Registration Dossier
Registration Dossier
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EC number: 200-592-2 | CAS number: 64-73-3
Endpoint summary
Administrative data
Description of key information
LD 50(oral, adult rats): 2372 mg/kg/day;
LD 50(oral, newborn rats (< 2 days)): 2107 mg/kg/day
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 2 372 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
One acute oral is available.
In the acute oral literature (EDWIN I. GOLDENTHAL, 1971), it presented consists primarily of data submitted in drug applications from pharmaceutial manufactures without a detailed specification. However, necessary experimetal data was provided in this study to evaluate the acute oral toxicity on test article. It has been indicated that LD50(oral, adult rats) is 2372 mg/kg and LD50 (oral, newborn rats(< 2 days)) is 2107 mg/kg. Based on the available results, the LD50 of oral is derived as below:
LD 50(oral, adult rats): 2372 mg/kg/day;
LD 50(oral, newborn rats (< 2 days)): 2107 mg/kg/day
Justification for classification or non-classification
Based on the available data, the test article can not be classified according to CLP (EC No. regulation 1272/2008).
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