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Annex III inventory

Annex III inventory

ECHA compiled an inventory of substances likely to meet the criteria of Annex III to the REACH Regulation. The aim is to support registrants in identifying whether reduced minimum information requirements or a full Annex VII information set is required.

The inventory was produced using publicly available databases with experimental data and by using (Q)SAR model results. Indications for hazardous toxicological or ecotoxicological properties together with information on uses and other available relevant information have to be compared with the criteria in Annex III.

The fact that a substance is not in this list does not necessarily mean that the criteria for Annex III are not met. Likewise, if a substance is on this inventory, a registrant can still benefit from the reduced information requirements if it is justified.

Note that the inventory is not a tool for classification, it only shows indications for concern. For instance, the fact that a substance is indicated as "Suspected mutagen" does not mean that ECHA considers it as a classified mutagen. All evidence should be taken into account before concluding on the need for classification.

Download the full Annex III Inventory

You can download the full Annex III inventory as XLS format.

Download Annex III Inventory

 

Last updated 06 April 2021. Database contains 64899 unique substances/entries.
Filter the list

 
603-036-0
125-14-4
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
607-209-1
2320-38-9
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
613-264-2
6358-99-2
Suspected skin sensitiser
Suspected toxic for reproduction
Details
275-887-2
71720-39-3
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected toxic for reproduction
Details
606-207-8
190330-15-5
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
238-448-6
14458-75-4
Suspected mutagen
Suspected persistent in the environment
Details
601-221-0
1130-20-7
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
251-134-3
32638-88-3
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected respiratory sensitiser
Suspected skin sensitiser
Suspected toxic for reproduction
Details
610-259-7
455264-97-8
Suspected hazardous to the aquatic environment
Suspected toxic for reproduction
Details
601-320-9
114747-44-3
Suspected mutagen
Suspected persistent in the environment
Details
601-321-4
114747-45-4
Suspected mutagen
Suspected persistent in the environment
Details
266-679-2
67392-87-4
Suspected bioaccumulative
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
205-873-3
182-55-8
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Details
209-880-2
596-24-7
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
205-629-6
144-45-6
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Details
212-024-0
749-02-0
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected toxic for reproduction
Details
620-407-2
131929-63-0
Harmonised classification for aquatic toxicity
Details
620-162-1
131929-60-7
Harmonised classification for aquatic toxicity
Details
246-298-8
24527-27-3
Suspected carcinogen
Suspected persistent in the environment
Details
247-385-3
25978-54-5
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin irritant
Suspected skin sensitiser
Details
245-578-7
23312-56-3
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected toxic for reproduction
Details
244-554-3
21736-83-4
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected toxic for reproduction
Details
216-911-3
1695-77-8
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected toxic for reproduction
Details
206-078-4
299-39-8
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
201-988-8
90-39-1
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
614-280-2
68122-66-7
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Details
263-222-9
61792-47-0
Suspected carcinogen
Suspected hazardous to the aquatic environment
Details
282-710-2
84309-53-5
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Details
300-841-6
93963-95-2
Suspected carcinogen
Suspected hazardous to the aquatic environment
Details
302-698-5
94131-37-0
Suspected hazardous to the aquatic environment
Details
259-141-3
54392-27-7
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Details
301-037-8
93980-59-7
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Details
299-750-1
93894-51-0
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Details
301-776-6
94043-07-9
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Details
262-958-8
61752-68-9
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Details
300-839-5
93963-93-0
Suspected carcinogen
Suspected hazardous to the aquatic environment
Details
260-306-7
56645-05-7
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Details
263-834-6
63059-79-0
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Details
262-098-3
60177-36-8
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Details
616-298-6
76169-00-1
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected skin sensitiser
Suspected toxic for reproduction
Details
307-398-8
97635-38-6
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
263-600-3
62568-11-0
Suspected hazardous to the aquatic environment
Details
300-842-1
93963-96-3
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected skin sensitiser
Details
282-711-8
84309-54-6
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Details
276-106-8
71872-97-4
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Details
300-837-4
93963-92-9
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Details
618-569-4
9050-57-1
Suspected carcinogen
Suspected toxic for reproduction
Details
301-035-7
93980-57-5
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected skin sensitiser
Details
300-840-0
93963-94-1
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected skin sensitiser
Suspected toxic for reproduction
Details
276-107-3
71872-98-5
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
256-775-2
50809-53-5
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected skin sensitiser
Details
308-166-9
97889-88-8
Suspected hazardous to the aquatic environment
Details
253-084-8
36521-89-8
