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Diss Factsheets
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EC number: 204-466-8 | CAS number: 121-34-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: screening test, other
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 29-11-2002 to 28-12-2002
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Remarks:
- Screening test.
- Qualifier:
- according to guideline
- Guideline:
- ISO 14593:1999 (Water quality - Evaluation of ultimate aerobic biodegradability of organic compounds in aqueous medium - Method by analysis of inorganic carbon in sealed vessels (CO2 headspace test))
- Version / remarks:
- Screening test.
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: 01JAT1272
- Expiration date of the lot/batch: no data
- Purity test date: no data
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: at 4°C.
- Stability under test conditions: yes - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, adapted
- Details on inoculum:
- Preparation of activated sludge: The inoculum was prepared from activated sludge taken from a domestic effluent treatment plant (Jundiai, Brazil). Coarse particles have been removed by filtration. The sludge was then centrifuged and washed and the pellets returned suspended in culture medium. They were used as inoculum at a concentration of 4 mg / l (dry matter).
No other information on the inoculum available. - Duration of test (contact time):
- 28 d
- Initial conc.:
- 20 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- TOC removal
- Details on study design:
- TEST CONDITIONS: no data
TEST SYSTEM
- Volume of test solution: 120 mL
- Number of culture flasks/concentration: 2
- magnetic stirrer
- Test temperature: 22°C
SAMPLING: No data
CONTROL AND BLANK SYSTEM
- Inoculum blank: 1 test vessel with 120 mL of basal culture medium (sludge)
- sludge + test substance at 20 mg/L
- reference substance: sludge + sodium benzoate at 20 mg/L
- Concentration of activated sludge (as suspended solid concentration): 20 mg/l - Reference substance:
- other: Sodium Benzoate
- Key result
- Parameter:
- % degradation (TOC removal)
- Value:
- 97.5
- Sampling time:
- 28 d
- Key result
- Parameter:
- % degradation (TOC removal)
- Value:
- 73
- Sampling time:
- 5 d
- Results with reference substance:
- % degradation (TOC removal): 96.9% after 28 days.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The corresponding percentages of biodegradation obtained after 5 and 28 days were 73% and 97.5% respectively. Under the test conditions of this study, Vanillic acid is therefore considered as readily biodegradable.
- Executive summary:
The biodegradation of Vanillic acid (initial concentration of 20 mg/L) was studied during 28 days according to ISO 14593 (Reliability 2, Not GLP, Solvay Internal Report). Inoculum used in the test was an activated sludge at a concentration of 4 mg/Lpreparedfrom activated sludge taken from an aeration tank of a domestic effluent treatment plant (Jundiai - Brazil).
The percentage of biodegradation was estimated by the Total Organic Carbon (TOC). The corresponding percentages of biodegradation obtained after 5 and 28 days were 73% and 97.5% respectively. Under the test conditions of this study, Vanillic acid is therefore considered as readily biodegradable.
Reference
Description of key information
One study was available and considered as the key study. The biodegradation of Vanillic acid (initial concentration of 20 mg/L) was studied during 28 days according to ISO 14593 (Reliability 2, Not GLP). Inoculum used in the test was an activated sludge at a concentration of 4 mg/Lprepared from activated sludge taken from an aeration tank of a domestic effluent treatment plant (Jundiai, Brazil).
The percentage of biodegradation was estimated by the Total Organic Carbon (TOC). The corresponding percentages of biodegradation obtained after 5 and 28 days were 73% and 97.5% respectively. Under the test conditions of this study, Vanillic acid is therefore considered as readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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