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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Dissociation constant

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Administrative data

Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Based on data, which can be considered reliable with restrictions.

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
N/A
Author:
Agren, Svensk Kemisk Tidskrift
Year:
1956
Bibliographic source:
SKTIAF, 68, <1956>, 181,187
Reference Type:
publication
Title:
N/A
Author:
Svensk Kemisk Tidskrift
Year:
1956
Bibliographic source:
SKTIAF, 68, <1956>, 189,191
Reference Type:
review article or handbook
Title:
N/A
Author:
Elsevier Information Systems GmbH, Germany
Year:
2016
Bibliographic source:
ReaxysFile
Report date:
2016

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
The dissociation constant was determined with spectrophotometric measurement.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2'-hydroxyacetophenone
EC Number:
204-288-0
EC Name:
2'-hydroxyacetophenone
Cas Number:
118-93-4
Molecular formula:
C8H8O2
IUPAC Name:
1-(2-hydroxyphenyl)ethan-1-one

Results and discussion

Dissociating properties:
not determined
Dissociation constant
pKa:
10.06
Temp.:
20 °C
Remarks on result:
other: Solvent: water

Applicant's summary and conclusion