Registered substances

Registered substances

Registered substances

Please note:

As of end June 2022 we have processed and published all dossiers that had been pending since 14 October 2021. While daily processing has resumed there remains a processing queue. New submissions will be at the back of the processing queue, and may be slightly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Name EC / List no. CAS no. Registration Status Registration type Submission type Total tonnage band Last Updated Details
4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 Active Full Joint ≥ 100 000 to < 1 000 000 tonnes 17-10-2022 View substance registered dossier
4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 Cease Manufacture Intermediate Joint Cease manufacture 15-04-2018 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 - View substance registered dossier
StonCor Europe Rue du Travail, 9 1400 Nivelles Belgium Belgium Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2016; 2018; 2019; 2020 View substance registered dossier
W. L. Gore & Associates GmbH Hermann-Oberth-Strasse 22 85640 Putzbrunn Germany Germany Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2019; 2022 View substance registered dossier
Ramboll Deutschland GmbH Werinherstraße 79 Gebäude 32a 81541 München Bayern Germany Germany Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 - View substance registered dossier
DOW BENELUX B.V. OR-10 Postbus 48 4530 AA Terneuzen Netherlands Netherlands Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2022 View substance registered dossier
Caplinq Europe B.V. Industrieweg 15E 1566JN Assendelft - Netherlands Netherlands Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 - View substance registered dossier
Covestro Deutschland AG OR CN_001554 Kaiser-Wilhelm-Allee 60 51373 Leverkusen Germany Germany Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2012; 2017; 2019; 2021 View substance registered dossier
Nesperta sp. z o.o. Rejtana 12 A 62-030 Luboń Poland Poland Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2019 View substance registered dossier
Jowat SE Ernst-Hilker-Str. 10 - 14 32758 Detmold NRW Germany Germany Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2022 View substance registered dossier
DOW BENELUX B.V. Postbus 48 4530 AA Terneuzen Netherlands Netherlands Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2012; 2013; 2016; 2019; 2022 View substance registered dossier
COVESTRO, S.L. C/. Feixa LLarga, 7 08040 Barcelona Spain Spain Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2012; 2017; 2019; 2021 View substance registered dossier
Chemservice S.A. (H5P7) 13, Fausermillen 6689 Mertert Luxembourg Luxembourg Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 - View substance registered dossier
BASF Polyurethanes GmbH Elastogranstr. 60 49448 Lemförde Niedersachsen Germany Germany Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2012; 2017 View substance registered dossier
Mitsui and Co. Deutschland G.M.B.H. Head Office (Düsseldorf) Herzogstrasse 15 D-40217 Düsseldorf Germany Germany Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2019; 2022 View substance registered dossier
TSE, OR for NPU Amstelplein 1 1096 HA Amsterdam Netherlands Netherlands Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2012; 2013; 2014; 2016; 2019; 2021 View substance registered dossier
Lubrizol Europe Coordination Center BVBA 33 Chaussee De Wavre 1945 Brussels Belgium Belgium Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2016; 2021 View substance registered dossier
Huntsman (Europe) BV - OR2 Everslaan 45 B-3078 Everberg Belgium Belgium Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2012; 2013; 2014; 2015; 2017; 2019; 2021 View substance registered dossier
Axalta Coating Systems Germany GmbH & Co. KG Christbusch 25 42285 Wuppertal Germany Germany Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 - View substance registered dossier
Specialty Electronic Materials Netherlands BV OR-1 Baanhoekweg 22 3313 LA Dordrecht Netherlands Netherlands Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2016; 2017 View substance registered dossier
PPG Europe B.V. in its legal capacity as Only Representative of PRC DeSoto International Inc. - OR5 Amsterdamseweg 14 1422 AD Uithoorn Netherlands Netherlands Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 - View substance registered dossier
Covestro Deutschland AG OR US_001257 Kaiser-Wilhelm-Allee 60 51373 Leverkusen Germany Germany Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2012; 2017; 2019; 2021 View substance registered dossier
Delrin Netherlands B.V. Baanhoekweg 22 3313 Dordrecht Netherlands Netherlands Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2022 View substance registered dossier
Celanese Europe BV The New Atrium Strawinskylaan 3105 1077 ZX Amsterdam Netherlands Netherlands Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2022 View substance registered dossier
PPG Europe B.V. - OR1 Amsterdamseweg 14 1422 AD Uithoorn Netherlands Netherlands Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 - View substance registered dossier
Kuraray Europe GmbH (OR1) Philipp-Reis-Str. 4 65795 Hattersheim Germany Germany Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2019; 2022 View substance registered dossier
BASF Antwerpen N.V. Haven 725, Scheldelaan 600 2040 Antwerpen 4 Antwerpen Belgium Belgium Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2012; 2018 View substance registered dossier
PPG Europe B.V. - OR3 Amsterdamseweg 14 1422 AD Uithoorn Netherlands Netherlands Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 - View substance registered dossier
