Summary of Classification and Labelling
Harmonised classification - Annex VI of Regulation (EC) No 1272/2008 (CLP Regulation)
General Information
Index Number EC / List no.

EC: European Community number/ List no.: List number assigned by ECHA.

List Numbers are purely technical identifiers for processing a submission via REACH-IT. More information: https://echa.europa.eu/information-on-chemicals/registered-substances/information

CAS Number International Chemical Identification
603-023-00-X 200-849-9 75-21-8 ethylene oxide
oxirane

ATP Inserted / Updated: CLP00/ATP01corr This field indicates when an entry in Annex VI to CLP has been inserted and/or updated with an Adaptation to Technical Progress (ATP) to the CLP Regulation.
CLP Classification (Table 3)
Classification Labelling Specific Concentration limits, M-Factors, Acute Toxicity Estimates (ATE) Notes
Hazard Class and Category Code(s) Hazard Statement Code(s) Hazard Statement Code(s) Supplementary Hazard Statement Code(s) Pictograms, Signal Word Code(s)
Press. Gas GHS02
GHS08
GHS04
GHS06
Dgr
Note U
Flam. Gas 1 H220 H220
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 * H331 H331
STOT SE 3 H335 H335
Muta. 1B H340 H340
Carc. 1B H350 H350

Signal Words Pictograms
Danger
GHS02
Flame
GHS08
Health hazard
GHS04
Gas cylinder
GHS06
Skull and crossbones
Seveso III Data
Disclaimer: Please note that some of the substances covered by the Seveso Directive can belong to more than one Seveso categories. It will be up to the users to decide whether their substance or mixture fall in one or in more of these classification categories depending on the tonnage bands and the concentrations.
Please also note that ECHA is not an authority for the Seveso Directive and that the Seveso categorisation below is provided for information only. The Seveso III Directive (Directive 2012/18/EU repealing Directive 96/82/EC (Seveso II) from 1 June 2015) is the only authentic legal reference and that the information in this inventory does not constitute legal advice. For further information on Seveso, please ask your national authority.

Seveso Data
Seveso Substance Seveso Categories
Yes Named
P2
Notified classification and labelling
General Information
EC / List no.

EC: European Community number/ List no.: List number assigned by ECHA.

List Numbers are purely technical identifiers for processing a submission via REACH-IT. More information: https://echa.europa.eu/information-on-chemicals/registered-substances/information

Name CAS Number
The CAS number associated with this substance in the EC Inventory and/or REACH-IT is reported here. In some cases, e.g. for differently hydrated forms of the same substance, alternative CAS numbers have been notified. In those cases, the additional CAS numbers are published in the column “additional notified information” below.
200-849-9 Ethylene oxide 75-21-8

Notified classification and labelling according to CLP criteria
Classification Labelling Specific Concentration limits, M-Factors Notes Classification affected by Impurities / Additives

This check appears when a notifier has indicated that an impurity or an additive present in the substance impacts the notified classification. ECHA cannot reveal the identity of the impurity/additive or determine the exact impact it has on the classification.

Additional Notified Information

State/form: The notified state/form of the substance for all notifications classifying in this manner is reported under this link. Additional CAS number(s): Occasionally, a notification contains a different CAS number than the one reported under the general information section above. In those cases, all different notified CAS numbers associated with the aggregated classification are reported under this link. IUPAC name(s): Publicly available IUPAC names from all notifications classifying in this manner are reported under this link.

Number of Notifiers

This number indicates how many companies notified this classification. All members of a REACH registration joint submission and all participants in a group of manufacturers/importers who notified are counted. The grouping is done automatically with no manual verification.

Joint Entries

This check appears when a classification comes from a lead dossier of a REACH registration joint submission. When a member submits a classification separately under Article 11(3) of REACH (opt-out), this classification is displayed separately and not marked as a joint entry.

