Registration Dossier
Registration Dossier
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EC number: 202-503-2 | CAS number: 96-37-7
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- A discussion and report on the read across strategy is given as an attachment in IUCLID Section 13.
- Reason / purpose for cross-reference:
- read-across: supporting information
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
- Version / remarks:
- July 17, 1992
- GLP compliance:
- yes (incl. QA statement)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, adapted
- Duration of test (contact time):
- 28 d
- Initial conc.:
- ca. 100 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- Measurement and analysis
(1) Measurement of biochemical oxygen Demand (BOD) by a closed-system oxygen consumption measurement system
(2) Analysis of test substance by Gaschromatography (GC) - Key result
- Parameter:
- % degradation (O2 consumption)
- Remarks:
- according BOD resp. GC
- Value:
- ca. 93 - ca. 94
- Sampling time:
- 28 d
- Key result
- Parameter:
- BOD5
- Value:
- >= 105 - <= 121 mg O2/g test mat.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- Test item (2-methylpentane) is readily biodegradable within 28d.
- Executive summary:
Test item (2-methylpentane) is readily biodegradable within 28d.
Reference
Description of key information
Biodegradation:
There is no key data available for Methylcyclopentane. Key read across data is available for a structural analogue 2-methylpentane. Additionally, supporting QSAR data for methylcyclopentane.
An OECD Guideline 301 C (Ready Biodegradability: Modified MITI) test was conducted using 2-methylpentane.The test substance was 93-94% degraded at the end of 28 days and is therefore considered to be readily biodegradable as per the strict guidelines of the OECD test. Supporting this positive results, the QSAR predictions forMethylcyclopentane also determined it to be readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
There is no key data available for Methylcyclopentane. Key read across data is available for a structural analogue 2-methylpentane. Additionally, supporting QSAR data for methylcyclopentane is also available.
An OECD Guideline 301 C (Ready Biodegradability: Modified MITI test (CERI, 2002) was conducted using 2-methylpentane. The test substance was 93-94% degraded at the end of 28 days and was therefore considered to be readily biodegradable.
Methylcyclopentane was also determined to be readily biodegradable based on QSAR prediction.
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