Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: QSAR estimate. A more precise value is not useful due to clear hydrophily. Quoted by several peer-reviewed sources.
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
other: QSAR model
Title:
No information
Year:
2010
Bibliographic source:
EPI Suite - module WsKow

Materials and methods

Principles of method if other than guideline:
QSAR: EPI Suite's WsKow module was used with following input:
- SMILES = N(C)(C)N
- MP = -58°C
GLP compliance:
no
Type of method:
other: QSAR
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
N,N-dimethylhydrazine
EC Number:
200-316-0
EC Name:
N,N-dimethylhydrazine
Cas Number:
57-14-7
Molecular formula:
C2H8N2
IUPAC Name:
1,1-dimethylhydrazine

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
-1.19
Remarks on result:
other: temperature and pH not applicable (QSAR)

Applicant's summary and conclusion

Conclusions:
Log Kow = -1.19
Executive summary:

Using EPI Suite's WsKow module, the log Kow was estimated to be -1.19. This result has been quoted by peer-reviewed secondary sources like ChemIDPlus, HSDB, National Toxicology program.