Hazard Class and Category Code(s) Hazard Statement Code(s) Hazard Statement Code(s) Supplementary Hazard Statement Code(s) Pictograms, Signal Word Code(s)
  H220 GHS02
GHS08
GHS05
GHS04
GHS06
Dgr
474 yes View details
Flam. Gas 1, Chem. Unst. Gas A H220,H230  
  H230
Press. Gas (Liq.) H280 H280
Acute Tox. 3 H301 H301
Skin Corr. 1 H314 H314
Eye Dam. 1 H318 H318
Acute Tox. 3 H331 H331
STOT SE 3 H335 (respiratory tra...) H335
STOT SE 3 H336 (nervous system) H336
Muta. 1B H340 H340
Carc. 1B H350 H350
Repr. 1B H360 (fertility and d...) H360 (H360Fd)
STOT RE 1 H372 (nervous system) H372
Flam. Gas 1 H220 H220 GHS02
GHS08
GHS06
GHS04
Dgr
State/Form
2120 View details
H280 H280
Acute Tox. 4 H302 H302
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 (Respiratory sys...) H335
Muta. 1B H340 (Inhalation) H340
Carc. 1B H350 (Inhalation) H350
STOT RE 1 H372 (Nervous system) H372
Flam. Gas 1 H220 H220 GHS02
GHS08
GHS04
GHS06
Dgr
State/Form
338 View details
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 H335
Muta. 1B H340 H340
Carc. 1B H350 H350
Flam. Gas 1 H220 H220 GHS02
GHS08
GHS06
GHS04
Dgr
90 View details
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 (not specified) H335
Muta. 1B H340 H340
Carc. 1B H350 H350
Flam. Gas 1 H220 H220 EUH006
GHS02
GHS08
GHS06
GHS04
Dgr
Note U
State/Form
71 View details
H280 H280
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 (Respiratory tra...) H335
Muta. 1B H340 H340
Carc. 1B H350 H350
Flam. Gas 1 H220 H220 GHS02
GHS08
GHS06
GHS04
Dgr
State/Form
71 View details
H280 H280
Acute Tox. 4 H302 H302
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 (not available) H335
Muta. 1B H340 H340
Carc. 1B H350 H350
STOT RE 1 H372 (Nervous system) (Inhalation) H372
Flam. Gas 1 H220 H220 GHS02
GHS08
GHS06
GHS04
Dgr
Note U
State/Form
71 View details
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 H335
Muta. 1B H340 H340
Carc. 1B H350 H350
Flam. Gas 1 H220 H220 EUH006
Dgr
68 View details
H280 H280
Acute Tox. 4 H302 H302
Skin Irrit. 2 H315 H315
Eye Irrit. 2A H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 (respiratory sys...) H335
Muta. 1B H340 (Inhalation) H340
Carc. 1B H350 (Inhalation) H350
Flam. Gas 1 H220 H220 EUH006
GHS02
GHS08
GHS06
GHS04
Dgr
State/Form
48 View details
H280 H280
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 (respiratory sys...) H335
Muta. 1B H340 H340
Carc. 1B H350 H350
Flam. Gas 1 H220 H220 GHS02
GHS08
GHS06
GHS04
Dgr
State/Form
44 View details
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 (not specified) H335
Muta. 1B H340 H340
Carc. 1B H350  
Flam. Gas 1 H220 H220 EUH006
GHS02
GHS04
Dgr
Note U
State/Form
40 View details
H280 H280
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 (Respitatory Tra...) (Inhalation) H335
Muta. 1B H340  
Carc. 1B H350  
Flam. Gas 1 H220 H220 GHS02
GHS08
GHS06
Dgr
State/Form
36 View details
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 (Not applicable) H335
Muta. 1B H340 H340 (May cause genet...)
Carc. 1B H350 H350 (May cause cance...)
Flam. Gas 1 H220 H220 EUH006
GHS02
GHS08
GHS04
GHS06
Dgr
State/Form
36 View details
H280 H280
Acute Tox. 4 H302 H302
Skin Irrit. 2 H315 H315
Eye Irrit. 2A H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 (respiratory sys...) H335
Muta. 1B H340 (Inhalation) H340
Carc. 1B H350 (Inhalation) H350
Flam. Gas 1 H220 H220 GHS02
GHS08
GHS07
GHS06
GHS04
Dgr
31 View details
Press. Gas (Liq.) H280 H280
Acute Tox. 3 H301 H301
  H302
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 H335
Muta. 1B H340 H340
Carc. 1B H350 H350
STOT RE 1 H372 (central nervous...) (Inhalation) H372
Flam. Gas 1 H220 H220 EUH006
GHS02
GHS08
GHS07
GHS06
Dgr
25 View details
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
  H330
Acute Tox. 3 H331  
STOT SE 3 H335 (Respiratory tra...) H335
Muta. 1B H340 H340
Carc. 1B H350 H350
Flam. Gas 1 H220 H220 GHS02
GHS08
GHS06
GHS04
Dgr
State/Form
23 View details
H280  
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 2 H330 H330
STOT SE 3 H335 (not specified) H335
Muta. 1B H340 H340
Carc. 1B H350  
Flam. Gas 1 H220 H220 GHS02
GHS08
GHS04
GHS06
