
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected respiratory sensitiser
Suspected skin sensitiser
Suspected toxic for reproduction
Details
210-745-5
622-59-3
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
203-159-6
103-93-5
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected respiratory sensitiser
Suspected skin sensitiser
Suspected toxic for reproduction
Details
268-832-9
68141-11-7
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected respiratory sensitiser
Suspected skin sensitiser
Suspected toxic for reproduction
Details
213-332-8
937-62-2
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin irritant
Suspected skin sensitiser
Suspected toxic for reproduction
Details
238-654-6
14617-92-6
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected respiratory sensitiser
Suspected skin sensitiser
Suspected toxic for reproduction
Details
210-380-1
614-34-6
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
205-413-1
140-39-6
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected respiratory sensitiser
Suspected skin sensitiser
Suspected toxic for reproduction
Details
279-451-2
80370-33-8
Suspected carcinogen
Suspected mutagen
Suspected skin sensitiser
Suspected toxic for reproduction
Details
267-164-5
67801-43-8
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected respiratory sensitiser
Suspected skin sensitiser
Suspected toxic for reproduction
Details
246-422-0
24700-20-7
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
267-892-3
67952-39-0
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected respiratory sensitiser
Suspected skin sensitiser
Suspected toxic for reproduction
Details
212-864-8
874-60-2
Suspected acutely toxic via the oral route
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin irritant
Suspected skin sensitiser
Suspected toxic for reproduction
Details
222-815-2
3619-22-5
Suspected acutely toxic via the oral route
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected respiratory sensitiser
Suspected toxic for reproduction
Details
208-741-3
540-25-0
Suspected acutely toxic via the oral route
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for carcinogenicity
Harmonised classification for eye irritation
Harmonised classification for skin sensitisation
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin irritant
Suspected skin sensitiser
Suspected toxic for reproduction
Details
202-803-3
99-94-5
Suspected hazardous to the aquatic environment
Suspected toxic for reproduction
Details
207-238-6
455-16-3
Suspected toxic for reproduction
Details
242-849-1
19158-51-1
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
253-852-2
38258-26-3
Suspected mutagen
Suspected toxic for reproduction
Details
210-600-6
619-55-6
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected toxic for reproduction
Details
203-246-9
104-87-0
Suspected acutely toxic via the oral route
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected toxic for reproduction
Details
221-288-6
3056-64-2
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected respiratory sensitiser
Suspected skin sensitiser
Suspected toxic for reproduction
Details
241-305-0
17269-94-2
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
267-429-5
67859-80-7
Suspected toxic for reproduction
Details
212-215-9
769-92-6
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
213-399-3
943-27-1
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
237-014-3
13586-68-0
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin irritant
Suspected skin sensitiser
Suspected toxic for reproduction
Details
229-483-8
6554-98-9
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
248-330-6
27214-47-7
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin irritant
Suspected skin sensitiser
Suspected toxic for reproduction
Details
284-999-0
85005-66-9
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
211-446-2
645-56-7
Suspected acutely toxic via the oral route
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin irritant
Suspected skin sensitiser
Suspected toxic for reproduction
Details
235-888-0
13026-23-8
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected toxic for reproduction
Details
216-944-3
1706-12-3
Suspected acutely toxic via the oral route
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
218-682-5
2215-77-2
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
253-932-7
38444-13-2
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
217-302-5
1806-26-4
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin irritant
Suspected skin sensitiser
Suspected toxic for reproduction
Details
222-692-5
3575-31-3
Suspected hazardous to the aquatic environment
Suspected skin irritant
Suspected skin sensitiser
Suspected toxic for reproduction
Details
251-944-7
34332-96-2
Suspected persistent in the environment
Suspected skin irritant
Suspected toxic for reproduction
Details
203-199-4
104-40-5
Suspected bioaccumulative
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin irritant
Suspected skin sensitiser
Suspected toxic for reproduction
Details
223-653-5
4003-94-5
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
210-771-7
623-11-0
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
254-515-2
39565-05-4
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
238-653-0
14617-85-7
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected respiratory sensitiser
Suspected skin sensitiser
Suspected toxic for reproduction
Details
256-924-1
51031-70-0
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected respiratory sensitiser
Suspected skin sensitiser
Suspected toxic for reproduction
Details
203-193-1
104-30-3
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
217-326-6
1817-47-6
Suspected acutely toxic via the oral route
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
210-617-9
619-89-6
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
217-076-8
1734-79-8
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
236-299-1
13287-49-5
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
210-618-4
619-90-9
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
258-035-4
52602-94-5
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected respiratory sensitiser
Suspected skin sensitiser
Suspected toxic for reproduction
Details
249-454-3
29124-83-2
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected respiratory sensitiser
Suspected skin sensitiser
Suspected toxic for reproduction
Details
258-580-8
53483-70-8
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected respiratory sensitiser
Suspected skin sensitiser
Suspected toxic for reproduction
Details
258-910-0
53994-83-5
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected respiratory sensitiser
Suspected skin sensitiser
Suspected toxic for reproduction
Details
211-271-1
636-97-5
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected respiratory sensitiser
Suspected toxic for reproduction
Details
286-352-8
85223-00-3
Suspected carcinogen
Suspected mutagen
Suspected toxic for reproduction
Details
268-721-5
68133-98-2
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected toxic for reproduction
Details
224-199-0
4238-41-9
Suspected carcinogen
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
226-267-5
5337-93-9
Suspected acutely toxic via the oral route
Suspected hazardous to the aquatic environment
Suspected toxic for reproduction
Details
221-865-2
3261-62-9
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin irritant
Suspected skin sensitiser
Suspected toxic for reproduction
Details
245-056-9
22532-47-4
Suspected hazardous to the aquatic environment
Suspected toxic for reproduction
Details
249-024-5
28446-70-0
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected toxic for reproduction
Details
253-921-7
38418-10-9
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
219-396-3
2431-00-7
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
258-107-5
52693-87-5
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected toxic for reproduction
Details
284-185-5
84803-58-7
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin irritant
Suspected toxic for reproduction
Details
228-496-6
6282-37-7
Suspected hazardous to the aquatic environment
Suspected toxic for reproduction
Details
212-693-9
847-83-6
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
214-530-7
1142-15-0
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
200-245-5
55-81-2
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected skin sensitiser
Suspected toxic for reproduction
Details
243-854-1
20498-67-3
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected toxic for reproduction
Details
222-265-3
3398-68-3
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
244-917-6
22331-70-0
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
254-582-8
39668-86-5
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin irritant
Suspected skin sensitiser
Suspected toxic for reproduction
Details
201-287-7
80-52-4
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin irritant
Suspected skin sensitiser
Suspected toxic for reproduction
Details
233-944-9
10458-14-7
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
202-757-4
99-48-9
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
210-575-1
619-01-2
Suspected hazardous to the aquatic environment
Suspected skin irritant
Suspected skin sensitiser
Suspected toxic for reproduction
Details
201-943-2
89-82-7
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
237-548-7
13835-75-1
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
233-986-8
10482-56-1
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin irritant
Suspected skin sensitiser
Suspected toxic for reproduction
Details
209-235-5
562-74-3
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
202-798-8
99-89-8
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin irritant
Suspected skin sensitiser
Suspected toxic for reproduction
Details
233-235-4
10099-57-7
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
222-138-2
3368-21-6
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
230-230-9
6975-24-2
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected skin irritant
Suspected skin sensitiser
Suspected toxic for reproduction
Details
266-814-5
67634-10-0
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details

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