Methyl 2-naphthyl ether

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

Experimental test result performed using standard OECD test guidelines

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Principles of method if other than guideline:

The water solubility determination of test chemical was done as per the OECD Guideline 105 (Water Solubility) and by spectrophotometric analytical method as per OECD 101.

GLP compliance:

no

Type of method:

other: spectrophotometric analytical method

Key result

Water solubility:

49.23 mg/L

Conc. based on:

test mat.

Temp.:

25 °C

pH:

3.99

Remarks on result:

other: Other details not known

ANALYTICAL DETERMINATION

PRELIMINARY TEST AT 24 h

Concentration obtained (mg/L)		Average	Absorbance	Average	Total Dilution factor(if any)	Water Solubility Value by Standard Curve (mg/L)	Average
R1	4.82	4.82	1.37	1.37	20	96.4	96.4 mg/l
R2	4.82		1.37		20	96.4

 

CONFIRMATORY TEST AT 24, 48 AND 72 h

Sample stirring (hours)	Concentration obtained		Average	Absorbance	Average	Dilution factor	Water Solubility Value by Standard Curve (mg/L)	Average
24 h	R1	2.47	2.48	0.70	0.70	20	49.4	49.6 mg/L
24 h	R2	2.49		0.71			49.8
48 h	R1	1.60	2.59	0.45	0.73	20	32	51.8 mg/L
48 h	R2	3.58		1.02			71.6
72 h	R1	2.20	2.31	0.62	0.65	20	44	46.3 mg/L
72 h	R2	2.43		0.69			48.6

 

Calculations:

The water solubility for 24 h, 48 h and 72 h was calculated as follows: Mean water solubility value for 24 h + 48 h + 72 h run sample.

= (49.6+51.8+46.3)/3

= 49.23 mg/L

pH

pH
	Preliminary test	Confirmatory test
	24 h	24 h	48 h	72 h
R1	3.47	4.06	4.08	3.84
R2	3.62	4.03	4.04	3.94

Conclusions:

The water solubility determination of test chemical was done by spectrophotometric method. The water solubility was determined to be 49.23 mg/L.

Executive summary:

The water solubility determination of test chemical was done as per the OECD Guideline 105 (Water Solubility) and by spectrophotometric analytical method as per OECD 101. The solubility of test chemical in water was determined to be 49.23 mg/l. On the basis of this value, test chemical was considered to be slightly soluble in water.

Description of key information

Based on the available data from study report,the water solubility determination of test chemical was done as per the OECD Guideline 105 (Water Solubility) and by spectrophotometric analytical method as per OECD 101. The solubility of test chemical in water was determined to be 49.23 mg/l. On the basis of this value, test chemical was considered to be slightly soluble in water.

Key value for chemical safety assessment

Water solubility:

49.23 mg/L

at the temperature of:

25 °C

Additional information

Based on the available data from study report,the water solubility determination of test chemical was done as per the OECD Guideline 105 (Water Solubility) and by spectrophotometric analytical method as per OECD 101. The solubility of test chemical in water was determined to be 49.23 mg/l. On the basis of this value, test chemical was considered to be slightly soluble in water.