Registration Dossier
Registration Dossier
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EC number: 203-788-6 | CAS number: 110-65-6
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
72 hour EC50, growth rate, Desdemodesmus subspicatus: 1058 mg/L
72 hour EC20, growth rate, Desdemodesmus subspicatus: 508 mg/L
72 hour EC10, growth rate, Desdemodesmus subspicatus: 346 mg/L
72 hour NOEC, growth rate, Desdemodesmus subspicatus: 125 mg/L
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 1 058 mg/L
- EC10 or NOEC for freshwater algae:
- 125 mg/L
Additional information
The 1,4 -butynediol 72 hour NOEC for growth rate of the freshwater alga (Desdemodesmus subspicatus) provided in a DIN 38412 guideline study is 125 mg/L, the 72 hour EC10 is 346 mg/L, and the 72 hour EC50 is 1058 mg/L (BASF AG 1988). These data are supported by the results of a guideline-equivalent study with Scenedesmus subspicatus which yielded a 72 hour IC50 of >100 mg/L (Tisler, et. al., 2003).
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