Propionaldehyde

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1988

Report date:

1988

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

EU Method C.2 (Acute Toxicity for Daphnia)

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

Propionaldehyde

EC Number:

204-623-0

EC Name:

Propionaldehyde

Cas Number:

123-38-6

Molecular formula:

C3H6O

IUPAC Name:

propanal

Sampling and analysis

Analytical monitoring:

no

Test solutions

Vehicle:

no

Details on test solutions:

• A stock solution (500 mg/L) was prepared and subsequently diluted to achieve the test concentrations

Test organisms

Test organisms (species):

Daphnia magna

Details on test organisms:

• Source: Institut National de Recherche Chimique Appliquee (France), breed at the testing facility since 1987
• Age at study initiation: 0-24h
• Control group: yes

Study design

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

48 h

Test conditions

Hardness:

2.61 mmol/L

Test temperature:

292-294 K

pH:

ranged from 7.14 to 8.15 in all test vessels including the control

Nominal and measured concentrations:

Nominal concentrations in mg/L: 7.81, 15.6, 31.2, 62.5, 125, 250 and 500 mg/L

Details on test conditions:

• Exposure vessel type: test-tube with flattened bottom, volume 10 mL, four vessels per test concentration
• Dilution water source: filtered tap water
• Dilution water chemistry (hardness: 2.7 +/- 0.5 mmol/L; pH: 7.7-8.3, Ca/Mg ratio 4:1)
• Test design: four replicates per treatment, five individuals per replicate, seven concentrations
• Method of calculating mean measured concentrations: statistical method of Spearman-Kaerber

Results and discussion

Effect concentrations

Effect concentrations 1

Duration:

48 h

Dose descriptor:

EC0

Effect conc.:

62.5 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mobility

Effect concentrations 2

Duration:

48 h

Dose descriptor:

EC50

Effect conc.:

88.7 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mobility

Remarks on result:

other: 75.55 - 104.07 mg/L

Effect concentrations 3

Duration:

48 h

Dose descriptor:

EC100

Effect conc.:

250 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mobility

Any other information on results incl. tables

Effect concentrations after 24 hours: 
EC50: 134.3 [95%: 115.31 - 156.41]; EC0: 62.5; EC100: 250