Covestro Deutschland AG OR JP_000145 Kaiser-Wilhelm-Allee 60 51373 Leverkusen Germany Germany Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2019; 2021 View substance registered dossier
Lubrizol Advanced Materials Europe B.V.B.A Nijverheidsstraat 30 2260 Westerlo-Oevel Belgium Belgium Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2015; 2016; 2019; 2022 View substance registered dossier
Chemservice S.A. (TZ6C) 13, Fausermillen 6689 Mertert Luxembourg Luxembourg Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 - View substance registered dossier
Chemours Netherlands B.V. Baanhoekweg 22 3313 LA Dordrecht Netherlands Netherlands Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 - View substance registered dossier
FujiFilm Manufacturing Europe BV Oudenstaart 1 5047 TK Tilburg Netherlands Netherlands Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 - View substance registered dossier
Ravago Chemicals Netherlands BV Neptunusstraat 15 2132 JA Hoofddorp Netherlands Netherlands Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 - View substance registered dossier
BorsodChem Zrt. - OR Bolyai ter 1. H-3700 Kazincbarcika Hungary Hungary Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2012; 2013; 2014; 2016; 2017; 2019; 2021 View substance registered dossier
Lubrizol Europe Coordination Center BVBA 02 Chaussee De Wavre 1945 Brussels Belgium Belgium Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2015; 2016; 2019; 2020; 2022 View substance registered dossier
Henkel Global Supply Chain B.V. Gustav Mahlerlaan 2970 1081 LA Amsterdam Netherlands Netherlands Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2018; 2019 View substance registered dossier
W. L. Gore & Associates (UK) Ltd. Kirkton South Road Kirkton Campus EH54 7BT Livingston United Kingdom United Kingdom No longer Valid 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2021 View substance registered dossier
HUNTSMAN HOLLAND BV Merseyweg 10 3197 KG Botlek-Rotterdam Netherlands Netherlands Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2011; 2012; 2013; 2014; 2015; 2017; 2019; 2021 View substance registered dossier
Renishaw PLC New Mills GL12 8JR Wotton-under-Edge Gloucestershire United Kingdom United Kingdom No longer Valid 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2021 View substance registered dossier
Lohmann & Rauscher GmbH & Co. KG Irlicher Straße 55 56567 Neuwied Germany Germany Cease Manufacture 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2018 View substance registered dossier
Covestro Deutschland AG Kaiser-Wilhelm-Allee 60 51373 Leverkusen Germany Germany Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2012; 2017; 2019; 2021 View substance registered dossier
SAINT-GOBAIN INNOVATIVE MATERIALS BELGIUM SA AVENUE EINSTEIN 6 1300 WAVRE Belgium Belgium Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 - View substance registered dossier
CSI-OR52DUB CSI-Europe Block C Ardilaun Court, 112-114 St. Stephen’s Green D02 TD28 Dublin Ireland Ireland Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2018; 2019 View substance registered dossier
DOW BENELUX B.V. - OR1 Postbus 48 4530 AA Terneuzen Netherlands Netherlands Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2019; 2022 View substance registered dossier
3M Belgium BVBA/SPRL (OR1) Hermeslaan 7 1831 Diegem Belgium Belgium Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2013; 2016; 2017; 2019; 2022 View substance registered dossier
COIM SpA Via delle Azalee, 19 20090 Buccinasco (MI) Italy Italy Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2019; 2020 View substance registered dossier
Lubrizol Europe Coordination Center BVBA 19 Chaussee De Wavre 1945 Brussels Belgium Belgium Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2016; 2019 View substance registered dossier
Lubrizol Europe Coordination Center BVBA 30 Chaussee De Wavre 1945 Brussels Belgium Belgium Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2019 View substance registered dossier
BASF Italia S.p.A. Via Marconato 8 20811 Cesano Maderno Italy Italy Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2022 View substance registered dossier
AKZO Nobel Car Refinishes B.V. Rijksstraatweg 31 2170 BA Sassenheim Netherlands Netherlands Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 - View substance registered dossier
REACHLaw Ltd. Vänrikinkuja 3 JK 21 02600 Espoo Finland Finland Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2012; 2013; 2017; 2019; 2021 View substance registered dossier
Yordas GmbH Äußere Nürnberger Str. 62, 91301 Forchheim Germany Germany Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 - View substance registered dossier
SLM Solutions Group AG Estlandring 4 23560 Lübeck Germany Germany Cease Manufacture 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2022 View substance registered dossier
BorsodChem Bolyai ter 1 3700 Kazincbarcika Hungary Hungary Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2012; 2013; 2014; 2016; 2017; 2019; 2021 View substance registered dossier
Lubrizol France SAS 25 Quai de France 76100 ROUEN France France Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2016 View substance registered dossier
Huntsman (Europe) BV - OR8 Everslaan 45 B-3078 Everberg Belgium Belgium Active 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2018; 2019; 2021 View substance registered dossier
Arcerion GmbH Gabrielenstr. 15 80636 Muenchen Germany Germany Cease Manufacture 4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 2018 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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