Suspected hazardous to the aquatic environment
Details
269-410-7
68238-87-9
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Details
275-722-4
71617-69-1
Suspected hazardous to the aquatic environment
Details
249-302-6
28905-44-4
Suspected hazardous to the aquatic environment
Details
301-036-2
93980-58-6
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Details
249-448-0
29116-98-1
Suspected hazardous to the aquatic environment
Details
299-742-8
93894-44-1
Suspected hazardous to the aquatic environment
Details
299-743-3
93894-45-2
Suspected carcinogen
Suspected hazardous to the aquatic environment
Details
300-843-7
93963-97-4
Suspected hazardous to the aquatic environment
Details
235-671-0
12441-09-7
Suspected skin sensitiser
Details
254-186-5
38916-34-6
Suspected persistent in the environment
Suspected skin sensitiser
Details
A complex combination of hydrocarbons obtained by treating a petroleum fraction with hydrogen in the presence of a catalyst. It consists predominantly of aromatic hydrocarbons having carbon numbers predominantly in the range of C8 through C10 and boiling in the range of approximately 135°C to 210°C(275°F to 410°F).
270-988-8
68512-78-7
Harmonised classification for aspiration toxicity
Harmonised classification for carcinogenicity
Harmonised classification for mutagenicity
Details
A complex combination of hydrocarbons obtained by treating a petroleum fraction with hydrogen in the presence of a catalyst. It consists predominantly of cycloparaffinic hydrocarbons having carbon numbers predominantly in the range of C6 through C7 and boiling in the range of approximately 73°C to 85°C (163°F to 185°F).
295-529-9
92062-15-2
Harmonised classification for aspiration toxicity
Harmonised classification for carcinogenicity
Harmonised classification for mutagenicity
Details
A complex combination of hydrocarbons obtained by the catalytic hydrodesulfurization of a petroleum fraction. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C10 through C13 and boiling in the range of approximately 175°C to 220°C (347°F to 428°F).
309-884-5
101316-82-9
Harmonised classification for aspiration toxicity
Details
A complex combination of hydrocarbons obtained by the catalytic hydrodesulfurization of a petroleum fraction. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C10 through C13 and boiling in the range of approximately 180°C to 240°C (356°F to 464°F).
309-882-4
101316-81-8
Harmonised classification for aspiration toxicity
Details
287-498-5
85536-17-0
Harmonised classification for carcinogenicity
Harmonised classification for mutagenicity
Details
287-500-4
85536-19-2
Harmonised classification for carcinogenicity
Harmonised classification for mutagenicity
Details
205-116-7
133-65-3
Suspected mutagen
Suspected persistent in the environment
Details
204-774-2
126-17-0
Suspected bioaccumulative
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected toxic for reproduction
Details
201-309-5
80-78-4
Suspected bioaccumulative
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected toxic for reproduction
Details
207-478-1
474-08-8
Suspected bioaccumulative
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected toxic for reproduction
Details
225-973-0
5189-62-8
Suspected bioaccumulative
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected toxic for reproduction
Details
616-081-6
743423-33-8
Suspected carcinogen
Suspected mutagen
Details
608-818-5
32997-86-7
Suspected mutagen
Details
692-557-7
164579-32-2
Suspected carcinogen
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Details
261-511-4
58946-33-1
Suspected carcinogen
Suspected hazardous to the aquatic environment
Details
257-242-7
51498-24-9
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Details
270-584-1
68444-12-2
Suspected persistent in the environment
Suspected toxic for reproduction
Details
253-556-3
37589-10-9
Suspected carcinogen
Suspected hazardous to the aquatic environment
Details
243-023-3
19395-79-0
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
250-898-5
32014-22-5
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin irritant
Suspected skin sensitiser
Details
262-406-6
60758-21-6
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin irritant
Suspected toxic for reproduction
Details
256-537-8
50316-92-2
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Details
276-635-4
72391-24-3
Suspected carcinogen
Suspected mutagen
Suspected persistent in the environment
Suspected respiratory sensitiser
Suspected skin sensitiser
Details
274-472-3
70236-38-3
Suspected carcinogen
Suspected mutagen
Suspected persistent in the environment
Suspected respiratory sensitiser
Suspected skin sensitiser
Suspected toxic for reproduction
Details
252-169-7
34722-90-2
Suspected carcinogen
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
263-653-2
62625-28-9
Suspected carcinogen
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Details
263-657-4
62625-32-5
Suspected carcinogen
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Details
271-304-0
68540-43-2
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin irritant
Suspected skin sensitiser
Suspected toxic for reproduction
Details
253-009-9
36389-86-3
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Details
213-961-8
1069-66-5
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected skin sensitiser
Suspected toxic for reproduction
Details
228-064-7
6106-41-8
Suspected hazardous to the aquatic environment
Suspected skin irritant
Suspected skin sensitiser
Suspected toxic for reproduction
Details
248-583-2
27636-75-5
Suspected persistent in the environment
Suspected skin irritant
Suspected skin sensitiser
Details
214-004-7
1072-24-8
Suspected acutely toxic via the oral route
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Details
241-301-9
17265-30-4
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Details
220-881-7
2923-26-4
Suspected carcinogen
Suspected persistent in the environment
Details
222-264-8
3398-33-2
Suspected hazardous to the aquatic environment
Suspected skin irritant
Suspected skin sensitiser
Details
230-653-9
7246-21-1
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected toxic for reproduction
Details

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