Registration Dossier
Registration Dossier
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EC number: 201-171-6 | CAS number: 79-04-9
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
Weight of evidence: Ames test
1. Read-Across as developed in Toolbox (version 1.1.02): with and without S9
2. Read-across from structural analogues with and without S9
3. Checking of mutagenicity for hydrolysis compound
The read across analysis based on the properties of analogues shows that this chemical is not mutagenic.
Chloroacetyl chloride hydrolises forming monochloroacetic acid (CASRN 79-11-8). This substance has been tested for mutagenicity within National Toxicology Program. Monochloroacetic acid was not mutagenic in Salmonella typhimurium strains TA100, TA1535, TA1537, or TA98, with or without exogenous metabolic activation (S9).
Short description of key information:
Weight of evidence: Ames test
1. Read-Across as developed in Toolbox (version 1.1.02): with and without S9
2. Read-across from structural analogues with and without S9
3. Checking of mutagenicity for hydrolysis compound
The read across analysis based on the properties of analogues shows that this chemical is not mutagenic.
Chloroacetyl chloride hydrolises forming monochloroacetic acid (CASRN 79-11-8). This substance has been tested for mutagenicity within National Toxicology Program. Monochloroacetic acid was not mutagenic in Salmonella typhimurium strains TA100, TA1535, TA1537, or TA98, with or without exogenous metabolic activation (S9).
Endpoint Conclusion:
Justification for classification or non-classification
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