GHS07
Dgr
17 View details
H280 H280
Press. Gas (Comp.) H280 H280
Acute Tox. 4 H302 H302
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 H335
Muta. 1B H340 H340
Carc. 1B H350 H350
STOT RE 1 H372 (.) H372
Flam. Gas 1 H220 H220 GHS02
GHS08
GHS06
Dgr
State/Form
13 View details
H280 H280
Acute Tox. 4 H302 H302
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 (Respiratory sys...) H335
Muta. 1B H340 H340
Carc. 1B H350 H350
STOT RE 1 H372 (Central nervous...) H372
Flam. Gas 1 H220 H220 GHS02
GHS08
GHS06
GHS04
Dgr
State/Form
11 View details
H280 H280
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 H335
Muta. 1B H340 H340
Carc. 1B H350 H350
Flam. Gas 1 H220 H220 GHS02
GHS08
GHS04
GHS06
Dgr
11 View details
H280 H280
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 (Respiratory sys...) H335
Muta. 1B H340 H340
Carc. 1B H350 H350
Flam. Gas 1 H220 H220 EUH006
GHS02
GHS08
GHS04
GHS06
Dgr
7 View details
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 (respiratory org...) H335
Muta. 1B H340 H340
Carc. 1B H350 H350
Flam. Gas 1 H220 H220 (H220) GHS02
GHS08
GHS06
GHS04
Dgr
5 View details
H280  
Skin Irrit. 2 H315 H315 (H315)
Eye Irrit. 2 H319 H319 (H319)
Acute Tox. 3 H331 H331 (H331)
STOT SE 3 H335 (eyes, skin, res...) H335 (H335)
Muta. 1B H340 H340 (H340)
Carc. 1B H350 H350 (H350)
Flam. Gas 1 H220 H220 GHS02
GHS08
GHS04
GHS07
GHS06
Dgr
5 View details
H280 H280
Acute Tox. 4 H302 H302
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 (Unknown) H335
Muta. 1B H340 H340
Carc. 1B H350 H350
Flam. Gas 1 H220 H220 GHS02
GHS08
GHS04
GHS06
Dgr
Note E
State/Form
3 View details
H280 H280
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
  H335
Muta. 1B H340 H340
Carc. 1B H350 H350
Flam. Gas 1 H220 H220 GHS02
GHS08
GHS06
GHS04
Dgr
State/Form
2 View details
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
  H335
Muta. 1B H340 H340
Carc. 1B H350 H350
Flam. Gas 1 H220 H220 GHS02
GHS08
GHS04
GHS06
Dgr
State/Form
2 View details
  H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 (Lung) H335
  H340
Carc. 1B H350 H350
Flam. Gas 1 H220 H220 GHS02
GHS08
GHS06
Dgr
2 View details
Press. Gas (Liq.) H280 H280
Acute Tox. 4 H302 H302
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 H335
Muta. 1B H340 H340
Carc. 1B H350 H350
STOT RE 1 H372 H372
Flam. Gas 1 H220 H220 GHS02
GHS08
GHS06
Dgr
2 View details
Press. Gas (Liq.) H280 H280
Acute Tox. 4 H302 H302
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 H335
Muta. 1B H340 H340
Carc. 1B H350 H350
STOT RE 1 H372 (Nervous System) H372
Not Classified               1  
  H200 EUH006
GHS02
GHS08
GHS06
GHS04
Dgr
State/Form
1 View details
Flam. Gas 1 H220  
H280 H280
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 (Not available) H335
Muta. 1B H340 H340
Carc. 1B H350 H350
Flam. Gas 1 H220 H220 GHS02
GHS08
GHS07
GHS06
Dgr
1 View details
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
  H330
Acute Tox. 3 H331 H331
STOT SE 3 H335 (Respiratory tra...) H335
Muta. 1B H340 H340
Carc. 1B H350  
Flam. Gas 1 H220 H220 GHS02
GHS08
GHS04
GHS06
Dgr
State/Form
1 View details
H280 H280
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 (Respiratory tra...) H335
Muta. 1B H340 H340
Carc. 1B H350 H350
Flam. Gas 1 H220 H220 GHS02
GHS08
GHS04
GHS06
Dgr
State/Form
1 View details
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 (Unknown) H335
  H340
  H350
Flam. Gas 1 H220 H220 GHS02
GHS08
GHS06
GHS04
Dgr
1 View details
H280 H280
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 (Unknown) (Oral) H335
Muta. 1B H340 H340
Carc. 1B H350 H350
Flam. Gas 1 H220 H220 GHS02
GHS08
GHS06
Dgr
1 View details
Press. Gas (Liq.) H280 H280
Acute Tox. 4 H302 H302
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 H335
Muta. 1B H340 H340
Carc. 1B H350 H350
STOT RE 1 H372 (Nervous system) H372
Flam. Gas 1 H220 H220 GHS02
GHS08
GHS06
Dgr
Note U
1 View details
Press. Gas (Liq.) H280 H280
Acute Tox. 4 H302 H302
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H331 H331
STOT SE 3 H335 H335
Muta. 1B H340 H340
Carc. 1B H350 H350
STOT RE 1 H372 H372

Number of Aggregated Notifications: 36