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Annex III inventory

Annex III inventory

ECHA compiled an inventory of substances likely to meet the criteria of Annex III to the REACH Regulation. The aim is to support registrants in identifying whether reduced minimum information requirements or a full Annex VII information set is required.

The inventory was produced using publicly available databases with experimental data and by using (Q)SAR model results. Indications for hazardous toxicological or ecotoxicological properties together with information on uses and other available relevant information have to be compared with the criteria in Annex III.

The fact that a substance is not in this list does not necessarily mean that the criteria for Annex III are not met. Likewise, if a substance is on this inventory, a registrant can still benefit from the reduced information requirements if it is justified.

Note that the inventory is not a tool for classification, it only shows indications for concern. For instance, the fact that a substance is indicated as "Suspected mutagen" does not mean that ECHA considers it as a classified mutagen. All evidence should be taken into account before concluding on the need for classification.

Download the full Annex III Inventory

You can download the full Annex III inventory as XLS format.

Download Annex III Inventory

 

Last updated 06 April 2021. Database contains 64899 unique substances/entries.
Filter the list

 
245-496-1
23215-04-5
Suspected carcinogen
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Details
265-318-6
65036-65-9
Suspected carcinogen
Suspected mutagen
Suspected persistent in the environment
Suspected skin irritant
Suspected skin sensitiser
Details
275-807-6
71662-40-3
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Details
209-290-5
565-73-1
Suspected carcinogen
Suspected skin sensitiser
Details
205-591-0
143-19-1
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Details
226-195-4
5324-84-5
Suspected mutagen
Suspected persistent in the environment
Suspected skin irritant
Suspected toxic for reproduction
Details
214-295-0
1120-04-3
Suspected persistent in the environment
Suspected skin sensitiser
Details
262-763-8
61392-14-1
Suspected toxic for reproduction
Details
223-781-1
4070-80-8
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Details
265-560-2
65151-89-5
Suspected persistent in the environment
Suspected skin sensitiser
Details
248-866-0
28141-42-6
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected toxic for reproduction
Details
254-270-1
39068-23-0
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin irritant
Suspected skin sensitiser
Suspected toxic for reproduction
Details
239-219-3
15163-46-9
Suspected persistent in the environment
Suspected skin irritant
Suspected skin sensitiser
Details
224-914-6
4549-72-8
Suspected hazardous to the aquatic environment
Suspected skin irritant
Suspected skin sensitiser
Details
269-945-6
68391-33-3
Suspected carcinogen
Suspected persistent in the environment
Details
231-461-8
7563-58-8
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin irritant
Details
207-777-7
493-53-8
Suspected acutely toxic via the oral route
Suspected hazardous to the aquatic environment
Suspected respiratory sensitiser
Suspected skin sensitiser
Details
247-356-5
25942-40-9
Suspected mutagen
Suspected persistent in the environment
Suspected toxic for reproduction
Details
245-875-1
23778-59-8
Suspected mutagen
Suspected persistent in the environment
Suspected respiratory sensitiser
Suspected toxic for reproduction
Details
272-129-2
68739-07-1
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Details
255-487-4
41670-36-4
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Details
216-080-7
1491-91-4
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Details
247-636-7
26377-29-7
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Details
248-322-2
27205-99-8
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Details
251-579-3
33581-25-8
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin irritant
Details
251-598-7
33619-92-0
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Details
261-176-4
58237-07-3
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin irritant
Details
259-017-9
54181-64-5
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin irritant
Suspected skin sensitiser
Suspected toxic for reproduction
Details
302-337-1
94108-00-6
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Details
237-887-0
14047-60-0
Suspected hazardous to the aquatic environment
Suspected skin irritant
Suspected skin sensitiser
Details
249-100-8
28605-72-3
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected toxic for reproduction
Details
250-692-5
31548-27-3
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Details
220-171-7
2650-44-4
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Details
215-323-4
1321-69-3
Suspected mutagen
Suspected persistent in the environment
Suspected skin irritant
Details
208-523-8
532-02-5
Suspected mutagen
Suspected persistent in the environment
Suspected skin irritant
Details
204-976-0
130-14-3
Suspected mutagen
Suspected persistent in the environment
Suspected skin irritant
Details
200-504-2
61-31-4
Suspected acutely toxic via the oral route
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
228-054-2
6102-28-9
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Details
261-411-0
58725-55-6
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Details
228-165-6
6152-67-6
Suspected mutagen
Suspected persistent in the environment
Details
233-605-5
10265-69-7
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Details
261-408-4
58725-46-5
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Details
