Registration Dossier
Registration Dossier
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EC number: 204-409-7 | CAS number: 120-57-0
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The 48h-EC50 was 52 mg/L based on analytically confirmed nominal concentrations (95% confidence interval between 45 and 64 mg/L).
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 52 mg/L
Additional information
Short-term toxicity to aquatic invertebrates Daphnia magna was assessed according to OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test), and EU Method C.2 (Acute Toxicity for Daphnia) and in compliance with GLP. Daphnia were exposed under static conditions to the substance at concentrations of 4.6, 10, 22, 46, and 100 mg/L in freshwater.
The test was performed with 5 daphnia per vessel. For each concentration, the percentage of immobilisation at 24 hours and 48 hours was recorded, and test concentrations were confirmed by HPLC analysis.
After 48 hours NOEC was 22 mg/L and EC50 was 52 mg/L (nominal values).
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