Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 200-306-6 | CAS number: 57-00-1
Endpoint summary
Administrative data
Description of key information
Creatine is a colourless, crystalline, and odourless organic powder. It is solid at room temperature.
Creatine melts at 300-303°C with decomposition. The boiling point of Creatine cannot be determined because the test material decomposes before boiling. Creatine has a density of 1.33 g/cm³ at 25°C. The substance as manufactured has a median particle size of 114.02 µm. The vapour pressure of Creatine has not been determined because its melting point is above 300°C. However, the Hazardous Substances Data Bank (HSDB) reports a peer-reviewed, calculated value of 7.9E-4 mm Hg at 15 °C.
Creatine Monohydrate is a hydrophilic compound (log Kow -2 at 20°C) and is soluble in water (15.1 g/L at 20 °C). These data are read across to Creatine. As such, the solubility in organic solvents/fat is not considered a relevant property of this substance as it will essentially be insoluble in non-polar solvents. Creatine is not surface active.
Creatine Monohydrate is not susceptible to autoignition. These data are read-across to Creatine. Creatine is neither considered to be highly flammable nor to be an explosive.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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