238-322-0
14356-62-8
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Details
242-576-8
18791-25-8
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Details
257-056-6
51206-97-4
Suspected hazardous to the aquatic environment
Suspected toxic for reproduction
Details
250-151-3
30364-51-3
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Details
244-430-9
21539-72-0
Suspected hazardous to the aquatic environment
Suspected skin irritant
Suspected skin sensitiser
Details
225-888-9
5136-55-0
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Details
244-429-3
21539-58-2
Suspected hazardous to the aquatic environment
Suspected skin irritant
Suspected skin sensitiser
Details
287-873-3
85586-68-1
Suspected hazardous to the aquatic environment
Suspected skin irritant
Details
271-446-3
68555-69-1
Suspected carcinogen
Suspected persistent in the environment
Details
271-447-9
68555-70-4
Suspected bioaccumulative
Suspected carcinogen
Suspected persistent in the environment
Details
271-448-4
68555-71-5
Suspected bioaccumulative
Suspected carcinogen
Suspected persistent in the environment
Details
223-391-1
3871-50-9
Suspected carcinogen
Details
222-597-9
3546-96-1
Suspected hazardous to the aquatic environment
Suspected skin irritant
Suspected skin sensitiser
Details
231-553-8
7631-98-3
Suspected hazardous to the aquatic environment
Suspected skin irritant
Suspected skin sensitiser
Details
250-995-2
32339-03-0
Suspected persistent in the environment
Suspected skin irritant
Details
227-909-7
6034-54-4
Suspected persistent in the environment
Details
243-143-6
19542-74-6
Suspected mutagen
Suspected respiratory sensitiser
Suspected skin sensitiser
Details
263-497-5
62307-74-8
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected toxic for reproduction
Details
276-556-5
72269-59-1
Suspected carcinogen
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Details
262-794-7
61438-64-0
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Details
239-495-5
15475-56-6
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected toxic for reproduction
Details
262-276-0
60520-46-9
Suspected acutely toxic via the oral route
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Details
301-894-8
94087-03-3
Suspected hazardous to the aquatic environment
Suspected skin irritant
Suspected skin sensitiser
Details
301-628-0
94023-30-0
Suspected hazardous to the aquatic environment
Suspected skin irritant
Suspected skin sensitiser
Details
278-597-4
77056-22-5
Suspected hazardous to the aquatic environment
Suspected skin irritant
Suspected skin sensitiser
Details
301-895-3
94087-04-4
Suspected hazardous to the aquatic environment
Suspected skin irritant
Suspected skin sensitiser
Details
248-275-8
27159-90-6
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
230-678-5
7257-44-5
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected toxic for reproduction
Details
278-979-0
78739-59-0
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
260-483-0
56968-08-2
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Details
271-468-3
68556-01-4
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
255-596-7
41945-48-6
Suspected mutagen
Suspected persistent in the environment
Details
274-357-8
70161-44-3
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Details
279-582-5
80866-78-0
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Details
298-453-4
93804-76-3
Suspected hazardous to the aquatic environment
Suspected skin irritant
Suspected skin sensitiser
Details
219-928-4
2577-32-4
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected toxic for reproduction
Details
245-553-0
23282-55-5
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected toxic for reproduction
Details
245-571-9
23307-72-4
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected toxic for reproduction
Details
224-939-2
4563-84-2
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected toxic for reproduction
Details
275-888-8
71720-40-6
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected toxic for reproduction
Details
271-322-9
68540-87-4
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
268-191-5
68025-33-2
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
271-474-6
68556-12-7
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
223-004-6
3691-68-7
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected toxic for reproduction
Details
271-321-3
68540-86-3
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
271-475-1
68556-13-8
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
300-876-7
93964-27-3
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
260-002-4
56116-64-4
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Details
271-469-9
68556-04-7
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
300-872-5
93964-23-9
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
300-875-1
93964-26-2
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Details
306-834-4
97416-86-9
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
212-730-9
863-57-0
Suspected persistent in the environment
Suspected toxic for reproduction
Details
304-962-5
94313-64-1
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected toxic for reproduction
Details
281-722-5
84029-49-2
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Details
218-607-6
2200-44-4
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected toxic for reproduction
Details
266-486-3
66810-88-6
Suspected hazardous to the aquatic environment
Suspected skin irritant
Suspected skin sensitiser
Details
264-311-5
63556-21-8
Suspected hazardous to the aquatic environment
Suspected skin irritant
Suspected skin sensitiser
Details

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