Registration Dossier
Registration Dossier
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EC number: 204-639-8 | CAS number: 123-63-7
Toxicity to microorganisms
Administrative data
- Endpoint:
- toxicity to microorganisms
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- March 1990
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: According to UBA-method to determine the toxic potential of chemical substances for water systems, Sept. 1979, Heft 10, federal environmental agency and GLP Standard.
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 990
- Report date:
- 1990
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: UBA-method, Heft 10, federal environmental agency
- Principles of method if other than guideline:
- SOP MIB/M/31 Determination of biological effects of toxic substances against bacteria.
- GLP compliance:
- yes
Test material
- Reference substance name:
- 2,4,6-trimethyl-1,3,5-trioxane
- EC Number:
- 204-639-8
- EC Name:
- 2,4,6-trimethyl-1,3,5-trioxane
- Cas Number:
- 123-63-7
- Molecular formula:
- C6H12O3
- IUPAC Name:
- 2,4,6-trimethyl-1,3,5-trioxane
- Test material form:
- other: liquid
- Details on test material:
- Name used for report: P0087
Batch No.: Tk1-19.9.89
Purity: 99.7%
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Pseudomonas putida
Study design
- Test type:
- not specified
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 18 h
Results and discussion
Effect concentrations
- Duration:
- 18 h
- Dose descriptor:
- EC10
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- In the presence of test item P0087, starting with a concentration of 1000 mg/L and below, no inhibition of growth for Pseudomonas putida could be
detected. Therefore, the EC10 (starting concentration) after 18 h incubation is > 1000 mg/L. - Executive summary:
- A microorganisms test with Pseudomonas putida as test species was performed in year 1990 according to UBA-method to determine the toxic potential of P0087 for water systems. In the presence of test item P0087, starting with a concentration of 1000 mg/L and below, no inhibition of growth for Pseudomonas putida could be detected. Therefore, the EC10 (starting concentration) after 18 h incubation is > 1000 mg/L.
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